메뉴 건너뛰기




Volumn 6, Issue 4, 2011, Pages 450-464

Epigenetic reprogramming as a key contributor to melanocyte malignant transformation

Author keywords

Anchorage blockade; Epigenetic reprogramming; Malignant melanoma; Pluripotency; Sustained stress

Indexed keywords

5 AZA 2' DEOXYCYTIDINE; HISTONE; MELAN A; MICRORNA; TRICHOSTATIN A;

EID: 79954477288     PISSN: 15592294     EISSN: 15592308     Source Type: Journal    
DOI: 10.4161/epi.6.4.14917     Document Type: Article
Times cited : (35)

References (59)
  • 1
    • 2642531973 scopus 로고    scopus 로고
    • Epigenetics in human disease and prospects for epigenetic therapy
    • Egger G, Liang G, Aparicio A, Jones PA. Epigenetics in human disease and prospects for epigenetic therapy. Nature 2004; 429:457-63.
    • (2004) Nature , vol.429 , pp. 457-463
    • Egger, G.1    Liang, G.2    Aparicio, A.3    Jones, P.A.4
  • 2
    • 0036324032 scopus 로고    scopus 로고
    • DNA hypomethylation, cancer, the immunodeficiency, centromeric region instability, facial anomalies syndrome and chromosomal rearrangements
    • Ehrlich M. DNA hypomethylation, cancer, the immunodeficiency, centromeric region instability, facial anomalies syndrome and chromosomal rearrangements. J Nutr 2002; 132:2424-9.
    • (2002) J Nutr , vol.132 , pp. 2424-2429
    • Ehrlich, M.1
  • 5
    • 0027504621 scopus 로고
    • Expression of an exogenous eukaryotic DNA methyltransferase gene induces transformation of NIH 3T3 cells
    • Wu J, Issa JP, Herman J, Bassett DE Jr, Nelkin BD, Baylin SB. Expression of an exogenous eukaryotic DNA methyltransferase gene induces transformation of NIH 3T3 cells. Proc Natl Acad Sci USA 1993; 90:8891-5.
    • (1993) Proc Natl Acad Sci USA , vol.90 , pp. 8891-8895
    • Wu, J.1    Issa, J.P.2    Herman, J.3    Bassett Jr., D.E.4    Nelkin, B.D.5    Baylin, S.B.6
  • 6
    • 0033153303 scopus 로고    scopus 로고
    • The human DNA methyltransferases (DNMTs) 1, 3a and 3b: Coordinate mRNA expression in normal tissues and overexpression in tumors
    • Robertson KD, Uzvolgyi E, LIang G, Talmadge C, Sumegi J, Gonzales FA, et al. The human DNA methyltransferases (DNMTs) 1, 3a and 3b: coordinate mRNA expression in normal tissues and overexpression in tumors. Nucleic Acids Res 1999; 27:2291-8.
    • (1999) Nucleic Acids Res , vol.27 , pp. 2291-2298
    • Robertson, K.D.1    Uzvolgyi, E.2    Liang, G.3    Talmadge, C.4    Sumegi, J.5    Gonzales, F.A.6
  • 7
    • 27744560484 scopus 로고    scopus 로고
    • DNA methyltransferase-3a interacts with p53 and represses p53-mediated gene expression
    • Wang YA, Kamarova Y, Shen KC, Jiang Z, Hahn MJ, Wang Y, et al. DNA methyltransferase-3a interacts with p53 and represses p53-mediated gene expression. Cancer Biol Ther 2005; 4:1138-43.
    • (2005) Cancer Biol Ther , vol.4 , pp. 1138-1143
    • Wang, Y.A.1    Kamarova, Y.2    Shen, K.C.3    Jiang, Z.4    Hahn, M.J.5    Wang, Y.6
  • 8
    • 77953995002 scopus 로고    scopus 로고
    • Covalent histone modifications: Miswritten, misinterpreted and mis-erased in human cancers
    • Chi P, Allis CD, Wang GG. Covalent histone modifications: miswritten, misinterpreted and mis-erased in human cancers. Nat Rev Cancer 2010; 10:457-69.
