Alcohol-related diseases of the mouth and throat

Bailliere's Best Practice and Research in Clinical Gastroenterology

Volumn 17, Issue 4, 2003, Pages 543-555

  Riedel, Frank ^a   Goessler, Ulrich ^a   Hörmann, Karl ^a  

^a UNIVERSITY OF HEIDELBERG   (Germany)

Author keywords

Alcohol; Head and neck; Microbes; Mucosa; Salivary glands; Squamous cell carcinoma

Indexed keywords

ALCOHOL; CARCINOGEN; TOBACCO SMOKE; ACETALDEHYDE; ALCOHOL DEHYDROGENASE; CATALASE;

ALCOHOL CONSUMPTION; ALCOHOL METABOLISM; ALCOHOLIC BEVERAGE; CANCER RISK; CANCER SUSCEPTIBILITY; CARCINOGENESIS; CELL PROLIFERATION; CIGARETTE SMOKING; CORRELATION ANALYSIS; DISEASE ASSOCIATION; ENVIRONMENTAL EXPOSURE; EPIDEMIOLOGICAL DATA; GENOTOXICITY; HEAD AND NECK CANCER; HUMAN; INTESTINE FUNCTION; LEUKOPLAKIA; MORTALITY; MOUTH CARCINOMA; MOUTH DISEASE; MOUTH FLORA; MOUTH INFECTION; MUTAGENESIS; REVIEW; RISK ASSESSMENT; SALIVARY GLAND FUNCTION; SOCIAL BEHAVIOR; THROAT DISEASE; ALCOHOL ABUSE; BEER; CANDIDA ALBICANS; CARCINOMA; DNA REPAIR; DYSPLASIA; GENETIC ANALYSIS; INFECTION; MICROORGANISM; MOUTH MUCOSA; NONHUMAN; SALIVARY GLAND; SMOKING; STAPHYLOCOCCUS; WHISKEY; WINE;

ALCOHOL DRINKING; ALCOHOLIC BEVERAGES; ALCOHOLISM; ANIMALS; DNA REPAIR; DOSE-RESPONSE RELATIONSHIP, DRUG; DRUG SYNERGISM; ETHANOL; HEAD AND NECK NEOPLASMS; HUMANS; MOUTH MUCOSA; MUTAGENS; RISK; SALIVA; SALIVARY GLANDS;

EID: 0347983824     PISSN: 15216918     EISSN: None     Source Type: Journal    
DOI: 10.1016/S1521-6918(03)00019-2     Document Type: Review

References (100)

