Electrophysiological properties of two axonal sodium channels, Nav1.2 and Nav1.6, expressed in mouse spinal sensory neurones

Journal of Physiology

Volumn 564, Issue 3, 2005, Pages 803-815

  Rush, Anthony M ^a,b   Dib Hajj, Sulayman D ^a,b   Waxman, Stephen G ^a,b  

^a YALE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b VA CONNECTICUT HEALTHCARE SYSTEM   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CALCIUM ION; SODIUM CALCIUM EXCHANGE PROTEIN; SODIUM CHANNEL; SODIUM ION;

ANIMAL CELL; ARTICLE; AXONAL INJURY; DEMYELINATION; ELECTROPHYSIOLOGY; MALE; MAMMAL CELL; MOUSE; NERVE CELL EXCITABILITY; NERVE CELL MEMBRANE POTENTIAL; NONHUMAN; PRIORITY JOURNAL; PROTEIN LOCALIZATION; SENSORY NERVE CELL; SODIUM CALCIUM EXCHANGE; SODIUM CHANNEL 1.2; SODIUM CHANNEL 1.6; SODIUM CURRENT; SPINAL CORD NERVE CELL;

ACTION POTENTIALS; ANIMALS; AXONS; CELLS, CULTURED; GANGLIA, SPINAL; ION CHANNEL GATING; MALE; MEMBRANE POTENTIALS; MICE; NERVE TISSUE PROTEINS; NEURONS, AFFERENT; RECOMBINANT PROTEINS; SODIUM CHANNELS;

EID: 18944369617     PISSN: 00223751     EISSN: None     Source Type: Journal    
DOI: 10.1113/jphysiol.2005.083089     Document Type: Article

References (46)

