Biomechanics of leukocyte rolling

Biorheology

Volumn 48, Issue 1, 2011, Pages 1-35

  Sundd, Prithu ^a   Pospieszalska, Maria K ^a   Cheung, Luthur Siu Lun ^b   Konstantopoulos, Konstantinos ^b   Ley, Klaus ^a  

^a LA JOLLA INSTITUTE FOR ALLERGY AND IMMUNOLOGY   (United States)

^b Johns Hopkins University   (United States)

Author keywords

event tracking model of adhesion; footprint; immersed boundary method; P selectin; Quantitative dynamic footprinting

Indexed keywords

ENDOTHELIAL LEUKOCYTE ADHESION MOLECULE 1; L SELECTIN; P SELECTIN GLYCOPROTEIN LIGAND 1; PADGEM PROTEIN;

BIOMECHANICS; COMPUTER MODEL; CONFORMATION; DISSOCIATION; ENDOTHELIUM CELL; HUMAN; HYDRODYNAMICS; LEUKOCYTE ROLLING; MICROSCOPY; MICROVILLUS; NONHUMAN; PROTEIN BINDING; QUANTITATIVE ANALYSIS; REVIEW; SHEAR STRESS; TORQUE; WHOLE CELL;

ANIMALS; BIOMECHANICS; CELL ADHESION MOLECULES; HUMANS; LEUKOCYTE ROLLING; MECHANICAL PROCESSES; NEUTROPHILS;

EID: 79955427825     PISSN: 0006355X     EISSN: 18785034     Source Type: Journal    
DOI: 10.3233/BIR-2011-0579     Document Type: Review

References (230)

1. W. Addison, Experimental and practical researches on the structure and function of blood corpuscles; on inflammation, and on the origin and nature of tubercules in the lungs, Trans. Provinc. Med. Surg. Ass. 11 (1843), 223-306.
2. V. Afshar-Kharghan, R. Diz-Kucukkaya, E.H. Ludwig et al., Human polymorphism of P-selectin glycoprotein ligand 1 attributable to variable numbers oftandem decameric repeats in the mucinlike region, Blood 97 (2001), 3306-3307.
3. B. Alberts, D. Bray, J. Lewis et al., Molecular Biology ofthe Cell, Garland, New York, 1994.
4. R. Alon, S. Chen, R. Fuhlbrigge et al., The kinetics and shear threshold of transient and rolling interactions of L-selectin with its ligand on leukocytes, Proc. Natl. Acad. Sci. USA 95 (1998), 11631-11636. (Pubitemid 28460466)
5. R. Alon, S. Chen, K.D. Puri et al., The kinetics of L-selectin tethers and the mechanics of selectin-mediated rolling, J. Cell Biol. 138(1997), 1169-1180. (Pubitemid 27386465)
6. R. Alon, R.C. Fuhlbrigge, E.B. Finger and T.A. Springer, Interactions through L-selectin between leukocytes and adherent leukocytes nucleate rolling adhesions on selectins and VCAM-1 in shear flow, J. Cell Biol. 135 (1996), 849-865. (Pubitemid 26372938)
7. R. Alon, D.A. Hammer and T.A. Springer, Lifetime of the P-selectin-carbohydrate bond and its response to tensile force in hydrodynamic flow, Nature 374 (1995), 539-542.
8. M.L. Arbones, D.C. Ord, K. Ley et al., Lymphocyte homing and leukocyte rolling and migration are impaired in L-selectin-deficient mice, Immunity 1 (1994), 247-260.
9. N.S. Astrof, A. Salas, M. Shimaoka et al., Importance of force linkage in mechanochemistry of adhesion receptors, Biochemistry 45 (2006), 15020-15028. (Pubitemid 44937014)
10. A. Atherton and G.V.R. Born, Quantitative investigation ofthe adhesiveness ofcirculating polymorphonuclear leucocytes to blood vessel walls, J. Physiol. 222 (1972), 447-474.
11. A. Atherton and G.V.R. Born, Relationship between the velocity of rolling granulocytes and that of the blood flow in venules, J. Physiol. 233 (1973), 157-165.
12. B. Baisse, F. Galisson, S. Giraud et al., Evolutionary conservation of P-selectin glycoprotein ligand-1 primary structure and function, BMC Evol. Biol. 7 (2007), 166.
13. R.F. Bargatze, S. Kurk, E.C. Butcher and M.A. Jutila, Neutrophils roll on adherent neutrophils bound to cytokine-induced endothelial cells via L-selectin on the rolling cells, J. Exp. Med. 180 (1994), 1785-1792. (Pubitemid 24328569)
14. FJ. Barkalow, K.L. Barkalow and T.N. Mayadas, Dimerization of P-selectin in platelets and endothelial cells, Blood 96 (2000), 3070-3077.
15. G.I. Bell, Models for the specific adhesion of cells to cells, Science 200 (1978), 618-627.
16. N. Borghi and F. Brochard-Wyart, Tether extrusion from red blood cells: integral proteins unbinding from cytoskeleton, J. Physiol. 93 (2007), 1369-1379. (Pubitemid 47330917)
17. F. Brochard-Wyart, N. Borghi, D. Cuvelier and P. Nassoy, Hydrodynamic narrowing of tubes extruded from cells, Proc. Natl. Acad. Sci. USA 103 (2006), 7660-7663.
18. D.C. Bullard, EJ. Kunkel, H. Kubo et al., Infectious susceptibility and severe deficiency of leukocyte rolling and recruitment in E-selectin and P-selectin double mutantmice, J. Exp. Med. 183 (1996), 2329-2336. (Pubitemid 26158923)
19. D.C. Bullard, L. Qin, I. Lorenzo et al., P-selectin/ICAM-1 double mutant mice: acute emigration of neutrophils into the peritoneum is completely absent but is normal into pulmonary alveoli, J. Clin. Invest. 95 (1995), 1782-1788.
20. A. Burns, R. Bowden, Y. Abe et al., P-selectin mediates neutrophil adhesion to endothelial cell borders, J. Leukoc. Biol. 65 (1999), 299-306. (Pubitemid 29109700)
21. E.C. Butcher, Leukocyte-endothelial cell recognition: three (or more) steps to specificity and diversity, Cell 67 (1991), 1033-1036. (Pubitemid 121001517)
22. K.E. Caputo and D.A. Hammer, Effect of microvillus deformability on leukocyte adhesion explored using adhesive dynamics simulations, Biophys. J. 89 (2005), 187-200. (Pubitemid 41098275)
23. K.E. Caputo, D. Lee, M.R. King and D.A. Hammer, Adhesive dynamics simulations of the shear threshold effect for leukocytes, Biophys. J. 92 (2007), 787-797. (Pubitemid 46203209)
24. D.A. Carlow, K. Gossens, S. Naus et al., PSGL-1 function in immunity and steady state homeostasis, Immunol. Rev. 230 (2009), 75-96.
