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Volumn 18, Issue 4, 2009, Pages 833-841

Limonene and its oxyfunctionalized compounds: Biotransformation by microorganisms and their role as functional bioactive compounds

Author keywords

Anticancer activity; Biological property; Biotransformation; Limonene; Limonene derivatives

Indexed keywords

ANTICANCER ACTIVITIES; BIOLOGICAL PROPERTY; BIOTRANSFORMATION; LIMONENE; LIMONENE DERIVATIVES;

EID: 79954570418     PISSN: 12267708     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Review
Times cited : (22)

References (63)
  • 1
    • 79954594514 scopus 로고    scopus 로고
    • U.S. Ag, LLC-100%, Available from, Accessed on Sep. 9
    • U.S. Ag, LLC-100% Nature Friendly Agriculture. Available from: http://www.unitedstatesag.org. Accessed on Sep. 9, 2008.
    • (2008) Nature Friendly Agriculture
  • 4
    • 0013944308 scopus 로고
    • Microbiological transformations of terpenes. VIII. Fermentation of limonene in a soil pseudomonad
    • Dhavalikar RS, Bhattacharyya PK. Microbiological transformations of terpenes. VIII. Fermentation of limonene in a soil pseudomonad. Ind. J. Biochem. 3: 144-157 (1966)
    • (1966) Ind. J. Biochem , vol.3 , pp. 144-157
    • Dhavalikar, R.S.1    Bhattacharyya, P.K.2
  • 5
    • 0013947350 scopus 로고
    • Microbiological transformations of terpenes. IX. Pathways of degradation of limonene in a soil pseudomonad
    • Dhavalikar RS, Rangachari PN, Bhattacharyya PK. Microbiological transformations of terpenes. IX. Pathways of degradation of limonene in a soil pseudomonad. Ind. J. Biochem. 3: 158-164 (1966)
    • (1966) Ind. J. Biochem , vol.3 , pp. 158-164
    • Dhavalikar, R.S.1    Rangachari, P.N.2    Bhattacharyya, P.K.3
  • 6
    • 33746876318 scopus 로고    scopus 로고
    • Production of R-(+)-α-terpineol by the biotransformation of limonene from orange essential oil, using cassava waste water as medium
    • Maróstica-Jr MR, Pastore GM. Production of R-(+)-α-terpineol by the biotransformation of limonene from orange essential oil, using cassava waste water as medium. Food Chem. 101: 345-350 (2007)
    • (2007) Food Chem , vol.101 , pp. 345-350
    • Maróstica Jr, M.R.1    Pastore, G.M.2
  • 7
    • 0000979745 scopus 로고
    • Bioconversion of citrus d-limonene
    • Rouseff RL, Leahy MM (eds). ACS Symp. Series No., American Chemical Society, Washington, DC, USA
    • Braddock RJ, Cadwallader KR. Bioconversion of citrus d-limonene. pp. 142-148. In: Fruit Flavors: Biogenesis, Characterization, and Authentication. Rouseff RL, Leahy MM (eds). ACS Symp. Series No. 596. American Chemical Society, Washington, DC, USA (1995)
    • (1995) Fruit Flavors: Biogenesis, Characterization, and Authentication , Issue.596 , pp. 142-148
    • Braddock, R.J.1    Cadwallader, K.R.2
  • 8
    • 33947608924 scopus 로고    scopus 로고
    • Biotransformation of limonene: A review of the main metabolic pathways
    • Maróstica-Jr MR, Pastore GM. Biotransformation of limonene: A review of the main metabolic pathways. Quim. Nova 30: 382-387 (2007)
    • (2007) Quim. Nova , vol.30 , pp. 382-387
    • Maróstica Jr, M.R.1    Pastore, G.M.2
  • 9
    • 0032980875 scopus 로고    scopus 로고
    • Prevention and therapy of cancer by dietary monoterpenes
    • Crowell PL. Prevention and therapy of cancer by dietary monoterpenes J. Nutr. 129: 775S-778S (1999)
    • (1999) J. Nutr , vol.129
    • Crowell, P.L.1
  • 10
    • 0032924489 scopus 로고    scopus 로고
    • Rhodococcus erythropolis DCL14 contains a novel degradation pathway for limonene
    • Van der Werf MJ, Swarts HJ, De Bont JAM. Rhodococcus erythropolis DCL14 contains a novel degradation pathway for limonene. Appl. Environ. Microb. 65: 2092-2102 (1999)
    • (1999) Appl. Environ. Microb , vol.65 , pp. 2092-2102
    • Van der, W.M.J.1    Swarts, H.J.2    de Bont, J.A.M.3
  • 11
    • 0034736403 scopus 로고    scopus 로고
    • Xanthobacter sp C20 contains a novel bioconversion pathway for limonene
    • Van der Werf, MJ, Keijzer PM, Van der Schaft PH. Xanthobacter sp C20 contains a novel bioconversion pathway for limonene. J. Biotechnol. 84: 133-143 (2000)
    • (2000) J. Biotechnol , vol.84 , pp. 133-143
    • Van der, W.M.J.1    Keijzer, P.M.2    Van der, S.P.H.3
  • 12
    • 79954609640 scopus 로고    scopus 로고
    • University of Minnesota, Available from, Accessed on Sep
    • University of Minnesota. Biocatalysis, biodegradation Database. Available from: http://umbbd.msi.umn.edu/. Accessed on Sep. 9, 2008.
