IFNγ triggers a LIGHT-dependent selective death of motoneurons contributing to the non-cell-autonomous effects of mutant SOD1

Cell Death and Differentiation

Volumn 18, Issue 5, 2011, Pages 754-768

  Aebischer, J ^a,b   Cassina, P ^c   Otsmane, B ^a,b   Moumen, A ^a,b   Seilhean, D ^d   Meininger, V ^e   Barbeito, L ^c   Pettmann, B ^a,b   Raoul, C ^a,b  

^a Turing Center for Living Systems CENTURI Aix Marseille University   (France)

^b AIX MARSEILLE UNIVERSITY   (France)

^c INSTITUTO DE INVESTIGACIONES BIOLÓGICAS CLEMENTE ESTABLE   (Uruguay)

^d SORBONNE UNIVERSITÉ   (France)

^e PITIÉ SALPÊTRIÈRE HOSPITAL   (France)

Author keywords

amyotrophic lateral sclerosis; astrocytes; interferon g; LIGHT; motoneurons

Indexed keywords

COPPER ZINC SUPEROXIDE DISMUTASE; GAMMA INTERFERON; HERPESVIRUS ENTRY MEDIATOR LIGAND; LYMPHOTOXIN BETA RECEPTOR;

AMYOTROPHIC LATERAL SCLEROSIS; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; ASTROCYTE; CELL INTERACTION; CELL LOSS; CONTROLLED STUDY; DISEASE COURSE; EMBRYO; FEMALE; GENE EXPRESSION; GENE MUTATION; IN VIVO STUDY; LIFESPAN; LIGHT; MALE; MOTONEURON; MOUSE; NERVE CELL NECROSIS; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT; SIGNAL TRANSDUCTION;

AMYOTROPHIC LATERAL SCLEROSIS; ANIMALS; ANTIGENS, CD95; ASTROCYTES; CASPASES; CELL DEATH; CELL SURVIVAL; CELLS, CULTURED; ENZYME ACTIVATION; GENE DELETION; HUMANS; INTERFERON-GAMMA; LYMPHOTOXIN BETA RECEPTOR; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; MOTOR NEURONS; MUTATION, MISSENSE; RATS; RATS, SPRAGUE-DAWLEY; SIGNAL TRANSDUCTION; SUPEROXIDE DISMUTASE; TUMOR NECROSIS FACTOR LIGAND SUPERFAMILY MEMBER 14;

MUS;

EID: 79954425316     PISSN: 13509047     EISSN: 14765403     Source Type: Journal    
DOI: 10.1038/cdd.2010.143     Document Type: Article

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