Epidermal growth factor increases prostaglandin E2 production via ERK1/2 MAPK and NF-icB pathway in fibroblast like synoviocytes from patients with rheumatoid arthritis

Rheumatology International

Volumn 30, Issue 4, 2010, Pages 443-449

  Nah, Seong Su ^b   Won, Hye Jin ^d   Ha, Eunyoung ^a   Kang, Insug ^a   Cho, Hong Yon ^c   Hur, Sook Jin ^d   Lee, Sang Hoon ^a   Baik, Hyung Hwan ^a  

^a Kyung Hee University Hospital   (South Korea)

^b Soonchunhyang University   (South Korea)

^c Korea University   (South Korea)

^d Korea Food and Drug Administration   (South Korea)

Author keywords

Cyclooxygenase 2; Epidermal growth factor; Mitogen activated protein kinase; Prostaglandin E2; Rheumatoid arthritis

Indexed keywords

CYCLOOXYGENASE 2; EPIDERMAL GROWTH FACTOR; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; MESSENGER RNA; METHOTREXATE; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; NONSTEROID ANTIINFLAMMATORY AGENT; PREDNISOLONE; PROSTAGLANDIN E SYNTHASE 1; PROSTAGLANDIN E2; SALAZOSULFAPYRIDINE; DNA BINDING PROTEIN; ISOMERASE; PROSTAGLANDIN E SYNTHASE; PTGS2 PROTEIN, HUMAN;

AGED; ARTICLE; CLINICAL ARTICLE; CONTROLLED STUDY; ENZYME ACTIVITY; ENZYME INHIBITION; GENE EXPRESSION; HUMAN; HUMAN CELL; HUMAN TISSUE; INFLAMMATION; PRIORITY JOURNAL; PROSTAGLANDIN SYNTHESIS; PROTEIN DNA BINDING; PROTEIN EXPRESSION; RHEUMATOID ARTHRITIS; SIGNAL TRANSDUCTION; SYNOVIOCYTE; TOTAL KNEE REPLACEMENT; DRUG EFFECT; ENZYMOLOGY; FIBROBLAST; GENETICS; METABOLISM; MICROSOME; PATHOLOGY; SYNOVIUM; UPREGULATION;

ARTHRITIS, RHEUMATOID; CYCLOOXYGENASE 2; DINOPROSTONE; DNA-BINDING PROTEINS; EPIDERMAL GROWTH FACTOR; FIBROBLASTS; HUMANS; INTRAMOLECULAR OXIDOREDUCTASES; MICROSOMES; MITOGEN-ACTIVATED PROTEIN KINASE 1; MITOGEN-ACTIVATED PROTEIN KINASE 3; NF-KAPPA B; RNA, MESSENGER; SYNOVIAL MEMBRANE; UP-REGULATION;

EID: 77949883177     PISSN: 01728172     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00296-009-0976-6     Document Type: Article

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