    • (2008) Biocatalysis, Biodegradation Database , vol.9
  • 13
    • 0031760535 scopus 로고    scopus 로고
    • Limonene bioconversion to high concentrations of a single and stable product, perillic acid, by a solvent-resistant Pseudomonas putida strain
    • Speelmans G, Bijlsma A, Eggink G. Limonene bioconversion to high concentrations of a single and stable product, perillic acid, by a solvent-resistant Pseudomonas putida strain. Appl. Microbiol. Biot. 50: 538-544 (1998)
    • (1998) Appl. Microbiol. Biot , vol.50 , pp. 538-544
    • Speelmans, G.1    Bijlsma, A.2    Eggink, G.3
  • 14
    • 0035019684 scopus 로고    scopus 로고
    • Biotransformation of limonene by Pseudomonas putida
    • Chatterjee T, Bhattacharyya DK. Biotransformation of limonene by Pseudomonas putida. Appl. Microbiol. Biot. 55: 541-546 (2001)
    • (2001) Appl. Microbiol. Biot , vol.55 , pp. 541-546
    • Chatterjee, T.1    Bhattacharyya, D.K.2
  • 15
    • 0001720038 scopus 로고
    • Biotransformation of limonene and related compounds by Aspergillus cellulosae
    • Noma Y, Yamasaki S, Asakawa Y. Biotransformation of limonene and related compounds by Aspergillus cellulosae. Phytochemistry 31: 2725-2727 (1992)
    • (1992) Phytochemistry , vol.31 , pp. 2725-2727
    • Noma, Y.1    Yamasaki, S.2    Asakawa, Y.3
  • 16
    • 17644372780 scopus 로고    scopus 로고
    • A novel psychrotrophic fungus, Mortierella minutissima, for d-limonene biotransformation
    • Trytek M, Fiedurek J. A novel psychrotrophic fungus, Mortierella minutissima, for d-limonene biotransformation. Biotechnol. Lett. 27: 149-153 (2005)
    • (2005) Biotechnol. Lett , vol.27 , pp. 149-153
    • Trytek, M.1    Fiedurek, J.2
  • 17
    • 49649122236 scopus 로고    scopus 로고
    • Fungal biotransformation of monoterpenes found in agroiindustrial residues from orange and pulp industries into aroma compounds: Screening using solid phase microextraction
    • Marostica-Jr MR, Mota NO, Baudet N, Pastore GM. Fungal biotransformation of monoterpenes found in agroiindustrial residues from orange and pulp industries into aroma compounds: Screening using solid phase microextraction. Food Sci. Biotechnol. 16: 37-42 (2007)
    • (2007) Food Sci. Biotechnol , vol.16 , pp. 37-42
    • Marostica Jr, M.R.1    Mota, N.O.2    Baudet, N.3    Pastore, G.M.4
  • 18
    • 0022572793 scopus 로고
    • Microbial transformations of terpenoids with 1-p-menthene skeleton
    • Abraham WR, Stumpf B, Kieslich K. Microbial transformations of terpenoids with 1-p-menthene skeleton. Appl. Microbiol. Biot. 24: 24-30 (1986)
    • (1986) Appl. Microbiol. Biot , vol.24 , pp. 24-30
    • Abraham, W.R.1    Stumpf, B.2    Kieslich, K.3
  • 19
    • 0035858424 scopus 로고    scopus 로고
    • Biotransformation of (R)-(+)- and (S)-(-)-limonene by fungi and the use of solid phase microextraction for screening
    • Demyttenaere JCR, van Belleghem K, De Kimpe N. Biotransformation of (R)-(+)- and (S)-(-)-limonene by fungi and the use of solid phase microextraction for screening. Phytochemistry 57: 199-208 (2001)
    • (2001) Phytochemistry , vol.57 , pp. 199-208
    • Demyttenaere, J.C.R.1    van Belleghem, K.2    de Kimpe, N.3
  • 20
    • 0033025939 scopus 로고    scopus 로고
    • Biotransformation of citronellol by the basidiomycete Cystoderma carcharias in a aerated-membrane bioreactor
