Pharmacological characterization of adenylyl cyclase isoforms in rabbit kidney membranes

Naunyn-Schmiedeberg's Archives of Pharmacology

Volumn 383, Issue 4, 2011, Pages 357-372

  Erdorf, Miriam ^a   Seifert, Roland ^b  

^a UNIVERSITY OF REGENSBURG   (Germany)

^b HANNOVER MEDICAL SCHOOL   (Germany)

Author keywords

Adenylyl cyclase; Glucagon; Kidney cortex; Kidney medulla; MANT nucleotides; Polycystic kidney disease

Indexed keywords

2'(3') O (N METHYLANTHRANILOYL)NUCLEOTIDE; ADENYLATE CYCLASE; ADENYLATE CYCLASE 1; ADENYLATE CYCLASE 5; ARGIPRESSIN; CALCIUM ION; CATECHOLAMINE; GLUCAGON; ISOENZYME; MAGNESIUM ION; NUCLEOTIDE; UNCLASSIFIED DRUG;

ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; ENZYME ACTIVATION; ENZYME INHIBITION; ENZYME KINETICS; ENZYME REGULATION; EXPERIMENTAL RABBIT; KIDNEY; KIDNEY CORTEX; KIDNEY MEDULLA; MALE; NONHUMAN; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION;

ADENYLATE CYCLASE; ANIMALS; CALCIUM; CYCLIC AMP; ENZYME INHIBITORS; KIDNEY CORTEX; KIDNEY MEDULLA; MALE; MEMBRANES; POLYCYSTIC KIDNEY DISEASES; PROTEIN ISOFORMS; RABBITS; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION;

EID: 79954605543     PISSN: 00281298     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00210-011-0600-7     Document Type: Article

References (56)

