Cardioprotection of the aged rat heart by GSK-3β inhibitor is attenuated: Age-related changes in mitochondrial permeability transition pore modulation

American Journal of Physiology - Heart and Circulatory Physiology

Volumn 300, Issue 3, 2011, Pages

  Zhu, Jiang ^a   Rebecchi, Mario J ^a   Glass, Peter S A ^a   Brink, Peter R ^a   Liu, Lixin ^a  

^a STONY BROOK UNIVERSITY   (United States)

Author keywords

Aging heart; Ischemia reperfusion injury; Mitochondrial permeability transition pore; SB 216763

Indexed keywords

1,2,3,6 TETRAHYDRO 1 METHYL 4 PHENYLPYRIDINE; 2 (2,4 DICHLOROPHENYL) 3 (1 METHYL 3 INDOLYL)MALEIMIDE; GLYCOGEN SYNTHASE KINASE 3BETA; MITOCHONDRIAL PERMEABILITY TRANSITION PORE; NICOTINAMIDE ADENINE DINUCLEOTIDE; REACTIVE OXYGEN METABOLITE;

AGING; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONFOCAL MICROSCOPY; CONTROLLED STUDY; ENZYME PHOSPHORYLATION; FISCHER 344 RAT; HEART INFARCTION; HEART INFARCTION SIZE; HEART MUSCLE; HEART MUSCLE CELL; HEART MUSCLE ISCHEMIA; HEART MUSCLE REPERFUSION; HEART PROTECTION; IMMUNOBLOTTING; IN VIVO STUDY; MALE; MITOCHONDRIAL PERMEABILITY; NONHUMAN; OXIDATIVE STRESS; PRIORITY JOURNAL; RAT; REPERFUSION INJURY;

AGING; ANIMALS; GLYCOGEN SYNTHASE KINASE 3; HEART; INDOLES; MALE; MALEIMIDES; MITOCHONDRIAL MEMBRANE TRANSPORT PROTEINS; MYOCARDIAL INFARCTION; MYOCARDIAL REPERFUSION INJURY; MYOCARDIUM; MYOCYTES, CARDIAC; NAD; RATS; RATS, INBRED F344; REACTIVE OXYGEN SPECIES;

EID: 79955072852     PISSN: 03636135     EISSN: 15221539     Source Type: Journal    
DOI: 10.1152/ajpheart.00860.2010     Document Type: Article

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