메뉴 건너뛰기




Volumn 6, Issue 4, 2011, Pages

Shared molecular and functional frameworks among five complex human disorders: A comparative study on interactomes linked to susceptibility genes

Author keywords

[No Author keywords available]

Indexed keywords

EPIDERMAL GROWTH FACTOR; FIBROBLAST GROWTH FACTOR; GROWTH FACTOR; HLA DQA1 ANTIGEN; INTERLEUKIN 2; INTERLEUKIN 3; PLATELET DERIVED GROWTH FACTOR; PROTEIN TYROSINE KINASE A; PROTEIN TYROSINE PHOSPHATASE SHP 2; SOMATOMEDIN C; SPROUTY PROTEIN; TREFOIL PEPTIDE; TUMOR NECROSIS FACTOR RECEPTOR ASSOCIATED FACTOR 1;

EID: 79955453474     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0018660     Document Type: Article
Times cited : (28)

References (40)
  • 1
    • 77951240586 scopus 로고    scopus 로고
    • Network properties of complex human disease genes identified through genome-wide association studies
    • Barrenas F, Chavali S, Holme P, Mobini R, Benson M, (2009) Network properties of complex human disease genes identified through genome-wide association studies. PLoS One 4: e8090.
    • (2009) PLoS One , vol.4
    • Barrenas, F.1    Chavali, S.2    Holme, P.3    Mobini, R.4    Benson, M.5
  • 2
    • 41949118715 scopus 로고    scopus 로고
    • Network properties of genes harboring inherited disease mutations
    • Feldman I, Rzhetsky A, Vitkup D, (2008) Network properties of genes harboring inherited disease mutations. Proc Natl Acad Sci U S A 105: 4323-4328.
    • (2008) Proc Natl Acad Sci U S A , vol.105 , pp. 4323-4328
    • Feldman, I.1    Rzhetsky, A.2    Vitkup, D.3
  • 3
    • 48249139449 scopus 로고    scopus 로고
    • Multiple sclerosis: An immune or neurodegenerative disorder?
    • Trapp BD, Nave KA, (2008) Multiple sclerosis: An immune or neurodegenerative disorder? Annu Rev Neurosci 31: 247-269.
    • (2008) Annu Rev Neurosci , vol.31 , pp. 247-269
    • Trapp, B.D.1    Nave, K.A.2
  • 4
    • 67249117049 scopus 로고    scopus 로고
    • Potential etiologic and functional implications of genome-wide association loci for human diseases and traits
    • Hindorff LA, Sethupathy P, Junkins HA, Ramos EM, Mehta JP, et al. (2009) Potential etiologic and functional implications of genome-wide association loci for human diseases and traits. Proc Natl Acad Sci U S A 106: 9362-9367.
    • (2009) Proc Natl Acad Sci U S A , vol.106 , pp. 9362-9367
    • Hindorff, L.A.1    Sethupathy, P.2    Junkins, H.A.3    Ramos, E.M.4    Mehta, J.P.5
  • 5
    • 59249097905 scopus 로고    scopus 로고
    • Shared susceptibility variations in autoimmune diseases: A brief perspective on common issues
    • Seldin MF, Amos CI, (2009) Shared susceptibility variations in autoimmune diseases: A brief perspective on common issues. Genes Immun 10: 1-4.
    • (2009) Genes Immun , vol.10 , pp. 1-4
    • Seldin, M.F.1    Amos, C.I.2
  • 7
    • 59149093799 scopus 로고    scopus 로고
    • Variation within the CLEC16A gene shows consistent disease association with both multiple sclerosis and type 1 diabetes in sardinia
    • Zoledziewska M, Costa G, Pitzalis M, Cocco E, Melis C, et al. (2009) Variation within the CLEC16A gene shows consistent disease association with both multiple sclerosis and type 1 diabetes in sardinia. Genes Immun 10: 15-17.