25. K.C. Chang and D.A. Hammer, The forward rate of binding of surface-tethered reactants: effect of relative motion between two surfaces, Biophys. J. 76 (1999), 1280-1292. (Pubitemid 29262610)
26. K.C. Chang, D.FJ. Tees and D.A. Hammer, The state diagram for cell adhesion under flow: leukocyte rolling and firm adhesion, Proc. Natl. Acad. Sci. USA 97 (2000), 11262-11267.
27. S. Chen and T.A. Springer, An automatic braking system that stabilizes leukocyte rolling by an increase in selectin bond number with shear, J. Cell Biol. 144 (1999), 185-200. (Pubitemid 29047021)
28. S. Chen and T.A. Springer, Selectin receptor-ligand bonds: formation limited by shear rate and dissociation governed by the Bell model, Proc. Natl. Acad. Sci. USA 98 (2001), 950-955. (Pubitemid 32121168)
29. W. Chen, E.A. Evans, R.P. McEver and C. Zhu, Monitoring receptor-ligand interactions between surfaces by thermal fluctuations, Biophys. J. 94 (2008), 694-701.
30. Y. Chen, D.K. Yao and J.Y Shao, The constitutive equation for membrane tether extraction, Ann. Biomed. Eng. 38 (2010), 3756-3765.
31. B.C. Chesnutt, D.F. Smith, N.A. Raffler et al., Induction of LFA-1-dependent neutrophil rolling on ICAM-1 by engagement ofE-selectin, Microcirculation 13 (2006), 99-109. (Pubitemid 43216123)
32. E.Y Chiang, A. Hidalgo, J. Chang and P.S. Frenette, Imaging receptor microdomains on leukocyte subsets in live mice, Nat. Methods 4 (2007), 219-222. (Pubitemid 46358870)
33. E.R. Damiano, J. Westheider, A. Tozeren and K. Ley, Variation in the velocity, deformation, and adhesion energy density ofleukocytes rolling within venules, Circ. Res. 79 (1996), 1122-1130. (Pubitemid 26404144)
34. M. Dembo, On peeling an adherent cell from a surface, in: Some Mathematical Problems in Biology, B. Goldstein and C. Wofsy, eds, Vol. 24, American Mathematical Society, Providence, RI, 1994, pp. 51-77.
35. M. Dembo, D.C. Torney, K. Saxman and D. Hammer, The reaction limited kinetics of membrane-to-surface adhesion and detachment, Proc. Roy. Soc. London B 234 (1988), 55-83.
36. C. Dong, J. Cao, EJ. Struble and H.H. Lipowsky, Mechanics of leukocyte deformation and adhesion to endothelium in shear flow, Ann. Biomed. Eng. 27 (1999), 298-312. (Pubitemid 129647572)
37. C. Dong and X.X. Lei, Biomechanics of cell rolling: shear flow, cell-surface adhesion, and cell deformability, J. Biomech. 33 (2000), 35-43.
38. H. Dutrochet, Recherches anatomiques etphysiologiques sur la structure intime des animaux et des vegetaux, et sur leur motilite, Baillière et Fils, Paris, 1824.
39. K.E. Edmondson, WS. Denney and S.L. Diamond, Neutrophil-bead collision assay: pharmacologically induced changes in membrane mechanics regulate the PSGL-1/P-selectin adhesion lifetime, Biophys. J. 89 (2005), 3603-3614. (Pubitemid 41636112)
40. T.K. Epperson, K.D. Patel, R.P McEver and R.D. Cummings, Noncovalent association of P-selectin glycoprotein ligand-1 and minimal determinants for binding to P-selectin, J. Biol. Chem. 275 (2000), 7839-7853. (Pubitemid 30159691)
41. MJ. Eppihimer, B. Wolitzky, D.C. Anderson et al., Heterogeneity of expression ofE-and P-selectins in vivo, Circ. Res. 79 (1996), 560-569. (Pubitemid 26276916)
42. E.E. Eriksson, No detectable endothelial-or leukocyte-derived L-selectin ligand activity on the endothelium in inflamed cremaster muscle venules, J. Leukoc. Biol. 84 (2008), 93-103. (Pubitemid 351960284)
43. E.E. Eriksson, X. Xie, J. Werr et al., Importance of primary capture and L-selectin-dependent secondary capture in leukocyte accumulation in inflammation and atherosclerosis in vivo, J. Exp. Med. 194 (2001), 205-217. (Pubitemid 32673353)
44. S.L. Erlandsen, S.R. Hasslen and R.D. Nelson, Detection and spatial distribution of the beta 2 integrin (Mac-1) and L-selectin (LECAM-1) adherence receptors on human neutrophils by high-resolution field emission SEM, J. Histochem. Cytochem. 41 (1993), 327-333. (Pubitemid 23061918)
45. E. Evans, V. Heinrich, A. Leung and K. Kinoshita, Nano-to microscale dynamics of P-selectin detachment from leukocyte interfaces. I. Membrane separation from the cytoskeleton, Biophys. J. 88 (2005), 2288-2298. (Pubitemid 40976235)
46. E. Evans, A. Leung, V. Heinrich and C. Zhu, Mechanical switching and coupling between two dissociation pathways in a P-selectin adhesion bond, Proc. Natl. Acad. Sci. USA 101 (2004), 11281-11286. (Pubitemid 39038338)
47. EA. Evans and DA. Calderwood, Forces and bond dynamics in cell adhesion, Science 316 (2007), 1148-1153. (Pubitemid 46877469)
48. E. Finger, R. Bruehl, D. Bainton and T. Springer, A differential role for cell shape in neutrophil tethering and rolling on endothelial selectins under flow, J. Immunol. 157 (1996), 5085-5096. (Pubitemid 126449590)
49. J.C. Firrell and H.H. Lipowsky, Leukocyte margination and deformation in mesenteric venules of rat, Am. J. Physiol. Heart Circ. Physiol. 256 (1989), H1667-H1674.
50. PS. Frenette, T.N. Mayadas, H. Rayburn, R.O. Hynes and D.D. Wagner, Susceptibility to infection and altered hematopoiesis in mice deficient in both P-and E-selectins, Cell 84 (1996), 563-574. (Pubitemid 26071737)
51. J. Fritz, A.G. Katopodis, F Kolbinger and D. Anselmetti, Force-mediated kinetics of single P-selectin/ligand complexes observed by atomic force microscopy, Proc. Natl. Acad. Sci. USA 95 (1998), 12783-12288.
52. J.G. Geng, M.P Bevilacqua, K.L. Moore, T.M. McIntyre, S.M. Prescott, J.M. Kim, G.A. Bliss, G.A. Zimmerman and R.P McEver, Rapid neutrophil adhesion to activated endothelium mediated by GMP-140, Nature 343 (1990), 757-760.