1. L Barajas L Liu K Powers 1992 Anatomy of the renal innervation: intrarenal aspects and ganglia of origin Can J Physiol Pharmacol 70 735 749 1423018 1:STN:280:DyaK3s%2FksFOqsg%3D%3D
2. MJ Bek S Zheng J Xu I Yamaguchi LD Asico XG Sun PA Jose 2001 Differential expression of adenylyl cyclases in the rat nephron Kidney Int 60 890 899 11532084 10.1046/j.1523-1755.2001.060003890.x 1:CAS:528:DC%2BD3MXmvFKjt70%3D (Pubitemid 34205789)
3. FA Belibi CL Edelstein 2010 Novel targets for the treatment of autosomal dominant polycystic kidney disease Expert Opin Investig Drugs 19 315 328 20141351 10.1517/13543781003588491 1:CAS:528:DC%2BC3cXhvFKnu70%3D
4. MM Bradford 1976 A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding Anal Biochem 72 248 254 942051 10.1016/0003-2697(76)90527-3 1:CAS:528: DyaE28XksVehtrY%3D
5. D Chabardés M Imbert-Teboul M Montegut A Clique F Morel 1975 Catecholamine sensitive adenylate cyclase activity in different segments of the rabbit nephron Pflüger's Arch 361 9 15 10.1007/BF00587334
6. 2+-inhibitable adenylyl cyclases along the renal tubule. Functional consequences for regulation of the cAMP content J Biol Chem 271 19264 19271 8702608 10.1074/jbc.271.32. 19264 (Pubitemid 26271593)
7. J Cheng JP Grande 2007 Cyclic nucleotide phosphodiesterase (PDE) inhibitors: novel therapeutic agents for progressive renal disease Exp Biol Med (Maywood) 232 38 51 1:CAS:528:DC%2BD2sXmslaqug%3D%3D (Pubitemid 46089939)
8. 2+-sensitive adenylyl cyclases by calcium ion in vitro and in vivo Methods enzymol 238 71 81 7799804 10.1016/0076-6879(94)38007-4 1:CAS:528:DyaK2MXit1Wjt7g%3D
9. DM Cooper 2003 Regulation and organization of adenylyl cyclases and cAMP Biochem J 375 517 529 12940771 10.1042/BJ20031061 1:CAS:528:DC%2BD3sXotlehsr0%3D (Pubitemid 37433500)
10. 2+-sensitive adenylyl cyclases Cell Signal 6 823 840 7718403 10.1016/0898-6568(94)90016-7 1:CAS:528: DyaK2MXkt1Cltro%3D
11. N Defer M Best-Belpomme J Hanoune 2000 Tissue specificity and pharmacological relevance of various isoforms of adenylyl cyclase Am J Physiol Renal Physiol 279 F400 F416 10966920 1:CAS:528:DC%2BD3cXmvFSjs7g%3D
12. I Espinasse V Iourgenko N Defer F Samson J Hanoune JJ Mercadier 1995 Type V, but not type VI, adenylyl cyclase mRNA accumulates in the rat heart during ontogenic development. Correlation with increased global adenylyl cyclase activity J Mol Cell Cardiol 27 1789 1795 8523440 10.1016/0022-2828(95)90002-0 1:CAS:528:DyaK2MXotFWmt74%3D
13. AR Gallagher S Hidaka N Gretz R Witzgall 2002 Molecular basis of autosomal-dominant polycystic kidney disease Cell Mol Life Sci 59 682 693 12022474 10.1007/s00018-002-8457-z 1:CAS:528:DC%2BD38XjtlWmtbY%3D (Pubitemid 34457541)
14. BN Gao AG Gilman 1991 Cloning and expression of a widely distributed (type IV) adenylyl cyclase Proc Natl Acad Sci U S A 88 10178 10182 1946437 10.1073/pnas.88.22.10178 1:CAS:528:DyaK3sXhs1CjsL8%3D (Pubitemid 21915798)
15. 2 receptor antagonist Nat Med 9 1323 1326 14502283 10.1038/nm935 1:CAS:528: DC%2BD3sXns1Cksr4%3D (Pubitemid 37279858)
16. U Gether JA Ballesteros R Seifert E Sanders-Bush H Weinstein BK Kobilka 1997 Structural instability of a constitutively active G-protein-coupled receptor. Agonist-independent activation due to conformational flexibility J Biol Chem 272 2587 2590 9006889 10.1074/jbc.272.5.2587 1:CAS:528: DyaK2sXpslehtA%3D%3D (Pubitemid 27053295)
17. A Gille GH Lushington TC Mou MB Doughty RA Johnson R Seifert 2004 Differential inhibition of adenylyl cyclase isoforms and soluble guanylyl cyclase by purine and pyrimidine nucleotides J Biol Chem 279 19955 19969 14981084 10.1074/jbc.M312560200 1:CAS:528:DC%2BD2cXjs1Whsr0%3D (Pubitemid 38623438)
18. M Göttle J Geduhn B König A Gille K Höcherl R Seifert 2009 Characterization of mouse heart adenylyl cyclase J Pharmacol Exp Ther 329 1156 1165 19307450 10.1124/jpet.109.150953
19. JJ Grantham 1997 Polycystic kidney disease: huge kidneys, huge problems, huge progress Trans Am Clin Climatol Assoc 108 165 170 9108675 1:STN:280:DyaK2s3mt1aqsA%3D%3D discussion 170-172
