Biomechanics of cell interactions in shear fields

Advanced Drug Delivery Reviews

Volumn 33, Issue 1-2, 1998, Pages 141-164

  Konstantopoulos, Konstantinos ^a   Kukreti, Sharad ^a   McIntire, Larry V ^a  

^a RICE UNIVERSITY   (United States)

Author keywords

Hematopoiesis; Inflammation; Integrin; Selectin; Shear stress; Signaling; Thrombosis

Indexed keywords

BIOMECHANICS; BLOOD; BLOOD VESSELS; CELLS; FLOW OF FLUIDS; SHEAR STRESS; TISSUE;

CELL INTERACTIONS; THROMBOSIS;

CARDIOVASCULAR SYSTEM;

CELL ADHESION MOLECULE; ENDOTHELIAL LEUKOCYTE ADHESION MOLECULE 1; INTEGRIN; L SELECTIN; PADGEM PROTEIN; SELECTIN;

CELL INTERACTION; CELL MIGRATION; HEMATOPOIESIS; HUMAN; INFLAMMATION; NEUTROPHIL; NONHUMAN; PRIORITY JOURNAL; REVIEW; SHEAR STRESS; THROMBOCYTE ADHESION; THROMBOSIS;

BIOMECHANICS; BLOOD PLATELETS; CELL ADHESION; CELL COMMUNICATION; CELL PHYSIOLOGY; ENDOTHELIUM, VASCULAR; HEMATOPOIESIS; HUMANS; INFLAMMATION; INTEGRINS; LEUKOCYTES; SELECTINS; THROMBOSIS;

EID: 0032479747     PISSN: 0169409X     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0169-409X(98)00024-6     Document Type: Review

References (146)

