-
1
-
-
77951240586
-
Network properties of complex human disease genes identified through genome-wide association studies
-
Barrenas F, Chavali S, Holme P, Mobini R, Benson M, (2009) Network properties of complex human disease genes identified through genome-wide association studies. PLoS One 4: e8090.
-
(2009)
PLoS One
, vol.4
-
-
Barrenas, F.1
Chavali, S.2
Holme, P.3
Mobini, R.4
Benson, M.5
-
2
-
-
41949118715
-
Network properties of genes harboring inherited disease mutations
-
Feldman I, Rzhetsky A, Vitkup D, (2008) Network properties of genes harboring inherited disease mutations. Proc Natl Acad Sci U S A 105: 4323-4328.
-
(2008)
Proc Natl Acad Sci U S A
, vol.105
, pp. 4323-4328
-
-
Feldman, I.1
Rzhetsky, A.2
Vitkup, D.3
-
3
-
-
48249139449
-
Multiple sclerosis: An immune or neurodegenerative disorder?
-
Trapp BD, Nave KA, (2008) Multiple sclerosis: An immune or neurodegenerative disorder? Annu Rev Neurosci 31: 247-269.
-
(2008)
Annu Rev Neurosci
, vol.31
, pp. 247-269
-
-
Trapp, B.D.1
Nave, K.A.2
-
4
-
-
67249117049
-
Potential etiologic and functional implications of genome-wide association loci for human diseases and traits
-
Hindorff LA, Sethupathy P, Junkins HA, Ramos EM, Mehta JP, et al. (2009) Potential etiologic and functional implications of genome-wide association loci for human diseases and traits. Proc Natl Acad Sci U S A 106: 9362-9367.
-
(2009)
Proc Natl Acad Sci U S A
, vol.106
, pp. 9362-9367
-
-
Hindorff, L.A.1
Sethupathy, P.2
Junkins, H.A.3
Ramos, E.M.4
Mehta, J.P.5
-
5
-
-
59249097905
-
Shared susceptibility variations in autoimmune diseases: A brief perspective on common issues
-
Seldin MF, Amos CI, (2009) Shared susceptibility variations in autoimmune diseases: A brief perspective on common issues. Genes Immun 10: 1-4.
-
(2009)
Genes Immun
, vol.10
, pp. 1-4
-
-
Seldin, M.F.1
Amos, C.I.2
-
6
-
-
77950355043
-
Unraveling the genetics of autoimmunity
-
Zenewicz LA, Abraham C, Flavell RA, Cho JH, (2010) Unraveling the genetics of autoimmunity. Cell 140: 791-797.
-
(2010)
Cell
, vol.140
, pp. 791-797
-
-
Zenewicz, L.A.1
Abraham, C.2
Flavell, R.A.3
Cho, J.H.4
-
7
-
-
59149093799
-
Variation within the CLEC16A gene shows consistent disease association with both multiple sclerosis and type 1 diabetes in sardinia
-
Zoledziewska M, Costa G, Pitzalis M, Cocco E, Melis C, et al. (2009) Variation within the CLEC16A gene shows consistent disease association with both multiple sclerosis and type 1 diabetes in sardinia. Genes Immun 10: 15-17.
-
(2009)
Genes Immun
, vol.10
, pp. 15-17
-
-
Zoledziewska, M.1
Costa, G.2
Pitzalis, M.3
Cocco, E.4
Melis, C.5
-
8
-
-
34548299105
-
Risk alleles for multiple sclerosis identified by a genomewide study
-
International Multiple Sclerosis Genetics Consortium
-
Hafler DA, Compston A, Sawcer S, Lander ES, et al. International Multiple Sclerosis Genetics Consortium (2007) Risk alleles for multiple sclerosis identified by a genomewide study. N Engl J Med 357: 851-862.