1. Blot W.J. McLaughlin J.K. Winn D.M. et al. Smoking and drinking in relation to oral and pharyngeal cancer Cancer Research 48 1988 3282-3287
2. Maier H. Dietz A. Gewelke U. et al. Tobacco and alcohol and the risk of head and neck cancer Clinical Investigation 70 1992 320-327
3. Mashberg A. Boffetta P. Winkelman R. et al. Tobacco smoking, alcohol drinking, and cancer of the oral cavity and oropharynx among U.S. veterans Cancer 72 1993 1369-1375
4. Rothman K. Keller A. The effect of joint exposure to alcohol and tobacco on risk of cancer of the mouth and pharynx Journal of Chronic Disease 25 1972 711-716
5. Tuyns A.J. Esteve J. Raymond L. et al. Cancer of the larynx/hypopharynx, tobacco and alcohol: IARC international case-control study in Turin and Varese (Italy), Zaragoza and Navarra (Spain), Geneva (Switzerland) and Calvados (France) International Journal of Cancer 41 1988 483-491
6. Hörmann K, Riedel F & Hirth K. Alkohol und Mundhöhle/Pharynx. In Singer MV & Teyssen S (eds) Alkohol und Alkoholfolgeerkrankungen-Grundlagen-Diagnostik-Therapie. Kapitel 12. Springer: Heidelberg, 1998.
7. Kato I. Nomura A.M. Alcohol in the aetiology of upper aerodigestive tract cancer European Journal of Cancer. B Oral Oncology 30B 1994 75-81
8. Ogden G.R. Wight A.J. Aetiology of oral cancer: alcohol British Journal of Oral and Maxillofacial Surgery 36 1998 247-251
9. Seitz H.K. Matsuzaki S. Yokoyama A. et al. Alcohol and cancer Alcoholism, Clinical and Experimental Research 25 2001 137S-143S
10. Tuyns A. Epidemiology of alcohol and cancer Cancer Research 39 1979 2840-2843
11. Wight A.J. Ogden G.R. Possible mechanisms by which alcohol may influence the development of oral cancer-a review Oral Oncology 34 1998 441-447
12. Johnson N.W. Warnakulasuriya K.A. Epidemiology and aetiology of oral cancer in the United Kingdom Community Dental Health 10 1993 13-29
13. Obe G. Anderson D. International Commission for Protection against Environmental Mutagens and Carcinogens (ICPEMC) Working Paper No. 15/1. Genetic effects of ethanol Mutation Research 186 1987 177-200
14. Obe G. Ristow H. Mutagenic, cancerogenic and teratogenic effects of alcohol Mutation Research 65 1979 229-259
15. Korte A. Wagner H.M. Obe G. Simultaneous exposure of Chinese hamsters to ethanol and cigarette smoke: cytogenetic aspects Toxicology 20 1981 237-246
16. Obe G. Jonas R. Schmidt S. Metabolism of ethanol in vitro produces a compound which induces sister-chromatid exchanges in human peripheral lymphocytes in vitro: acetaldehyde not ethanol is mutagenic Mutation Research 174 1986 47-51
17. Hsu T.C. Furlong C. The role of ethanol in oncogenesis of the upper aerodigestive tract; inhibition of DNA repair Anticancer Research 11 1991 1995-1998
18. Lieber C.S. Seitz H.K. Garro A.J. et al. Alcohol-related diseases and carcinogenesis Cancer Research 39 1979 2863-2886
19. Wynder E.L. Mushinski M.H. Spivak J.C. Tobacco and alcohol consumption in relation to the development of multiple primary cancers Cancer 40 1977 1872-1878
20. Feldman J.G. Hazan M. A case-control investigation of alcohol, tobacco, and diet in head and neck cancer Preventional Medicine 4 1975 444-463
21. Bross I.D. Coombs J. Early onset of oral cancer among women who drink and smoke Oncology 33 1976 136-139
22. Wynder E.L. Lemon F.R. Bross I.J. Cancer and coronary artery disease among Seventh Day Adventists Cancer 12 1959 1016-1028
23. Talamini R. Franceschi S. Barra S. et al. The role of alcohol in oral and pharyngeal cancer in non-smokers, and of tobacco in non-drinkers International Journal of Cancer 46 1990 391-393
24. McCoy G.D. Hecht S.S. Katayama S. et al. Differential effect of chronic ethanol consumption on the carcinogenicity of N-nitrosopyrrolidine and N′-nitrosonornicotine in male Syrian golden hamsters Cancer Research 41 1981 2849-2854
25. Brugere J. Guenel P. Leclerc A. et al. Differential effects of tobacco and alcohol in cancer of the larynx, pharynx and mouth Cancer 57 1986 391-395
26. Blot W.J. Devesa S.S. McLaughlin J.K. et al. Oral and pharyngeal cancers Cancer Survey 19-20 1994 23-42
27. Boyle P. Zheng T. Macfarlane G.J. et al. Recent advances in the etiology and epidemiology of head and neck cancer Current Opinion in Oncology 2 1990 539-545
