-
1
-
-
61849166005
-
The structure, regulation, and function of ZAP-70
-
Au-Yeung BB, Deindl S, Hsu LY, Palacios EH, Levin SE, et al. (2009) The structure, regulation, and function of ZAP-70. Immunol Rev 228: 41-57.
-
(2009)
Immunol Rev
, vol.228
, pp. 41-57
-
-
Au-Yeung, B.B.1
Deindl, S.2
Hsu, L.Y.3
Palacios, E.H.4
Levin, S.E.5
-
2
-
-
8444247821
-
The SLP-76 family of adapter proteins
-
Wu JN, Koretzky GA, (2004) The SLP-76 family of adapter proteins. Semin Immunol 16: 379-393.
-
(2004)
Semin Immunol
, vol.16
, pp. 379-393
-
-
Wu, J.N.1
Koretzky, G.A.2
-
3
-
-
70350376377
-
Regulation of lymphocyte development and activation by the LAT family of adapter proteins
-
Fuller DM, Zhang W, (2009) Regulation of lymphocyte development and activation by the LAT family of adapter proteins. Immunol Rev 232: 72-83.
-
(2009)
Immunol Rev
, vol.232
, pp. 72-83
-
-
Fuller, D.M.1
Zhang, W.2
-
4
-
-
34548433014
-
Keeping the (kinase) party going: SLP-76 and ITK dance to the beat
-
Qi Q, August A, (2007) Keeping the (kinase) party going: SLP-76 and ITK dance to the beat. Sci STKE pp. pe39.
-
(2007)
Sci STKE
-
-
Qi, Q.1
August, A.2
-
5
-
-
27444445613
-
c-Cbl and Cbl-b ubiquitin ligases: substrate diversity and the negative regulation of signalling responses
-
Thien CB, Langdon WY, (2005) c-Cbl and Cbl-b ubiquitin ligases: substrate diversity and the negative regulation of signalling responses. Biochem J 391: 153-166.
-
(2005)
Biochem J
, vol.391
, pp. 153-166
-
-
Thien, C.B.1
Langdon, W.Y.2
-
6
-
-
42349108970
-
A tale of two Cbls: interplay of c-Cbl and Cbl-b in epidermal growth factor receptor downregulation
-
Pennock S, Wang Z, (2008) A tale of two Cbls: interplay of c-Cbl and Cbl-b in epidermal growth factor receptor downregulation. Mol Cell Biol 28: 3020-3037.
-
(2008)
Mol Cell Biol
, vol.28
, pp. 3020-3037
-
-
Pennock, S.1
Wang, Z.2
-
7
-
-
0037450822
-
A mouse with a loss-of-function mutation in the c-Cbl TKB domain shows perturbed thymocyte signaling without enhancing the activity of the ZAP-70 tyrosine kinase
-
Thien CB, Scaife RM, Papadimitriou JM, Murphy MA, Bowtell DD, et al. (2003) A mouse with a loss-of-function mutation in the c-Cbl TKB domain shows perturbed thymocyte signaling without enhancing the activity of the ZAP-70 tyrosine kinase. J Exp Med 197: 503-513.
-
(2003)
J Exp Med
, vol.197
, pp. 503-513
-
-
Thien, C.B.1
Scaife, R.M.2
Papadimitriou, J.M.3
Murphy, M.A.4
Bowtell, D.D.5
-
8
-
-
0032438114
-
Altered thymic positive selection and intracellular signals in Cbl-deficient mice
-
Naramura M, Kole HK, Hu RJ, Gu H, (1998) Altered thymic positive selection and intracellular signals in Cbl-deficient mice. Proc Natl Acad Sci U S A 95: 15547-15552.
-
(1998)
Proc Natl Acad Sci U S A
, vol.95
, pp. 15547-15552
-
-
Naramura, M.1
Kole, H.K.2
Hu, R.J.3
Gu, H.4
-
9
-
-
0033564933
-
Perturbed regulation of ZAP-70 and sustained tyrosine phosphorylation of LAT and SLP-76 in c-Cbl-deficient thymocytes
-
Thien CB, Bowtell DD, Langdon WY, (1999) Perturbed regulation of ZAP-70 and sustained tyrosine phosphorylation of LAT and SLP-76 in c-Cbl-deficient thymocytes. J Immunol 162: 7133-7139.