20. N Gretz B Kränzlin R Pey G Schieren J Bach N Obermüller I Ceccherini I Klöting P Rohmeiss S Bachmann M Hafner 1996 Rat models of autosomal dominant polycystic kidney disease Nephrol Dial Transplant 6 46 51 Suppl 11 (Pubitemid 27055657)
21. JL Guillou H Nakata DM Cooper 1999 Inhibition by calcium of mammalian adenylyl cyclases J Biol Chem 274 35539 35545 10585428 10.1074/jbc.274.50.35539 1:CAS:528:DyaK1MXotVGnsL0%3D (Pubitemid 129512849)
22. K Hanaoka WB Guggino 2000 cAMP regulates cell proliferation and cyst formation in autosomal polycystic kidney disease cells J Am Soc Nephrol 11 1179 1187 10864573 1:CAS:528:DC%2BD3cXltFOjtbo%3D (Pubitemid 30416213)
23. C Heliés-Toussaint L Aarab JM Gasc JM Verbavatz D Chabardés 2000 Cellular localization of type 5 and type 6 ACs in collecting duct and regulation of cAMP synthesis Am J Physiol Renal Physiol 279 F185 F194 10894801
24. q-protein coupling J Neurochem 80 678 696 11841575 10.1046/j.0022-3042.2001.00746.x 1:CAS:528:DC%2BD38XhslyisLk%3D (Pubitemid 34809976)
25. 2+ of AC5 revealed by mutants and chimeric constructs J Biol Chem 277 33139 33147 12065575 10.1074/jbc.M112373200 1:CAS:528:DC%2BD38Xnt1Sltr4%3D (Pubitemid 34984831)
26. KS Kim J Kim SK Back JY Im HS Na PL Han 2007 Markedly attenuated acute and chronic pain responses in mice lacking adenylyl cyclase-5 Genes Brain Behav 6 120 127 17410641 10.1111/j.1601-183X.2006.00238.x 1:CAS:528: DC%2BD2sXksFWlsrs%3D (Pubitemid 46328583)
27. OH Lowry NJ Rosebrough AL Farr RJ Randall 1951 Protein measurement with the Folin phenol reagent J Biol Chem 193 265 275 14907713 1:CAS:528: DyaG38XhsVyrsw%3D%3D
28. MG Ludwig K Seuwen 2002 Characterization of the human adenylyl cyclase gene family: cDNA, gene structure, and tissue distribution of the nine isoforms J Recept Signal Transduct Res 22 79 110 12503609 10.1081/RRS-120014589 1:CAS:528:DC%2BD38Xps1ejsrY%3D (Pubitemid 36169141)
29. P Madsen LB Knudsen FC Wiberg RD Carr 1998 Discovery and structure-activity relationship of the first non-peptide competitive human glucagon receptor antagonists J Med Chem 41 5150 5157 9857085 10.1021/jm9810304 1:CAS:528:DyaK1cXnsV2ksbk%3D (Pubitemid 29016309)
30. 2+ levels Am J Physiol 268 F1070 F1080 7611448 1:CAS:528:DyaK2MXmvVyjsr8%3D
31. 2+/calmodulin of type 1 and 8 adenylyl cyclases support their different physiological roles J Biol Chem 284 4451 4463 19029295 10.1074/jbc.M807359200 1:CAS:528:DC%2BD1MXhsFOjsrg%3D
32. B Meister A Dagerlind AP Nicholas T Hokfelt 1994 Patterns of messenger RNA expression for adrenergic receptor subtypes in the rat kidney J Pharmacol Exp Ther 268 1605 1611 8138972 1:CAS:528:DyaK2cXitlKqsrs%3D (Pubitemid 24100384)
33. TC Mou A Gille DA Fancy R Seifert SR Sprang 2005 Structural basis for the inhibition of mammalian membrane adenylyl cyclase by 2'(3')-O-(N- methylanthraniloyl)-guanosine 5'-triphosphate J Biol Chem 280 7253 7261 15591060 10.1074/jbc.M409076200 1:CAS:528:DC%2BD2MXhsFSjsrw%3D (Pubitemid 40341283)
34. MC Ortíz-Capisano PA Ortíz P Harding JL Garvin WH Beierwaltes 2007 Decreased intracellular calcium stimulates renin release via calcium-inhibitable adenylyl cyclase Hypertension 49 162 169 17088449 10.1161/01.HYP.0000250708.04205.d4 (Pubitemid 46360356)
35. TB Patel Z Du S Pierre L Cartin K Scholich 2001 Molecular biological approaches to unravel adenylyl cyclase signaling and function Gene 269 13 25 11376933 10.1016/S0378-1119(01)00448-6 1:CAS:528:DC%2BD3MXjs1yqsbY%3D (Pubitemid 32488902)
36. JP Pieroni A Harry J Chen O Jacobowitz RP Magnusson R Iyengar 1995 Distinct characteristics of the basal activities of adenylyl cyclases 2 and 6 J Biol Chem 270 21368 21373 7673172 10.1074/jbc.270.36.21368 1:CAS:528: DyaK2MXnvFKltrg%3D
37. C Pinto D Papa M Hübner TC Mou GH Lushington R Seifert 2008 Activation and inhibition of adenylyl cyclase isoforms by forskolin analogs J Pharmacol Exp Ther 325 27 36 18184830 10.1124/jpet.107.131904 1:CAS:528:DC%2BD1cXktFGjt7w%3D (Pubitemid 351439155)