28. Herity B. Moriarty M. Bourke G.J. et al. A case-control study of head and neck cancer in the Republic of Ireland British Journal of Cancer 43 1981 177-182
29. Llewelyn J. Mitchell R. Smoking, alcohol and oral cancer in south east Scotland: a 10-year experience British Journal of Oral and Maxillofacial Surgery. 32 1994 146-152
30. Jovanovic A. Schulten E.A. Kostense P.J. et al. Tobacco and alcohol related to the anatomical site of oral squamous cell carcinoma Journal of Oral Pathology and Medicine 22 1993 459-462
31. Maier H. Tisch M. Alkoholkonsum und Krebsrisiko im Bereich des oberen Verdauungstrakts HNO 47 1999 764-765
32. Gronbaek M. Becker U. Johansen D. et al. Population based cohort study of the association between alcohol intake and cancer of the upper digestive tract British Medical Journal 317 1998 844-847
33. Maier H. Gewelke U. Dietz A. et al. Risk factors of cancer of the larynx: results of the Heidelberg case-control study Otolaryngology - Head and Neck Surgery 107 1992 577-582
34. Lyon J.L. Gardner J.W. Klauber M. et al. Low cancer incidence and mortality in Utah Cancer 39 1977 2608-2618
35. Lyon J.L. Gardner J.W. West D.W. Cancer incidence in Mormons and non-Mormons in Utah during 1967-75 Journal of the National Cancer Institute 65 1980 1055-1061
36. Enstrom J.E. Cancer mortality among Mormons in California during 1968-75 Journal of the National Cancer Institute 65 1980 1073-1082
37. Adami H.O. McLaughlin J.K. Hsing A.W. et al. Alcoholism and cancer risk: a population-based cohort study Cancer Causes and Control 3 1992 419-425
38. Kissin B. Kaley M.M. Su W.H. et al. Head and neck cancer in alcoholics. The relationship to drinking, smoking, and dietary patterns Journal of the American Medical Association 224 1973 1174-1175
39. Bundgaard T. Wildt J. Frydenberg M. et al. Case-control study of squamous cell cancer of the oral cavity in Denmark Cancer Causes and Control 6 1995 57-67
40. Carstensen J.M. Bygren L.O. Hatschek T. Cancer incidence among Swedish brewery workers International Journal of Cancer 45 1990 393-396
41. Jensen O.M. Dietary factors in colon carcinogenesis with special emphasis on the role of dietary fat and dietary fibre Progression of Clinical Biological Research 132D 1983 151-158
42. Kabat G.C. Wynder E.L. Type of alcoholic beverage and oral cancer International Journal of Cancer 43 1989 190-194
43. Wynder E.L. Bross I.J. Feldman R. A study on the etiology factors in cancer of the mouth Cancer 16 1957 1300-1323
44. Leclerc A. Brugere J. Luce D. et al. Type of alcoholic beverage and cancer of the upper respiratory and digestive tract European Journal of Cancer and Clinical Oncology 23 1987 529-534
45. Marshall A.M. Wright A.L. Action on alcohol British Medical Journal 24 1979 546
46. Kleinjans J.C. Moonen E.J. Dallinga J.W. et al. Polycyclic aromatic hydrocarbons in whiskies Lancet 348 1996 1731
47. Homann N. Tillonen J. Meurman J.H. et al. Increased salivary acetaldehyde levels in heavy drinkers and smokers: a microbiological approach to oral cavity cancer Carcinogenesis 21 2000 663-668
48. Bird R.P. Draper H.H. Basrur P.K. Effects of malonaldehyde and acetaldehyde on cultured mammalian cells. Production of micronuclei and chromosomal aberrations Mutation Research 101 1982 237-246
49. Dellarco V.L. A mutagenicity assessment of acetaldehyde Mutation Research 195 1988 1-20
50. Helander A. Lindahl-Kiessling K. Increased frequency of acetaldehyde-induced sister-chromatid exchanges in human lymphocytes treated with an aldehyde dehydrogenase inhibitor Mutation Research 264 1991 103-107
51. Homann N. Kärkkäinen P. Koivisto T. et al. Effect of acetaldehyde on cell regeneration and differentiation of the upper gastrointestinal tract mucosa Journal of the National Cancer Institute 89 1997 1692-1697
52. Harty I.C. Caporaso N.E. Hayes R.B. et al. Alcohol dehydrogenase 3 genotype and risk of oral cavity and pharyngeal cancers Journal of the National Cancer Institute 89 1997 1698-1705
53. Yokoyama A. Muramatsu T. Ohmori T. et al. Esophageal cancer and aldehyde dehydrogenase-2 genotypes in Japanese males Cancer Epidemiology, Biomarkers and Prevention 5 1996 99-102