-
(1999)
J Immunol
, vol.162
, pp. 7133-7139
-
-
Thien, C.B.1
Bowtell, D.D.2
Langdon, W.Y.3
-
10
-
-
29244448977
-
Src-like adaptor protein regulates TCR expression on thymocytes by linking the ubiquitin ligase c-Cbl to the TCR complex
-
Myers MD, Sosinowski T, Dragone LL, White C, Band H, et al. (2006) Src-like adaptor protein regulates TCR expression on thymocytes by linking the ubiquitin ligase c-Cbl to the TCR complex. Nat Immunol 7: 57-66.
-
(2006)
Nat Immunol
, vol.7
, pp. 57-66
-
-
Myers, M.D.1
Sosinowski, T.2
Dragone, L.L.3
White, C.4
Band, H.5
-
11
-
-
0032211059
-
Differential requirements for ZAP-70 in TCR signaling and T cell development
-
Kadlecek TA, van Oers NS, Lefrancois L, Olson S, Finlay D, et al. (1998) Differential requirements for ZAP-70 in TCR signaling and T cell development. J Immunol 161: 4688-4694.
-
(1998)
J Immunol
, vol.161
, pp. 4688-4694
-
-
Kadlecek, T.A.1
van Oers, N.S.2
Lefrancois, L.3
Olson, S.4
Finlay, D.5
-
12
-
-
3142676432
-
Inactivation of c-Cbl reverses neonatal lethality and T cell developmental arrest of SLP-76-deficient mice
-
Chiang YJ, Sommers CL, Jordan MS, Gu H, Samelson LE, et al. (2004) Inactivation of c-Cbl reverses neonatal lethality and T cell developmental arrest of SLP-76-deficient mice. J Exp Med 200: 25-34.
-
(2004)
J Exp Med
, vol.200
, pp. 25-34
-
-
Chiang, Y.J.1
Sommers, C.L.2
Jordan, M.S.3
Gu, H.4
Samelson, L.E.5
-
13
-
-
0032540906
-
Requirement for the leukocyte-specific adapter protein SLP-76 for normal T cell development
-
Clements JL, Yang B, Ross-Barta SE, Eliason SL, Hrstka RF, et al. (1998) Requirement for the leukocyte-specific adapter protein SLP-76 for normal T cell development. Science 281: 416-419.
-
(1998)
Science
, vol.281
, pp. 416-419
-
-
Clements, J.L.1
Yang, B.2
Ross-Barta, S.E.3
Eliason, S.L.4
Hrstka, R.F.5
-
14
-
-
0032563256
-
Impaired viability and profound block in thymocyte development in mice lacking the adaptor protein SLP-76
-
Pivniouk V, Tsitsikov E, Swinton P, Rathbun G, Alt FW, et al. (1998) Impaired viability and profound block in thymocyte development in mice lacking the adaptor protein SLP-76. Cell 94: 229-238.
-
(1998)
Cell
, vol.94
, pp. 229-238
-
-
Pivniouk, V.1
Tsitsikov, E.2
Swinton, P.3
Rathbun, G.4
Alt, F.W.5
-
15
-
-
0033103833
-
Essential role of LAT in T cell development
-
Zhang W, Sommers CL, Burshtyn DN, Stebbins CC, DeJarnette JB, et al. (1999) Essential role of LAT in T cell development. Immunity 10: 323-332.
-
(1999)
Immunity
, vol.10
, pp. 323-332
-
-
Zhang, W.1
Sommers, C.L.2
Burshtyn, D.N.3
Stebbins, C.C.4
DeJarnette, J.B.5
-
16
-
-
63249123347
-
Cbl enforces an SLP76-dependent signaling pathway for T cell differentiation
-
Chiang YJ, Jordan MS, Horai R, Schwartzberg PL, Koretzky GA, et al. (2009) Cbl enforces an SLP76-dependent signaling pathway for T cell differentiation. J Biol Chem 284: 4429-4438.