    • (2010) Nat Rev Cancer , vol.10 , pp. 457-469
    • Chi, P.1    Allis, C.D.2    Wang, G.G.3
  • 9
    • 67349190247 scopus 로고    scopus 로고
    • Linking DNA methylation and histone modification: Patterns and paradigms
    • Cedar H, Bergman Y. Linking DNA methylation and histone modification: patterns and paradigms. Nat Rev Genet 2009; 10:295-304.
    • (2009) Nat Rev Genet , vol.10 , pp. 295-304
    • Cedar, H.1    Bergman, Y.2
  • 10
    • 33646070846 scopus 로고    scopus 로고
    • A bivalent chromatin structure marks key developmental genes in embryonic stem cells
    • Bernstein BE, Mikkelsen TS, Xie X, Kamal M, Huebert DJ, Cuff J, et al. A bivalent chromatin structure marks key developmental genes in embryonic stem cells. Cell 2006; 125:315-26.
    • (2006) Cell , vol.125 , pp. 315-326
    • Bernstein, B.E.1    Mikkelsen, T.S.2    Xie, X.3    Kamal, M.4    Huebert, D.J.5    Cuff, J.6
  • 11
    • 34547624303 scopus 로고    scopus 로고
    • Genome-wide maps of chromatin state in pluripotent and lineage-committed cells
    • Mikkelsen TS, Ku M, Jaffe DB, Issac B, Lieberman E, Giannoukos G, et al. Genome-wide maps of chromatin state in pluripotent and lineage-committed cells. Nature 2007; 448:553-60.
    • (2007) Nature , vol.448 , pp. 553-560
    • Mikkelsen, T.S.1    Ku, M.2    Jaffe, D.B.3    Issac, B.4    Lieberman, E.5    Giannoukos, G.6
  • 12
    • 34249279527 scopus 로고    scopus 로고
    • Stability and flexibility of epigenetic gene regulation in mammalian development
    • Reik W. Stability and flexibility of epigenetic gene regulation in mammalian development. Nature 2007; 447:425-32.
    • (2007) Nature , vol.447 , pp. 425-432
    • Reik, W.1
  • 13
    • 29244469466 scopus 로고    scopus 로고
    • The epigenetic progenitor origin of human cancer
    • Feinberg AP, Ohlsson R, Henikoff S. The epigenetic progenitor origin of human cancer. Nat Rev Genet 2006; 7:21-33.
    • (2006) Nat Rev Genet , vol.7 , pp. 21-33
    • Feinberg, A.P.1    Ohlsson, R.2    Henikoff, S.3
  • 14
    • 0037436509 scopus 로고    scopus 로고
    • Loss of IGF2 imprinting: A potential marker of colorectal cancer risk
    • Cui H. et al. Loss of IGF2 imprinting: a potential marker of colorectal cancer risk. Science 2003; 299:1753-5.
    • (2003) Science , vol.299 , pp. 1753-1755
    • Cui, H.1
  • 16
    • 33644846509 scopus 로고    scopus 로고
    • Epigenetic gene silencing in cancer-a mechanism for early oncogenic pathway addiction?
    • Baylin SB, Ohm JE. Epigenetic gene silencing in cancer-a mechanism for early oncogenic pathway addiction? Nat Rev Cancer 2006; 6:107-16.
    • (2006) Nat Rev Cancer , vol.6 , pp. 107-116
    • Baylin, S.B.1    Ohm, J.E.2
  • 17
    • 36549085004 scopus 로고    scopus 로고
    • The genome and epigenome of malignant melanoma
    • Dahl C, Guldberg P. The genome and epigenome of malignant melanoma. APMIS 2007; 115:1161-76.
    • (2007) APMIS , vol.115 , pp. 1161-1176
    • Dahl, C.1    Guldberg, P.2
  • 20
    • 77953424645 scopus 로고    scopus 로고
    • Tissue inhibitor of metalloproteinase 1 expression associated with gene demethylation confers anoikis resistance in early phases of melanocyte malignant transformation
    • Ricca TI, Liang G, Suenaga AP, Han SW, Jones PA, Jasiulionis MG. Tissue inhibitor of metalloproteinase 1 expression associated with gene demethylation confers anoikis resistance in early phases of melanocyte malignant transformation. Transl Oncol 2009; 2:329-40.