    • Onken J, Berger RG. Biotransformation of citronellol by the basidiomycete Cystoderma carcharias in a aerated-membrane bioreactor. Appl. Microbiol. Biot. 51: 158-163 (1999)
    • (1999) Appl. Microbiol. Biot , vol.51 , pp. 158-163
    • Onken, J.1    Berger, R.G.2
  • 21
    • 0000218883 scopus 로고
    • Potential by-products from microbial transformation of D-limonene
    • Bowen ER. Potential by-products from microbial transformation of D-limonene. Florida State Horticult. Soc., USA 88: 304-308 (1975)
    • (1975) Florida State Horticult. Soc., USA , vol.88 , pp. 304-308
    • Bowen, E.R.1
  • 22
    • 0033179201 scopus 로고    scopus 로고
    • Regiospecific cytochrome P450 limonene hydroxylases from mint (mentha) species: CDNA isolation, characterization, and functional expression of (-)-4Slimonene-3-hydroxylase and (-)-4S-limonene-6-hydroxylase
    • Lupien S, Karp F, Wildung M, Croteau R. Regiospecific cytochrome P450 limonene hydroxylases from mint (mentha) species: cDNA isolation, characterization, and functional expression of (-)-4Slimonene-3-hydroxylase and (-)-4S-limonene-6-hydroxylase. Arch. Biochem. Biophys. 368: 181-192 (1999)
    • (1999) Arch. Biochem. Biophys , vol.368 , pp. 181-192
    • Lupien, S.1    Karp, F.2    Wildung, M.3    Croteau, R.4
  • 23
    • 0032818597 scopus 로고    scopus 로고
    • Biotransformation of (-)- limonene using Solanum aviculare and Dioscorea deltoidea immobilized plant cells
    • Vank T, Valterová I, Vaková R, Vaisar T. Biotransformation of (-)- limonene using Solanum aviculare and Dioscorea deltoidea immobilized plant cells. Biotechnol. Lett. 21: 625-628 (1999)
    • (1999) Biotechnol. Lett , vol.21 , pp. 625-628
    • Vank, T.1    Valterová, I.2    Vaková, R.3    Vaisar, T.4
  • 24
    • 0035377316 scopus 로고    scopus 로고
    • Biotransformation of D-limonene to (+) trans-carveol by toluenegrown Rhodococcus opacus PWD4 cells
    • Duetz WA, Fjällman AHM, Ren S, Jourdat C, Witholt B. Biotransformation of D-limonene to (+) trans-carveol by toluenegrown Rhodococcus opacus PWD4 cells. Appl. Environ. Microb. 67: 2829-2832 (2001)
    • (2001) Appl. Environ. Microb , vol.67 , pp. 2829-2832
    • Duetz, W.A.1    Fjällman, A.H.M.2    Ren, S.3    Jourdat, C.4    Witholt, B.5
  • 25
    • 0002334864 scopus 로고
    • Conversion of D-limonene into an optically active isomer of α-terpineol by a Cladosporium species
    • Kraidman G, Mukherjee BB, Hill ID. Conversion of D-limonene into an optically active isomer of α-terpineol by a Cladosporium species. Bacteriol. Proc. 69: 63 (1969)
    • (1969) Bacteriol. Proc , vol.69 , pp. 63
    • Kraidman, G.1    Mukherjee, B.B.2    Hill, I.D.3
  • 26
    • 0031883483 scopus 로고    scopus 로고
    • Bioconversion of (R)-(+)- limonene by P. digitatum (NRRL 1202)
    • Tan Q, Day DF, Cadwallader KR. Bioconversion of (R)-(+)- limonene by P. digitatum (NRRL 1202). Process Biochem. 33: 29-37 (1998)
    • (1998) Process Biochem , vol.33 , pp. 29-37
    • Tan, Q.1    Day, D.F.2    Cadwallader, K.R.3
  • 27
    • 0031973443 scopus 로고    scopus 로고
    • Bioconversion of limonene to α-terpineol by immobilized Penicillium digitatum
    • Tan Q, Day DF. Bioconversion of limonene to α-terpineol by immobilized Penicillium digitatum. Appl. Microbiol. Biot. 49: 96-101 (1998)
