Transit time of leukocytes rolling through venules controls cytokine- induced inflammatory cell recruitment in vivo

Journal of Clinical Investigation

Volumn 102, Issue 8, 1998, Pages 1526-1533

  Jung, Unsu ^a   Norman, Keith E ^a,e   Scharffetter Kochanek, Karin ^b   Beaudet, Arthur L ^c   Ley, Klaus ^a,d  

^a UNIVERSITY OF VIRGINIA   (United States)

^b UNIVERSITY OF COLOGNE   (Germany)

^c BAYLOR COLLEGE OF MEDICINE   (United States)

^d UNIVERSITY OF VIRGINIA   (United States)

^e UNIVERSITY OF SHEFFIELD   (United Kingdom)

Author keywords

CD18; Inflammation; Integrin; Intravital microscopy; Rolling; Selectin

Indexed keywords

CD18 ANTIGEN; CYTOKINE; ENDOTHELIAL LEUKOCYTE ADHESION MOLECULE 1; INTEGRIN; INTERLEUKIN 8; TUMOR NECROSIS FACTOR ALPHA;

ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; CONTROLLED STUDY; CREMASTER MUSCLE; LEUKOCYTE ACTIVATION; LEUKOCYTE ADHERENCE; LEUKOCYTE MIGRATION; MALE; MOLECULAR INTERACTION; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN PROTEIN INTERACTION; VENULE;

EID: 0032532669     PISSN: 00219738     EISSN: None     Source Type: Journal    
DOI: 10.1172/JCI119893     Document Type: Article

References (36)

