Theonellasterols and conicasterols from Theonella swinhoei. Novel marine natural ligands for human nuclear receptors

Journal of Medicinal Chemistry

Volumn 54, Issue 8, 2011, Pages 3065-3075

  De Marino, Simona ^a   Ummarino, Raffaella ^a   D'Auria, Maria Valeria ^a   Chini, Maria Giovanna ^b   Bifulco, Giuseppe ^b   Renga, Barbara ^c   D'Amore, Claudio ^c   Fiorucci, Stefano ^c   Debitus, Cécile ^d   Zampella, Angela ^a  

^a UNIVERSITY OF NAPLES FEDERICO II   (Italy)

^b UNIVERSITY OF SALERNO   (Italy)

^c UNIVERSITY OF PERUGIA   (Italy)

^d Polynesian Research Center on Island Biodiversity   (French Polynesia)

Author keywords

[No Author keywords available]

Indexed keywords

CELL NUCLEUS RECEPTOR; CONICASTEROL B; CONICASTEROL C; CONICASTEROL D; CONICASTEROL DERIVATIVE; FARNESOID X RECEPTOR; LIGAND; NATURAL PRODUCT; PREGNANE X RECEPTOR; SILICA GEL; STEROID; THEONELLASTEROL B; THEONELLASTEROL C; THEONELLASTEROL D; THEONELLASTEROL DERIVATIVE; THEONELLASTEROL E; THEONELLASTEROL F; THEONELLASTEROL G; THEONELLASTEROL H; UNCLASSIFIED DRUG;

ANALYTIC METHOD; ARTICLE; CARBON NUCLEAR MAGNETIC RESONANCE; COLUMN CHROMATOGRAPHY; CORRELATION SPECTROSCOPY; DRUG ISOLATION; DRUG POTENCY; DRUG RECEPTOR BINDING; GENE INDUCTION; HETERONUCLEAR MULTIPLE BOND CORRELATION; HETERONUCLEAR SINGLE QUANTUM COHERENCE; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HUMAN; HUMAN CELL; MASS SPECTROMETRY; MOLECULAR DOCKING; NONHUMAN; PROTON NUCLEAR MAGNETIC RESONANCE; ROTATING FRAME NUCLEAR OVERHAUS EFFECT SPECTROSCOPY; STRUCTURE ACTIVITY RELATION; THEONELLA; THEONELLA SWINHOEI;

ANIMALS; CELL LINE; HUMANS; LIGANDS; MAGNETIC RESONANCE SPECTROSCOPY; MARINE BIOLOGY; MODELS, MOLECULAR; RECEPTORS, CYTOPLASMIC AND NUCLEAR; RECEPTORS, STEROID; SPECTROMETRY, MASS, ELECTROSPRAY IONIZATION; STEROLS; THEONELLA;

EID: 79955443595     PISSN: 00222623     EISSN: 15204804     Source Type: Journal    
DOI: 10.1021/jm200169t     Document Type: Article

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