53. DJ. Goetz, M.E. El-Sabban, B.U. Pauli and DA. Hammer, Dynamics ofneutrophil rolling over stimulated endothelium in vitro, Biophys. J. 66 (1994), 2202-2209. (Pubitemid 24167973)
54. AJ. Goldman, R.G. Cox and H. Brenner, Slow viscous motion of a sphere parallel to a plane wall. II. Couette flow, Chem. Eng. Sci. 22 (1967), 653-660.
55. H.L. Goldsmith and S. Spain, Margination of leukocytes in blood flow through small tubes, Microvasc. Res. 27 (1984), 204-222. (Pubitemid 14152691)
56. M. Gopalakrishnan, K. Forsten-Williams, M.A. Nugent and U.C. Tauber, Effects of receptor clustering on ligand dissociation kinetics: theory and simulations, Biophys. J. 89 (2005), 3686-3700. (Pubitemid 41725594)
57. U. Gotsch, U. Jager, M. Dominis and D. Vestweber, Expression of P-selectin on endothelial cells is upregulated by LPS and TNF-alpha in vivo, Cell Adhes. Commun. 2 (1994), 7-14. (Pubitemid 24157841)
58. J.D. Griffin, O. Spertini, TJ. Ernst et al., Granulocyte-macrophage colony-stimulating factor and other cytokines regulate surface expression of the leukocyte adhesion molecule-1 on human neutrophils, monocytes, and their precursors, J. Immunol. 145 (1990), 576-584. (Pubitemid 20252365)
59. M. Hahne, U. Jager, S. Isenmann, R. Hallmann and D. Vestweber, Five tumor necrosis factor-inducible cell adhesion mechanisms on the surface of mouse endothelioma cells mediate the binding of leukocytes, J. Cell Biol. 121 (1993), 655-664. (Pubitemid 23131276)
60. D.A. Hammer and S.M. Apte, Simulation of cell rolling and adhesion on surfaces in shear flow: general results and analysis of selectin-mediated neutrophil adhesion, Biophys. J. 63 (1992), 35-57.
61. W. Hanley, O. McCarty, S. Jadhav et al., Single molecule characterization of P-selectin/ligand binding, J. Biol. Chem. 278 (2003), 10556-10561. (Pubitemid 36800324)
62. W.D. Hanley, D. Wirtz and K. Konstantopoulos, Distinct kinetic and mechanical properties govern selectin-leukocyte interactions, J. Cell Sci. 117 (2004), 2503-2511. (Pubitemid 38877846)
63. J. Happel and H. Brenner, Low Reynolds Number Hydrodynamics, Prentice-Hall, Englewood Cliffs, NJ, 1965.
64. R. Hattori, K. Hamilton, R. Fugate et al., Stimulated secretion of endothelial von Willebrand factor is accompanied by rapid redistribution to the cell surface of the intracellular granule membrane protein GMP-140, J. Biol. Chem. 264 (1989), 7768-7771. (Pubitemid 19137247)
65. V. Heinrich, A. Leung and E. Evans, Nano-to microscale dynamics of P-selectin detachment from leukocyte interfaces. II. Tether flow terminated by P-selectin dissociation from PSGL-1, Biophys. J. 88 (2005), 2299-2308. (Pubitemid 40976236)
66. S. Hemmerich, A. Bistrup, M.S. Singer et al., Sulfation of L-selectin ligands by an HEV-restricted sulfotransferase regulates lymphocyte homing to lymph nodes, Immunity 15 (2001), 237-247. (Pubitemid 32816873)
67. A. Hidalgo, A.J. Peired, M.K. Wild et al., Complete identification of E-selectin ligands on neutrophils reveals distinct functions of PSGL-1, ESL-1, and CD44, Immunity 26 (2007), 477-489. (Pubitemid 46603003)
68. C.A.S. Hill, S.R. Alexander and B. Walcheck, Indirect capture augments leukocyte accumulation on P-selectin in flowing whole blood, J. Leukoc. Biol. 73 (2003), 464-471. (Pubitemid 38040092)
69. R.M. Hochmuth, Micropipette aspiration ofliving cells, J. Biomech. 33 (2000), 15-22.
70. R.M. Hochmuth, J.Y. Shao, J. Dai and M.P Sheetz, Deformation and flow of membrane into tethers extracted from neuronal growth cones, Biophys. J. 70 (1996), 358-369. (Pubitemid 26021474)
71. J. Huang, J. Chen, S.E. Chesla et al., Quantifying the effects of molecular orientation and length on two-dimensional receptor-ligand binding kinetics, J. Biol. Chem. 279 (2004), 44915-44923. (Pubitemid 39430904)
72. W.C. Hwang and R.E. Waugh, Energy of dissociation of lipid bilayer from the membrane skeleton of red blood cells, Biophys. J. 72 (1997), 2669-2678. (Pubitemid 27227602)
73. S. Jadhav, CD. Eggleton and K. Konstantopoulos, A 3-D computational model predicts that cell deformation affects selectin-mediated leukocyte rolling, Biophys. J. 88 (2005), 96-104. (Pubitemid 40070661)
74. M. Jin, I. Andricioaei and T.A. Springer, Conversion between three conformational states of integrin I domains with a C-terminal pull spring studied with molecular dynamics, Structure 12 (2004), 2137-2147. (Pubitemid 39593193)
75. U. Jung, D.C. Bullard, T.F. Tedder and K. Ley, Velocity differences between L-and P-selectin-dependent neutrophil rolling in venules of mouse cremaster muscle in vivo, Am. J. Physiol. Heart Circ. Physiol. 271 (1996), H2740-H2747.
76. U. Jung and K. Ley, Regulation of E-selectin, P-selectin, and intercellular adhesion molecule 1 expression in mouse cremaster muscle vasculature, Microcirculation 4 (1997), 311-319. (Pubitemid 127674014)
77. U. Jung and K. Ley, Mice lacking two or all three selectins demonstrate overlapping and distinct functions for each selectin, J. Immunol. 162 (1999), 6755-6762. (Pubitemid 29309402)
78. U. Jung, K.E. Norman, K. Scharffetter-Kochanek, A.L. Beaudet and K. Ley, Transit time of leukocytes rolling through venules controls cytokine-induced inflammatory cell recruitment in vivo, J. Clin. Invest. 102 (1998), 1526-1533. (Pubitemid 28492219)
79. M.A. Jutila, L. Rott, E.L. Berg and E.C. Butcher, Function and regulation of the neutrophil MEL-14 antigen in vivo: comparison with LFA-1 and MAC-1, J. Immunol. 143 (1989), 3318-3324. (Pubitemid 20010162)
80. K.E. Kadash, M.B. Lawrence and S.L. Diamond, Neutrophil string formation: Hydrodynamic thresholding and cellular deformation during cell collisions, Biophys. J. 86 (2004), 4030-4039. (Pubitemid 38780278)
81. G.S. Kansas, Selectins and their ligands: current concepts and controversies, Blood 88 (1996), 3259-3287. (Pubitemid 26365560)
82. R. Karnik, S. Hong, H. Zhang et al., Nanomechanical control of cell rolling in two dimensions through surface patterning of receptors, Nano Lett. 8 (2008), 1153-1158.