    • (2009) Genes Immun , vol.10 , pp. 15-17
    • Zoledziewska, M.1    Costa, G.2    Pitzalis, M.3    Cocco, E.4    Melis, C.5
  • 8
    • 34548299105 scopus 로고    scopus 로고
    • Risk alleles for multiple sclerosis identified by a genomewide study
    • International Multiple Sclerosis Genetics Consortium
    • Hafler DA, Compston A, Sawcer S, Lander ES, et al. International Multiple Sclerosis Genetics Consortium (2007) Risk alleles for multiple sclerosis identified by a genomewide study. N Engl J Med 357: 851-862.
    • (2007) N Engl J Med , vol.357 , pp. 851-862
    • Hafler, D.A.1    Compston, A.2    Sawcer, S.3    Lander, E.S.4
  • 9
    • 34548367511 scopus 로고    scopus 로고
    • Large-scale genetic fine mapping and genotype-phenotype associations implicate polymorphism in the IL2RA region in type 1 diabetes
    • Lowe CE, Cooper JD, Brusko T, Walker NM, Smyth DJ, et al. (2007) Large-scale genetic fine mapping and genotype-phenotype associations implicate polymorphism in the IL2RA region in type 1 diabetes. Nat Genet 39: 1074-1082.
    • (2007) Nat Genet , vol.39 , pp. 1074-1082
    • Lowe, C.E.1    Cooper, J.D.2    Brusko, T.3    Walker, N.M.4    Smyth, D.J.5
  • 10
    • 70449470314 scopus 로고    scopus 로고
    • The genetics of autoimmune diseases: A networked perspective
    • Baranzini SE, (2009) The genetics of autoimmune diseases: A networked perspective. Curr Opin Immunol 21: 596-605.
    • (2009) Curr Opin Immunol , vol.21 , pp. 596-605
    • Baranzini, S.E.1
  • 11
    • 60549085927 scopus 로고    scopus 로고
    • Gene-wide analyses of genome-wide association data sets: Evidence for multiple common risk alleles for schizophrenia and bipolar disorder and for overlap in genetic risk
    • Moskvina V, Craddock N, Holmans P, Nikolov I, Pahwa JS, et al. (2009) Gene-wide analyses of genome-wide association data sets: Evidence for multiple common risk alleles for schizophrenia and bipolar disorder and for overlap in genetic risk. Mol Psychiatry 14: 252-260.
    • (2009) Mol Psychiatry , vol.14 , pp. 252-260
    • Moskvina, V.1    Craddock, N.2    Holmans, P.3    Nikolov, I.4    Pahwa, J.S.5
  • 12
    • 32244434299 scopus 로고    scopus 로고
    • Comprehensive analysis of pathway or functionally related gene expression in the national cancer institute's anticancer screen
    • Huang R, Wallqvist A, Covell DG, (2006) Comprehensive analysis of pathway or functionally related gene expression in the national cancer institute's anticancer screen. Genomics 87: 315-328.
    • (2006) Genomics , vol.87 , pp. 315-328
    • Huang, R.1    Wallqvist, A.2    Covell, D.G.3
  • 13
    • 77950339092 scopus 로고    scopus 로고
    • Integrating pathway analysis and genetics of gene expression for genome-wide association studies
    • Zhong H, Yang X, Kaplan LM, Molony C, Schadt EE, (2010) Integrating pathway analysis and genetics of gene expression for genome-wide association studies. Am J Hum Genet 86: 581-591.
    • (2010) Am J Hum Genet , vol.86 , pp. 581-591
    • Zhong, H.1    Yang, X.2    Kaplan, L.M.3    Molony, C.4    Schadt, E.E.5
  • 14
    • 84864288185 scopus 로고    scopus 로고
    • A pathway-based view of human diseases and disease relationships
    • Li Y, Agarwal P, (2009) A pathway-based view of human diseases and disease relationships. PLoS One 4: e4346.