-
(2009)
J Biol Chem
, vol.284
, pp. 4429-4438
-
-
Chiang, Y.J.1
Jordan, M.S.2
Horai, R.3
Schwartzberg, P.L.4
Koretzky, G.A.5
-
17
-
-
2442444247
-
Vav1 transduces T cell receptor signals to the activation of the Ras/ERK pathway via LAT, Sos, and RasGRP1
-
Reynolds LF, de Bettignies C, Norton T, Beeser A, Chernoff J, et al. (2004) Vav1 transduces T cell receptor signals to the activation of the Ras/ERK pathway via LAT, Sos, and RasGRP1. J Biol Chem 279: 18239-18246.
-
(2004)
J Biol Chem
, vol.279
, pp. 18239-18246
-
-
Reynolds, L.F.1
de Bettignies, C.2
Norton, T.3
Beeser, A.4
Chernoff, J.5
-
18
-
-
0037029653
-
Vav1 transduces T cell receptor signals to the activation of phospholipase C-gamma1 via phosphoinositide 3-kinase-dependent and -independent pathways
-
Reynolds LF, Smyth LA, Norton T, Freshney N, Downward J, et al. (2002) Vav1 transduces T cell receptor signals to the activation of phospholipase C-gamma1 via phosphoinositide 3-kinase-dependent and-independent pathways. J Exp Med 195: 1103-1114.
-
(2002)
J Exp Med
, vol.195
, pp. 1103-1114
-
-
Reynolds, L.F.1
Smyth, L.A.2
Norton, T.3
Freshney, N.4
Downward, J.5
-
19
-
-
0030719389
-
A requirement for the Rho-family GTP exchange factor Vav in positive and negative selection of thymocytes
-
Turner M, Mee PJ, Walters AE, Quinn ME, Mellor AL, et al. (1997) A requirement for the Rho-family GTP exchange factor Vav in positive and negative selection of thymocytes. Immunity 7: 451-460.
-
(1997)
Immunity
, vol.7
, pp. 451-460
-
-
Turner, M.1
Mee, P.J.2
Walters, A.E.3
Quinn, M.E.4
Mellor, A.L.5
-
20
-
-
17044381787
-
Fetal expression of Fas ligand is necessary and sufficient for induction of CD8 T cell tolerance to the fetal antigen H-Y during pregnancy
-
Vacchio MS, Hodes RJ, (2005) Fetal expression of Fas ligand is necessary and sufficient for induction of CD8 T cell tolerance to the fetal antigen H-Y during pregnancy. J Immunol 174: 4657-4661.
-
(2005)
J Immunol
, vol.174
, pp. 4657-4661
-
-
Vacchio, M.S.1
Hodes, R.J.2
-
21
-
-
22944479958
-
Src-like adaptor protein down-regulates T cell receptor (TCR)-CD3 expression by targeting TCRzeta for degradation
-
Myers MD, Dragone LL, Weiss A, (2005) Src-like adaptor protein down-regulates T cell receptor (TCR)-CD3 expression by targeting TCRzeta for degradation. J Cell Biol 170: 285-294.
-
(2005)
J Cell Biol
, vol.170
, pp. 285-294
-
-
Myers, M.D.1
Dragone, L.L.2
Weiss, A.3
-
22
-
-
18244408051
-
Differential requirement for SLP-76 domains in T cell development and function
-
Myung PS, Derimanov GS, Jordan MS, Punt JA, Liu QH, et al. (2001) Differential requirement for SLP-76 domains in T cell development and function. Immunity 15: 1011-1026.
-
(2001)
Immunity
, vol.15
, pp. 1011-1026
-
-
Myung, P.S.1
Derimanov, G.S.2
Jordan, M.S.3
Punt, J.A.4
Liu, Q.H.5
-
23
-
-
0141866846
-
Cbl-mediated ubiquitinylation and negative regulation of Vav
-
Miura-Shimura Y, Duan L, Rao NL, Reddi AL, Shimura H, et al. (2003) Cbl-mediated ubiquitinylation and negative regulation of Vav. J Biol Chem 278: 38495-38504.