    • (2009) Transl Oncol , vol.2 , pp. 329-340
    • Ricca, T.I.1    Liang, G.2    Suenaga, A.P.3    Han, S.W.4    Jones, P.A.5    Jasiulionis, M.G.6
  • 21
    • 73949133378 scopus 로고    scopus 로고
    • Telomere-centromere-driven genomic instability contributes to karyotype evolution in a mouse model of melanoma
    • Silva AG, Graves HA, Guffei A, Ricca TI, Mortara RA, Jasiulionis MG, Mai S. Telomere-centromere-driven genomic instability contributes to karyotype evolution in a mouse model of melanoma. Neoplasia 2010; 12:11-9.
    • (2010) Neoplasia , vol.12 , pp. 11-19
    • Silva, A.G.1    Graves, H.A.2    Guffei, A.3    Ricca, T.I.4    Mortara, R.A.5    Jasiulionis, M.G.6    Mai, S.7
  • 22
    • 37149010874 scopus 로고    scopus 로고
    • Oxidative stress modulates DNA methylation by endogenous nitric oxide during cell substrate adhesion blockade
    • Campos AC, Molognoni F, Melo FH, Galdieri LC, Carneiro CR, D'Almeida V, et al. Oxidative stress modulates DNA methylation by endogenous nitric oxide during cell substrate adhesion blockade. Neoplasia 2007; 9:1111-21.
    • (2007) Neoplasia , vol.9 , pp. 1111-1121
    • Campos, A.C.1    Molognoni, F.2    Melo, F.H.3    Galdieri, L.C.4    Carneiro, C.R.5    D'Almeida, V.6
  • 23
    • 0035962631 scopus 로고    scopus 로고
    • DNA methylation, methyltransferases and cancer
    • Robertson KD. DNA methylation, methyltransferases and cancer. Oncogene 2001; 20:3139-55.
    • (2001) Oncogene , vol.20 , pp. 3139-3155
    • Robertson, K.D.1
  • 24
    • 77954469685 scopus 로고    scopus 로고
    • Global DNA hipomethylation: The meaning in carcinogenesis
    • Guz J, Foksinski M, Olinski R. Global DNA hipomethylation: the meaning in carcinogenesis. Postepy Biochem 2010; 56:16-21.
    • (2010) Postepy Biochem , vol.56 , pp. 16-21
    • Guz, J.1    Foksinski, M.2    Olinski, R.3
  • 25
    • 18144419362 scopus 로고    scopus 로고
    • Regulation of DNA methyltransferase 1 by the pRb/E2F1 pathway
    • McCabe MT, Davis JN, Day ML. Regulation of DNA methyltransferase 1 by the pRb/E2F1 pathway. Cancer Res 2005; 65:3624-32.
    • (2005) Cancer Res , vol.65 , pp. 3624-3632
    • McCabe, M.T.1    Davis, J.N.2    Day, M.L.3
  • 26
    • 69249220176 scopus 로고    scopus 로고
    • DNA methylation and methyl-CpG binding proteins: Developmental requirements and function
    • Bogdanovic O, Veenstra GJ. DNA methylation and methyl-CpG binding proteins: developmental requirements and function. Chromosoma 2009; 118:549-65.
    • (2009) Chromosoma , vol.118 , pp. 549-565
    • Bogdanovic, O.1    Veenstra, G.J.2
  • 27
    • 54349095323 scopus 로고    scopus 로고
    • G9a/GLP complexes independently mediate H3K9 and DNA methylation to silence transcription
    • Tachibana M, Matsumura Y, Fukuda M, Kimura H, Shinkai Y. G9a/GLP complexes independently mediate H3K9 and DNA methylation to silence transcription. EMBO J 2008; 27:2681-90.