1. [1] V.T. Turitto, Blood viscosity, mass transport, and thrombogenesis, Prog. Hemost. Thromb. 6 (1982) 139-177.
2. [2] D.A. Jones, C.W. Smith, L.V. McIntire, Flow effects on leukocyte adhesion to vascular endothelium, in: P. Richardson, M. Steiner (Eds.), Principles of Cell Adhesion, CRC Press, Boca Raton, FL, 1995, pp. 143-160.
3. [3] C.F. Dewey Jr., S.R. Bussolari, M.A. Gimbrone Jr., P.F. Davies, The dynamic response of vascular endothelial cells to fluid shear stress, J. Biomed. Eng. 103 (1981) 177-185.
4. [4] G.I. Johnston, A. Kurosky, R.P. McEver, Structural and biosynthetic studies of the granule membrane protein, GMP-140, from human platelets and endothelial cells, J. Biol. Chem. 264 (1989) 1816-1823.
5. [5] P.W. Collins, M.G. Macey, M.R. Cahill, A.C. Newland, Von Willebrand factor release and P-selectin expression is stimulated by thrombin and trypsin but not IL-1 cultured human endothelial cells, Thromb. Haemost. 70 (1993) 346-350.
6. [6] Y. Khew-Goodall, C.M. Butcher, M.S. Litwin, S. Newlands, E.I. Korpelainen, L.M. Noack, M.C. Berndt, A.F. Lopez, J.R. Gamble, M.A. Vadas, Chronic expression of P-selectin on endothelial cell stimulated by the T-cell cytokine, interleukin-3, Blood 87 (1996) 1432-1438.
7. [7] L. Yao, J. Pan, H. Setiadi, K.D. Patel, R.P. McEver, Interleukin 4 or Oncostatin M induces a prolonged increase in P-selectin mRNA and protein in human endothelial cells, J. Exp. Med. 184 (1996) 81-92.
8. [8] F.J. Barkalow, M.J. Goodman, M.E. Gerritsen, T.N. Mayadas, Brain endothelium lack one of two pathways of P-selectin-mediated neutrophil adhesion, Blood 88 (1996) 4585-4593.
9. [9] U. Gotsch, U. Jager, M. Dominis, D. Vestweber, Expression of P-selectin on endothelial cells is upregulated by LPS and TNF-α in vivo, Cell. Adhesion Commun. 2 (1994) 7-14.
10. [10] R.R. Johnson-Tidey, J.L. McGregor, P.R. Taylor, R.N. Poston, Increase in the adhesion molecule P-selectin in endothelium overlying atherosclerosis plaques, Am. J. Pathol. 144 (1994) 952-961.
11. [11] K.D. Patel, K.L. Moore, M.U. Nollert, R.P. McEver, Neutrophils use both shared and distinct mechanisms to adhere to selectins under static and flow conditions, J. Clin. Invest. 96 (1995) 1887-1896.
12. [12] K.L. Moore, N.L. Stults, S. Diaz, D.F. Smith, R.D. Cummings, A. Varki, R.P. McEver, Identification of a specific glycoprotein ligand for P-selectin (CD62) on myeloid cells, J. Cell. Biol. 118 (1992) 445-456.
13. [13] K.L. Moore, K.D. Patel, R.E. Bruehl, F. Li, D.A. Johnson, H.S. Lichenstein, R.D. Cummings, D.F. Bainton, R.P. McEver, P-selectin glycoprotein ligand-1 mediates rolling of human neutrophils on P-selectin, J. Cell. Biol. 128 (1995) 661-671.
14. [14] F. Li, H.P. Erickson, J.A. James, K.L. Moore, R.D. Cummings, R.P. McEver, Visualisation of P-selectin glycoprotein ligand-1 as a highly extended molecule and mapping of protein epitopes for monoclonal antibodies, J. Biol. Chem. 271 (1996) 6342-6348.
15. [15] P.P. Wilkins, R.P. McEver, R.D. Cummings, Structures of the O-glycans on P-selectin glycoprotein ligand-1 from HL-60 cells, J. Biol. Chem. 271 (1996) 18732-18742.
16. [16] D. Sako, K.M. Comess, K.M. Barone, R.T. Camphausen, D.A. Cumming, G.D. Shaw, A sulfated peptide segment at the amino terminus of PSGL-1 is critical for P-selectin binding, Cell 83 (1995) 323-331.
17. [17] J. Kahn, R.H. Ingraham, F. Shirley, G.I. Migkai, T.K. Kishimoto, Membrane proximal cleavage of L-selectin: identification of the cleavage site and a 6-kD transmembrane peptide fragment of L-selectin, J. Cell. Biol. 125 (1994) 461.
18. [18] B.E. Schleiffenbaum, O. Spertini, T.F. Tedder, Soluble L-selectin is present in human plasma at high levels and retains functional activity, J. Cell. Biol. 119 (1992) 229.
19. [19] U.H. von Andrian, S.R. Hasslen, R.D. Nelson, S.L. Erlandsen, E.C. Butcher, A central role for microvillous receptor presentation in leukocyte adhesion under flow, Cell 82 (1995) 989-999.
20. [20] R.C. Fuhlbrigge, R. Alon, K.D. Puri, J.B. Lowe, T.A. Springer, Sialylated, fucosylated ligands for L-selectin expressed on leukocytes mediate tethering and rolling adhesions in physiologic flow conditions, J. Cell. Biol. 135 (1996) 837-848.
21. + hematopoietic cells, J. Cell. Biol. 135 (1996) 523-531.