83. Y. Katayama, A. Hidalgo, J. Chang et al., CD44 is a physiological E-selectin ligand on neutrophils, J. Exp. Med. 201 (2005), 1183-1189. (Pubitemid 40637228)
84. H. Kawashima, B. Petryniak, N. Hiraoka et al., N-acetylglucosamine-6-O- sulfotransferases 1 and 2 cooperatively control lymphocyte homing through L-selectin ligand biosynthesis in high endothelial venules, Nat. Immunol. 6 (2005), 1096-1104. (Pubitemid 41541787)
85. D.B. Khismatullin, The cytoskeleton and deformability of white blood cells, in: Leukocyte Adhesion, K. Ley, ed., Vol. 64, Academic Press, San Diego, 2009, pp. 47-111.
86. D.B. Khismatullin and G.A. Truskey, A 3D numerical study of the effect of channel height on leukocyte deformation and adhesion in parallel-plate flow chambers, Microvasc. Res. 68 (2004), 188-202. (Pubitemid 40288115)
87. D.B. Khismatullin and G.A. Truskey, Three-dimensional numerical simulation of receptor-mediated leukocyte adhesion to surfaces: Effects ofcell deformability and viscoelasticity, Phys. Fluids 17 (2005), 031505.
88. MB. Kim and I.H. Sarelius, Role of shear forces and adhesion molecule distribution on P-selectin-mediated leukocyte rolling in postcapillary venules, Am. J. Physiol. Heart Circ. Physiol. 287 (2004), H2705-H2711. (Pubitemid 39557143)
89. MR. King, V. Heinrich, E. Evans and D.A. Hammer, Nano-to-micro scale dynamics of P-selectin detachment from leukocyte interfaces. III. Numerical simulation of tethering under flow, Biophys. J. 88 (2005), 1676-1683. (Pubitemid 40976184)
90. T.K. Kishimoto, M.A. Jutila, E.L. Berg and E.C. Butcher, Neutrophil Mac-1 and MEL-14 adhesion proteins inversely regulated by chemotactic factors, Science 245 (1989), 1238-1241. (Pubitemid 19238748)
91. A.G. Klopocki, T. Yago, P. Mehta et al., Replacing a lectin domain residue in L-selectin enhances binding to P-selectin glycoprotein ligand-1 but not to 6-sulfo-sialyl Lewis x, J. Biol. Chem. 283 (2008), 11493-11500.
92. K. Konstantopoulos, W.D. Hanley and D. Wirtz, Receptor-ligand binding: 'catch' bonds finally caught, Curr. Biol. 13 (2003), R611-R613. (Pubitemid 36953296)
93. K. Konstantopoulos, S. Kukreti and L.V. McIntire, Biomechanics of cell interactions in shear fields, Adv. Drug Deliv. Rev. 33 (1998), 141-164. (Pubitemid 28403540)
94. E.F. Krasik and D.A. Hammer, A semianalytic model of leukocyte rolling, Biophys. J. 87 (2004), 2919-2930. (Pubitemid 40468553)
95. EJ. Kunkel, J.E. Chomas and K. Ley, Role ofprimary and secondary capture for leukocyte accumulation in vivo, Circ. Res. 82 (1998), 30-38. (Pubitemid 28074016)
96. EJ. Kunkel, J.L. Dunne and K. Ley, Leukocyte arrest during cytokine-dependent inflammation in vivo, J. Immunol. 164 (2000), 3301-3308. (Pubitemid 30148994)
97. EJ. Kunkel, U. Jung, D.C. Bullard et al., Absence of trauma-induced leukocyte rolling in mice deficient in both P-selectin and intercellular adhesion molecule 1, J. Exp. Med. 183 (1996), 57-65.
98. EJ. Kunkel and K. Ley, Distinct phenotype of E-selectin-deficient mice: E-selectin is required for slow leukocyte rolling in vivo, Circ. Res. 79 (1996), 1196-1204. (Pubitemid 26404152)
99. Y. Kuwano, O. Spelten, H. Zhang et al., Rolling on E-or P-selectin induces the extended but not high-affinity conforma-tion ofLFA-1 in neutrophils, Blood 116 (2010), 617-624.
100. M.A. Labow, C.R. Norton, J.M. Rumberger et al., Characterization of E-selectin-deficient mice: demonstration of overlapping function of the endothelial selectins, Immunity 1 (1994), 709-720. (Pubitemid 124000734)
101. H.F. Langer and T. Chavakis, Leukocyte-endothelial interactions in inflammation, J. Cell. Mol. Med. 13 (2009), 1211-1220.
102. M.B. Lawrence, D.F Bainton and T.A. Springer, Neutrophil tethering to and rolling on E-selectin are separable by requirement for L-selectin, Immunity 1 (1994), 137-145.
103. M.B. Lawrence, G.S. Kansas, EJ. Kunkel and K. Ley, Threshold levels of fluid shear promote leukocyte adhesion through selectins (CD62L,P,E), J. Cell Biol. 136 (1997), 717-727. (Pubitemid 27083771)
104. M.B. Lawrence, CW. Smith, S.G. Eskin and L.V. McIntire, Effect of venous shear stress on CD18-mediated neutrophil adhesion to cultured endothelium, Blood 75 (1990), 227-237. (Pubitemid 20031513)
105. M.B. Lawrence and T.A. Springer, Leukocytes roll on a selectin at physiological flow rates: distinction from and prerequisite for adhesion through integrins, Cell 65 (1991), 859-874.
106. M.B. Lawrence and T.A. Springer, Neutrophils roll on E-selectin, J. Immunol. 151 (1993), 6338-6346. (Pubitemid 23340380)
107. M. Lenter, A. Levinovitz, S. Isenmann and D. Vestweber, Monospecific and common glycoprotein ligands for E-and P-selectin on myeloid cells, J. Cell Biol. 125 (1994), 471-481. (Pubitemid 24135959)
108. A. Lepännen, P. Mehta, Y-B. Ouyang, T. Ju, J. Helin, K.L. Moore, I. van Die, W.M. Canfield, R.P McEver and R.D. Cummings, A novel glycosulfopeptide binds to P-selectin and inhibits leukocyte adhesion to P-selectin, J. Biol. Chem. 274 (1999), 24838-24848.
109. A. Leppänen, S.P White, J. Helin, R.P McEver and R.D. Cummings, Binding ofglycosulfopeptides to P-selectin requires stereospecific contributions of individual tyrosine sulfate and sugar residues, J. Biol. Chem. 275 (2000), 39569-39578. (Pubitemid 32058983)
110. A. Leppanen, T. Yago, V.I. Otto et al., Model glycosulfopeptides from P-selectin glycoprotein ligand-1 require tyrosine sulfation and a core 2-branched O-glycan to bind to L-selectin, J. Biol. Chem. 278 (2003), 26391-26400. (Pubitemid 36876778)
111. J.D. Levin, H.P Ting-Beall and R.M. Hochmuth, Correlating the kinetics ofcytokine-induced E-selectin adhesion and expression on endothelial cells, Biophys. J. 80 (2001), 656-667. (Pubitemid 32128320)
112. K. Ley, D.C. Bullard, M.L. Arbones, R. Bosse, D. Vestweber, T.F Tedder and A.L. Beaudet, Sequential contribution of L-and P-selectin to leukocyte rolling in vivo, J. Exp. Med. 181 (1995), 669-675.
