Reversal of catabolism by beta-blockade after severe burns

New England Journal of Medicine

Volumn 345, Issue 17, 2001, Pages 1223-1229

  Herndon, David N ^a,b   Hart, David W ^a   Wolf, Steven E ^a   Chinkes, David L ^a   Wolfe, Robert R ^a  

^a SHRINERS HOSPITALS FOR CHILDREN   (United States)

^b SHRINERS HOSPITALS FOR CHILDREN   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BETA ADRENERGIC RECEPTOR BLOCKING AGENT; MUSCLE PROTEIN; POTASSIUM; PROPRANOLOL;

ARTICLE; BETA ADRENERGIC RECEPTOR BLOCKING; BODY COMPOSITION; BODY SURFACE; BURN; CHILD HOSPITALIZATION; CLINICAL ARTICLE; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; DISEASE SEVERITY; ENERGY EXPENDITURE; FEMALE; HEART RATE; HUMAN; HYPERMETABOLISM; MALE; MEASUREMENT; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN METABOLISM; RANDOMIZED CONTROLLED TRIAL; SCHOOL CHILD; SIDE EFFECT;

ADRENERGIC BETA-ANTAGONISTS; BODY COMPOSITION; BURNS; CHILD; ENERGY METABOLISM; FEMALE; HEART RATE; HUMANS; MALE; MUSCLE PROTEINS; MUSCLE, SKELETAL; PROPRANOLOL;

EID: 0035950685     PISSN: 00284793     EISSN: None     Source Type: Journal    
DOI: 10.1056/NEJMoa010342     Document Type: Article

References (34)

1. Sequential changes in the metabolic response in critically injured patients during the first 25 days after blunt trauma
2. Posttraumatic skeletal muscle proteolysis: The role of the hormonal environment
3. Persistence of muscle catabolism after severe burn
4. Anticatabolic and anabolic strategies in critical illness: A review of current treatment modalities
5. Relationship of increased oxygen consumption to catecholamine excretion in thermal burns
6. Catecholamines: Mediator of the hypermetabolic response to thermal injury
7. Urinary output of adrenaline and noradrenaline in severe thermal burns
8. Metabolic changes in burned patients
9. Systemic and pulmonary hemodynamic changes accompanying thermal injury
10. The metabolic response to burns
11. Weight loss following thermal injury
12. Effect of propranolol administration on hemodynamic and metabolic responses of burned pediatric patients
13. Improved myocardial oxygen utilization following propranolol infusion in adolescents with postburn hypermetabolism
14. Prolonged use of propranolol safely decreases cardiac work in burned children
15. Effects of beta-blockade on energy metabolism following burns
16. Effect of atenolol on mortality and cardiovascular morbidity after noncardiac surgery
17. Determinants of skeletal muscle catabolism after severe burn
18. Vars Research Award: A new model to determine in vivo the relationship between amino acid transmembrane transport and protein kinetics in muscle
19. Increased rates of muscle protein turnover and amino acid transport after resistance exercise in humans
20. Total body potassium in the infant
21. Total sodium, potassium, and chloride in adult man
22. Four-component model of body composition in children: Density and hydration of fat-free mass and comparison with simpler models
23. Effect of exogenous growth hormone on whole-body and isolated-limb protein kinetics in burned patients
24. Lipolysis in burned patients is stimulated by the beta 2-receptor for catecholamines
25. Effects of dietary clenbuterol on metabolism of the hindquarters in steers
26. The action of the beta-agonist clenbuterol on protein and energy metabolism in fattening wether lambs
27. Stimulation of muscle protein synthesis by long-term insulin infusion in severely burned patients
28. Muscle protein catabolism after severe burn: Effects of IGF-1/IGFBP-3 treatment
29. Anabolic effects of oxandrolone after severe burn
30. Propranolol diminishes extremity blood flow in burned patients
31. Increased rates of whole body protein synthesis and breakdown in children recovering from burns
32. Timing of amino acid-carbohydrate ingestion alters anabolic response of muscle to resistance exercise
33. Skeletal muscle mass: Evaluation of neutron activation and dual-energy X-ray absorptiometry methods
34. Cold stress response in patients with severe burns after beta-blockade