22. [22] L.J. Picker, R.A. Warnock, A.R. Burns, C.M. Doerschuk, E.L. Berg, E.C. Butcher, The neutrophil selectin LECAM-1 presents carbohydrate ligands to the vascular selectins ELAM-1 and GMP-140, Cell 66 (1991) 921-933.
23. [23] M.P. Bevilacqua, S. Stenglin, M.A.J. Gimbrone, B. Seed, Endothelial leukocyte adhesion molecule 1: an inducible receptor for neutrophils related to complement regulatory proteins and lectins, Science 243 (1989) 1160.
24. [24] P. Ghersa, R.H. van Huijsduijnen, J. Whelan, F. DeLamarter, Labile proteins play a dual role in the control of endothelial leukocyte adhesion molecule-1 (ELAM-1) gene regulation, J. Biol. Chem. 267 (1992) 19226.
25. [25] M. Subramaniam, J.A. Koedam, D.D. Wagner, Divergent fates of P- and E-selectin after their expression on the plasma membrane, Mol. Biol. Cell 4 (1993) 791.
26. [26] L.J. Picker, T.K. Kishimoto, C.W. Smith, R.A. Warnock, E.C. Butcher, ELAM-1 is an adhesion molecule for skin-homing T cells, Nature 349 (1991) 796.
27. x is recognized by the endothelial cell leukocyte adhesion molecule ELAM-1, J. Biol. Chem. 266 (1991) 14869-14872.
28. [28] A. Varki, Selectin ligands, Proc. Natl. Acad. Sci. USA 91 (1994) 7390-7397.
29. [29] M. Steegmaler, A. Levinovitz, S. Isenmann, E. Borges, M. Lenter, H.P. Kocher, B. Kleuser, D. Vestweber, The E-selectin-ligand ESL-1 is a variant of a receptor for fibroblast growth factor, Nature 373 (1995) 615-620.
30. [30] O. Zollner, M.C. Lenter, J.E. Blanks, J.E. Borges, M. Steegmaier, H.G. Zerwes, D. Vestweber, L-selectin from human, but not mouse neutrophils binds directly to E-selectin, J. Cell. Biol. 136 (1997) 707-716.
31. [31] D. Asa, L. Raycroft, L. Ma, P.A. Aeed, P.S. Kaytes, P. Elhammer, J. Geng, The P-selectin glycoprotein ligand functions as a common human leukocyte ligand for P- and E-selectins, J. Biol. Chem. 270 (1995) 11662-11670.
32. [32] K.R. Snapp, A.J. Wagers, R. Craig, L.M. Stoolman, G.S. Kansas, P-selectin glycoprotein ligand-1 is essential for adhesion to P-selectin but not E-selectin in stably transfected hematopoietic cell lines, Blood 89 (1997) 896-901.
33. [33] M.B. Lawrence, G.S. Kansas, E.J. Kunkel, K. Ley, Threshold levels of fluid shear promote leukocyte adhesion through selectins (CD62L, P, E), J. Cell. Biol. 136 (1997) 717-727.
34. [34] L. Phillips, B. Schwartz, A. Etzioni, R. Bayer, H. Ochs, J. Paulson, J. Harlan, Neutrophil adhesion in leukocyte adhesion deficiency syndrome type 2, J. Clin. Invest. 96 (1995) 2898-2906.
35. [35] R.C. Landis, R.I. Bennet, N. Hogg, A novel LFA-1 activation epitope maps to the I domain, J. Cell. Biol. 120 (1993) 1519.
36. 1 integrin-dependent cell adhesion is regulated by a low affinity receptor pool that is conformationally responsive to ligand, J. Cell. Biol. 270 (1995) 28740-28750.
37. [37] Y. Shimizu, G.A. van Seventer, K.J. Horgan, S. Shaw, Regulated expression and binding of three VLA (beta1) integrin receptors on T cells, Nature 345 (1991) 250-253.
38. [38] Y. Shimizu, W. Newman, T.V. Gopal, Four molecular pathways of T-cell adhesion to endothelial cells: roles of LFA-1, VCAM-1, and ELAM-1 and changes in pathway hierarchy under different activation conditions, J. Cell. Biol. 113 (1991) 1203-1212.
39. [39] L.J. Miller, R. Schwarting, T.A. Springer, Regulated expression of the Mac-1, LFA-1, p150,95 glycoprotein family during leukocyte differentiation, J. Immunol. 137 (1986) 2891-2900.
40. [40] G.S. Kansas, M.J. Muirhead, M.O. Dailey, Expression of the CD11/CD18 leukocyte adhesion molecule1, and CD44 adhesion molecules during normal myeloid and erythroid differentiation in humans, Blood 76 (1992) 2483-2492.
41. [41] B.J. Hughes, J.C. Hollers, E. Crockett-Torabi, C.W. Smith, Recruitment of CD11b/CD18 to the neutrophil surface and adherence-dependent cell locomotion, J. Clin. Invest. 90 (1992) 1687-1696.
42. [42] L.J. Miller, D.F. Bainton, N. Borregaard, T.A. Springer, Stimulated mobilization of monocyte Mac-1 and p150,95 adhesion proteins from an intracellular vesicular compartment to the cell surface, J. Clin. Invest. 80 (1987) 535-544.
43. [43] I.I. Singer, S. Scott, D.W. Kawka, D.M. Kazazis, Adhesomes: specific granules containing receptors for laminin, C3bi/ fibrinogen, fibronectin, and vitronectin in human polymorphonuclear leukocytes and monocytes, J. Cell. Biol. 109 (1989) 3169-3182.