    • (2008) EMBO J , vol.27 , pp. 2681-2690
    • Tachibana, M.1    Matsumura, Y.2    Fukuda, M.3    Kimura, H.4    Shinkai, Y.5
  • 28
    • 10744230544 scopus 로고    scopus 로고
    • Suv39 h-mediated histone H3 lysine 9 methylation directs DNA methylation to major satellite repeats at pericentric heterochromatin
    • Lehnertz B, Ueda Y, Derijck AA, Braunschweig U, Perez-Burgos L, Kubicek S, et al. Suv39 h-mediated histone H3 lysine 9 methylation directs DNA methylation to major satellite repeats at pericentric heterochromatin. Curr Biol 2003; 13:1192-200.
    • (2003) Curr Biol , vol.13 , pp. 1192-1200
    • Lehnertz, B.1    Ueda, Y.2    Derijck, A.A.3    Braunschweig, U.4    Perez-Burgos, L.5    Kubicek, S.6
  • 29
    • 78449231269 scopus 로고    scopus 로고
    • Multivalent epigenetic marks confer microenvironment-responsive epigenetic plasticity to ovarian cancer cells
    • [Epub ahead of print]
    • Bapat SA, Jin V, Berry N, Balch C, Sharma N, Kurrey N, et al. Multivalent epigenetic marks confer microenvironment-responsive epigenetic plasticity to ovarian cancer cells. Epigenetics 2010; 5; [Epub ahead of print].
    • (2010) Epigenetics , pp. 5
    • Bapat, S.A.1    Jin, V.2    Berry, N.3    Balch, C.4    Sharma, N.5    Kurrey, N.6
  • 30
    • 69949085947 scopus 로고    scopus 로고
    • Histone H3 lysine 4 di-methylation: A novel mark for transcriptional fidelity?
    • Pinskaya M, Morillon A. Histone H3 lysine 4 di-methylation: a novel mark for transcriptional fidelity? Epigenetic 2009; 4:302-6.
    • (2009) Epigenetic , vol.4 , pp. 302-306
    • Pinskaya, M.1    Morillon, A.2
  • 31
    • 0035839136 scopus 로고    scopus 로고
    • Translating the histone code
    • Jenuwein T, Allis CD. Translating the histone code. Science 2001; 293:1074-80.
    • (2001) Science , vol.293 , pp. 1074-1080
    • Jenuwein, T.1    Allis, C.D.2
  • 32
    • 55949136562 scopus 로고    scopus 로고
    • Roles of the EZH2 histone methyltransferase in cancer epigenetics
    • Simon JA, Lange CA. Roles of the EZH2 histone methyltransferase in cancer epigenetics. Mutat Res 2008; 647:21-9.
    • (2008) Mutat Res , vol.647 , pp. 21-29
    • Simon, J.A.1    Lange, C.A.2
  • 33
    • 77953292238 scopus 로고    scopus 로고
    • SIRT1 and p53, effect on cancer, senescence and beyond
    • Yi J, Luo J. SIRT1 and p53, effect on cancer, senescence and beyond. Biochim Biophys Acta 2010; 1804:1684-9.
    • (2010) Biochim Biophys Acta , vol.1804 , pp. 1684-1689
    • Yi, J.1    Luo, J.2
  • 34
    • 77952570482 scopus 로고    scopus 로고
    • Chd1 remodelers maintain open chromatin and regulate the epigenetics of differentiation
    • Persson J, Ekwall K. Chd1 remodelers maintain open chromatin and regulate the epigenetics of differentiation. Exp Cell Res 2010; 316:1316-23.
    • (2010) Exp Cell Res , vol.316 , pp. 1316-1323
    • Persson, J.1    Ekwall, K.2
  • 35
    • 3242663659 scopus 로고    scopus 로고
    • An integrated epigenetic and genetic approach to common human disease
    • Bjornsson HT, Fallin MD, Feinberg AP. An integrated epigenetic and genetic approach to common human disease. Trends Genet 2004; 20:350-8.
    • (2004) Trends Genet , vol.20 , pp. 350-358
    • Bjornsson, H.T.1    Fallin, M.D.2    Feinberg, A.P.3
  • 36
    • 67649470377 scopus 로고    scopus 로고
    • Cancer prevention research-then and now
    • Bode AM, Dong Z. Cancer prevention research-then and now. Nat Rev Cancer 2009; 9:508-16.