1. Afshari FS, Ptak K, Khaliq ZM, Grieco TM, Slater NT, McCrimmon DR & Raman IM (2004). Resurgent Na currents in four classes of neurons of the cerebellum. J Neurophysiol 92, 2831-2843.
2. Akopian AN, Souslova V, England S, Okuse K, Ogata N, Ure J, Smith A, Kerr BJ, McMahon SB, Boyce S, Hill R, Stanfa LC, Dickenson AH & Wood JN (1999). The tetrodotoxin-resistant sodium channel SNS has a specialized function in pain pathways. Nat Neurosci 2, 541-548.
3. Baker MD & Bostock H (1997). Low-threshold, persistent sodium current in rat large dorsal root ganglion neurons in culture. J Neurophysiol 77, 1503-1513.
4. Black JA, Dib-Hajj S, McNabola K, Jeste S, Rizzo MA, Kocsis JD & Waxman SG (1996). Spinal sensory neurons express multiple sodium channel alpha-subunit mRNAs. Mol Brain Res 43, 117-131.
5. v1.6 is expressed along nonmyelinated axons and it contributes to conduction. Mol Brain Res 105, 19-28.
6. Boiko T, Rasband MN, Levinson SR, Caldwell JH, Mandel G, Trimmer JS & Matthews G (2001). Compact myelin dictates the differential targeting of two sodium channel isoforms in the same axon. Neuron 30, 91-104.
7. v1.6. Voltage-gated sodium channel from human brain. Mol Brain Res 103, 80-90.
8. Caffrey JM, Eng DL, Black JA, Waxman SG & Kocsis JD (1992). Three types of sodium channels in adult rat dorsal root ganglion neurons. Brain Res 592, 283-297.
9. Chahine M, George AL Jr, Zhou M, Ji S, Sun W, Barchi RL & Horn R (1994). Sodium channel mutations in paramyotonia congenita uncouple inactivation from activation. Neuron 12, 281-294.
10. v1.6 and the sodium-calcium exchanger at sites of axonal injury in the spinal cord in EAE. Brain 127, 294-303.
11. Craner MJ, Lo AC, Black JA & Waxman SG (2003). Abnormal sodium channel distribution in optic nerve axons in a model of inflammatory demyelination. Brain 126, 1552-1561.
12. 2+ exchanger. Proc Natl Acad Sci U S A 101, 8168-8173.
13. v1.3 sodium channels: rapid repriming and slow closed-state inactivation display quantitative differences after expression in a mammalian cell line and in spinal sensory neurons. J Neurosci 21, 5952-5961.
14. Cummins TR, Dib-Hajj SD, Black JA, Akopian AN, Wood JN & Waxman SG (1999). A novel persistent tetrodotoxin-resistant sodium current in SNS-null and wild-type small primary sensory neurons. J Neurosci 19, RC43.
15. v1.6 sodium channels generate resurgent current in primary sensory neurons. Program No. 8.7 2003 Abstract Viewer/Itinerary Planner. Society for Neuroscience, Washington, DC.
16. Cummins TR, Howe JR & Waxman SG (1998). Slow closed-state inactivation: a novel mechanism underlying ramp currents in cells expressing the hNE/PN1 sodium channel. J Neurosci 18, 9607-9619.
17. Cummins TR & Waxman SG (1997). Downregulation of tetrodotoxin-resistant sodium currents and upregulation of a rapidly repriming tetrodotoxin-sensitive sodium current in small spinal sensory neurons after nerve injury. J Neurosci 17, 3503-3514.
18. v1.6-null mice. J Neurophysiol 92, 726-733.
19. Elliott AA & Elliott JR (1993). Characterization of TTX-sensitive and TTX-resistant sodium currents in small cells from adult rat dorsal root ganglia. J Physiol 463, 39-56.
20. Everill B, Cummins TR, Waxman SG & Kocsis JD (2001). Sodium currents of large (A beta-type) adult cutaneous afferent dorsal root ganglion neurons display rapid recovery from inactivation before and after axotomy. Neuroscience 106, 161-169.
21. Goldin AL, Barchi RL, Caldwell JH, Hofmann F, Howe JR, Hunter JC, Kallen RG, Mandel G, Meisler MH, Netter YB, Noda M, Tamkun MM, Waxman SG, Wood JN & Catterall WA (2000). Nomenclature of voltage-gated sodium channels. Neuron 28, 365-368.
22. Grieco TM, Afshari FS & Raman IM (2002). A role for phosphorylation in the maintenance of resurgent sodium current in cerebellar purkinje neurons. J Neurosci 22, 3100-3107.
23. Grieco TM, Malhotra JD, Chen C, Isom LL & Raman IM (2005). Open-channel block by the cytoplasmic tail of sodium channel β4 as a mechanism for resurgent sodium current. Neuron 45, 233-244.
24. v1.6-null Purkinje neurons by slowing sodium channel inactivation with β-pompilidotoxin. J Neurosci 24, 35-42.
25. v1.7 sodium channels in mouse spinal sensory neurons. J Physiol 551, 741-750.
26. Isom LL, De Jongh KS & Catterall WA (1994). Auxiliary subunits of voltage-gated ion channels. Neuron 12, 1183-1194.
27. v1.6 at developing CNS nodes of Ranvier. Neuron 30, 105-119.
28. Kearney JA, Plummer NW, Smith MR, Kapur J, Cummins TR, Waxman SG, Goldin AL & Meisler MH (2001). A gain-of-function mutation in the sodium channel gene Scn2a results in seizures and behavioral abnormalities. Neuroscience 102, 307-317.
29. Khaliq ZM, Gouwens NW & Raman IM (2003). The contribution of resurgent sodium current to high-frequency firing in Purkinje neurons: an experimental and modeling study. J Neurosci 23, 4899-4912.
30. Klugbauer N, Lacinova L, Flockerzi V & Hofmann F (1995). Structure and functional expression of a new member of the tetrodotoxin-sensitive voltage-activated sodium channel family from human neuroendocrine cells. EMBO J 14, 1084-1090.
31. Ma JY, Catterall WA & Scheuer T (1997). Persistent sodium currents through brain sodium channels induced by G protein βγ subunits. Neuron 19, 443-452.
32. O'Leary ME (1998). Characterization of the isoform-specific differences in the gating of neuronal and muscle sodium channels. Can J Physiol Pharmacol 76, 1041-1050.
33. Pan F & Beam KG (1999). The absence of resurgent sodium current in mouse spinal neurons. Brain Res 849, 162-168.
34. Raman IM & Bean BP (1997). Resurgent sodium current and action potential formation in dissociated cerebellar purkinje neurons. J Neurosci 17, 4517-4526.
35. Raman IM, Sprunger LK, Meisler MH & Bean BP (1997). Altered subthreshold sodium currents and disrupted firing patterns in Purkinje neurons of Scn8a mutant mice. Neuron 19, 881-891.
36. Rush AM, Brau ME, Elliott AA & Elliott JR (1998). Electrophysiological properties of sodium current subtypes in small cells from adult rat dorsal root ganglia. J Physiol 511, 771-789.
37. Smith MR, Smith RD, Plummer NW, Meisler MH & Goldin AL (1998). Functional analysis of the mouse Scn8a sodium channel. J Neurosci 18, 6093-6102.
38. + conductance in rat optic nerve axons. Proc Natl Acad Sci U S A 90, 6976-6980.
39. 2+ exchanger. J Neurosci 12, 430-439.
40. Swensen AM & Bean BP (2003). Ionic mechanisms of burst firing in dissociated Purkinje neurons. J Neurosci 23, 9650-9663.
41. Waxman SG, Davis PK, Black JA & Ransom BR (1990). Anoxic injury of mammalian central white matter: decreased susceptibility in myelin-deficient optic nerve. Ann Neurol 28, 335-340.
42. Wellmann H, Kaltschmidt B & Kaltschmidt C (1999). Optimized protocol for biolistic transfection of brain slices and dissociated cultured neurons with a hand-held gene gun. J Neurosci Meth 92, 55-64.
43. + channel subtypes in central neurons. Neuron 3, 695-704.
44. + channel expressed in a stable mammalian cell line. Pflugers Arch 441, 425-433.
45. Yu FH, Westenbroek RE, Silos-Santiago I, McCormick KA, Lawson D, Ge P, Ferriera H, Lilly J, DiStefano PS, Catterall WA, Scheuer T & Curtis R (2003). Sodium channel β4, a new disulfide-linked auxiliary subunit with similarity to β2. J Neurosci 23, 7577-7585.
46. v1.6 sodium channel. Biophys J 87, 3862-3872.