44. [44] D.C. Anderson, T.A. Springer, Leukocyte adhesion deficiency: an inherited defect in the Mac-1, LFA-1, and p150,95 glycoproteins, Annu. Rev. Med. 38 (1987) 75-94.
45. [45] T.K. Kishimoto, N. Hollander, T.M. Roberts, D.C. Anderson, T.A. Springer, Heterogeneous mutations in the beta subunit common to the LFA-1, Mac-1, and p150,95 glycoproteins cause leukocyte adhesion deficiency, Cell 50 (1987) 193-202.
46. [46] E.I.B. Peerschke, Platelet membranes and receptors, in: J. Loscalzo, A.I. Schafer (Eds.), Thrombosis and Hemorrhage, Blackwell, Boston, 1994, pp. 219-245.
47. [47] E.U.M. Saelman, H.K. Nieuwenhuis, K.M. Hese, P.G. De-Groot, H.F.G. Heinjnen, E.H. Sage, S. Williams, L. McKeown, H.R. Gralnick, J.J. Sixma, Platelet adhesion to collagen types I-VIII under conditions of stasis and flow is mediated by GPIa/IIa (a2β1-integrin), Blood 85 (1994) 1244-1250.
48. [48] J.M. Ross, L.V. McIntire, Molecular mechanisms of mural thrombosis under dynamic flow conditions, NIPS 10 (1995) 117-122.
49. [49] S.J. Shattil, J.A. Hoxie, M.C. Cunningham, L.F. Brass, Changes in the platelet membrane glycoprotein IIb-IIIa complex during platelet activation, J. Biol. Chem. 260 (1985) 11107-11114.
50. [50] A.L. Frelinger III, S.C.-T. Lam, E.F. Plow, M.A. Smith, J.C. Loftus, M.H. Ginsberg, Occupancy of an adhesive glycoprotein receptor modulates expression of an antigenic site involved in cell adhesion, J. Biol. Chem. 263 (1988) 12397-12402.
51. [51] M.H. Ginsberg, J.C. Loftus, E.F. Plow, Cytoadhesins, integrins, and platelets, Thromb. Haemost. 59 (1988) 1-6.
52. [52] T.N. Zaidi, L.V. McIntire, D.H. Farrell, P. Thiagarajan, Adhesion of platelets to surface-bound fibrinogen under flow, Blood 88 (1996) 2967-2972.
53. [53] L.C. Dunlop, R.K. Andrews, M.C. Berndt, Congenital disorders of platelet function, in: J. Loscalzo, A.I. Schafer (Eds.) Thrombosis and Hemorrhage, Blackwell, Boston, 1994, pp. 615-633.
54. [54] B.R. Alevriadou, J.L. Moake, N.A. Turner, Z.M. Ruggeri, B.J. Folie, M.D. Phillips, A.B. Schreiber, M.E. Hrinda, L.V. McIntire, Real-time analysis of shear dependent thrombus formation and its blockade by inhibitors of von Willebrand factor binding to platelets, Blood 81 (1993) 1263-1276.
55. [55] V.T. Turitto, H.J. Weiss, T.S. Zimmerman, I.I. Sussman, Factor VIII/von Willebrand factor in subendothelium mediates platelet adhesion, Blood 65 (1985) 823-831.
56. [56] K. Konstantopoulos, T.W Chow, N.A. Turner, J.D. Hellums, J.L. Moake, Shear stress-induced binding of von Willebrand factor to platelets, Biorheology 34 (1997) 57-71.
57. [57] J.K. McCrary, L.H. Nolasco, J.D. Hellums, M.H. Kroll, N.A. Turner, J.L. Moake, Direct demonstration of radiolabeled von Willebrand factor binding to platelet glycoprotein Ib and IIb-IIIa in the presence of shear stress, Ann. Biomed. Eng. 23 (1995) 787-793.
58. [58] M. Handa, K. Titani, L.Z. Holland, J.R. Roberts, Z.M. Ruggeri, The von Willebrand factor-binding domain of platelet membrane glycoprotein Ib. Characterization by monoclonal antibodies and partial amino acid sequence analysis of proteolytic fragments, J. Biol. Chem. 261 (1986) 12579-12585.
59. [59] H.J. Weiss, V.T. Turitto, H.R. Baumgartner, Effect of shear rate on platelet interaction with subendothelium in citrated and native blood. I. Shear rate-dependent decrease of adhesion in von Willebrand disease and the Bernard-Soulier syndrome, J. Lab. Clin. Med. 92 (1978) 750-764.
60. [60] T.A. Springer, Traffic signals for lymphocyte recirculation and leukocyte emigration: the multistep paradigm, Cell 76 (1994) 301-314.
61. [61] L. Osborn, C. Vassallo, C.D. Benjamin, Activated endothelium binds lymphocytes through a novel binding site in the alternatively spliced domain of vascular cell adhesion molecule-1, J. Exp. Med. 176 (1992) 99-107.
62. [62] A.A. Vaporciyan, H.M. Delisser, H. Yan, I.I. Mendiguren, S.R. Thorn, M.L. Jones, P.A. Ward, S.M. Albelda, Involvement of platelet-endothelial adhesion molecule-1 in neutrophil recruitment in vivo, Science 262 (1993) 1580-1582.
63. [63] Y. Tanaka, S.M. Albelda, K.J. Horgan, CD31 expressed on distinctive T cell subsets is a preferential amplifier of beta 1 integrin-mediated adhesion, J. Exp. Med. 176 (1992) 245-253.
64. [64] K. Konstantopoulos, L.V. McIntire, Effects of fluid dynamic forces on vascular cell adhesion, J. Clin. Invest. 98 (1996) 2661-2665.