    • (2009) Nat Rev Cancer , vol.9 , pp. 508-516
    • Bode, A.M.1    Dong, Z.2
  • 39
    • 67349190247 scopus 로고    scopus 로고
    • Linking DNA methylation and histone modification: Patterns and paradigms
    • Cedar H, Bergman Y. Linking DNA methylation and histone modification: patterns and paradigms. Nat Rev Genet 2009; 10:295-304.
    • (2009) Nat Rev Genet , vol.10 , pp. 295-304
    • Cedar, H.1    Bergman, Y.2
  • 40
    • 27744548525 scopus 로고    scopus 로고
    • Multiple markers for melanoma progression regulated by DNA methylation: Insights from transcriptomic studies
    • Gallagher WM, Bergin OE, Rafferty M, Kelly ZD, Nolan IM, Fox EJ, et al. Multiple markers for melanoma progression regulated by DNA methylation: insights from transcriptomic studies. Carcinogenesis 2005; 26:1856-67.
    • (2005) Carcinogenesis , vol.26 , pp. 1856-1867
    • Gallagher, W.M.1    Bergin, O.E.2    Rafferty, M.3    Kelly, Z.D.4    Nolan, I.M.5    Fox, E.J.6
  • 42
    • 0038147200 scopus 로고    scopus 로고
    • Depsipeptide (FR901228) inhibits proliferation and induces apoptosis in primary and metastatic human uveal melanoma cell lines
    • Klisovic DD, Katz SE, Effron D, Klisovic MI, Wickham J, Parthun MR, et al. Depsipeptide (FR901228) inhibits proliferation and induces apoptosis in primary and metastatic human uveal melanoma cell lines. Invest Ophthalmol Vis Sci 2003; 44:2390-8.
    • (2003) Invest Ophthalmol Vis Sci , vol.44 , pp. 2390-2398
    • Klisovic, D.D.1    Katz, S.E.2    Effron, D.3    Klisovic, M.I.4    Wickham, J.5    Parthun, M.R.6
  • 45
    • 49649125674 scopus 로고    scopus 로고
    • Identification of novel epigenetically modified genes in human melanoma via promoter methylation gene profiling
    • Liu S, Ren S, Howell P, Fodstad O, Riker AI. Identification of novel epigenetically modified genes in human melanoma via promoter methylation gene profiling. Pigment Cell Melanoma Res 2008; 21:545-58.
    • (2008) Pigment Cell Melanoma Res , vol.21 , pp. 545-558
    • Liu, S.1    Ren, S.2    Howell, P.3    Fodstad, O.4    Riker, A.I.5
  • 46
    • 77954505348 scopus 로고    scopus 로고
    • Epithelial-mesenchymal transitions in cancer onset and progression
    • Thiery JP. Epithelial-mesenchymal transitions in cancer onset and progression. Bull Acad Natl Med 2009; 193:1969-78.
    • (2009) Bull Acad Natl Med , vol.193 , pp. 1969-1978
    • Thiery, J.P.1
  • 48
    • 68949136540 scopus 로고    scopus 로고
    • Stem cells: Escaping fates with open states
    • Sims RJ, 3rd, Reinberg D. Stem cells: Escaping fates with open states. Nature 2009; 13:802-3.
    • (2009) Nature , vol.13 , pp. 802-803
    • Sims III, R.J.1    Reinberg, D.2
  • 49
    • 33845645536 scopus 로고    scopus 로고
    • The proteasome restricts permissive transcription at tissue-specific gene loci in embryonic stem cells
    • Szutorisz H, Georgiou A, Tora L, Dillon N. The proteasome restricts permissive transcription at tissue-specific gene loci in embryonic stem cells. Cell 2006; 127:1375-88.
