A model for random genetic damage directing selection of diploid or aneuploid tumours

Cell Proliferation

Volumn 44, Issue 3, 2011, Pages 212-223

  Bazeley, P S ^a   Nestor Kalinoski, A L ^b   Ways, J A ^b   Liu, S T ^a   Ramdath, R S ^b   Matsui, S I ^c   Allison, D C ^b  

^a UNIVERSITY OF TOLEDO   (United States)

^b MEDICAL COLLEGE OF OHIO   (United States)

^c ROSWELL PARK CANCER INSTITUTE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANEUPLOIDY; ARTICLE; CANCER CELL CULTURE; CANCER STEM CELL; CELL DIVISION; CELL PROLIFERATION; CELL SURVIVAL; CELL TYPE; CHROMOSOME ABERRATION; COMPUTER MODEL; CONTROLLED STUDY; DIPLOIDY; GENE EXPRESSION; GENE INACTIVATION; GENE LOSS; GENE MUTATION; GENETIC DAMAGE; GENETIC DATABASE; GENOME; HETEROZYGOSITY; HUMAN; HUMAN CELL; HUMAN TISSUE; MISMATCH REPAIR; SINGLE NUCLEOTIDE POLYMORPHISM;

ALLELES; ANEUPLOIDY; CELL LINE, TUMOR; CELL SURVIVAL; CHROMOSOMAL INSTABILITY; CHROMOSOME ABERRATIONS; CHROMOSOMES; DIPLOIDY; GENE EXPRESSION PROFILING; GENE EXPRESSION REGULATION, NEOPLASTIC; HUMANS; LOSS OF HETEROZYGOSITY; MALE; MODELS, BIOLOGICAL; MODELS, GENETIC; MUTATION; NEOPLASMS; OLIGONUCLEOTIDE ARRAY SEQUENCE ANALYSIS; STEM CELLS;

EID: 79955441797     PISSN: 09607722     EISSN: 13652184     Source Type: Journal    
DOI: 10.1111/j.1365-2184.2011.00746.x     Document Type: Article

References (50)

