BH3-only activator proteins Bid and Bim are dispensable for Bak/Bax-dependent thrombocyte apoptosis induced by Bcl-xL deficiency molecular requisites for the mitochondrial pathway to apoptosis in platelets

Journal of Biological Chemistry

Volumn 286, Issue 16, 2011, Pages 13905-13913

  Kodama, Takahiro ^a   Takehara, Tetsuo ^a   Hikita, Hayato ^a   Shimizu, Satoshi ^a   Shigekawa, Minoru ^a   Li, Wei ^a   Miyagi, Takuya ^a   Hosui, Atsushi ^a   Tatsumi, Tomohide ^a   Ishida, Hisashi ^a   Kanto, Tatsuya ^a   Hiramatsu, Naoki ^a   Yin, Xiao Ming ^b   Hayashi, Norio ^c  

^a OSAKA UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

^b INDIANA UNIVERSITY   (United States)

^c KANSAI ROSAI HOSPITAL   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

ACTIVATOR PROTEINS; AMINO TERMINUS; ANTIAPOPTOTIC; APOPTOSIS; BAX ACTIVATION; BCL-2 FAMILY PROTEINS; CONFORMATIONAL CHANGE; CYTOSOLS; IN-VITRO; KNOCK OUTS; LIFE SPAN; MITOCHONDRIAL APOPTOSIS; MITOCHONDRIAL PATHWAYS; MOLECULAR MECHANISM; MULTI DOMAINS; SHARP CONTRAST; THROMBOCYTOPENIA;

CHEMICAL ACTIVATION; MITOCHONDRIA; OLIGOMERIZATION; OLIGOMERS; PLATELETS; PROTEINS;

CELL DEATH;

4 [4 (4' CHLORO 2 BIPHENYLYLMETHYL) 1 PIPERAZINYL] N [4 [3 DIMETHYLAMINO 1 (PHENYLTHIOMETHYL)PROPYLAMINO] 3 NITROBENZENESULFONYL]BENZAMIDE; BH3 PROTEIN; BIM PROTEIN; PROTEIN BAK; PROTEIN BAX; PROTEIN BCL XL; PROTEIN BID;

AMINO TERMINAL SEQUENCE; ANIMAL CELL; ANIMAL EXPERIMENT; APOPTOSIS; ARTICLE; CONFORMATIONAL TRANSITION; CONTROLLED STUDY; CYTOSOL; DISEASE SEVERITY; HUMAN; HUMAN CELL; IN VITRO STUDY; KNOCKOUT MOUSE; MITOCHONDRION; MOUSE; NONHUMAN; OLIGOMERIZATION; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN TRANSPORT; THROMBOCYTE; THROMBOCYTE LIFESPAN; THROMBOCYTOPENIA;

ANIMALS; APOPTOSIS; BCL-2 HOMOLOGOUS ANTAGONIST-KILLER PROTEIN; BCL-2-ASSOCIATED X PROTEIN; BCL-X PROTEIN; BH3 INTERACTING DOMAIN DEATH AGONIST PROTEIN; BIPHENYL COMPOUNDS; BLOOD PLATELETS; CYTOSOL; HUMANS; MICE; MICE, KNOCKOUT; MITOCHONDRIA; NITROPHENOLS; PIPERAZINES; PROTEIN TRANSPORT; SULFONAMIDES; THROMBOCYTOPENIA;

MUS;

EID: 79954606839     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M110.195370     Document Type: Article

References (46)

