Atrogin-1, MuRF1, and FoXo, as well as phosphorylated GSK-3β and 4E-BP1 are reduced in skeletal muscle of chronic spinal cord-injured patients

Muscle and Nerve

Volumn 40, Issue 1, 2009, Pages 69-78

  Léger, Bertrand ^a,b   Senese, Rosalba ^c   Al Khodairy, Abdul W ^b   Dériaz, Olivier ^a,b   Gobelet, Charles ^a,b   Giacobino, Jean Paul ^a   Russell, Aaron P ^b,d  

^a Institut de Recherche en Réadaptation IRR   (Switzerland)

^b SUVA   (Switzerland)

^c SECOND UNIVERSITY OF NAPLES   (Italy)

^d DEAKIN UNIVERSITY   (Australia)

Author keywords

Akt; Atrogin 1; Muscle atrophy; Protein degradation; Protein synthesis; Spinal cord injury

Indexed keywords

ATROGIN 1; GLYCOGEN SYNTHASE KINASE 3BETA; INITIATION FACTOR 4E BINDING PROTEIN 1; MAMMALIAN TARGET OF RAPAMYCIN; MESSENGER RNA; MUSCLE RING FINGER 1 PROTEIN; MYOSTATIN; PROTEIN KINASE B; S6 KINASE; SOMATOMEDIN; TRANSCRIPTION FACTOR FOXO;

ADULT; ARTICLE; CHRONIC DISEASE; CLINICAL ARTICLE; CONTROLLED STUDY; DOWN REGULATION; FEMALE; HUMAN; HUMAN TISSUE; MALE; PRIORITY JOURNAL; PROTEIN DETERMINATION; SKELETAL MUSCLE; SPINAL CORD INJURY;

ADAPTOR PROTEINS, SIGNAL TRANSDUCING; ADULT; CASE-CONTROL STUDIES; CHRONIC DISEASE; DOWN-REGULATION; FORKHEAD TRANSCRIPTION FACTORS; GLYCOGEN SYNTHASE KINASE 3; HUMANS; MIDDLE AGED; MUSCLE PROTEINS; MUSCLE, SKELETAL; MYOSIN HEAVY CHAINS; MYOSTATIN; PHOSPHOPROTEINS; RNA, MESSENGER; SIGNAL TRANSDUCTION; SKP CULLIN F-BOX PROTEIN LIGASES; SPINAL CORD INJURIES; TIME FACTORS; TOMOGRAPHY, X-RAY COMPUTED; UBIQUITIN-PROTEIN LIGASES;

EID: 67650258512     PISSN: 0148639X     EISSN: 10974598     Source Type: Journal    
DOI: 10.1002/mus.21293     Document Type: Article

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