65. [65] M.B. Lawrence, T.A. Springer, Leukocyte roll on a selectin at physiologic flow rates: distinction from and prerequisite for adhesion through integrins, Cell 65 (1991) 859-873.
66. [66] C.W. Smith, Endothelial adhesion molecules and their roles in inflammation, Can. J. Physiol. Pharmacol. 71 (1993) 76-87.
67. [67] W.A. Muller, S.A. Weigl, X. Deng, D.M. Phillips, PECAM-1 is required for transendothelial migration of leukocytes, J. Exp. Med. 178 (1993) 449-460.
68. [68] U.H. von Andrian, E.M. Berger, J.D. Chambers, L. Ramezani, H. Ochs, J.M. Harlan, J.D. Paulson, A. Etzioni, K.E. Arfors, In vivo behavior of neutrophils from two patients with distinct inherited leukocyte deficiency syndromes, J. Clin. Invest. 91 (1993) 2893-2897.
69. [69] M.B. Lawrence, L.V. McIntire, S.G. Eskin, Effect of flow on polymorphonuclear leukocyte/endothelial cell adhesion, Blood 70 (1987) 1284-1291.
70. [70] M.B. Lawrence, C.W. Smith, S.G. Eskin, L.V. McIntire, Effect of venous shear stress on CD18-mediated neutrophil adhesion to cultured endothelium, Blood 75 (1990) 227-236.
71. [71] K. Ley, D.C. Bullard, M.L. Arbones, R. Bosse, D. Vestweber, T.F. Tedder, A.L. Beaudet, Sequential contribution of L- and P-selectin to leukocyte rolling in vivo, J. Exp. Med. 181 (1995) 669-675.
72. [72] M.A. Labow, C.R. Norton, J.M. Rumberger, K.M. Lombard-Gillooly, D.J. Shuster, J. Hubbard, R. Bertko, P.A. Knaack, R.W. Terry, M.L. Harbison, F. Kontgen, C.L. Stewart, K.W. McIntyre, P.C. Will, D.K. Burns, B.A. Wolitzky, Characterization of E-selectin-deficient mice: demonstration of overlapping function of the endothelial selectins, Immunity 1 (1994) 709-720.
73. [73] U.H. von Andrian, J.D. Chambers, L. McEvoy, R.F. Bargatze, K.E. Arfors, E.C. Butcher, Two-step model of leukocyte-endothelial cell interaction in inflammation: distinct roles for LECAM-1 and the leukocyte β2 integrins in vivo, Proc. Natl. Acad. Sci. USA 88 (1991) 7538-7542.
74. [74] T.F. Tedder, D.A. Steeber, P. Pizcueta, L-selectin-deficient mice have impaired leukocyte recruitment into inflammatory sites, J. Exp. Med. 181 (1995) 2259-2264.
75. [75] O. Abbassi, T.K. Kishimoto, L.V. McIntire, D.C. Anderson, C.W. Smith, E-selectin supports neutrophil rolling in vitro under conditions of flow, J. Clin. Invest. 92 (1993) 2719-2730.
76. [76] D.A. Jones, C.W. Smith, L.J. Picker, L.V. McIntire, Neutrophil adhesion to 24-hour IL-1-stimulated endothelial cells under flow conditions, J. Immunol. 157 (1996) 858-863.
77. [77] D.A. Jones, O. Abbassi, L.V. McIntire, R.P. McEver, C.W. Smith, P-selectin mediates neutrophil rolling on histamine-stimulated endothelial cells, Biophys. J. 65 (1993) 1560-1569.
78. [78] M.B. Lawrence, T.A. Springer, Neutrophils roll on E-selectin, J. Immunol. 151 (1993) 6338-6346.
79. [79] M.B. Lawrence, E.L. Berg, E.C. Butcher, T.A. Springer, Rolling of lymphocytes and neutrophils on peripheral node addressin and subsequent arrest on ICAM-1 in shear flow, Eur. J. Immunol. 25 (1995) 1025-1031.
80. [80] M.B. Lawrence, D.F. Bainton, T.A. Springer, Neutrophil tethering to and rolling on E-selectin are separable by the requirement for L-selectin, Immunity 1 (1994) 137-145.
81. [81] R.F. Bargatze, S. Kurk, E.C. Butcher, M.A. Jutila, Neutrophils roll on adherent neutrophils bound to cytokine-induced endothelial cells via L-selectin on the rolling cells, J. Exp. Med. 180 (1994) 1785-1792.
82. [82] B. Walcheck, K.L. Moore, R.P. McEver, T.K. Kishimoto, Neutrophil-neutrophil interactions under hydrodynamic shear stress involve L-selectin and PSGL-1. A mechanism that amplifies initial leukocyte accumulation on P-selectin in vitro, J. Clin. Invest. 98 (1996) 1081-1087.
83. [83] R. Alon, R.C. Fuhlbrigge, E.B. Finger, T.A. Springer, Interactions through L-selectin between leukocytes and adherent leukocytes nucleate rolling adhesions on selectins and VCAM-1 in shear flow, J. Cell. Biol. 135 (1996) 849-865.
84. [84] D.A. Jones, L.V. McIntire, C.W. Smith, L.J. Picker, A two-step adhesion cascade for T cell/endothelial cell interactions under flow conditions. J. Clin. Invest. 94 (1994) 2443-2450.
85. [85] R. Alon, P.D. Kassner, M.W. Carr, E.B. Finger, M.E. Helmer, T.A. Springer, The integrin-VLA-4 supports tethering and rolling in flow on VCAM-1, J. Cell. Biol. 128 (1995) 1243-1253.