54. Yokoyama A. Muramatsu T. Ohmori T. et al. Alcohol-related cancers and aldehyde dehydrogenase-2 in Japanese alcoholics Carcinogenesis 19 1998 1383-1387
55. Yokoyama A. Muramutsu T. Ohmori T. et al. Multiple primary esophageal and concurrent upper aerodigestive tract cancer and the aldehyde dehydrogenase type-2 genotype of Japanese alcoholics Cancer 77 1996 1986-1990
56. Yokoyama A. Ohmori T. Muramatsu T. et al. Cancer screening of upper aerodigestive tract in Japanese alcoholics with reference to drinking and smoking habits and aldehyde dehydrogenase-2 International Journal of Cancer 68 1996 313-316
57. Goedde H.W. Singh S. Agarwal D.P. et al. Genotyping of mitochondrial aldehyde dehydrogenase in blood samples using allele-specific oligonucleotides: comparison with phenotyping in hair roots Human Genetics 81 1989 305-307
58. Moreno A. Pares A. Ortiz J. et al. Alcohol dehydrogenase from human stomach: variability in normal mucosa and effect of age, gender, ADH3 phenotype and gastric region Alcohol 29 1994 663-671
59. Dong Y.J. Peng T.K. Yin S.J. Expression and activities of class IV alcohol dehydrogenase and class III aldehyde dehydrogenase in human mouth Alcohol 13 1996 257-262
60. Mascres C. Ming-Wen F. Joly J.G. Morphologic changes of the esophageal mucosa in the rat after chronic alcohol ingestion Experimental Pathology 25 1984 147-153
61. Müller P. Hepke B. Meldau U. et al. Tissue damage in the rabbit oral mucosa by acute and chronic direct toxic action of different alcohol concentrations Experimental Pathology 24 1983 171-181
62. Maier H. Weidauer H. Zöller J. et al. The effect of chronic ethanol consumption on the morphology of the oral mucosa Alcoholism, Clinical and Experimental Research 18 1994 387-391
63. Valentine J.A. Scott J. West C.R. et al. A histological analysis of the early effects of alcohol and tobacco usage on human lingual epithelium Journal of Oral Pathology 14 1985 654-665
64. Simanowski U.A. Stickel F. Maier H. et al. Effect of alcohol on gastrointestinal cell regeneration as a possible mechanism in alcohol-associated carcinogenesis Alcohol 12 1995 111-115
65. Squier C.A. Cox P. Hall B.K. Enhanced penetration of nitrosonornicotine across oral mucosa in the presence of ethanol Journal of Oral Pathology 15 1986 276-279
66. Howie N.M. Trigkas T.K. Cruchley A.T. et al. Short-term exposure to alcohol increases the permeability of human oral mucosa Oral Disease 7 2001 349-354
67. Bardell D. Smith E.J. An in vitro study of mixed populations of normal oropharyngeal bacteria after exposure to cigarette smoke in vitro Microbios 32 1971 7-13
68. Bastiaan R.J. Waite I.M. Effect of tobacco smoke on plaque development and gingivitis Journal of Periodontology 49 1978 480-482
69. Colman G. Beighton D. Chalk A.J. et al. Cigarette smoking and the microbial flora of the mouth Australian Dentistry Journal 21 1976 111-118
70. McGregor I.D.M. Smoking, saliva and salivation Journal of Dentistry 18 1988 14-17
71. Maier H. Zöller J. Herrmann A. et al. Dental status and oral hygiene in patients with head and neck cancer Otolaryngology-Head and Neck Surgery 108 1993 655-661
72. La Vecchia C. Tavani A. Franceschi S. et al. Epidemiology and prevention of oral cancer European Journal of Cancer and Oral Oncology 33 1997 302-312
73. Mashberg A. Garfinkel L. Harris S. Alcohol as a primary risk factor in oral squamous carcinoma Canadian Cancer Journal for Clinicians 31 1981 146-155
74. Jokelainen K. Heikkonen E. Roine R. et al. Increased acetaldehyde production by mouthwashings from patients with oral cavity, laryngeal or pharyngeal cancer Alcoholism, Clinical and Experimental Research 20 1996 1206-1210
75. Jokelainen K. Siitonen A. Jousimies-Somer H. et al. In vitro alcohol dehydrogenase-mediated acetaldehyde production by aerobic bacteria representing the normal colonic flora in man Alcoholism, Clinical and Experimental Research 20 1996 967-972
76. Miyakawa H, Baraona E, Chang JC et al. Oxidation of ethanol to acetaldehyde by bronchopulmonary washings: role of bacteria. Alcoholism, Clinical and Experimental Research 1986; 10: 517-520.