1. Holmsen, H. (1989) Ann. Med. 21, 23-30
2. Ault, K. A., and Knowles, C. (1995) Exp. Hematol. 23, 996-1001
3. Bertino, A. M., Qi, X. Q., Li, J., Xia, Y., and Kuter, D. J. (2003) Transfusion 43, 857-866
4. Li, J., Xia, Y., Bertino, A. M., Coburn, J. P., and Kuter, D. J. (2000) Transfusion 40, 1320-1329
5. Perrotta, P. L., Perrotta, C. L., and Snyder, E. L. (2003) Transfusion 43, 526-535
6. Vanags, D. M., Orrenius, S., and Aguilar-Santelises, M. (1997) Br. J. Haematol. 99, 824-831
7. Zhang, H., Nimmer, P. M., Tahir, S. K., Chen, J., Fryer, R. M., Hahn, K. R., Iciek, L. A., Morgan, S. J., Nasarre, M. C., Nelson, R., Preusser, L. C., Reinhart, G. A., Smith, M. L., Rosenberg, S. H., Elmore, S. W., and Tse, C. (2007) Cell Death Differ. 14, 943-951
8. Mason, K. D., Carpinelli, M. R., Fletcher, J. I., Collinge, J. E., Hilton, A. A., Ellis, S., Kelly, P. N., Ekert, P. G., Metcalf, D., Roberts, A. W., Huang, D. C., and Kile, B. T. (2007) Cell 128, 1173-1186
9. Kodama, T., Takehara, T., Hikita, H., Shimizu, S., Li, W., Miyagi, T., Hosui, A., Tatsumi, T., Ishida, H., Tadokoro, S., Ido, A., Tsubouchi, H., and Hayashi, N. (2010) Gastroenterology 138, 2487-2498
10. Chipuk, J. E., and Green, D. R. (2008) Trends Cell Biol. 18, 157-164
11. Adams, J. M., and Cory, S. (2007) Curr. Opin. Immunol. 19, 488-496
12. Leber, B., Lin, J., and Andrews, D. W. (2010) Oncogene 29, 5221-5230
13. Kim, H., Rafiuddin-Shah, M., Tu, H. C., Jeffers, J. R., Zambetti, G. P., Hsieh, J. J., and Cheng, E. H. (2006) Nat. Cell Biol. 8, 1348-1358
14. Willis, S. N., and Adams, J. M. (2005) Curr. Opin. Cell Biol. 17, 617-625
15. Willis, S. N., Fletcher, J. I., Kaufmann, T., van Delft, M. F., Chen, L., Czabotar, P. E., Ierino, H., Lee, E. F., Fairlie, W. D., Bouillet, P., Strasser, A., Kluck, R. M., Adams, J. M., and Huang, D. C. (2007) Science 315, 856-859
16. Kuwana, T., Bouchier-Hayes, L., Chipuk, J. E., Bonzon, C., Sullivan, B. A., Green, D. R., and Newmeyer, D. D. (2005) Mol. Cell 17, 525-535
17. Letai, A., Bassik, M. C., Walensky, L. D., Sorcinelli, M. D., Weiler, S., and Korsmeyer, S. J. (2002) Cancer Cell 2, 183-192
18. Billen, L. P., Kokoski, C. L., Lovell, J. F., Leber, B., and Andrews, D. W. (2008) PLoS Biol. 6, e147
19. Bouillet, P., Cory, S., Zhang, L. C., Strasser, A., and Adams, J. M. (2001) Dev. Cell 1, 645-653
20. Hikita, H., Takehara, T., Kodama, T., Shimizu, S., Hosui, A., Miyagi, T., Tatsumi, T., Ishida, H., Ohkawa, K., Li, W., Kanto, T., Hiramatsu, N., Hennighausen, L., Yin, X. M., and Hayashi, N. (2009) Hepatology 50, 1972-1980
21. Hikita, H., Takehara, T., Shimizu, S., Kodama, T., Li, W., Miyagi, T., Hosui, A., Ishida, H., Ohkawa, K., Kanto, T., Hiramatsu, N., Yin, X. M., Hennighausen, L., Tatsumi, T., and Hayashi, N. (2009) Hepatology 50, 1217-1226
22. Takehara, T., Tatsumi, T., Suzuki, T., Rucker, E. B., 3rd, Hennighausen, L., Jinushi, M., Miyagi, T., Kanazawa, Y., and Hayashi, N. (2004) Gastroenterology 127, 1189-1197
23. Tiedt, R., Schomber, T., Hao-Shen, H., and Skoda, R. C. (2007) Blood 109, 1503-1506
24. Yin, X. M., Wang, K., Gross, A., Zhao, Y., Zinkel, S., Klocke, B., Roth, K. A., and Korsmeyer, S. J. (1999) Nature 400, 886-891