    • (1998) Appl. Microbiol. Biot , vol.49 , pp. 96-101
    • Tan, Q.1    Day, D.F.2
  • 28
    • 0032170405 scopus 로고    scopus 로고
    • Organic co-solvent effects on the bioconversion of (R)-(+)-limonene to (R)-(+)-alpha-terpineol
    • Tan Q, Day DF. Organic co-solvent effects on the bioconversion of (R)-(+)-limonene to (R)-(+)-alpha-terpineol. Process Biochem 33: 755-761 (1998)
    • (1998) Process Biochem , vol.33 , pp. 755-761
    • Tan, Q.1    Day, D.F.2
  • 29
    • 0037390136 scopus 로고    scopus 로고
    • Biotransformation of (R)-(+)- and (S)-(-)-limonene to α-terpineol by Penicillium digitatum - investigation of the culture conditions
    • Adams A, Demyttenaere JCR, De Kimpe N. Biotransformation of (R)-(+)- and (S)-(-)-limonene to α-terpineol by Penicillium digitatum - investigation of the culture conditions. Food Chem. 80: 525-534 (2003)
    • (2003) Food Chem , vol.80 , pp. 525-534
    • Adams, A.1    Demyttenaere, J.C.R.2    de Kimpe, N.3
  • 30
    • 33750961012 scopus 로고    scopus 로고
    • Biotransformation of citronellol in rose-oxide using cassava wastewater as a medium
    • Maróstica-Jr MR, Pastore GM. Biotransformation of citronellol in rose-oxide using cassava wastewater as a medium. Ciênc. Tecnol. Aliment. 26: 609-696 (2006)
    • (2006) Ciênc. Tecnol. Aliment , vol.26 , pp. 609-696
    • Maróstica-Jr, M.R.1    Pastore, G.M.2
  • 31
  • 34
    • 32144462290 scopus 로고    scopus 로고
    • Antimicrobial activity of the essential oils of various plants against tomato late blight disease agent Phytophthora infestans
    • Soylu EM, Soylu S, Kurt S. Antimicrobial activity of the essential oils of various plants against tomato late blight disease agent Phytophthora infestans. Mycopathology 161: 119-128 (2006)
    • (2006) Mycopathology , vol.161 , pp. 119-128
    • Soylu, E.M.1    Soylu, S.2    Kurt, S.3
  • 35
    • 0037716470 scopus 로고    scopus 로고
    • Identification of aroma active compounds in orange essence oil using gas chromatography-olfactometry and gas chromatography-mass spectrometry
    • Högnadóttir A, Rouseff RL. Identification of aroma active compounds in orange essence oil using gas chromatography-olfactometry and gas chromatography-mass spectrometry. J. Chromatogr. A 998: 201-211 (2003)
    • (2003) J. Chromatogr. A , vol.998 , pp. 201-211
    • Högnadóttir, A.1    Rouseff, R.L.2
  • 36
    • 4544355374 scopus 로고    scopus 로고
    • Volatile flavour components of orange juice obtained from the cv. Kozan of Turkey
    • Selli S, Cabaroglu T, Canbas A. Volatile flavour components of orange juice obtained from the cv. Kozan of Turkey. J. Food Compos. Anal. 17: 789-796 (2004)
    • (2004) J. Food Compos. Anal , vol.17 , pp. 789-796
    • Selli, S.1    Cabaroglu, T.2    Canbas, A.3
  • 37
    • 14944387099 scopus 로고    scopus 로고
    • Antibacterial activity and chemical composition of the essential oil of Grammosciadium platycarpum Boiss
    • Sonboli A, Eftekhar F, Yousefzadi M, Kanani MR. Antibacterial activity and chemical composition of the essential oil of Grammosciadium platycarpum Boiss. from Iran. Z. Naturforsch C 60: 30-34 (2005)
    • (2005) From Iran. Z. Naturforsch C , vol.60 , pp. 30-34
    • Sonboli, A.1    Eftekhar, F.2    Yousefzadi, M.3    Kanani, M.R.4
  • 38
    • 0036100580 scopus 로고    scopus 로고
    • Anti-Listeria monocytogenes activity of essential oils components of conifers