1. Albertson DG, Collins C, McCormick F, Gray JW (2003) Chromosome aberrations in solid tumors. Nat. Genet. 34, 369-376.
2. Torres EM, Williams BR, Amon A (2008) Aneuploidy: cells losing their balance. Genetics 179, 737-746.
3. Komarova NL, Lengauer C, Vogelstein B, Nowak MA (2002) Dynamics of genetic instability in sporadic and familial colorectal cancer. Cancer Biol. Ther. 1, 685-692.
4. Lengauer C, Kinzler KW, Vogelstein B (1998) Genetic instabilities in human cancers. Nature 396, 643-649.
5. Brothman AR, Persons DL, Shaffer LG (2009) Nomenclature evolution: changes in the ISCN from the 2005 to the 2009 Edition. Cytogenet. Genome Res. 127, 1-4.
6. Bignell GR, Greenman CD, Davies H, Butler AP, Edkins S, Andrews JM et al. (2010) Signatures of mutation and selection in the cancer genome. Nature 463, 893-898.
7. Johansson B, Mertens F, Mitelman F (1996) Primary vs. secondary neoplasia-associated chromosomal abnormalities - balanced rearrangements vs. genomic imbalances? Genes Chromosomes Cancer 16, 155-163.
8. Ganem NJ, Storchova Z, Pellman D (2007) Tetraploidy, aneuploidy and cancer. Curr. Opin. Genet. Dev. 17, 157-162.
9. Holland AJ, Cleveland DW (2009) Boveri revisited: chromosomal instability, aneuploidy and tumorigenesis. Nat. Rev. Mol. Cell Biol. 10, 478-487.
10. Storchova Z, Kuffer C (2008) The consequences of tetraploidy and aneuploidy. J. Cell Sci. 121, 3859-3866.
11. Bartek J, Bartkova J, Lukas J (2007) DNA damage signalling guards against activated oncogenes and tumour progression. Oncogene 26, 7773-7779.
12. Paulovich AG, Toczyski DP, Hartwell LH (1997) When checkpoints fail. Cell 88, 315-321.
13. Merel P, Prieur A, Pfeiffer P, Delattre O (2002) Absence of major defects in non-homologous DNA end joining in human breast cancer cell lines. Oncogene 21, 5654-5659.
14. Cahill DP, Lengauer C, Yu J, Riggins GJ, Willson JK, Markowitz SD et al. (1998) Mutations of mitotic checkpoint genes in human cancers. Nature 392, 300-303.
15. Nestor AL, Hollopeter SL, Matsui SI, Allison D (2007) A model for genetic complementation controlling the chromosomal abnormalities and loss of heterozygosity formation in cancer. Cytogenet Genome Res. 116, 235-247.
16. Seo J, Bakay M, Chen Y-W, Hilmer S, Shneiderman B, Hoffman EP (2004) Interactively optimizing signal-to-noise ratios in expression profiling: project-specific algorithm selection and detection p-value weighting in Affymetrix microarrays. Bioinformatics 20, 2534-2544.
17. Su AI, Wiltshire T, Batalov S, Lapp H, Ching KA, Block D et al. (2004) A gene atlas of the mouse and human protein-encoding transcriptomes. Proc. Natl. Acad. Sci. USA 101, 6062-6067.
18. Dezso Z, Nikolsky Y, Sviridov E, Shi W, Serebriyskaya T, Dosymbekov D et al. (2008) A comprehensive functional analysis of tissue specificity of human gene expression. BMC Biol. 6, 49.
19. Eisenberg E, Levanon EY (2003) Human housekeeping genes are compact. Trends Genet. 19, 362-365.
20. Hsiao L-L, Dangond F, Yoshida T, Hong R, Jensen RV, Misra J et al. (2001) A compendium of gene expression in normal human tissues. Physiol. Genomics 7, 97-104.
21. Tu Z, Wang L, Xu M, Zhou X, Chen T, Sun F (2006) Further understanding human disease genes by comparing with housekeeping genes and other genes. BMC Genomics 7, 31.
22. Warrington JA, Nair A, Mahadevappa M, Tsyganskaya M (2000) Comparison of human adult and fetal expression and identification of 535 housekeeping/maintenance genes. Physiol. Genomics 2, 143-147.
23. Ertel A, Verghese A, Byers S, Ochs M, Tozeren A (2006) Pathway-specific differences between tumor cell lines and normal and tumor tissue cells. Mol. Cancer 5, 55.
24. van Staveren WCG, Solís DYW, Hébrant A, Detours V, Dumont JE, Maenhaut C (2009) Human cancer cell lines: experimental models for cancer cells in situ? For cancer stem cells? Biochim. Biophys. Acta 1795, 92-103.
25. Baltzer F (1967) The Chromosome Theory of Inheritance, Experiments with Doubly Fertilized Sea Urchin Eggs (Dispermy Experiments). Theodor Boveri, Life and Work of a Great Biologist, 1862-1915. Berkeley and Los Angeles: University of California Press, pp. 85-97.
