Reduced bone formation in alcohol-induced osteopenia is associated with elevated p21 expression in bone marrow cells in aldehyde dehydrogenase 2-disrupted mice

Bone

Volumn 48, Issue 5, 2011, Pages 1075-1086

  Shimizu, Yuki ^a   Sakai, Akinori ^a   Menuki, Kunitaka ^a   Mori, Toshiharu ^a   Isse, Toyohi ^a   Oyama, Tsunehiro ^a   Kawamoto, Toshihiro ^a   Nakamura, Toshitaka ^a  

^a UNIVERSITY OF OCCUPATIONAL AND ENVIRONMENTAL HEALTH   (Japan)

Author keywords

Alcohol; Aldehyde dehydrogenase; Bone marrow; Histomorphometry; P21

Indexed keywords

ALCOHOL; ALDEHYDE DEHYDROGENASE ISOENZYME 2; MESSENGER RNA; PROTEIN PAK18; REGULATOR PROTEIN; UNCLASSIFIED DRUG;

ALCOHOL CONSUMPTION; ALDH2 GENE; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BONE MARROW CELL; BONE MINERALIZATION; BONE STRUCTURE; CELL DIFFERENTIATION; CONTROLLED STUDY; DEVELOPMENTAL DISORDER; FEMUR; GENE; GENE EXPRESSION; GROWTH RATE; KNOCKOUT MOUSE; MALE; MORPHOMETRICS; MOUSE; NONHUMAN; OSSIFICATION; OSTEOBLAST; OSTEOCALCIN GENE; OSTEOPENIA; OSTEOPONTIN GENE; OSTERIX GENE; P21 GENE; TIBIA; TRABECULAR BONE; TYPE I COLLAGEN GENE; WILD TYPE;

ACID PHOSPHATASE; ALCOHOLS; ALDEHYDE DEHYDROGENASE; ALKALINE PHOSPHATASE; ANIMALS; BIOLOGICAL MARKERS; BODY WEIGHT; BONE DENSITY; BONE DISEASES, METABOLIC; BONE MARROW CELLS; BONE REMODELING; CELL ADHESION; CELL CYCLE; COLONY-FORMING UNITS ASSAY; CYCLIN-DEPENDENT KINASE INHIBITOR P21; GENE EXPRESSION REGULATION; GIANT CELLS; ISOENZYMES; LIVER FUNCTION TESTS; MALE; MICE; ORGAN SIZE; OSTEOCALCIN; OSTEOCLASTS; OSTEOGENESIS; RNA, MESSENGER; TIBIA;

EID: 79954615199     PISSN: 87563282     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bone.2011.01.008     Document Type: Article

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