86. [86] K. Konstantopoulos, S. Kukreti, C.W. Smith, L.V. McIntire, Endothelial P-selectin and VCAM-1 each can function as primary adhesive mechanisms for T cells under conditions of flow, J. Leuk. Biol. 61 (1997) 179-187.
87. [87] Y. Abe, C.M. Ballantyne, C.W. Smith, Functions of domain 1 and 4 of vascular cell adhesion molecule-1 in α4 integrin-dependent adhesion under static and flow conditions are differentially regulated, J. Immunol. 157 (1996) 5061-5069.
88. [88] C. Berlin, R.F. Bargatze, J.J. Campbell, U.H. von Andrian, M.C. Szabo, S.R. Hasslen, R.D. Nelson, E.L. Berg, S.L. Erlandsen, E.C. Butcher, α4 integrins mediate lymphocyte attachment and rolling under physiologic flow, Cell 80 (1995) 413-422.
89. [89] S. Kukreti, K. Konstantopoulos, C.W. Smith, L.V. McIntire, Molecular mechanisms of monocyte adhesion to IL-1 β stimulated endothelial cells under physiological flow conditions, Blood 89 (1997) 4104-4111.
90. [90] K. Ley, Histamine can induce leukocyte rolling in rat mesenteric venules, Am. J. Physiol. 267 (1994) H1017-H1023.
91. 4-integrin supports leukocyte rolling and adhesion in chronically inflamed postcapillary venules in vivo, J. Exp. Med. 183 (1996) 1995-2006.
92. [92] M.W. Wakelin, M.-J. Sanz, A. Dewar, S.M. Albelda, S.W. Larkin, N. Boughton-Smith, T.J. Williams, S. Nourshargh, An anti-platelet-endothelial cell adhesion molecule-1 antibody inhibits leukocyte extravasation from mesenteric microvessels in vivo by blocking the passage through the basement membrane, J. Exp. Med. 184 (1996) 229-241.
93. [93] E.J. Kunkel, U. Jung, D.C. Bullard, K.E. Norman, B.A. Wolitzky, D. Vestweber, A.L. Beaudet, K. Ley, Absence of trauma-induced leukocyte rolling in mice deficient in both P-selectin and intracellular adhesion molecule 1, J. Exp. Med. 183 (1996) 57-65.
94. [94] K.D. Patel, M.U. Nollert, R.P. McEver, P-selectin must extend a sufficient length from the plasma membrane to mediate rolling of neutrophil, J. Cell. Biol. 131 (1995) 1893-1902.
95. [95] R. Alon, D.A. Hammer, T.A. Springer, Lifetime of the P-selectin-carbohydrate bond and its response to tensile force in hydrodynamic flow, Nature 374 (1995) 539-542.
96. [96] L.A. Tempelman, D.A. Hammer, Receptor-mediated binding of IgE-sensitized rat basophilic leukemia cells to antigen-coated substrates under hydrodynamic flow, Biophys. J. 66 (1994) 1231-1243.
97. [97] K.D. Puri, E.B. Finger, T.A. Springer, The faster kinetics of L-selectin than of E-selectin and P-selectin rolling at comparable binding strength, J. Immunol. 158 (1997) 405-413.
98. [98] D.E. Lorant, R.P. McEver, T.M. McIntyre, K.L. Moore, S.M. Prescott, G.A. Zimmerman, Activation of polymorphonuclear leukocytes reduces their adhesion to P-selectin and causes redistribution of ligands for P-selectin on their surfaces, J. Clin. Invest. 96 (1995) 171-182.
99. [99] M.A. Jutila, L. Rott, E.L. Berg, E.C. Butcher, Function and regulation of neutrophil MEL-14 antigen in vivo: comparison with LFA-1 and Mac-1, J. Immunol. 143 (1989) 3318-3324.
100. [100] T.A. Springer, Traffic signals on endothelium for lymphocyte recirculation and leukocyte emigration, Annu. Rev. Physiol. 57 (1995) 827-872.
101. [101] T.K. Waddell, L. Fialkow, C.K. Chan, T.K. Kishimoto, G.P. Downey, Potentiation of the oxidative burst of human neutrophils. A signalling role for L-selectin, J. Biol. Chem. 269 (1994) 18485-18491.
102. [102] T.K. Waddell, L. Fialkow, C.K. Chan, T.K. Kishimoto, G.P. Downey, Signaling functions of L-selectin: enhancement of tyrosine phosphorylation and activation of MAP kinase, J. Biol. Chem. 270 (1995) 15403-15411.
103. [103] S.I. Simon, A.R. Burns, A.D. Taylor, P.K. Gopalan, E.B. Lynam, L.A. Sklar, C.W. Smith, L-selectin (CD62L) cross-linking signals neutrophil adhesive functions via the Mac-1 (CD11b/CD18) β2 integrin, J. Immunol. 155 (1995) 1502-1514.
104. [104] P.K. Gopalan, C.W. Smith, H. Lu, E.L. Berg, L.V. McIntire, S.I. Simon, Neutrophil CD18-dependent arrest on intercellular adhesion molecule 1 (ICAM-1) in shear flow can be activated through L-selectin, J. Immunol. 158 (1997) 367-375.
105. [105] S.T. Hwang, M.S. Singer, P.A. Giblin, T. Yednock, K.B. Bacon, S.I. Simon, S.D. Rosen, GlyCAM-1, a physiologic ligand for L-selectin, activates β2 integrins on naive peripheral lymphocytes, J. Exp. Med. 184 (1996) 1343-1348.
