Loss of desmocollin-2 confers a tumorigenic phenotype to colonic epithelial cells through activation of Akt/β-catenin signaling

Molecular Biology of the Cell

Volumn 22, Issue 8, 2011, Pages 1121-1134

  Kolegraff, Keli ^a   Nava, Porfirio ^a   Helms, My N ^b   Parkos, Charles A ^a   Nusrat, Asma ^a  

^a Department of Pathology and Laboratory Medicine ^*  (United States)

^b EMORY UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BETA CATENIN; DESMOCOLLIN; DESMOCOLLIN 2; DESMOSOMAL CADHERIN; PROTEIN KINASE B; UNCLASSIFIED DRUG;

ARTICLE; CARCINOMA CELL; CELL PROLIFERATION; COLON ADENOCARCINOMA; COLON CARCINOGENESIS; COLON MUCOSA; CONTROLLED STUDY; DOWN REGULATION; ENZYME ACTIVATION; ENZYME INHIBITION; EPITHELIUM CELL; HUMAN; HUMAN CELL; HUMAN TISSUE; IN VIVO STUDY; PHENOTYPE; PRIORITY JOURNAL; PROTEIN DEPLETION; PROTEIN FUNCTION; SIGNAL TRANSDUCTION; TRANSCRIPTION REGULATION; TUMOR GROWTH;

ANIMALS; BETA CATENIN; CACO-2 CELLS; CELL PROLIFERATION; COLON; COLONIC NEOPLASMS; COLORECTAL NEOPLASMS; DESMOCOLLINS; DESMOGLEIN 2; DESMOSOMES; GENE EXPRESSION REGULATION, NEOPLASTIC; GENE SILENCING; HUMANS; MICE; MICE, KNOCKOUT; ONCOGENE PROTEIN V-AKT; PHENOTYPE; PROTEIN KINASE INHIBITORS; RNA, SMALL INTERFERING; SIGNAL TRANSDUCTION; TRANSCRIPTION, GENETIC; TRANSFECTION;

EID: 79954610504     PISSN: 10591524     EISSN: 19394586     Source Type: Journal    
DOI: 10.1091/mbc.E10-10-0845     Document Type: Article

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