-
(2007)
N Engl J Med
, vol.357
, pp. 851-862
-
-
Hafler, D.A.1
Compston, A.2
Sawcer, S.3
Lander, E.S.4
-
9
-
-
34548367511
-
Large-scale genetic fine mapping and genotype-phenotype associations implicate polymorphism in the IL2RA region in type 1 diabetes
-
Lowe CE, Cooper JD, Brusko T, Walker NM, Smyth DJ, et al. (2007) Large-scale genetic fine mapping and genotype-phenotype associations implicate polymorphism in the IL2RA region in type 1 diabetes. Nat Genet 39: 1074-1082.
-
(2007)
Nat Genet
, vol.39
, pp. 1074-1082
-
-
Lowe, C.E.1
Cooper, J.D.2
Brusko, T.3
Walker, N.M.4
Smyth, D.J.5
-
10
-
-
70449470314
-
The genetics of autoimmune diseases: A networked perspective
-
Baranzini SE, (2009) The genetics of autoimmune diseases: A networked perspective. Curr Opin Immunol 21: 596-605.
-
(2009)
Curr Opin Immunol
, vol.21
, pp. 596-605
-
-
Baranzini, S.E.1
-
11
-
-
60549085927
-
Gene-wide analyses of genome-wide association data sets: Evidence for multiple common risk alleles for schizophrenia and bipolar disorder and for overlap in genetic risk
-
Moskvina V, Craddock N, Holmans P, Nikolov I, Pahwa JS, et al. (2009) Gene-wide analyses of genome-wide association data sets: Evidence for multiple common risk alleles for schizophrenia and bipolar disorder and for overlap in genetic risk. Mol Psychiatry 14: 252-260.
-
(2009)
Mol Psychiatry
, vol.14
, pp. 252-260
-
-
Moskvina, V.1
Craddock, N.2
Holmans, P.3
Nikolov, I.4
Pahwa, J.S.5
-
12
-
-
32244434299
-
Comprehensive analysis of pathway or functionally related gene expression in the national cancer institute's anticancer screen
-
Huang R, Wallqvist A, Covell DG, (2006) Comprehensive analysis of pathway or functionally related gene expression in the national cancer institute's anticancer screen. Genomics 87: 315-328.
-
(2006)
Genomics
, vol.87
, pp. 315-328
-
-
Huang, R.1
Wallqvist, A.2
Covell, D.G.3
-
13
-
-
77950339092
-
Integrating pathway analysis and genetics of gene expression for genome-wide association studies
-
Zhong H, Yang X, Kaplan LM, Molony C, Schadt EE, (2010) Integrating pathway analysis and genetics of gene expression for genome-wide association studies. Am J Hum Genet 86: 581-591.
-
(2010)
Am J Hum Genet
, vol.86
, pp. 581-591
-
-
Zhong, H.1
Yang, X.2
Kaplan, L.M.3
Molony, C.4
Schadt, E.E.5
-
14
-
-
84864288185
-
A pathway-based view of human diseases and disease relationships
-
Li Y, Agarwal P, (2009) A pathway-based view of human diseases and disease relationships. PLoS One 4: e4346.
-
(2009)
PLoS One
, vol.4
-
-
Li, Y.1
Agarwal, P.2
-
15
-
-
65549084289
-
Pathway and network-based analysis of genome-wide association studies in multiple sclerosis
-
Baranzini SE, Galwey NW, Wang J, Khankhanian P, Lindberg R, et al. (2009) Pathway and network-based analysis of genome-wide association studies in multiple sclerosis. Hum Mol Genet 18: 2078-2090.
-
(2009)
Hum Mol Genet
, vol.18
, pp. 2078-2090
-
-
Baranzini, S.E.1
Galwey, N.W.2
Wang, J.3
Khankhanian, P.4
Lindberg, R.5
-
16
-
-
27144470749
-
T-cells in alzheimer's disease
-
Town T, Tan J, Flavell RA, Mullan M, (2005) T-cells in alzheimer's disease. Neuromolecular Med 7: 255-264.