113. K. Ley, C. Laudanna, M.I. Cybulsky and S. Nourshargh, Getting to the site of inflammation: the leukocyte adhesion cascade updated, Nat. Rev. Immunol. 7 (2007), 678-689. (Pubitemid 47327397)
114. K. Ley, T.F Tedder and G.S. Kansas, L-selectin can mediate leukocyte rolling in untreated mesenteric venules in vivo independent ofE-or P-selectin, Blood 82 (1993), 1632-1638. (Pubitemid 23263983)
115. K. Ley, A. Zakrzewicz, C. Hanski, L.M. Stoolman and G.S. Kansas, Sialylated O-glycans and L-selectin sequentially mediate myeloid cell rolling in vivo, Blood 85 (1995), 3727-3735.
116. F. Li, H.P. Erickson, J.A. James, K.L. Moore, R.D. Cummings and R.P. McEver, Visualization ofP-selectin glycoprotein ligand-1 as a highly extended molecule and mapping ofprotein epitopes for monoclonal antibodies, J. Biol. Chem. 271 (1996), 6342-6348. (Pubitemid 26095442)
117. F. Li, PP. Wilkins, S. Crawley, J. Weinstein, R.D. Cummings and R.P McEver, Post-translational modifications of recombinant P-selectin glycoprotein ligand-1 required for binding to P-and E-selectin, J. Biol. Chem. 271 (1996), 3255-3264. (Pubitemid 26055629)
118. Y.-C. Lim, K. Snapp, G.S. Kansas, R. Camphausen, H. Ding and F.W. Luscinskas, Important contributions ofP-selectin glycoprotein ligand-1-mediated secondary capture to human monocyte adhesion to P-selectin, E-selectin, and TNF-α-activated endothelium under flow in vitro, J. Immunol. 161 (1998), 2501-2508. (Pubitemid 28397067)
119. L. Lindbom, X. Xie, J. Raud and P. Hedqvist, Chemoattractant-induced firm adhesion of leukocytes to vascular endothelium in vivo is critically dependent on initial leukocyte rolling, Acta Physiol. Scand. 146 (1992), 415-421. (Pubitemid 23008339)
120. M.D. Linden and D.E. Jackson, Platelets: pleiotropic roles in atherogenesis and atherothrombosis, Int. J. Biochem. Cell Biol. 42 (2010), 1762-1766.
121. W.-J. Liu, V. Ramachandran, J. Kang et al., Identification of N-terminal residues on P-selectin glycoprotein ligand-1 required for binding to P-selectin, J. Biol. Chem. 273 (1998), 7078-7087. (Pubitemid 28160377)
122. J. Lou, T. Yago, A.G. Klopocki, P. Mehta et al., Flow-enhanced adhesion regulated by a selectin interdomain hinge, J. Biol. Chem. 174 (2006), 1107-1117. (Pubitemid 44455197)
123. J. Lou and C. Zhu, A structure-based sliding-rebinding mechanism for catch bonds, Biophys. J. 92 (2007), 1471-1485. (Pubitemid 46393460)
124. B.T. Marshall, M. Long, J.W. Piper et al., Direct observation of catch bonds involving cell-adhesion molecules, Nature 423 (2003), 190-193. (Pubitemid 36569544)
125. M. Martinez, M. Joffraud, S. Giraud et al., Regulation of PSGL-1 interactions with L-selectin, P-selectin, and E-selectin: role of human fucosyltransferase-IV and-VII, J. Biol. Chem. 280 (2005), 5378-5390. (Pubitemid 40280012)
126. T.N. Mayadas, R.C. Johnson, H. Rayburn, R.O. Hynes and D.D. Wagner, Leukocyte rolling and extravasation are severely compromised in P selectin-deficient mice, Cell 74 (1993), 541-554. (Pubitemid 23244619)
127. R.P McEver, Selectins: lectins that initiate cell adhesion under flow, Curr. Opin. Cell Biol. 14 (2002), 581-586. (Pubitemid 35247741)
128. R.P McEver, Rolling back neutrophil adhesion, Nat. Immunol. 11 (2010), 282-284.
129. R.P McEver, K.L. Moore and R.D. Cummings, Leukocyte trafficking mediated by selectin-carbohydrate interactions, J. Biol. Chem. 270 (1995), 11025-11028.
130. R.P McEver and C. Zhu, Rolling cell adhesion, Annu. Rev. Cell. Dev. Biol. 26 (2010), 363-396.
131. P. Mehta, R.D. Cummings and R.P McEver, Affinity andkinetic analysis ofP-selectinbinding to P-selectin glycoprotein ligand-1, J. Biol. Chem. 273 (1998), 32506-32513. (Pubitemid 28557626)
132. J. Mitoma, X. Bao, B. Petryanik et al., Critical functions of N-glycans in L-selectin-mediated lymphocyte homing and recruitment, Nat. Immunol. 8 (2007), 409-418. (Pubitemid 46745416)
133. K.L. Moore, S.F. Eaton, D.E. Lyons et al., The P-selectin glycoprotein ligand form human neutrophils displays sialylated, fucosylated, O-linked poly-N-acetyllactosamine, J. Biol. Chem. 269 (1994), 23318-23327. (Pubitemid 24283324)
134. K.L. Moore, K.D. Patel, R.E. Bruehl et al., P-selectin glycoprotein ligand-1 mediates rolling of human neutrophils on P-selectin, J. Biol. Chem. 128 (1995), 661-671.
135. W.A. Muller, Leukocyte-endothelial cell interactions in the inflammatory response, Lab. Invest. 82 (2002), 521-533. (Pubitemid 34522364)
136. M.W. Nicholson, A.N. Barclay, M.S. Singer et al., Affinity and kinetic analysis of L-selectin (CD62L) binding to glycosylation-dependent cell-adhesionmolecule-1, J. Biol. Chem. 273 (1998), 763-770. (Pubitemid 28049164)
137. L. Nimrichter, M.M. Burdick, K. Aoki et al., E-selectin receptors on human leukocytes, Blood 112 (2008), 3744-3752.
138. U. Nobis, A.R. Pries, G.R. Cokelet and P. Gaehtgens, Radial distribution of white cells during blood flow in small tubes, Microvasc. Res. 29 (1985), 295-304. (Pubitemid 16158225)
139. K.E. Norman, A.G. Katopodis, G. Thoma et al., P-selectin glycoprotein ligand-1 supports rolling on E-and P-selectin in vivo, Blood 96 (2000), 3585-3591.