    • (2006) Cell , vol.127 , pp. 1375-1388
    • Szutorisz, H.1    Georgiou, A.2    Tora, L.3    Dillon, N.4
  • 51
    • 0344586043 scopus 로고    scopus 로고
    • Mutagenicity, toxicity and repair of DNA base damage induced by oxidation
    • Bjelland S, Seeberg E. Mutagenicity, toxicity and repair of DNA base damage induced by oxidation. Mutat Res 2003; 531:37-80.
    • (2003) Mutat Res , vol.531 , pp. 37-80
    • Bjelland, S.1    Seeberg, E.2
  • 53
    • 0026181844 scopus 로고
    • DNA repair and the role of chromatin structure
    • Smerdon MJ. DNA repair and the role of chromatin structure. Curr Opin Cell Biol 1991; 3:422-8.
    • (1991) Curr Opin Cell Biol , vol.3 , pp. 422-428
    • Smerdon, M.J.1
  • 54
    • 77952564842 scopus 로고    scopus 로고
    • Oxidative stress triggers the preferential assembly of base excision repair complexes on open chromatin regions
    • Amouroux R, Campalans A, Epe B, Radicella JP. Oxidative stress triggers the preferential assembly of base excision repair complexes on open chromatin regions. Nucleic Acids Res 2010; 38:2878-90.
    • (2010) Nucleic Acids Res , vol.38 , pp. 2878-2890
    • Amouroux, R.1    Campalans, A.2    Epe, B.3    Radicella, J.P.4
  • 55
    • 77952095382 scopus 로고    scopus 로고
    • Spatiotemporal characterization of ionizing radiation induced DNA damage foci and their relation to chromatin organization
    • Costes SV, Chiolo I, Pluth JM, Barcellos-Hoff MH, Jakob B. Spatiotemporal characterization of ionizing radiation induced DNA damage foci and their relation to chromatin organization. Mutat Res 2010; 704:78-87.
    • (2010) Mutat Res , vol.704 , pp. 78-87
    • Costes, S.V.1    Chiolo, I.2    Pluth, J.M.3    Barcellos-Hoff, M.H.4    Jakob, B.5
  • 56
    • 0030941116 scopus 로고    scopus 로고
    • Chromatin structure modulates DNA repair by photolyase in vivo
    • Suter B, Livingstone-Zatchej M, Thoma F. Chromatin structure modulates DNA repair by photolyase in vivo. EMBO J 1997; 16:2150-60.
    • (1997) EMBO J , vol.16 , pp. 2150-2160
    • Suter, B.1    Livingstone-Zatchej, M.2    Thoma, F.3
  • 57
    • 50849104569 scopus 로고    scopus 로고
    • Double strand breaks can initiate gene silencing and SIRT1-dependent onset of DNA methylation in an exogenous promoter CpG island
    • O'Hagan HM, Mohammad HP, Baylin SB. Double strand breaks can initiate gene silencing and SIRT1-dependent onset of DNA methylation in an exogenous promoter CpG island. PLoS Genet 2008; 4:1000155.
    • (2008) PLoS Genet , vol.4 , pp. 1000155
    • O'Hagan, H.M.1    Mohammad, H.P.2    Baylin, S.B.3
  • 58
    • 0023145290 scopus 로고
    • A line of non-tumorigenic mouse melanocytes, syngeneic with the B16 melanoma and requiring a tumour promoter for growth
    • Bennett DC, Cooper PJ, Hart IR. A line of non-tumorigenic mouse melanocytes, syngeneic with the B16 melanoma and requiring a tumour promoter for growth. Int J Cancer 1987; 39:414-8.
    • (1987) Int J Cancer , vol.39 , pp. 414-418
    • Bennett, D.C.1    Cooper, P.J.2    Hart, I.R.3
  • 59
    • 0036314920 scopus 로고    scopus 로고
    • Quantitative methylation analysis using methylation-sensitive single-nucleotide primer extension (Ms-SNuPE)
    • Gonzalgo ML, Jones PA. Quantitative methylation analysis using methylation-sensitive single-nucleotide primer extension (Ms-SNuPE). Methods 2002; 27:128-33.
    • (2002) Methods , vol.27 , pp. 128-133
    • Gonzalgo, M.L.1    Jones, P.A.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.