    • (2009) PLoS One , vol.4
    • Li, Y.1    Agarwal, P.2
  • 15
    • 65549084289 scopus 로고    scopus 로고
    • Pathway and network-based analysis of genome-wide association studies in multiple sclerosis
    • Baranzini SE, Galwey NW, Wang J, Khankhanian P, Lindberg R, et al. (2009) Pathway and network-based analysis of genome-wide association studies in multiple sclerosis. Hum Mol Genet 18: 2078-2090.
    • (2009) Hum Mol Genet , vol.18 , pp. 2078-2090
    • Baranzini, S.E.1    Galwey, N.W.2    Wang, J.3    Khankhanian, P.4    Lindberg, R.5
  • 17
    • 0029811901 scopus 로고    scopus 로고
    • Arthritis and anti-inflammatory agents as possible protective factors for alzheimer's disease: A review of 17 epidemiologic studies
    • McGeer PL, Schulzer M, McGeer EG, (1996) Arthritis and anti-inflammatory agents as possible protective factors for alzheimer's disease: A review of 17 epidemiologic studies. Neurology 47: 425-432.
    • (1996) Neurology , vol.47 , pp. 425-432
    • McGeer, P.L.1    Schulzer, M.2    McGeer, E.G.3
  • 18
    • 43149102747 scopus 로고    scopus 로고
    • Protective effects of NSAIDs on the development of alzheimer disease
    • Vlad SC, Miller DR, Kowall NW, Felson DT, (2008) Protective effects of NSAIDs on the development of alzheimer disease. Neurology 70: 1672-1677.
    • (2008) Neurology , vol.70 , pp. 1672-1677
    • Vlad, S.C.1    Miller, D.R.2    Kowall, N.W.3    Felson, D.T.4
  • 19
    • 33747890559 scopus 로고    scopus 로고
    • The brain as a target of inflammation: Common pathways link inflammatory and neurodegenerative diseases
    • Zipp F, Aktas O, (2006) The brain as a target of inflammation: Common pathways link inflammatory and neurodegenerative diseases. Trends Neurosci 29: 518-527.
    • (2006) Trends Neurosci , vol.29 , pp. 518-527
    • Zipp, F.1    Aktas, O.2
  • 20
    • 77952322955 scopus 로고    scopus 로고
    • Loss of epidermal growth factor regulation by cobalamin in multiple sclerosis
    • Scalabrino G, Galimberti D, Mutti E, Scalabrini D, Veber D, et al. (2010) Loss of epidermal growth factor regulation by cobalamin in multiple sclerosis. Brain Res 1333: 64-71.
    • (2010) Brain Res , vol.1333 , pp. 64-71
    • Scalabrino, G.1    Galimberti, D.2    Mutti, E.3    Scalabrini, D.4    Veber, D.5
  • 21
    • 77949883177 scopus 로고    scopus 로고
    • Epidermal growth factor increases prostaglandin E2 production via ERK1/2 MAPK and NF-kappaB pathway in fibroblast like synoviocytes from patients with rheumatoid arthritis
    • Nah SS, Won HJ, Ha E, Kang I, Cho HY, et al. (2010) Epidermal growth factor increases prostaglandin E2 production via ERK1/2 MAPK and NF-kappaB pathway in fibroblast like synoviocytes from patients with rheumatoid arthritis. Rheumatol Int 30: 443-449.
    • (2010) Rheumatol Int , vol.30 , pp. 443-449
    • Nah, S.S.1    Won, H.J.2    Ha, E.3    Kang, I.4    Cho, H.Y.5
  • 22
    • 0024466345 scopus 로고
    • Nerve and epidermal growth factors induce the release of the alzheimer amyloid precursor from PC 12 cell cultures
    • Refolo LM, Salton SR, Anderson JP, Mehta P, Robakis NK, (1989) Nerve and epidermal growth factors induce the release of the alzheimer amyloid precursor from PC 12 cell cultures. Biochem Biophys Res Commun 164: 664-670.