140. K.E. Norman, K.L. Moore, R.P McEver and K. Ley, Leukocyte rolling in vivo is mediated by P-selectin glycoprotein ligand-1, Blood 86 (1995), 4417-4421.
141. H. Oh and S.L. Diamond, Ethanol enhances neutrophil membrane tether growth and slows rolling on P-selectin but reduces capture from flow and firm arrest on IL-1-treated endothelium, J. Immunol. 181 (2008), 2472-2482.
142. H. Oh, E.R. Mohler III, A. Tian et al., Membrane cholesterol is a biomechanical regulator of neutrophil adhesion, Arterioscler. Thromb. Vasc. Biol. 29 (2009), 1290-1297.
143. E.Y.H. Park, MJ. Smith, E.S. Stropp et al., Comparison of PSGL-1 microbead and neutrophil rolling: microvillus elongation stabilizes P-selectin bond clusters, Biophys. J. 82 (2002), 1835-1847. (Pubitemid 34280800)
144. CD. Paschall and M.B. Lawrence, L-selectin shear thresholding modulates leukocyte secondary capture, Ann. Biomed. Eng. 36 (2008), 622-631.
145. K.D. Patel, M.U. Nollert and R.P. McEver, P-selectin must extend a sufficient length from the plasma membrane to mediaterolling ofneutrophils, J. Cell Biol. 131 (1995), 1893-1902. (Pubitemid 26007984)
146. P. Pawar, S. Jadhav, CD. Eggleton and K. Konstantopoulos, Roles of cell and microvillus deformation and receptorligand binding kinetics in cell rolling, Am. J. Physiol. Heart Circ. Physiol. 295 (2008), H1439-H1450.
147. CS. Peskin and D.M. McQueen, A 3-dimensional computational method for blood-flow in the heart. 1. Immersed elastic fibers in a viscous incompressible fluid, J. Comput. Phys. 81 (1989), 372-405.
148. B. Petri, M. Phillipson and P. Kubes, The physiology of leukocyte recruitment: an in vivo perspective, J. Immunol. 180 (2008), 6439-6446.
149. U.T. Phan, T.T. Waldron and T.A. Springer, Remodeling of the lectin-EGF-like domain interface in P-and L-selectin increases adhesiveness and shear resistance under hydrodynamic force, Nat. Immunol. 7 (2006), 883-889. (Pubitemid 44084096)
150. M. Phillipson, B. Heit, P. Colarusso et al., Intraluminal crawling of neutrophils to emigration sites: a molecularly distinct process from adhesion in the recruitment cascade, J. Exp. Med. 203 (2006), 2569-2575. (Pubitemid 44833334)
151. M.K. Pospieszalska and K. Ley, Dynamics of microvillus extension and tether formation in rolling leukocytes, Cell. Mol. Bioeng. 2 (2009), 207-217.
152. M.K. Pospieszalska and K. Ley, Modeling leukocyte rolling, in: Leukocyte Adhesion, K. Ley, ed., Vol. 64, Elsevier, San Diego, CA, 2009, pp. 221-273, Chapter 8.
153. M.K. Pospieszalska, A. Zarbock, J.E. Pickard and K. Ley, Event-tracking model of adhesion identifies load-bearing bonds in rolling leukocytes, Microcirculation 16 (2009), 115-130.
154. T. Pouyani and B. Seed, PSGL-1 recognition of P-selectin is controlled by a tyrosine sulfation consensus at the PSGL-1 amino terminus, Cell 83 (1995), 333-343.
155. J.L. Python, K.O. Wilson, J.H. Snook et al., The viscoelastic properties of microvilli are dependent upon the cell-surface molecule, Biochem. Biophys. Res. Commun. 397 (2010), 621-625.
156. V. Ramachandran, M. Williams, T. Yago et al., Dynamic alterations of membrane tethers stabilize leukocyte rolling on P-selectin, Proc. Natl. Acad. Sci. USA 101 (2004), 13519-13524. (Pubitemid 39238435)
157. V. Ramachandran, T. Yago, T.K. Epperson et al., Dimerization of a selectin and its ligand stabilizes cell rolling and enhances tether strength in shear flow, Proc. Natl. Acad. Sci. USA 98 (2001), 10166-10171. (Pubitemid 32802992)
158. S.D. Rosen, Ligands for L-selectin: homing, inflammation, and beyond, Annu. Rev. Immunol. 22 (2004), 129-156. (Pubitemid 38680420)
159. B. Sabass, M.L. Gardel, CM. Waterman and U.S. Schwarz, High resolution traction force microscopy based on experimental and computational advances, Biophys. J. 94 (2008), 207-220.
160. D. Sako, XJ. Chang, K.M. Barone et al., Expression cloning of a functional glycoprotein ligand for P-selectin, Cell 75 (1993), 1179-1186. (Pubitemid 24006114)
161. W.E. Sanders, R.W. Wilson, CM. Ballantyne and A.L. Beaudet, Molecular cloning and analysis of in vivo expression of murine P-selectin, Blood 80 (1992), 795-800.
162. K.K. Sarangapani, T. Yago, A.G. Klopocki et al., Low force decelerates L-selectin dissociation from P-selectin glycoprotein ligand-1 and endoglycan, J. Biol. Chem. 279 (2004), 2291-2298. (Pubitemid 38084502)
163. U.Y Schaff, M.M. Xing, K.K. Lin et al., Vascular mimetics based on microfluidics for imaging the leukocyte-endothelial inflammatory response, Lab Chip 7 (2007), 448-456. (Pubitemid 46496555)
164. G. Schmid-Schönbein, Y. Shih and S. Chien, Morphometry ofhuman leukocytes, Blood 56 (1980), 866-875.
165. G.W. Schmid-Schönbein, S. Usami, R. Skalak and S. Chien, The interaction of leukocytes and erythrocytes in capillary and postcapillary vessels, Microvasc. Res. 19 (1980), 45-70. (Pubitemid 10207818)
166. BJ. Schmidt, J.A. Papin and M.B. Lawrence, Nano-motion dynamics are determined by surface-tethered selectin mechanokinetics and bond formation, PLoS Comput. Biol. 5 (2009), e1000612.
167. D.W. Schmidtke and S.L. Diamond, Direct observation of membrane tethers formed during neutrophil attachment to platelets or P-selectin under physiological flow, J. Cell Biol. 149 (2000), 719-729. (Pubitemid 30252404)
168. J. Schmitz, M. Benoit and K.E. Gottschalk, The viscoelasticity of membrane tethers and its importance for cell adhesion, Biophys. J. 95 (2008), 1448-1459.
