Enzyme-based amperometric platform to determine the polymorphic response in drug metabolism by cytochromes P450

Analytical Chemistry

Volumn 83, Issue 6, 2011, Pages 2179-2186

  Panicco, Paola ^a   Dodhia, Vikash R ^a   Fantuzzi, Andrea ^a   Gilardi, Gianfranco ^b  

^a IMPERIAL COLLEGE LONDON   (United Kingdom)

^b UNIVERSITY OF TURIN   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

AMPEROMETRIC; CATALYTIC ACTIVITY; CYTOCHROME P450; CYTOCHROMES P450; DESULFOVIBRIO VULGARIS; DRUG METABOLISMS; ELECTRODE SURFACES; FLAVODOXIN; GENETIC CHARACTERIZATION; PERSONALIZED MEDICINES; RELIABLE MEASUREMENT;

CATALYST ACTIVITY; ENZYME ELECTRODES; ENZYMES; GENES; HEALTH CARE; METABOLISM; PHYSIOLOGY;

DRUG DOSAGE;

CYTOCHROME P450; DRUG;

ALLELE; ARTICLE; BIOCATALYSIS; CHEMICAL STRUCTURE; CHEMISTRY; ELECTROCHEMISTRY; GENETIC POLYMORPHISM; GENETICS; GENOTYPE; HUMAN; METABOLISM; OXIDATION REDUCTION REACTION; PERSONALIZED MEDICINE; PROTEIN CONFORMATION; PROTEIN ENGINEERING;

ALLELES; BIOCATALYSIS; CYTOCHROME P-450 ENZYME SYSTEM; ELECTROCHEMISTRY; GENOTYPE; HUMANS; INDIVIDUALIZED MEDICINE; MODELS, MOLECULAR; OXIDATION-REDUCTION; PHARMACEUTICAL PREPARATIONS; POLYMORPHISM, GENETIC; PROTEIN CONFORMATION; PROTEIN ENGINEERING;

EID: 79954583659     PISSN: 00032700     EISSN: None     Source Type: Journal    
DOI: 10.1021/ac200119b     Document Type: Article

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