-
(2005)
Neuromolecular Med
, vol.7
, pp. 255-264
-
-
Town, T.1
Tan, J.2
Flavell, R.A.3
Mullan, M.4
-
17
-
-
0029811901
-
Arthritis and anti-inflammatory agents as possible protective factors for alzheimer's disease: A review of 17 epidemiologic studies
-
McGeer PL, Schulzer M, McGeer EG, (1996) Arthritis and anti-inflammatory agents as possible protective factors for alzheimer's disease: A review of 17 epidemiologic studies. Neurology 47: 425-432.
-
(1996)
Neurology
, vol.47
, pp. 425-432
-
-
McGeer, P.L.1
Schulzer, M.2
McGeer, E.G.3
-
18
-
-
43149102747
-
Protective effects of NSAIDs on the development of alzheimer disease
-
Vlad SC, Miller DR, Kowall NW, Felson DT, (2008) Protective effects of NSAIDs on the development of alzheimer disease. Neurology 70: 1672-1677.
-
(2008)
Neurology
, vol.70
, pp. 1672-1677
-
-
Vlad, S.C.1
Miller, D.R.2
Kowall, N.W.3
Felson, D.T.4
-
19
-
-
33747890559
-
The brain as a target of inflammation: Common pathways link inflammatory and neurodegenerative diseases
-
Zipp F, Aktas O, (2006) The brain as a target of inflammation: Common pathways link inflammatory and neurodegenerative diseases. Trends Neurosci 29: 518-527.
-
(2006)
Trends Neurosci
, vol.29
, pp. 518-527
-
-
Zipp, F.1
Aktas, O.2
-
20
-
-
77952322955
-
Loss of epidermal growth factor regulation by cobalamin in multiple sclerosis
-
Scalabrino G, Galimberti D, Mutti E, Scalabrini D, Veber D, et al. (2010) Loss of epidermal growth factor regulation by cobalamin in multiple sclerosis. Brain Res 1333: 64-71.
-
(2010)
Brain Res
, vol.1333
, pp. 64-71
-
-
Scalabrino, G.1
Galimberti, D.2
Mutti, E.3
Scalabrini, D.4
Veber, D.5
-
21
-
-
77949883177
-
Epidermal growth factor increases prostaglandin E2 production via ERK1/2 MAPK and NF-kappaB pathway in fibroblast like synoviocytes from patients with rheumatoid arthritis
-
Nah SS, Won HJ, Ha E, Kang I, Cho HY, et al. (2010) Epidermal growth factor increases prostaglandin E2 production via ERK1/2 MAPK and NF-kappaB pathway in fibroblast like synoviocytes from patients with rheumatoid arthritis. Rheumatol Int 30: 443-449.
-
(2010)
Rheumatol Int
, vol.30
, pp. 443-449
-
-
Nah, S.S.1
Won, H.J.2
Ha, E.3
Kang, I.4
Cho, H.Y.5
-
22
-
-
0024466345
-
Nerve and epidermal growth factors induce the release of the alzheimer amyloid precursor from PC 12 cell cultures
-
Refolo LM, Salton SR, Anderson JP, Mehta P, Robakis NK, (1989) Nerve and epidermal growth factors induce the release of the alzheimer amyloid precursor from PC 12 cell cultures. Biochem Biophys Res Commun 164: 664-670.
-
(1989)
Biochem Biophys Res Commun
, vol.164
, pp. 664-670
-
-
Refolo, L.M.1
Salton, S.R.2
Anderson, J.P.3
Mehta, P.4
Robakis, N.K.5
-
23
-
-
33845534764
-
Downregulation of EGF receptor signaling in pancreatic islets causes diabetes due to impaired postnatal beta-cell growth
-
Miettinen PJ, Ustinov J, Ormio P, Gao R, Palgi J, et al. (2006) Downregulation of EGF receptor signaling in pancreatic islets causes diabetes due to impaired postnatal beta-cell growth. Diabetes 55: 3299-3308.