169. H. Setiadi and R.P McEver, Signal-dependent distribution of cell surface P-selectin in clathrin-coated pits affects leukocyte rolling under flow, J. Cell Biol. 163 (2003), 1385-1395. (Pubitemid 38032098)
170. H. Setiadi and R.P McEver, Clustering endothelial E-selectin in clathrin-coated pits and lipid rafts enhances leukocyte adhesion under flow, Blood 111 (2008), 1989-1998. (Pubitemid 351451509)
171. H. Setiadi, G. Sedgewick, S.L. Erlandsen and R.P McEver, Interaction of the cytoplasmic domain of P-selectin with clathrin-coated pits enhance leukocyte adhesion under flow, J. Cell Biol. 142 (1998), 859-871. (Pubitemid 28381501)
172. J.-Y. Shao, Biomechanics ofleukocyte and endothelial cell surface, in: Leukocyte Adhesion, K. Ley, ed., Vol. 64, Elsevier, San Diego, CA, 2009, pp. 25-45, Chapter 2.
173. J.-Y. Shao, H.P Ting-Beall and R.M. Hochmuth, Static and dynamic lengths of neutrophil microvilli, Proc. Natl. Acad. Sci. USA 95 (1998), 6797-6802. (Pubitemid 28278060)
174. J.Y Shao and G. Xu, The adhesion between a microvillus-bearing cell and a ligand-coated substrate: a Monte Carlo study, Ann. Biomed. Eng. 35 (2007), 397-407. (Pubitemid 46325727)
175. A. Shigeta, M. Matsumoto, T.F. Tedder et al., An L-selectin ligand distinct from P-selectin glycoprotein ligand-1 is expressed on endothelial cells and promotes neutrophil rolling in inflammation, Blood 112 (2008), 4915-4923.
176. M. Shimaoka, T. Xiao, J.H. Liu et al., Structures of the alpha L I domain and its complex with ICAM-1 reveal a shapeshifting pathway for integrin regulation, Cell 112 (2003), 99-111. (Pubitemid 36106422)
177. S.I. Simon and C.E. Green, Molecular mechanics and dynamics of leukocyte recruitment during inflammation, Annu. Rev. Biomed. Eng. 7 (2005), 151-185. (Pubitemid 41170187)
178. CW. Smith, T.K. Kishimoto, O. Abbassi et al., Chemotactic factors regulate lectin adhesion molecule 1 (LECAM-1)-dependent neutrophil adhesion to cytokine-stimulated endothelial cells in vitro, J. Clin. Invest. 87 (1991), 609-618.
179. L.A. Smith, H. Aranda-Espinoza, J.B. Haun et al., Neutrophil traction stresses are concentrated in the uropod during migration, Biophys. J. 92 (2007), L58-L60. (Pubitemid 46536410)
180. MJ. Smith, E.L. Berg and M.B. Lawrence, A direct comparison of selectin-mediated transient, adhesive events using high temporal resolution, Biophys. J. 77 (1999), 3371-3383.
181. M.L. Smith, M. Sperandio, E.V. Galkina and K. Ley, Autoperfused mouse flow chamber reveals synergistic neutrophil accumulation through P-selectin and E-selectin, J. Leukoc. Biol. 76 (2004), 985-993. (Pubitemid 39458710)
182. x and PSGL-1, Cell 103 (2000), 467-479.
183. M. Sperandio, M.L. Smith, S.B. Forlow et al., P-selectin glycoprotein ligand-1 mediates L-selectin-dependent leukocyte rolling in venules, J. Exp. Med. 197 (2003), 1355-1363. (Pubitemid 36617782)
184. M. Sperandio, A. Thatte, D. Foy et al., Severe impairment of leukocyte rolling in venules of core 2 glucosaminyltransferase-deficient mice, Blood 97 (2001), 3812-3819.
185. O. Spertini, A.S. Cordey, N. Monai et al., P-selectin glycoprotein ligand 1 is a ligand for L-selectin on neutrophils, monocytes, and CD34+ hematopoietic progenitor cells, J. Cell Biol. 135 (1996), 523-531. (Pubitemid 26359344)
186. T.A. Springer, Adhesion receptors of the immune system, Nature 346 (1990), 425-434.
187. T.A. Springer, Traffic signals for lymphocyte recirculation and leukocyte emigration: the multistep paradigm, Cell 76 (1994), 301-314. (Pubitemid 24046692)
188. T.A. Springer, Structural basis for selectin mechanochemistry, Proc. Natl. Acad. Sci. USA 106 (2009), 91-96.
189. M. Steegmaier, E. Borges, J. Berger et al., The E-selectin-ligand ESL-1 is located in the Golgi as well as on microvilli on the cell surface, J. Cell Sci. 110 (1997), 687-694. (Pubitemid 27156318)
190. M. Subramaniam, S. Saffaripour, S.R. Watson et al., Reduced recruitment of inflammatory cells in a contact hypersensitivity response in P-selectin-deficient mice, J. Exp. Med. 181 (1995), 2277-2282.
191. P. Sundd, E. Gutierrez, M.K. Pospieszalska et al., Quantitative dynamic footprinting microscopy reveals mechanisms of neutrophil rolling, Nat. Methods 7 (2010), 821-824.
192. C. Tauxe, X. Xie, M. Joffraud et al., P-selectin glycoprotein ligand-1 decameric repeats regulate selectin-dependent rolling under flow conditions, J. Biol. Chem. 283 (2008), 28536-28545.
193. T.F. Tedder, D.A. Steeber, A. Chen and P. Engel, The selectins: vascular adhesion molecules, FASEB J. 9 (1995), 866-873.
194. T.F. Tedder, D.A. Steeber and P. Pizcueta, L-selectin-deficient mice have impaired leukocyte recruitment into inflammatory sites, J. Exp. Med. 181 (1995), 2259-2264.
195. D.FJ. Tees, R.E. Waugh and D.A. Hammer, A microcantilever device to assess the effect of force on the lifetime of selectin-carbohydrate bonds, Biophys. J. 80 (2001), 668-682. (Pubitemid 32128321)
196. A. Tözeren and K. Ley, How do selectins mediate leukocyte rolling in venules?, Biophys. J. 63 (1992), 700-709.
197. L. Tu, P.G. Murphy, X. Li and T.F Tedder, L-selectin ligands expressed by human leukocytes are HECA-452 antibodydefined carbohydrate epitopes preferentially displayed by P-selectin glycoprotein ligand-1, J. Immunol. 163 (1999), 5070-5078. (Pubitemid 29501276)
198. K. Uchimura, J.M. Gauguet, M.S. Singer et al., A major class of L-selectin ligands is eliminated in mice deficient in two sulfotransferases expressed in high endothelial venules, Nat. Immunol. 6 (2005), 1105-1113. (Pubitemid 41541788)
199. S. Ushiyama, T. Laue, K. Moore et al., Structural and functional characterization of monomeric soluble P-selectin and comparison with membrane P-selectin, J. Biol. Chem. 268 (1993), 15229-15237. (Pubitemid 23206679)
200. D. Vestweber and J.E. Blanks, Mechanisms that regulate the function of the selectins and their ligands, Physiol. Rev. 79 (1999), 181-213. (Pubitemid 29056952)
201. U.H. von Andrian, J.D. Chambers, L.M. McEvoy et al., Two-step model of leukocyte-endothelial cell interaction in inflammation: distinct roles for LECAM-1 and the leukocyte beta 2 integrins in vivo, Proc. Natl. Acad. Sci. USA 88 (1991), 7538-7542. (Pubitemid 21915188)
202. U.H. von Andrian, S.R. Hasslen, R.D. Nelson, S.L. Erlandsen and E.C. Butcher, A central role for microvillous receptor presentation in leukocyte adhesion under flow, Cell 82 (1995), 989-999.