    • Mourey A, Canillac N. Anti-Listeria monocytogenes activity of essential oils components of conifers. Food Control 13: 289-292 (2002)
    • (2002) Food Control , vol.13 , pp. 289-292
    • Mourey, A.1    Canillac, N.2
  • 41
    • 0037570716 scopus 로고    scopus 로고
    • Immunomodulatory activity of naturally occurring monoterpenes carvone, limonene, and perillic acid
    • Raphael TJ, Kuttan G. Immunomodulatory activity of naturally occurring monoterpenes carvone, limonene, and perillic acid. Immunopharm. Immunot. 25: 285-294 (2003)
    • (2003) Immunopharm. Immunot , vol.25 , pp. 285-294
    • Raphael, T.J.1    Kuttan, G.2
  • 43
    • 0036299897 scopus 로고    scopus 로고
    • Distribution and immune responses resulting from oral administration of d-limonene in rats
    • Hamada M, Uezu K, Matsushita J, Yamamoto S, Kishino Y. Distribution and immune responses resulting from oral administration of d-limonene in rats. J. Nutr. Sci. Vitaminol. 48: 155-160 (2002)
    • (2002) J. Nutr. Sci. Vitaminol , vol.48 , pp. 155-160
    • Hamada, M.1    Uezu, K.2    Matsushita, J.3    Yamamoto, S.4    Kishino, Y.5
  • 45
    • 0030867207 scopus 로고    scopus 로고
    • Cancer chemoprevention and therapy by monoterpenes
    • Gould MN. Cancer chemoprevention and therapy by monoterpenes. Environ. Health Persp. 105: 977-979 (1997)
    • (1997) Environ. Health Persp , vol.105 , pp. 977-979
    • Gould, M.N.1
  • 48
    • 6444242718 scopus 로고    scopus 로고
    • Monoterpenes enhanced the sensitivity of head and neck cancer cells to radiation treatment in vitro
    • Samaila D, Toy BJ, Wang RC, Elegbede AJ. Monoterpenes enhanced the sensitivity of head and neck cancer cells to radiation treatment in vitro. Anticancer Res. 24: 3089-3095 (2004)
    • (2004) Anticancer Res , vol.24 , pp. 3089-3095
    • Samaila, D.1    Toy, B.J.2    Wang, R.C.3    Elegbede, A.J.4
  • 49
    • 37849185471 scopus 로고    scopus 로고
    • Anaplastic oligodendroglioma responding favorably to intranasal delivery of perillyl alcohol: A case report and literature review
    • Da Fonseca CO, Masini M, Futuro D, Caetano R, Gattass CR, Quirico-Santos T. Anaplastic oligodendroglioma responding favorably to intranasal delivery of perillyl alcohol: A case report and literature review. Surg. Neurol. 66: 611-615 (2006)
    • (2006) Surg. Neurol , vol.66 , pp. 611-615
    • da Fonseca, C.O.1    Masini, M.2    Futuro, D.3    Caetano, R.4    Gattass, C.R.5    Quirico-Santos, T.6
  • 51
    • 48549098794 scopus 로고    scopus 로고
    • Preliminary results from a phase I/II study of perillyl alcohol intranasal administration in adults with recurrent malignant gliomas
    • Da Fonseca CO, Schwartsmann G, Fischer J, Nagel J, Futuro D, Quirico-Santos T, Gattass CR. Preliminary results from a phase I/II study of perillyl alcohol intranasal administration in adults with recurrent malignant gliomas. Surg. Neurol. 70: 259-267 (2008)
    • (2008) Surg. Neurol , vol.70 , pp. 259-267
    • da Fonseca, C.O.1    Schwartsmann, G.2    Fischer, J.3    Nagel, J.4    Futuro, D.5    Quirico-Santos, T.6    Gattass, C.R.7
  • 53
    • 0028928294 scopus 로고
    • Induction of apoptosis in liver tumors by the monoterpene perillyl alcohol