38. RT Premont J Chen HW Ma M Ponnapalli R Iyengar 1992 Two members of a widely expressed subfamily of hormone-stimulated adenylyl cyclase Proc Natl Acad Sci U S A 89 9809 9813 1409703 10.1073/pnas.89.20.9809 1:CAS:528: DyaK3sXkvV2ru74%3D
39. 4-receptor Biochemistry 48 1424 1438 19166345 10.1021/bi802050d 1:CAS:528:DC%2BD1MXpslyqsQ%3D%3D
40. F Schweda U Friis C Wagner O Skott A Kurtz 2007 Renin release Physiology (Bethesda) 22 310 319 1:CAS:528:DC%2BD2sXhtlelsbnN
41. R Seifert TW Lee VT Lam BK Kobilka 1998 Reconstitution of β2-adrenoceptor-GTP-binding-protein interaction in Sf9 cells-high coupling efficiency in a β2-adrenoceptor-GSα fusion protein Eur J Biochem 255 369 382 9716378 10.1046/j.1432-1327.1998.2550369.x 1:CAS:528:DyaK1cXkvVOgtb0%3D (Pubitemid 28340245)
42. T Shen Y Suzuki M Poyard N Miyamoto N Defer J Hanoune 1997 Expression of adenylyl cyclase mRNAs in the adult, in developing and in the Brattleboro rat kidney Am J Physiol 273 C323 C330 9252471 1:CAS:528:DyaK2sXlt1Srs70%3D
43. PJ Störk JM Schmitt 2002 Crosstalk between cAMP and MAP kinase signaling in the regulation of cell proliferation Trends Cell Biol 12 258 266 12074885 10.1016/S0962-8924(02)02294-8 (Pubitemid 34634174)
44. RK Sunahara R Taussig 2002 Isoforms of mammalian adenylyl cyclase: multiplicities of signaling Mol Interv 2 168 184 14993377 10.1124/mi.2.3.168 1:CAS:528:DC%2BD3sXpsVWg
45. WE Sweeney Jr ED Avner 2006 Molecular and cellular pathophysiology of autosomal recessive polycystic kidney disease (ARPKD) Cell Tissue Res 326 671 685 16767405 10.1007/s00441-006-0226-0 1:CAS:528:DC%2BD28Xht1entLjM (Pubitemid 44786367)
46. HM Taha J Schmidt M Göttle S Suryanarayana Y Shen WJ Tang A Gille J Geduhn B König S Dove R Seifert 2009 Molecular analysis of the interaction of anthrax adenylyl cyclase toxin, edema factor, with 2â(3â)-O-(N- (methyl)anthraniloyl)-substituted purine and pyrimidine nucleotides Mol Pharmacol 75 693 703 19056899 10.1124/mol.108.052340 1:CAS:528: DC%2BD1MXis1ajs7o%3D
47. 2+ inhibits AVP-dependent cAMP production in thick ascending limbs of Henle Am J Physiol 250 F770 F776 3010737 1:CAS:528:DyaL28XktVWjs78%3D
48. WJ Tang J Krupinski AG Gilman 1991 Expression and characterization of calmodulin-activated (type I) adenylylcyclase J Biol Chem 266 8595 8603 2022671 1:CAS:528:DyaK3MXktVersL0%3D (Pubitemid 21906551)
49. D Tiniakos V Anagnostou S Stavrakis D Karandrea E Agapitos C Kittas 2004 Ontogeny of intrinsic innervation in the human kidney Anat Embryol (Berl) 209 41 47 10.1007/s00429-004-0420-3 1:CAS:528:DC%2BD2cXhtVShsL3F (Pubitemid 40064371)
50. K Tobise Y Ishikawa SR Holmer MJ Im JB Newell H Yoshie M Fujita EE Susannie CJ Homcy 1994 Changes in type VI adenylyl cyclase isoform expression correlate with a decreased capacity for cAMP generation in the aging ventricle Circ Res 74 596 603 8137496 1:CAS:528:DyaK2cXisVWjtLs%3D (Pubitemid 24088520)
51. VE Torres 2004 Cyclic AMP, at the hub of the cystic cycle Kidney Int 66 1283 1285 15327429 10.1111/j.1523-1755.2004.00945.x (Pubitemid 39121040)
52. VE Torres PC Harris Y Pirson 2007 Autosomal dominant polycystic kidney disease Lancet 369 1287 1301 17434405 10.1016/S0140-6736(07)60601-1 (Pubitemid 46552051)
53. SF Vatner L Yan Y Ishikawa DE Vatner J Sadoshima 2009 Adenylyl cyclase type 5 disruption prolongs longevity and protects the heart against stress Circ J 73 195 200 19106458 10.1253/circj.CJ-08-0957 1:CAS:528:DC%2BD1MXis1Wmur8%3D
54. 2 receptor antagonists OPC-31260 and OPC-41061 on polycystic kidney disease development in the PCK rat J Am Soc Nephrol 16 846 851 15728778 10.1681/ASN.2004121090 1:CAS:528:DC%2BD2MXjsVWqsLc%3D (Pubitemid 41710293)
55. Z Xia EJ Choi F Wang C Blazynski DR Storm 1993 Type 1 calmodulin-sensitive adenylyl cyclase is neural specific J Neurochem 60 305 311 8417150 10.1111/j.1471-4159.1993.tb05852.x 1:CAS:528:DyaK3sXpvVKnsQ%3D%3D (Pubitemid 23006732)
56. 2+-stimulated basal adenylyl cyclase activity localization in membrane lipid microdomains of cardiac sinoatrial nodal pacemaker cells J Biol Chem 283 14461 14468 18356168 10.1074/jbc.M707540200 1:CAS:528: DC%2BD1cXlvFyjs7Y%3D