203. R. Wagner, Zur vergleichenden Physiologie des Blutes, Untersuchungen über Blutkörperchen, Blutbildung, und Blutbahn, nebst Bemerkungen über Blutbewegung, Ernährung und Absonderung, Leopold Voss, Leipzig, 1833.
204. R. Wagner, Icones Physiologicae. Erläuterungstafeln zur Physiologie und Entwicklungsgeschichte, Leopold Voss, Leipzig, 1839.
205. B. Walcheck, K.L. Moore, R.P. McEver and T.K. Kishimoto, Neutrophil-neutrophil interactions under hydrodynamic shear stress involve L-selectin and PSGL-1, J. Clin. Invest. 98 (1996), 1081-1087.
206. T.T. Waldron and T.A. Springer, Transmission of allostery through the lectin domain in selectin-mediated cell adhesion, Proc. Natl. Acad. Sci. USA 106 (2009), 85-90.
207. A. Waller, Microscopic examination of some principal tissues of the animal frame as observed in the tongue of the living frog, toad, etc., London, Edinburgh andDublin Philos. Mag. 29 (1846), 271-287.
208. R.E. Waugh, Membrane tethers, in: Leukocyte Adhesion, K. Ley, ed., Vol. 64, Academic Press, San Diego, CA, 2009, pp. 3-24, Chapter 1.
209. R.E. Waugh and R.G. Bauserman, Physical measurement of bilayer-skeletal separation forces, Ann. Biomed. Eng. 23 (1995), 308-321.
210. R.E. Waugh and R.M. Hochmuth, Mechanical equilibrium of thick, hollow, liquid membrane cylinders, Biophys. J. 52 (1987), 391-400.
211. A. Weller, S. Isenmann and D. Vestweber, Cloning of the mouse endothelial selectins. Expression of both E-and P-selectin is inducible by tumor necrosis factor alpha, J. Biol. Chem. 267 (1992), 15176-15183.
212. M.K. Wild, M.-C. Huang, U. Schulze-Horsel et al., Affinity, kinetics, and thermodynamics of E-selectin binding to E-selectin ligand-1, J. Biol. Chem. 276 (2001), 31602-31612.
213. L. Xia, V. Ramachandran, J.M. McDaniel et al., N-terminal residues in murine P-selectin glycoprotein ligand-1 required for binding to murine P-selectin, Blood 101 (2003), 552-559. (Pubitemid 36077577)
214. L. Xia, M. Sperandio, T. Yago, J.M. McDaniel et al., P-selectin glycoprotein ligand-1-deficient mice have impaired leukocyte tethering to E-selectin under flow, J. Clin. Invest. 109 (2002), 939-950. (Pubitemid 34275115)
215. G. Xu and J.-Y. Shao, Double tether extraction from human neutrophils and its comparison with CD4+ T-lymphocytes, Biophys. J. 88 (2005), 661-669. (Pubitemid 40070709)
216. G. Xu and J.Y Shao, Human neutrophil surface protrusion under a point load: location independence and viscoelasticity, Am. J. Physiol. Cell Physiol. 295 (2008), C1434-C1444. (Pubitemid 352790353)
217. T. Yago, J. Fu, J.M. McDaniel et al., Core 1-derived O-glycans are essential E-selectin ligands on neutrophils, Proc. Natl. Acad. Sci. USA 107 (2010), 9204-9209.
218. T. Yago, A. Leppanen, H. Qiu, W.D. Marcus, M.U. Nollert, C. Zhu, R.D. Cummings and R.P McEver, Distinct molecular and cellular contributions to stabilizing selectin-mediated rolling under flow, J. Cell Biol. 158 (2002), 787-799. (Pubitemid 34920116)
219. T. Yago, J. Wu, CD. Wey, A.G. Klopocki, C. Zhu and R.P McEver, Catch bonds govern adhesion through L-selectin at threshold shear, J. Cell Biol. 166 (2004), 913-923. (Pubitemid 39249841)
220. T. Yago, V.I. Zarnitsyna, A.G. Klopocki, R.P McEver and C. Zhu, Transport governs flow-enhanced cell tethering through L-selectin at threshold shear, Biophys. J. 92 (2007), 330-342. (Pubitemid 46048441)
221. Y. Yu and J.Y. Shao, Simultaneous tether extraction contributes to neutrophil rolling stabilization: a model study, Biophys. J. 92 (2007), 418-429. (Pubitemid 46145775)
222. A. Zarbock, CL. Abram, M. Hundt, A. Altman, CA. Lowell and K. Ley, PSGL-1 engagement by E-selectin signals through Src kinase Fgr and ITAM adapters DAP12 and FcR gamma to induce slow leukocyte rolling, J. Exp. Med. 205 (2008), 2339-2347.
223. A. Zarbock, CA. Lowell and K. Ley, Spleen tyrosine kinase Syk is necessary for E-selectin-induced alpha(L)beta(2) integrin-mediated rolling on intercellular adhesion molecule-1, Immunity 26 (2007), 773-783. (Pubitemid 46907666)
224. A. Zarbock, H. Muller, Y Kuwano and K. Ley, PSGL-1-dependent myeloid leukocyte activation, J. Leukoc. Biol. 86 (2009), 1119-1124.
225. A. Zarbock, K. Singbartl and K. Ley, Complete reversal of acid-induced acute lung injury by blocking of plateletneutrophil aggregation, J. Clin. Invest. 116 (2006), 3211-3219. (Pubitemid 44878635)
226. Y Zhao, S. Chien and R. Skalak, A stochastic model of leukocyte rolling, Biophys. J. 69 (1995), 1309-1320.
227. C. Zhu, M. Long, S.E. Chesla and P. Bongrand, Measuring receptor/ligand interaction at the single-bond level: experimental and interpretative issues, Ann. Biomed. Eng. 30 (2002), 305-314. (Pubitemid 34690555)
228. C. Zhu, T. Yago, J. Lou et al., Mechanisms for flow-enhanced cell adhesion, Ann. Biomed. Eng. 36 (2008), 604-621.
229. J. Cao, B. Donell, D.R. Deaver, M.B. Lawrence and C. Dong, In vitro side-view imaging technique and analysis of human T-leukemic cell adhesion to ICAM-1 in shear flow, Microvasc Res. 55 (1998), 124-137. (Pubitemid 28368698)
230. M.K. Pospieszalska, I. Lasiecka and K. Ley, Cell protrusions and tethers: a unified approach, Biophys. J. (2011), in press.