77. Pikkarainen P.H. Baraona E. Jauhonen P. et al. Contribution of oropharynx flora and of lung microsomes to acetaldehyde in expired air after alcohol ingestion Journal of Laboratory and Clinical Medicine 97 1981 631-636
78. Mandel L. Baurmash H. Parotid enlargement due to alcoholism Journal of the American Dentistry Association 82 1971 369-373
79. Abelson D.C. Mandel I.D. Karmiol M. Salivary studies in alcoholic cirrhosis Oral Surgery, Oral Medicine and Oral Pathology 41 1976 188-192
80. Maier H. Born I.A. Veith S. et al. The effect of ethanol consumption on salivary gland morphology and function in the rat Alcoholism, Clinical and Experimental Research 10 1988 425-429
81. Graham S. Dayal H. Rohrer T. et al. Dentition, diet, tobacco, and alcohol in the epidemiology of oral cancer Journal of the National Cancer Institute 59 1977 1611-1618
82. Nishioka H. Nishi K. Kyokane K. Human saliva inactivates mutagenicity of carcinogens Mutation Research 85 1981 323-333
83. Stich H.F. Rosin M.P. Bryson L. The inhibitory effect of whole and deproteinized saliva on mutagenicity and clastogenicity resulting from a model nitrosation reaction Mutation Research 97 1982 283-292
84. Homann N. Jousimies-Somer H. Jokelainen K. et al. High acetaldehyde levels in saliva after ethanol consumption: methodological aspects and pathogenetic implications Carcinogenesis 18 1997 1739-1743
85. Hsu T.C. Furlong C. Spitz M.R. Ethyl alcohol as a cocarcinogen with special reference to the aerodigestive tract: a cytogenetic study Anticancer Research 11 1991 1097-1101
86. Mufti S.I. Alcohol acts to promote incidence of tumours Cancer Detection and Prevention 16 1992 157-162
87. 6-methylguanine transferase-mediated repair of alkylated DNA Alcoholism, Clinical and Experimental Research 10 1986 73S-77S
88. Mufti S.I. Salvagnini M. Lieber C.S. et al. Chronic ethanol consumption inhibits repair of dimethylnitrosamine-induced DNA alkylation Biochemical and Biophysical Research Communications 152 1988 423-431
89. Elzay R.P. Local effect of alcohol in combination with DMBA on hamster cheek pouch Journal of Dentistry and Research 45 1966 1788-1795
90. Lin Y.C. Ho I.C. Lee T.C. Ethanol and acetaldehyde potentiate the clastogenicity of ultraviolet light, methyl methanesulfonate, mitomycin C and bleomycin in Chinese hamster ovary cells Mutation Research 216 1989 93-99
91. Hsu T.C. Alcohol: a cocarcinogen in head and neck malignancies Advances in Experimental Medicine and Biology 320 1992 35-37
92. Patel R.K. Trivedi A.H. Jaju R.J. et al. Ethanol potentiates the clastogenicity of pan masala-an in vitro experience Carcinogenesis 15 1994 2017-2021
93. Deleyiannis F.W. Thomas D.B. Vaughan T.L. et al. Alcoholism: independent predictor of survival in patients with head and neck cancer Journal of the National Cancer Institute 88 1996 542-549
94. Lieber C.S. Baraona E. Leo M.A. et al. International Commission for Protection against Environmental Mutagens and Carcinogens (ICPEMC) Working Paper No. 15/2. Metabolism and metabolic effects of ethanol, including interaction with drugs, carcinogens and nutrition Mutation Research 186 1987 201-233
95. Garro A.J. Seitz H.K. Lieber C.S. Enhancement of dimethylnitrosamine metabolism and activation to a mutagen following chronic ethanol consumption Cancer Research 41 1981 120-124
96. Tates A.D. de Vogel N. Neuteboom I. Cytogenetic effects in hepatocytes, bone-marrow cells and blood lymphocytes of rats exposed to ethanol in the drinking water Mutation Research 79 1980 285-288
97. Harris C.K. Warnakulasuriya K.A. Johnson N.W. et al. Oral health in alcohol misusers Community Dental Health 13 1996 199-203
98. Valin N. Haybron D. Groves L. Mower H.F. The nitrosation of alcohol-induced metabolites produces mutagenic substances Mutation Research 158 1985 159-168
99. 6-methyldeoxyguanosine from concurrently administered N-nitrosomethylbenzylamine in rats: a dose-response study Carcinogenesis 13 1992 1171-1175
100. Swann P.F. Coe A.M. Mace R. Ethanol and dimethylnitrosamine and diethylnitrosamine metabolism and disposition in the rat. Possible relevance to the influence of ethanol on human cancer incidence Carcinogenesis 5 1984 1337-1343