26. Araten DJ, Golde DW, Zhang RH, Thaler HT, Gargiulo L, Notaro R et al. (2005) A quantitative measurement of the human somatic mutation rate. Cancer Res. 65, 8111-8117.
27. Salk JJ, Fox EJ, Loeb LA (2010) Mutational heterogeneity in human cancers: origin and consequences. Annu. Rev. Pathol. Mech. Dis. 5, 51-75.
28. Abdel-Rahman WM (2008) Genomic instability and carcinogenesis: an update. Curr. Genomics 9, 535-541.
29. Eshleman JR, Markowitz SD, Donover PS, Lang EZ, Lutterbaugh JD, Li GM et al. (1996) Diverse hypermutability of multiple expressed sequence motifs present in a cancer with microsatellite instability. Oncogene 12, 1425-1432.
30. Toft NJ, Arends MJ (1998) DNA mismatch repair and colorectal cancer. J. Pathol. 185, 123-129.
31. Yatabe Y, Tavaré S, Shibata D (2001) Investigating stem cells in human colon by using methylation patterns. Proc. Natl. Acad. Sci. USA 98, 10839-10844.
32. Bach SP, Renehan AG, Potten CS (2000) Stem cells: the intestinal stem cell as a paradigm. Carcinogenesis 21, 469-476.
33. Pleasance ED, Cheetham RK, Stephens PJ, McBride DJ, Humphray SJ, Greenman CD et al. (2010) A comprehensive catalogue of somatic mutations from a human cancer genome. Nature 463, 191-196.
34. Stratton MR, Campbell PJ, Futreal PA (2009) The cancer genome. Nature 458, 719-724.
35. Tomlinson I, Sasieni P, Bodmer W (2002) How many mutations in a cancer? Am. J. Pathol. 160, 755-758.
36. Greenman C, Stephens P, Smith R, Dalgliesh GL, Hunter C, Bignell G et al. (2007) Patterns of somatic mutation in human cancer genomes. Nature 446, 153-158.
37. Baudis M (2007) Genomic imbalances in 5918 malignant epithelial tumors: an explorative meta-analysis of chromosomal CGH data. BMC Cancer 7, 226.
38. Beroukhim R, Mermel CH, Porter D, Wei G, Raychaudhuri S, Donovan J et al. (2010) The landscape of somatic copy-number alteration across human cancers. Nature 463, 899-905.
39. Cervantes RB, Stringer JR, Shao C, Tischfield JA, Stambrook PJ (2002) Embryonic stem cells and somatic cells differ in mutation frequency and type. Proc. Natl. Acad. Sci. USA 99, 3586-3590.
40. Rusan NM, Peifer M (2008) Original CIN: reviewing roles for APC in chromosome instability. J. Cell Biol. 181, 719-726.
41. Fujiwara T, Bandi M, Nitta M, Ivanova EV, Bronson RT, Pellman D (2005) Cytokinesis failure generating tetraploids promotes tumorigenesis in p53-null cells. Nature 437, 1043-1047.
42. Rao CV, Yamada HY, Yao Y, Dai W (2009) Enhanced genomic instabilities caused by deregulated microtubule dynamics and chromosome segregation: a perspective from genetic studies in mice. Carcinogenesis 30, 1469-1474.
43. Sugai T, Habano W, Nakamura S-I, Sato H, Uesugi N, Takahashi H et al. (2000) Genetic alterations in DNA diploid, aneuploid and multiploid colorectal carcinomas identified by the crypt isolation technique. Int. J. Cancer 88, 614-619.
44. Peltomaki P (2001) Deficient DNA mismatch repair: a common etiologic factor for colon cancer. Hum. Mol. Genet. 10, 735-740.
45. Steel GG (1977) Growth Kinetics of Tumours: Cell Population Kinetics in Relation to the Growth and Treatment of Cancer. Oxford: Clarendon Press, p. 191.
46. Murchison EP (2009) Clonally transmissible cancers in dogs and Tasmanian devils. Oncogene 27(S2), S19-S30.
47. Anderson GR, Brenner BM, Swede H, Chen N, Henry WM, Conroy JM et al. (2001) Intrachromosomal genomic instability in human sporadic colorectal cancer measured by genome-wide allelotyping and inter-(simple sequence repeat) PCR. Cancer Res. 61, 8274-8283.
48. Stephens PJ, McBride DJ, Lin M-L, Varela I, Pleasance ED, Simpson JT et al. (2009) Complex landscapes of somatic rearrangement in human breast cancer genomes. Nature 462, 1005-1010.
49. Birchler JA, Yao H, Chudalayandi S (2007) Biological consequences of dosage dependent gene regulatory systems. Biochim. Biophys. Acta 1769, 422-428.
50. Torres EM, Dephoure N, Panneerselvam A, Tucker CM, Whittaker CA, Gygi SP et al. (2010) Identification of aneuploidy-tolerating mutations. Cell 143, 71-83.