106. [106] K. Nagata, T. Tsuji, N. Todoroki, Y. Katagiri, K. Tanoue, H. Yamazaki, N. Hanai, T. Irimura, Activated platelets induce superoxide anion release by monocytes and neutrophils through P-selectin (CD62), J. Immunol. 151 (1993) 3267-3273.
107. [107] M.R. Elstad, T.R. La Pine, F.S. Cowley, R.P. McEver, T.M. McIntyre, S.M. Prescott, G.A. Zimmerman, P-selectin regulates platelet-activating factor synthesis and phagocytosis by monocytes, J. Immunol. 155 (1995) 2109-2122.
108. [108] A.S. Weyrich, M.R. Elstad, R.P. McEver, T.M. McIntyre, K.L. Moore, J.H. Morrissey, S.M. Prescott, G.A. Zimmerman, Activated platelets signal chemokine synthesis by human monocytes, J. Clin. Invest. 97 (1996) 1525-1534.
109. [109] D. Cooper, C.M. Butcher, M.C. Berndt, M.A. Vadas, P-selectin interacts with a β2-integrin to enhance phagocytosis, J. Immunol. 153 (1994) 3199-3209.
110. [110] D.E. Lorant, M.K. Topham, R.E. Whatley, R.P. McEver, T.M. McIntyre, S.M. Prescott, G.A. Zimmerman, Inflammatory roles of P-selectin, J. Clin. Invest. 92 (1993) 559-570.
111. [111] S.K. Lo, S. Lee, R.A. Ramos, R. Lobb, M. Rosa, G. Chi-Ross, S.D. Wright, Endothelial-leukocyte adhesion molecule1 stimulates the adhesive activity of leukocyte integrin CR3 (CD11b/CD18, Mac-1) on human neutrophils, J. Exp. Med. 173 (1991) 1493-1500.
112. [112] J.M. Ross, L.V. McIntire, J.L. Moake, J.H. Rand, Platelet adhesion and aggregation on human type VI collagen surfaces under physiological flow conditions, Blood 85 (1995) 1826-1835.
113. [113] B. Savage, E. Saldivar, Z.M. Ruggeri, Initiation of platelet adhesion by arrest onto fibrinogen or translocation on von Willebrand factor, Cell 84 (1996) 289-297.
114. [114] L.V. McIntire, 1992 ALZA Distinguished Lecture: bioengineering and vascular biology, Ann. Biomed. Eng. 22 (1994) 2-13.
115. [115] Z.M. Ruggeri, von Willebrand factor, J. Clin. Invest. 99 (1997) 559-564.
116. [116] C.H. Brown, L.B. Leverett, C.W Lewis, C.P. Alfrey, J.D. Hellums, Morphological, biochemical and functional changes in human platelets subjected to shear stress, J. Lab. Clin. Med. 86 (1975) 462-471.
117. [117] Y. Ikeda, M. Handa, K. Kawano, T. Kamata, M. Murata, Y. Araki, H. Anbo, Y. Kawai, K. Watanabe, I. Itagaki, K. Sakai, Z.M. Ruggeri, The role of von Willebrand factor and fibrinogen in platelet aggregation under varying shear stress, J. Clin. Invest. 87 (1991) 1234-1240.
118. [118] J.L. Moake, N.A. Turner, N.A. Stathopoulos, L.H. Nolasco, J.D. Hellums, Involvement of large plasma von Willebrand factor multimers and unusually large vWF forms derived from endothelial cells in shear stress-induced platelet aggregation, J. Clin. Invest. 78 (1986) 1456-1461.
119. [119] J.L. Moake, N.A. Turner, N.A. Stathopoulos, L.H. Nolasco, J.D. Hellums, Shear-induced platelet aggregation can be mediated by vWF released from platelets, as well as by exogenous large or unusually large vWF multimers, requires adenosine diphosphate, and is resistant to aspirin, Blood 71 (1988) 1366-1374.
120. [120] D.M. Peterson, N.A. Stathopoulos, T.D. Giorgio, J.D. Hellums, J.L. Moake, Shear-induced platelet aggregation requires von Willebrand factor and platelet membrane glycoproteins Ib and IIb-IIIa, Blood 69 (1987) 625-628.
121. [121] K. Konstantopoulos, K.K. Wu, M.M. Udden, E.I. Bañez, S.J. Shattil, J.D. Hellums, Flow cytometric studies of platelet responses to shear stress in whole blood, Biorheology 32 (1995) 73-93.
122. 3, Thromb. Haemost. 78 (1997) 220-225.
123. [123] S.J. Shattil, M.H. Ginsberg, Integrin signaling in vascular biology, J. Clin. Invest. 100 (1997) 1-5.
124. [124] R.J. Faull, M.H. Ginsberg, Inside-out signaling through integrins, J. Am. Soc. Nephrol. 7 (1996) 1091-1097.
125. [125] S.J. Shattil, M.H. Ginsberg, J.S. Brugge, Adhesive signaling in platelets, Cur. Opin. Cell. Biol. 6 (1994) 695-705.
126. [126] T.W. Chow, J.D. Hellums, J.L. Moake, M.H. Kroll, Shear stress-induced von Willebrand factor binding to platelet glycoprotein Ib initiates calcium influx associated with aggregation, Blood 80 (1992) 113-120.
127. [127] Y. Ikeda, M. Handa, T. Kamata, K. Kawano, Y. Kawai, K. Watanabe, K. Kawakami, K. Sakai, M. Fukuyama, I. Itagaki, A. Yoshioka, Z.M. Ruggeri, Transmembrane calcium influx associated with von Willebrand factor binding to GPIb in the initiation of shear-induced platelet aggregation, Thromb. Haemost. 69 (1993) 496-502.