    • (1989) Biochem Biophys Res Commun , vol.164 , pp. 664-670
    • Refolo, L.M.1    Salton, S.R.2    Anderson, J.P.3    Mehta, P.4    Robakis, N.K.5
  • 23
    • 33845534764 scopus 로고    scopus 로고
    • Downregulation of EGF receptor signaling in pancreatic islets causes diabetes due to impaired postnatal beta-cell growth
    • Miettinen PJ, Ustinov J, Ormio P, Gao R, Palgi J, et al. (2006) Downregulation of EGF receptor signaling in pancreatic islets causes diabetes due to impaired postnatal beta-cell growth. Diabetes 55: 3299-3308.
    • (2006) Diabetes , vol.55 , pp. 3299-3308
    • Miettinen, P.J.1    Ustinov, J.2    Ormio, P.3    Gao, R.4    Palgi, J.5
  • 24
    • 0034649608 scopus 로고    scopus 로고
    • Attenuation of FGF signalling in mouse beta-cells leads to diabetes
    • Hart AW, Baeza N, Apelqvist A, Edlund H, (2000) Attenuation of FGF signalling in mouse beta-cells leads to diabetes. Nature 408: 864-868.
    • (2000) Nature , vol.408 , pp. 864-868
    • Hart, A.W.1    Baeza, N.2    Apelqvist, A.3    Edlund, H.4
  • 25
    • 77949912530 scopus 로고    scopus 로고
    • Expression of insulin-like growth factor-1 and insulin-like growth factor binding proteins in the serum and cerebrospinal fluid of patients with parkinson's disease
    • Mashayekhi F, Mirzajani E, Naji M, Azari M, (2010) Expression of insulin-like growth factor-1 and insulin-like growth factor binding proteins in the serum and cerebrospinal fluid of patients with parkinson's disease. J Clin Neurosci 17: 623-627.
    • (2010) J Clin Neurosci , vol.17 , pp. 623-627
    • Mashayekhi, F.1    Mirzajani, E.2    Naji, M.3    Azari, M.4
  • 26
    • 67149139990 scopus 로고    scopus 로고
    • The role of IGF-1 receptor and insulin receptor signaling for the pathogenesis of alzheimer's disease: From model organisms to human disease
    • Freude S, Schilbach K, Schubert M, (2009) The role of IGF-1 receptor and insulin receptor signaling for the pathogenesis of alzheimer's disease: From model organisms to human disease. Curr Alzheimer Res 6: 213-223.
    • (2009) Curr Alzheimer Res , vol.6 , pp. 213-223
    • Freude, S.1    Schilbach, K.2    Schubert, M.3
  • 27
    • 71949112504 scopus 로고    scopus 로고
    • Increased tau phosphorylation and cleavage in mouse models of type 1 and type 2 diabetes
    • Kim B, Backus C, Oh S, Hayes JM, Feldman EL, (2009) Increased tau phosphorylation and cleavage in mouse models of type 1 and type 2 diabetes. Endocrinology 150: 5294-5301.
    • (2009) Endocrinology , vol.150 , pp. 5294-5301
    • Kim, B.1    Backus, C.2    Oh, S.3    Hayes, J.M.4    Feldman, E.L.5
  • 28
    • 77952585217 scopus 로고    scopus 로고
    • Type 1 diabetes exaggerates features of alzheimer's disease in APP transgenic mice
    • Jolivalt CG, Hurford R, Lee CA, Dumaop W, Rockenstein E, et al. (2010) Type 1 diabetes exaggerates features of alzheimer's disease in APP transgenic mice. Exp Neurol 223: 422-431.
    • (2010) Exp Neurol , vol.223 , pp. 422-431
    • Jolivalt, C.G.1    Hurford, R.2    Lee, C.A.3    Dumaop, W.4    Rockenstein, E.5
  • 29
    • 67649729196 scopus 로고    scopus 로고
    • Vascular factors in diabetes and alzheimer's disease
    • Taguchi A, (2009) Vascular factors in diabetes and alzheimer's disease. J Alzheimers Dis 16: 859-864.