-
(2003)
J Biol Chem
, vol.278
, pp. 38495-38504
-
-
Miura-Shimura, Y.1
Duan, L.2
Rao, N.L.3
Reddi, A.L.4
Shimura, H.5
-
24
-
-
0030887137
-
Direct T cell activation by chimeric single chain Fv-Syk promotes Syk-Cbl association and Cbl phosphorylation
-
Fitzer-Attas CJ, Schindler DG, Waks T, Eshhar Z, (1997) Direct T cell activation by chimeric single chain Fv-Syk promotes Syk-Cbl association and Cbl phosphorylation. J Biol Chem 272: 8551-8557.
-
(1997)
J Biol Chem
, vol.272
, pp. 8551-8557
-
-
Fitzer-Attas, C.J.1
Schindler, D.G.2
Waks, T.3
Eshhar, Z.4
-
25
-
-
0029664998
-
Interactions of Cbl with two adapter proteins, Grb2 and Crk, upon T cell activation
-
Buday L, Khwaja A, Sipeki S, Farago A, Downward J, (1996) Interactions of Cbl with two adapter proteins, Grb2 and Crk, upon T cell activation. J Biol Chem 271: 6159-6163.
-
(1996)
J Biol Chem
, vol.271
, pp. 6159-6163
-
-
Buday, L.1
Khwaja, A.2
Sipeki, S.3
Farago, A.4
Downward, J.5
-
26
-
-
0029671073
-
p120cbl is a major substrate of tyrosine phosphorylation upon B cell antigen receptor stimulation and interacts in vivo with Fyn and Syk tyrosine kinases, Grb2 and Shc adaptors, and the p85 subunit of phosphatidylinositol 3-kinase
-
Panchamoorthy G, Fukazawa T, Miyake S, Soltoff S, Reedquist K, et al. (1996) p120cbl is a major substrate of tyrosine phosphorylation upon B cell antigen receptor stimulation and interacts in vivo with Fyn and Syk tyrosine kinases, Grb2 and Shc adaptors, and the p85 subunit of phosphatidylinositol 3-kinase. J Biol Chem 271: 3187-3194.
-
(1996)
J Biol Chem
, vol.271
, pp. 3187-3194
-
-
Panchamoorthy, G.1
Fukazawa, T.2
Miyake, S.3
Soltoff, S.4
Reedquist, K.5
-
27
-
-
10744222965
-
Vav1/2/3-null mice define an essential role for Vav family proteins in lymphocyte development and activation but a differential requirement in MAPK signaling in T and B cells
-
Fujikawa K, Miletic AV, Alt FW, Faccio R, Brown T, et al. (2003) Vav1/2/3-null mice define an essential role for Vav family proteins in lymphocyte development and activation but a differential requirement in MAPK signaling in T and B cells. J Exp Med 198: 1595-1608.
-
(2003)
J Exp Med
, vol.198
, pp. 1595-1608
-
-
Fujikawa, K.1
Miletic, A.V.2
Alt, F.W.3
Faccio, R.4
Brown, T.5
-
28
-
-
0036911112
-
c-Cbl and Cbl-b regulate T cell responsiveness by promoting ligand-induced TCR down-modulation
-
Naramura M, Jang IK, Kole H, Huang F, Haines D, et al. (2002) c-Cbl and Cbl-b regulate T cell responsiveness by promoting ligand-induced TCR down-modulation. Nat Immunol 3: 1192-1199.
-
(2002)
Nat Immunol
, vol.3
, pp. 1192-1199
-
-
Naramura, M.1
Jang, I.K.2
Kole, H.3
Huang, F.4
Haines, D.5
-
29
-
-
0033680925
-
Cbl-b is a negative regulator of receptor clustering and raft aggregation in T cells
-
Krawczyk C, Bachmaier K, Sasaki T, Jones RG, Snapper SB, et al. (2000) Cbl-b is a negative regulator of receptor clustering and raft aggregation in T cells. Immunity 13: 463-473.
-
(2000)
Immunity
, vol.13
, pp. 463-473
-
-
Krawczyk, C.1
Bachmaier, K.2
Sasaki, T.3
Jones, R.G.4
Snapper, S.B.5
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