Genetic disruption of all NO synthase isoforms enhances BMD and bone turnover in mice in vivo: Involvement of the renin-angiotensin system

Journal of Bone and Mineral Research

Volumn 23, Issue 5, 2008, Pages 633-643

  Sabanai, Ken ^a   Tsutsui, Masato ^a   Sakai, Akinori ^a   Hirasawa, Hideyuki ^a   Tanaka, Shinya ^a   Nakamura, Eiichiro ^a   Tanimoto, Akihide ^a   Sasaguri, Yasuyuki ^a   Ito, Masako ^b   Shimokawa, Hiroaki ^c   Nakamura, Toshitaka ^a   Yanagihara, Nobuyuki ^a  

^a UNIVERSITY OF OCCUPATIONAL AND ENVIRONMENTAL HEALTH   (Japan)

^b NAGASAKI UNIVERSITY GRADUATE SCHOOL OF BIOMEDICAL SCIENCES   (Japan)

^c TOHOKU UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

Author keywords

Angiotensin II; Bone formation; Bone metabolism; Bone resorption; NO synthase

Indexed keywords

ALKALINE PHOSPHATASE; ANGIOTENSIN 1 RECEPTOR; ANGIOTENSIN 1 RECEPTOR ANTAGONIST; BETA ACTIN; BIOCHEMICAL MARKER; BONE MORPHOGENETIC PROTEIN 2; DEOXYPYRIDINOLINE; ENDOTHELIAL NITRIC OXIDE SYNTHASE; INDUCIBLE NITRIC OXIDE SYNTHASE; ISOENZYME; NEURONAL NITRIC OXIDE SYNTHASE; NITRIC OXIDE; NITRIC OXIDE SYNTHASE; OSTEOCALCIN; OSTEOCLAST DIFFERENTIATION FACTOR; PROTEIN C FOS; TRANSCRIPTION FACTOR OSTERIX; TRANSCRIPTION FACTOR RUNX2;

ALKALINE PHOSPHATASE BLOOD LEVEL; ANIMAL CELL; ANIMAL TISSUE; ARTICLE; BONE DENSITY; BONE METABOLISM; BONE MINERAL; BONE REMODELING; BONE TURNOVER; CELL COUNT; CELL STRUCTURE; CELL SURFACE; DUAL ENERGY X RAY ABSORPTIOMETRY; GENE DISRUPTION; HOMEOSTASIS; IN VIVO STUDY; MALE; MOUSE; NONHUMAN; OSSIFICATION; OSTEOBLAST; OSTEOCLAST; OSTEOLYSIS; RENIN ANGIOTENSIN ALDOSTERONE SYSTEM; WILD TYPE;

ANIMALS; BONE DENSITY; BONE REMODELING; ISOENZYMES; MALE; MICE; MICE, INBRED C57BL; NITRIC OXIDE SYNTHASE; RENIN-ANGIOTENSIN SYSTEM;

EID: 42449108630     PISSN: 08840431     EISSN: None     Source Type: Journal    
DOI: 10.1359/jbmr.080107     Document Type: Article

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