128. [128] M.H. Kroll, J.D. Hellums, L.V. McIntire, A.I. Schafer, J.L. Moake, Platelets and shear stress, Blood 88 (1996) 1525-1541.
129. [129] M.D. Allen, T.O. McDonald, V.E. Himes, D.P. Fishbein, S. Aziz, D.D. Reichenbach, E-selectin expression in human cardiac grafts with cellular rejection, Circulation 88 (1993) 243-247.
130. [130] D.M. Briscoe, R.S. Cotran, Role of leukocyte-endothelial cell adhesion molecules in renal inflammation: in vitro and in vivo studies, Kidney Int. 44 (1993) S27-S34.
131. [131] H.A.A. Rabb, Cell adhesion molecules and the kidney, Am. J. Kidney Dis. 23 (1994) 155-166.
132. [132] M. Isobe, H. Yagita, K. Okumura, A. Ihara, Specific acceptance of cardiac allograft after treatment with antibodies to ICAM-1 and LFA-1, Science 255 (1992) 1125-1127.
133. [133] M. Isobe, A. Ihara, Tolerance induction against cardiac allograft by anti-ICAM-1 and LFA-1 treatment: T cells respond to in vitro allostimulation, Transplant Proc. 25 (1993) 1079-1080.
134. [134] C.H. Gemmell, S.M. Ramirez, E.L. Yeo, M.v. Sefton, Platelet activation in whole blood by artificial surfaces: identification of platelet-derived microparticles and activated platelet binding to leukocytes as material-induced activation events, J. Lab. Clin. Med. 125 (1995) 276-287.
135. [135] B.J. Folie, L.V. McIntire, Mathematical analysis of mural thrombosis: concentration profiles of platelet-activating agents and effects of viscous shear flow, Biophys. J. 56 (1989) 1393-1400.
136. [136] H. Matsuno, O. Kozawa, M. Niwa, T. Uematsu, Inhibition of von Willebrand factor binding to platelet GPIb by a fractionated autotricarboxylic acid prevents restenosis after vascular injury in hamster carotid artery, Circulation 96 (1997) 1299-1305.
137. [137] The EPIC investigators, Use of a monoclonal antibody directed against the platelet glycoprotein IIb/IIIa receptor in high-risk coronary angioplasty, N. Engl. J. Med. 330 (1994) 956-961.
138. [138] K. Konstantopoulos, S.G. Kamat, A.I. Schafer, E.I. Bañez, R. Jordan, N.S. Kleiman, J.D. Hellums, Shear-induced platelet aggregation is inhibited by in vivo infusion of an anti-glycoprotein IIb/IIIa antibody fragment, c7E3 Fab, in patients undergoing coronary angioplasty, Circulation 91 (1995) 1427-1431.
139. [139] N.A. Turner, J.L. Moake, S.G. Kamat, A.I. Schafer, N.S. Kleiman, R. Jordan, L.V. McIntire, Comparative real-time effects on platelet adhesion and aggregation under flowing conditions of in vivo aspirin, heparin, and monoclonal antibody fragment against glycoprotein IIb-IIIa, Circulation 91 (1995) 1354-1362.
140. [140] S.G. Kamat, N.A. Turner, K. Konstantopoulos, J.D. Hellums, L.V. McIntire, N.S. Kleiman, J.L. Moake, Effects of integrelin on platelet function in flow models of arterial thrombosis, J. Cardiovasc. Pharmacol. 29 (1997) 156-163.
141. [141] M.R. Koller, J.G. Bender, W.M. Miller, E.T. Papoutsakis, Expansion of primitive human hematopoietic progenitors in a perfusion bioreactor system with IL-3, IL-6, and stem cell factor, Biotechnology 11 (1993) 358-363.
142. [142] M. Koller, S. Emerson, B. Palsson, Large-scale expansion of human stem and progenitor cells from bone marrow mononuclear cells in continuous perfusion cultures, Blood 82 (1993) 378-384.
143. [143] C.E. Sandstrom, J.G. Bender, E.T. Papoutsakis, W.M. Miller, Effects of CD34 cell secretion and perfusion on ex vivo expansion of peripheral blood mononuclear cells, Blood 86 (1995) 958-970.
144. [144] C.E. Sandstrom, J.G. Bender, W.M. Miller, E.T. Papoutsakis, Development of novel perfusion chamber to retain nonadherent cells and its use for comparison of human mobilized peripheral blood mononuclear cell cultures with and without irradiated bone marrow stroma, Biotech. Bioeng. 50 (1996) 493-504.
145. [145] C.W Patrick, T.W. Smith, L.V. McIntire, H.S. Juneja, Cellular interactions among marrow stromal and normal/ neoplastic pre-B- and B-lymphoblastic cells, Leuk. Lymph. 22 (1996) 205-219.
146. [146] C.W. Patrick, H.S. Juneja, S. Lee, F.C. Schmalstieg, L.V. McIntire, Heterotypic adherence between human B-lymphoblastic and pre-B-lymphoblastic cells and marrow stromal cells is a biphasic event: integrin very late antigen-4α mediates only the early phase of the heterotypic adhesion, Blood 85 (1995) 168-178.