    • Mills JJ, Chari RS, Boyer IJ, Gould MN, Jirtle RL. Induction of apoptosis in liver tumors by the monoterpene perillyl alcohol. Cancer Res. 55: 979-983 (1995)
    • (1995) Cancer Res , vol.55 , pp. 979-983
    • Mills, J.J.1    Chari, R.S.2    Boyer, I.J.3    Gould, M.N.4    Jirtle, R.L.5
  • 54
    • 0141791063 scopus 로고    scopus 로고
    • Perillyl alcohol and perillaldehyde induced cell cycle arrest and cell death in BroTo and A549 cells cultured in vitro
    • Elegbede JA, Floresa R, Wang RC. Perillyl alcohol and perillaldehyde induced cell cycle arrest and cell death in BroTo and A549 cells cultured in vitro. Life Sci. 73: 2831-2840 (2003)
    • (2003) Life Sci , vol.73 , pp. 2831-2840
    • Elegbede, J.A.1    Floresa, R.2    Wang, R.C.3
  • 55
    • 33644891059 scopus 로고    scopus 로고
    • Perillyl alcohol induces c-Myc-dependent apoptosis in Bcr/Abl-transformed leukemia cells
    • Clark SS. Perillyl alcohol induces c-Myc-dependent apoptosis in Bcr/Abl-transformed leukemia cells. Oncology 70: 13-18 (2006)
    • (2006) Oncology , vol.70 , pp. 13-18
    • Clark, S.S.1
  • 56
    • 0141925956 scopus 로고    scopus 로고
    • Anti-leukemia effect of perillyl alcohol in Bcr/Abl-transformed cells indirectly inhibits signaling through Mek in a Ras- and Rafindependent fashion
    • Clark SS, Zhong L, Filiault D, Perman S, Ren Z, Gould M, Yang X. Anti-leukemia effect of perillyl alcohol in Bcr/Abl-transformed cells indirectly inhibits signaling through Mek in a Ras- and Rafindependent fashion. Clin. Cancer Res. 9: 4494-4504 (2003)
    • (2003) Clin. Cancer Res , vol.9 , pp. 4494-4504
    • Clark, S.S.1    Zhong, L.2    Filiault, D.3    Perman, S.4    Ren, Z.5    Gould, M.6    Yang, X.7
  • 57
    • 33847164134 scopus 로고    scopus 로고
    • Cell cycle arrest by the isoprenoids perillyl alcohol, geraniol, and farnesol is mediated by p21Cip1 and p27Kip1 in human pancreatic adenocarcinoma cells
    • Wiseman DA, Werner SR, Crowell PL. Cell cycle arrest by the isoprenoids perillyl alcohol, geraniol, and farnesol is mediated by p21Cip1 and p27Kip1 in human pancreatic adenocarcinoma cells. J. Pharmacol. Exp. Ther. 320: 1163-1170 (2007)
    • (2007) J. Pharmacol. Exp. Ther , vol.320 , pp. 1163-1170
    • Wiseman, D.A.1    Werner, S.R.2    Crowell, P.L.3
  • 58
    • 0034980637 scopus 로고    scopus 로고
    • Farnesyltransferase inhibitors: Potential role in the treatment of cancer
    • Cox AD. Farnesyltransferase inhibitors: Potential role in the treatment of cancer. Drugs 61: 723-732 (2001)
    • (2001) Drugs , vol.61 , pp. 723-732
    • Cox, A.D.1
  • 60
    • 0029828909 scopus 로고    scopus 로고
    • Identifying differential gene expression in monoterpene-treated mammary carcinomas using subtractive display
    • Ariazi EA, Gould MN. Identifying differential gene expression in monoterpene-treated mammary carcinomas using subtractive display. J. Biol. Chem. 271: 29286-29294 (1996)
    • (1996) J. Biol. Chem , vol.271 , pp. 29286-29294
    • Ariazi, E.A.1    Gould, M.N.2
  • 62
    • 0142074249 scopus 로고    scopus 로고
    • Monoterpene regulation of Ras and Rasrelated protein expression
    • Holstein SA, Hohl RJ. Monoterpene regulation of Ras and Rasrelated protein expression. J. Lipid Res. 44: 1209-1215 (2003)
    • (2003) J. Lipid Res , vol.44 , pp. 1209-1215
    • Holstein, S.A.1    Hohl, R.J.2


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