-
(2006)
Diabetes
, vol.55
, pp. 3299-3308
-
-
Miettinen, P.J.1
Ustinov, J.2
Ormio, P.3
Gao, R.4
Palgi, J.5
-
24
-
-
0034649608
-
Attenuation of FGF signalling in mouse beta-cells leads to diabetes
-
Hart AW, Baeza N, Apelqvist A, Edlund H, (2000) Attenuation of FGF signalling in mouse beta-cells leads to diabetes. Nature 408: 864-868.
-
(2000)
Nature
, vol.408
, pp. 864-868
-
-
Hart, A.W.1
Baeza, N.2
Apelqvist, A.3
Edlund, H.4
-
25
-
-
77949912530
-
Expression of insulin-like growth factor-1 and insulin-like growth factor binding proteins in the serum and cerebrospinal fluid of patients with parkinson's disease
-
Mashayekhi F, Mirzajani E, Naji M, Azari M, (2010) Expression of insulin-like growth factor-1 and insulin-like growth factor binding proteins in the serum and cerebrospinal fluid of patients with parkinson's disease. J Clin Neurosci 17: 623-627.
-
(2010)
J Clin Neurosci
, vol.17
, pp. 623-627
-
-
Mashayekhi, F.1
Mirzajani, E.2
Naji, M.3
Azari, M.4
-
26
-
-
67149139990
-
The role of IGF-1 receptor and insulin receptor signaling for the pathogenesis of alzheimer's disease: From model organisms to human disease
-
Freude S, Schilbach K, Schubert M, (2009) The role of IGF-1 receptor and insulin receptor signaling for the pathogenesis of alzheimer's disease: From model organisms to human disease. Curr Alzheimer Res 6: 213-223.
-
(2009)
Curr Alzheimer Res
, vol.6
, pp. 213-223
-
-
Freude, S.1
Schilbach, K.2
Schubert, M.3
-
27
-
-
71949112504
-
Increased tau phosphorylation and cleavage in mouse models of type 1 and type 2 diabetes
-
Kim B, Backus C, Oh S, Hayes JM, Feldman EL, (2009) Increased tau phosphorylation and cleavage in mouse models of type 1 and type 2 diabetes. Endocrinology 150: 5294-5301.
-
(2009)
Endocrinology
, vol.150
, pp. 5294-5301
-
-
Kim, B.1
Backus, C.2
Oh, S.3
Hayes, J.M.4
Feldman, E.L.5
-
28
-
-
77952585217
-
Type 1 diabetes exaggerates features of alzheimer's disease in APP transgenic mice
-
Jolivalt CG, Hurford R, Lee CA, Dumaop W, Rockenstein E, et al. (2010) Type 1 diabetes exaggerates features of alzheimer's disease in APP transgenic mice. Exp Neurol 223: 422-431.
-
(2010)
Exp Neurol
, vol.223
, pp. 422-431
-
-
Jolivalt, C.G.1
Hurford, R.2
Lee, C.A.3
Dumaop, W.4
Rockenstein, E.5
-
29
-
-
67649729196
-
Vascular factors in diabetes and alzheimer's disease
-
Taguchi A, (2009) Vascular factors in diabetes and alzheimer's disease. J Alzheimers Dis 16: 859-864.
-
(2009)
J Alzheimers Dis
, vol.16
, pp. 859-864
-
-
Taguchi, A.1
-
30
-
-
0026074976
-
Intrathecal immune response in patients with the post-polio syndrome
-
Sharief MK, Hentges R, Ciardi M, (1991) Intrathecal immune response in patients with the post-polio syndrome. N Engl J Med 325: 749-755.
-
(1991)
N Engl J Med
, vol.325
, pp. 749-755
-
-
Sharief, M.K.1
Hentges, R.2
Ciardi, M.3
-
31
-
-
0032704934
-
The function of tumour necrosis factor and receptors in models of multi-organ inflammation, rheumatoid arthritis, multiple sclerosis and inflammatory bowel disease
-
Kollias G, Douni E, Kassiotis G, Kontoyiannis D, (1999) The function of tumour necrosis factor and receptors in models of multi-organ inflammation, rheumatoid arthritis, multiple sclerosis and inflammatory bowel disease. Ann Rheum Dis 58 (Suppl 1): I32-9.