    • (2009) J Alzheimers Dis , vol.16 , pp. 859-864
    • Taguchi, A.1
  • 30
    • 0026074976 scopus 로고
    • Intrathecal immune response in patients with the post-polio syndrome
    • Sharief MK, Hentges R, Ciardi M, (1991) Intrathecal immune response in patients with the post-polio syndrome. N Engl J Med 325: 749-755.
    • (1991) N Engl J Med , vol.325 , pp. 749-755
    • Sharief, M.K.1    Hentges, R.2    Ciardi, M.3
  • 31
    • 0032704934 scopus 로고    scopus 로고
    • The function of tumour necrosis factor and receptors in models of multi-organ inflammation, rheumatoid arthritis, multiple sclerosis and inflammatory bowel disease
    • Kollias G, Douni E, Kassiotis G, Kontoyiannis D, (1999) The function of tumour necrosis factor and receptors in models of multi-organ inflammation, rheumatoid arthritis, multiple sclerosis and inflammatory bowel disease. Ann Rheum Dis 58 (Suppl 1): I32-9.
    • (1999) Ann Rheum Dis , vol.58 , Issue.SUPPL. 1
    • Kollias, G.1    Douni, E.2    Kassiotis, G.3    Kontoyiannis, D.4
  • 32
    • 62849115074 scopus 로고    scopus 로고
    • How do the efficacy and safety of abatacept and infliximab compare in the treatment of active RA?
    • Taylor PC, (2009) How do the efficacy and safety of abatacept and infliximab compare in the treatment of active RA? Nat Clin Pract Rheumatol 5: 126-127.
    • (2009) Nat Clin Pract Rheumatol , vol.5 , pp. 126-127
    • Taylor, P.C.1
  • 33
    • 0033546665 scopus 로고    scopus 로고
    • TNF neutralization in MS: Results of a randomized, placebo-controlled multicenter study. the lenercept multiple sclerosis study group and the university of british columbia MS/MRI analysis group
    • (1999) TNF neutralization in MS: Results of a randomized, placebo-controlled multicenter study. the lenercept multiple sclerosis study group and the university of british columbia MS/MRI analysis group. Neurology 53: 457-465.
    • (1999) Neurology , vol.53 , pp. 457-465
  • 34
    • 0032734010 scopus 로고    scopus 로고
    • Apoptotic and effector pathways in autoimmunity
    • Chervonsky AV, (1999) Apoptotic and effector pathways in autoimmunity. Curr Opin Immunol 11: 684-688.
    • (1999) Curr Opin Immunol , vol.11 , pp. 684-688
    • Chervonsky, A.V.1
  • 35
    • 34548306413 scopus 로고    scopus 로고
    • Apoptotic signal transduction and T cell tolerance
    • Gatzka M, Walsh CM, (2007) Apoptotic signal transduction and T cell tolerance. Autoimmunity 40: 442-452.
    • (2007) Autoimmunity , vol.40 , pp. 442-452
    • Gatzka, M.1    Walsh, C.M.2
  • 38
    • 1242316296 scopus 로고    scopus 로고
    • Insulin and neurodegenerative disease: Shared and specific mechanisms
    • Craft S, Watson GS, (2004) Insulin and neurodegenerative disease: Shared and specific mechanisms. Lancet Neurol 3: 169-178.
    • (2004) Lancet Neurol , vol.3 , pp. 169-178
    • Craft, S.1    Watson, G.S.2
  • 39
    • 45949092783 scopus 로고    scopus 로고
    • VisANT: An integrative framework for networks in systems biology
    • Hu Z, Snitkin ES, DeLisi C, (2008) VisANT: An integrative framework for networks in systems biology. Brief Bioinform 9: 317-325.
    • (2008) Brief Bioinform , vol.9 , pp. 317-325
    • Hu, Z.1    Snitkin, E.S.2    de Lisi, C.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.