25. Gordon, J. W., Scangos, G. A., Plotkin, D. J., Barbosa, J. A., and Ruddle, F. H. (1980) Proc. Natl. Acad. Sci. U. S. A. 77, 7380-7384
26. Takehara, T., and Takahashi, H. (2003) Cancer Res. 63, 3054-3057
27. Feinstein, M. B., and Fraser, C. (1975) J. Gen. Physiol. 66, 561-581
28. Chaiyarit, S., and Thongboonkerd, V. (2009) Anal. Biochem. 394, 249-258
29. Yamagata, H., Shimizu, S., Nishida, Y., Watanabe, Y., Craigen, W. J., and Tsujimoto, Y. (2009) Oncogene 28, 3563-3572
30. Lindsten, T., Ross, A. J., King, A., Zong, W. X., Rathmell, J. C., Shiels, H. A., Ulrich, E., Waymire, K. G., Mahar, P., Frauwirth, K., Chen, Y., Wei, M., Eng, V. M., Adelman, D. M., Simon, M. C., Ma, A., Golden, J. A., Evan, G., Korsmeyer, S. J., MacGregor, G. R., and Thompson, C. B. (2000) Mol. Cell 6, 1389-1399
31. Oltersdorf, T., Elmore, S. W., Shoemaker, A. R., Armstrong, R. C., Augeri, D. J., Belli, B. A., Bruncko, M., Deckwerth, T. L., Dinges, J., Hajduk, P. J., Joseph, M. K., Kitada, S., Korsmeyer, S. J., Kunzer, A. R., Letai, A., Li, C., Mitten, M. J., Nettesheim, D. G., Ng, S., Nimmer, P. M., O'Connor, J. M., Oleksijew, A., Petros, A. M., Reed, J. C., Shen, W., Tahir, S. K., Thompson, C. B., Tomaselli, K. J., Wang, B., Wendt, M. D., Zhang, H., Fesik, S. W., and Rosenberg, S. H. (2005) Nature 435, 677-681
32. Chipuk, J. E., Moldoveanu, T., Llambi, F., Parsons, M. J., and Green, D. R. (2010) Mol. Cell 37, 299-310
33. Hsu, Y. T., and Youle, R. J. (1997) J. Biol. Chem. 272, 13829-13834
34. Wei, M. C., Zong, W. X., Cheng, E. H., Lindsten, T., Panoutsakopoulou, V., Ross, A. J., Roth, K. A., MacGregor, G. R., Thompson, C. B., and Korsmeyer, S. J. (2001) Science 292, 727-730
35. Knudson, C. M., Tung, K. S., Tourtellotte, W. G., Brown, G. A., and Korsmeyer, S. J. (1995) Science 270, 96-99
36. Willis, S. N., Chen, L., Dewson, G., Wei, A., Naik, E., Fletcher, J. I., Adams, J. M., and Huang, D. C. (2005) Genes Dev. 19, 1294-1305
37. Antonsson, B., Montessuit, S., Sanchez, B., and Martinou, J. C. (2001) J. Biol. Chem. 276, 11615-11623
38. Leber, B., Lin, J., and Andrews, D. W. (2007) Apoptosis 12, 897-911
39. Gavathiotis, E., Suzuki, M., Davis, M. L., Pitter, K., Bird, G. H., Katz, S. G., Tu, H. C., Kim, H., Cheng, E. H., Tjandra, N., and Walensky, L. D. (2008) Nature 455, 1076-1081
40. Lovell, J. F., Billen, L. P., Bindner, S., Shamas-Din, A., Fradin, C., Leber, B., and Andrews, D. W. (2008) Cell 135, 1074-1084
41. Print, C. G., Loveland, K. L., Gibson, L., Meehan, T., Stylianou, A., Wreford, N., de Kretser, D., Metcalf, D., Köntgen, F., Adams, J. M., and Cory, S. (1998) Proc. Natl. Acad. Sci. U. S. A. 95, 12424-12431
42. Ross, A. J., Waymire, K. G., Moss, J. E., Parlow, A. F., Skinner, M. K., Russell, L. D., and MacGregor, G. R. (1998) Nat. Genet. 18, 251-256
43. Veis, D. J., Sorenson, C. M., Shutter, J. R., and Korsmeyer, S. J. (1993) Cell 75, 229-240
44. Hamasaki, A., Sendo, F., Nakayama, K., Ishida, N., Negishi, I., Nakayama, K., and Hatakeyama, S. (1998) J. Exp. Med. 188, 1985-1992
45. Dzhagalov, I., Dunkle, A., and He, Y. W. (2008) J. Immunol. 181, 521-528
46. Jabbour, A. M., Heraud, J. E., Daunt, C. P., Kaufmann, T., Sandow, J., O'Reilly, L. A., Callus, B. A., Lopez, A., Strasser, A., Vaux, D. L., and Ekert, P. G. (2009) Cell Death Differ. 16, 555-563