1. Butcher, E.C. 1991. Leukocytc-endothelial cell recognition-three (or more) steps to specificity and diversity. Cell. 67:1033-1036.
2. Springer, T.A. 1995. Traffic signals on endothelium for lymphocyte recirculation and leukocyte emigration. Annu. Rev. Physiol. 57:827-872.
3. 4-integrin, P-selectin, and E-selectin in an allergic model of inflammation. J. Exp. Med. 185:1077-1087.
4. Bullard, D.C., E.J. Kunkel, H. Kubo, M.J. Hicks, I. Lorenzo, N.A. Doyle, C.M. Doerschuk, K. Ley, and A.L. Beaudet. 1996. Infectious susceptibility and severe deficiency of leukocyte rolling and recruitment in E-selectin and P-selectin double mutant mice. J. Exp. Med. 183:1-8.
5. Frenette, P.S., T.N. Mayadas, H. Rayburn, R.O. Hynes, and D.D. Wagner. 1996. Susceptibility to infection and altered hematopoiesis in mice deficient in both P-and E-selectins. Cell. 84:563-574.
6. Arfors, K.-E., C. Lundberg, L. Lindbom, K. Lundberg, P.G. Beatty, and J.M. Harlan. 1987. A monoclonal antibody to the membrane glycoprotein complex CD18 inhibits polymorphonuclear leukocyte accumulation and plasma leakage in vivo. Blood. 69:338-340.
7. Scharffetter-Kochanek, K., H. Lu, D.C. Bullard, K.E. Norman, N. van Nood, S. Grabbe, M. McArthur, I. Lorenzo, K. Mahnke, K. Ley, et al, 1998. Spontaneous skin ulceration and defective T cell function in CD18 null mice. J. Exp. Med. 188:119-131.
8. Jung, U., and K. Ley. 1997. Regulation of E-selectin, P-selectin, and intercellular adhesion molecule 1 expression in mouse cremaster muscle vasculature. Microcirulation. 4:311-319.
9. Ley, K., D.C. Bullard, M.L. Arbonés, R. Bosse, D. Vestweber, T.F. Tedder, and A.L. Beaudet. 1995. Sequential contribution of L-and P-selectin to leukocyte rolling in vivo. J. Exp. Med. 181:669-675.
10. Kunkel, E.J., and K. Ley. 1996. Distinct phenotype of E-selectin-deficient mice. E-selectin is required for slow leukocyte rolling in vivo. Circ. Res. 79:1196-1204.
11. Jung, U., D.C. Bullard, T.F. Tedder, and K. Ley. 1996. Velocity differences between L-and P-selectin-dependent neutrophil rolling in venules of mouse cremaster muscle in vivo. Am. J. Physiol. 271:H2740-2747.
12. Mayadas, T.N., R.C. Johnson, H. Rayburn, R.O. Hynes, and D.D. Wagner. 1993. Leukocyte rolling and extravasation are severly compromised in P-selectin deficient mice. Cell. 74:541-554.
13. Alon, R., D.A. Hammer, and T.A. Springer. 1995. Lifetime of the P-selectin carbohydrate bond and its response to tensile force in hydrodynamic flow. Nature. 374:539-542.
14. Zimmerman, G.A., S.M. Prescott, and T.M. McIntyre. 1992. Endothelial cell interactions with granulocytes: tethering and signaling molecules, Immunol. Today. 13:93-100.
15. Norton, C.R., J.M. Rumberger, O.K. Burns, and B.A. Wolitzky. 1993. Characterization of murine E-selectin expression in vitro using novel antimouse E-selectin monoclonal antibodies. Biochem. Biophys. Res. Commun. 195:250-258.
16. Pries, A.R. 1988. A versatile video image analysis system for microcirculatory research. Int. J. Microcirc. Clin. Exp. 7:327-345.
17. Lipowsky, H.H., and B.W. Zweifach. 1978. Application of the "two-slit" photometric technique to the measurement of microvascular volumetric flow rates. Microvask. Res. 15:93-101.
18. Reneman, R.S., B. Woldhuis, M.G.A. oude Egbrink, D.W. Slaaf, and G.J. Tangelder. 1992. Concentration and velocity profiles of blood cells in the microcirculation. In Advances in Cardiovascular Engineering. N.H.C. Hwang, editor. 25-40.
19. Zhao, Y.H., S. Chien, and R. Skalak. 1995. A stochastic model of leukocyte rolling. Biophys. J. 69:1309-1320.
20. Kunkel, E.J., U. Jung, D.C. Bullard, K.E, Norman, B.A. Wolitzky, D. Vestweber, A.L. Beaudet, and K. Ley. 1996. Absence of trauma-induced leukocyte rolling in mice deficient in both P-selectin and intercellular adhesion molecule-1 (ICAM-1). J. Exp. Med. 183:57-65.
21. 2integrin avidity in transendothelial chemotaxis of mononuclear cells. J. Immunol. 159:3968-3975.
22. Burns, A.R., D.C. Walker, E.S. Brown, L.T. Thurmon, R.A. Bowden, C.R. Keese, S.I. Simon, M.L. Entman, and C.W. Smith, 1997. Neutrophil transendothelial migration is independent of tight junctions and occurs preferentially at tricellular corners. J. Immunol. 159:2893-2903.
23. Lu, H., C.W. Smith, J. Perrard, D.C. Bullard, L. Tang, S.B. Shappell, M.L. Entman, A.L. Beaudet, and C.M. Ballantyne. 1997. LFA-1 is sufficient in mediating neutrophil emigration in Mac-1-deficient mice. J. Clin. Invest. 99: 1340-1350.
24. Perry, M.A., and D.N. Granger. 1991. Role of CD11/CD18 in shear rate-dependent leukocyte-endothelial cell interactions in cat mesenteric venules. J. Clin. Invest. 87:1798-1804.
25. Lawrence, M.B., C.W. Smith, S.G. Eskin, and L.V. McIntire. 1990. Effect of venous shear stress on CD18-mediated neutrophil adhesion to cultured endothelium. Blood. 75:227-237.
26. Lawrence, M.B., and T.A. Springer. 1991. Leukocytes roll on a selectin at physiologic flow rates: distinction from and prerequisite for adhesion through integrins. Cell. 65:859-873.
27. Damiano, E.R., J. Westheider, A. Tözeren, and K. Ley. 1996. Variation in the velocity, deformation, and adhesion energy density of leukocytes rolling within venules. Circ. Res. 79:1122-1130.
28. Middleton, J., S. Neil, J. Wintle, I. Clark-Lewis, H. Moore, C. Lam, M. Auer, E. Hub, and A. Rot. 1997. Transcytosis and surface presentation of IL-8 by venular endothelial cells. Cell. 91:385-395.
29. Sriramarao, P., U.H. von Andrian, E.C. Butcher, M.A. Bourdon, and D.H. Broide. 1994. L-selectin and very late antigen-4 integrin promote eosinophil rolling at physiological shear rates in vivo. J. Immunol. 153:4238-4246.
30. Huber, A.R., S.L. Kunkel, R.F. Todd III, and S.J. Weiss. 1991. Regulation of transendothelial neutrophil migration by endogenous interleukin-8. Science. 254:99-102.
31. Bussolino, F., G. Camussi, and C. Baglioni. 1988. Synthesis and release of platelet-activating factor by human vascular endothelial cells treated with tumor necrosis factor or interleukin 1 alpha. J. Biol. Chem. 263:11856-11861.
32. Nourshargh, S., S.W. Larkin, A. Das, and T.J. Williams. 1995. Interleukin-1-induced leukocyte extravasation across rat mesenteric microvessels is mediated by platelet-activating factor. Blood. 85:2553-2558.
33. Ley, K., M. Allietta, D.C. Bullard, and S. Morgan. 1998. The importance of E-selectin for firm leukocyte adhesion in vivo. Circ. Res. 83:287-294.
34. Morgan, S.J., M.W. Moore, G. Cacalano, and K. Ley. 1997. Reduced leukocyte adhesion response and absence of slow leukocyte rolling in interleukin-8 receptor-deficient mice. Microvasc. Res. 54:188-191.
35. Gaboury, J.P., and P. Kubes. 1994. Reductions in physiologic shear rates lead to CD11/CD18-dependent, selectin-independent leukocyte rolling in vivo. Blood. 83:345-350.
36. Kansas, G.S. 1996. Selectins and their ligands: current concepts and controversies. Blood. 88:3259-3287.