A fission yeast homolog of Int-6, the mammalian oncoprotein and eIF3 subunit, induces drug resistance when overexpressed

Molecular Biology of the Cell

Volumn 11, Issue 11, 2000, Pages 3993-4003

  Crane, R ^a   Craig, R ^a   Murray, R ^a   Dunand Sauthier, I ^a   Humphrey, T ^a   Norbury, C ^a  

^a UNIVERSITY OF OXFORD   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

INITIATION FACTOR 3; MESSENGER RNA; ONCOPROTEIN; PROTEIN INT 6; TRANSCRIPTION FACTOR AP 1; UNCLASSIFIED DRUG;

ALLELE; ANIMAL CELL; ARTICLE; CARBOXY TERMINAL SEQUENCE; CARCINOGENESIS; CONTROLLED STUDY; GENE EXPRESSION; GROWTH RETARDATION; MOUSE MAMMARY TUMOR ONCOVIRUS; MULTIDRUG RESISTANCE; NONHUMAN; PRIORITY JOURNAL; RAT; TRANSLATION INITIATION; YEAST CELL;

ANIMALIA; MAMMALIA; MAMMARY TUMOR ONCOVIRUS; MAMMARY TUMOR VIRUS; MOUSE MAMMARY TUMOR VIRUS; MURINAE; ONCOVIRINAE; SCHIZOSACCHAROMYCES POMBE; TUMOR VIRUS;

EID: 0033749641     PISSN: 10591524     EISSN: None     Source Type: Journal    
DOI: 10.1091/mbc.11.11.3993     Document Type: Article

References (39)

1. Conservation and diversity of eukaryotic translation initiation factor eIF3
2. The translation initiation factor eIF3-p48 subunit is encoded by int-6, a site of frequent integration by the mouse mammary tumor virus genome
3. Complex formation by all five homologs of mammalian translation initiation factor 3 subunits from yeast Saccharomyces cerevisiae
4. Structure of cDNAs encoding human eukaryotic initiation factor 3 subunits. Possible roles in RNA binding and macromolecular assembly
5. Heterologous modules for efficient and versatile PCR-based gene targeting in Schizosaccharomyces pombe
6. PDGF2/c-sis mRNA leader contains a differentiation-linked internal ribosomal entry site (D-IRES)
7. A new group of conserved coactivators that increase the specificity of AP-1 transcription factors
8. Comparison of Schizosaccharomyces pombe expression systems
9. Functional characterization of the internal ribosome entry site of eIF4G mRNA
10. The PCI domain: A common theme in three multiprotein complexes
11. Two independent internal ribosome entry sites are involved in translation initiation of vascular endothelial growth factor mRNA
12. Sum1, a highly conserved WD-repeat protein, suppresses S-M checkpoint mutants and inhibits the osmotic stress cell cycle response in fission yeast
13. Translational controls impinging on the 5'-untranslated region and initiation factor proteins
14. A segment of the 5' nontranslated region of encephalomyocarditis virus RNA directs internal entry of ribosomes during in vitro translation
15. The Arabidopsis homologue of an eIF3 complex subunit associates with the COP9 complex
16. Cap-independent translation initiation in Xenopus oocytes
17. Internal initiation of translation mediated by the 5' leader of a cellular mRNA
18. Int-6, a highly conserved, widely expressed gene, is mutated by mouse mammary tumor virus in mammary preneoplasia
19. nmt1 of fission yeast: A highly transcribed gene completely repressed by thiamine
20. Thiamine-repressible expression vectors pREP and pRIP for fission yeast
21. Molecular genetic analysis of fission yeast Schizosaccharomyces pombe
22. The COP9/signalosome complex is conserved in fission yeast and has a role in S phase
23. Cloning cell cycle regulatory genes by transcomplementation in yeast
24. Internal initiation of translation of eukaryotic mRNA directed by a sequence derived from poliovirus RNA
25. Identification of a translation initiation factor 3 (eIF3) core complex, conserved in yeast and mammals, that interacts with eIF5
26. Mutations in translation initiation factors lead to increased rates of deadenylation and decapping of mRNAs in Saccharomyces cerevisiae
27. A novel protein complex involved in signal transduction possessing similarities to 26S proteasome subunits
28. + -dependent transcription and is implicated in the maintenance of chromosome structure
29. Specific interaction of eukaryotic translation initiation factor 3 with the 5' nontranslated regions of hepatitis C virus and classical swine fever virus RNAs
30. Resistance to diverse drugs and ultraviolet light conferred by overexpression of a novel human 26 S proteasome subunit
31. Translation of vascular endothelial growth factor mRNA by internal ribosome entry: Implications for translation under hypoxia
32. Fission yeast pap1-dependent transcription is negatively regulated by an essential nuclear protein, crm1
33. Fission yeast genes that confer resistance to staurosporine encode an AP-1-like transcription factor and a protein kinase related to the mammalian ERK1/MAP2 and budding yeast FUS3 and KSS1 kinases
34. Regulation of the fission yeast transcription factor Pap1 by oxidative stress: Requirement for the nuclear export factor Crm1 (Exportin) and the stress-activated MAP kinase
35. Translation of CUG-but not AUG-initiated forms of human fibroblast growth factor 2 is activated in transformed and stressed cells
36. Arabidopsis COP9 is a component of a novel signaling complex mediating light control of development
37. The COP9 complex is conserved between plants and mammals and is related to the 26S proteasome regulatory complex