-
(1999)
Ann Rheum Dis
, vol.58
, Issue.SUPPL. 1
-
-
Kollias, G.1
Douni, E.2
Kassiotis, G.3
Kontoyiannis, D.4
-
32
-
-
62849115074
-
How do the efficacy and safety of abatacept and infliximab compare in the treatment of active RA?
-
Taylor PC, (2009) How do the efficacy and safety of abatacept and infliximab compare in the treatment of active RA? Nat Clin Pract Rheumatol 5: 126-127.
-
(2009)
Nat Clin Pract Rheumatol
, vol.5
, pp. 126-127
-
-
Taylor, P.C.1
-
33
-
-
0033546665
-
TNF neutralization in MS: Results of a randomized, placebo-controlled multicenter study. the lenercept multiple sclerosis study group and the university of british columbia MS/MRI analysis group
-
(1999) TNF neutralization in MS: Results of a randomized, placebo-controlled multicenter study. the lenercept multiple sclerosis study group and the university of british columbia MS/MRI analysis group. Neurology 53: 457-465.
-
(1999)
Neurology
, vol.53
, pp. 457-465
-
-
-
34
-
-
0032734010
-
Apoptotic and effector pathways in autoimmunity
-
Chervonsky AV, (1999) Apoptotic and effector pathways in autoimmunity. Curr Opin Immunol 11: 684-688.
-
(1999)
Curr Opin Immunol
, vol.11
, pp. 684-688
-
-
Chervonsky, A.V.1
-
35
-
-
34548306413
-
Apoptotic signal transduction and T cell tolerance
-
Gatzka M, Walsh CM, (2007) Apoptotic signal transduction and T cell tolerance. Autoimmunity 40: 442-452.
-
(2007)
Autoimmunity
, vol.40
, pp. 442-452
-
-
Gatzka, M.1
Walsh, C.M.2
-
36
-
-
64249144009
-
(Pre)diabetes, brain aging, and cognition
-
S Roriz-Filho J, Sa-Roriz TM, Rosset I, Camozzato AL, Santos AC, et al. (2009) (Pre)diabetes, brain aging, and cognition. Biochim Biophys Acta 1792: 432-443.
-
(2009)
Biochim Biophys Acta
, vol.1792
, pp. 432-443
-
-
Roriz-Filho, S.J.1
Sa-Roriz, T.M.2
Rosset, I.3
Camozzato, A.L.4
Santos, A.C.5
-
37
-
-
29044449855
-
Risk of dementia in diabetes mellitus: A systematic review
-
Biessels GJ, Staekenborg S, Brunner E, Brayne C, Scheltens P, (2006) Risk of dementia in diabetes mellitus: A systematic review. Lancet Neurol 5: 64-74.
-
(2006)
Lancet Neurol
, vol.5
, pp. 64-74
-
-
Biessels, G.J.1
Staekenborg, S.2
Brunner, E.3
Brayne, C.4
Scheltens, P.5
-
38
-
-
1242316296
-
Insulin and neurodegenerative disease: Shared and specific mechanisms
-
Craft S, Watson GS, (2004) Insulin and neurodegenerative disease: Shared and specific mechanisms. Lancet Neurol 3: 169-178.
-
(2004)
Lancet Neurol
, vol.3
, pp. 169-178
-
-
Craft, S.1
Watson, G.S.2
-
39
-
-
45949092783
-
VisANT: An integrative framework for networks in systems biology
-
Hu Z, Snitkin ES, DeLisi C, (2008) VisANT: An integrative framework for networks in systems biology. Brief Bioinform 9: 317-325.
-
(2008)
Brief Bioinform
, vol.9
, pp. 317-325
-
-
Hu, Z.1
Snitkin, E.S.2
de Lisi, C.3
|