Inhibition of the mitochondrial permeability transition by the nonimmunosuppressive cyclosporin derivative NIM811

Molecular Pharmacology

Volumn 62, Issue 1, 2002, Pages 22-29

  Waldmeier, Peter C ^a   Feldtrauer, Jean Jacques ^a   Qian, Ting ^a   Lemasters, John J ^a,b  

^a NOVARTIS PHARMA AG   (Switzerland)

^b UNIVERSITY OF NORTH CAROLINA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

1,2,3,6 TETRAHYDRO 1 METHYL 4 PHENYLPYRIDINE; CALCINEURIN; CALCIUM; CYCLOPHILIN A; CYCLOSPORIN A; CYCLOSPORIN DERIVATIVE; N METHYL 4 ISOLEUCINE CYCLOSPORIN; N METHYL 4 VALINE CYCLOSPORIN; NIM 811; PHOSPHATE; PKF 220384; ROTENONE; TERT BUTYL HYDROPEROXIDE; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG;

ANIMAL CELL; APOPTOSIS; ARTICLE; CELL MEMBRANE DEPOLARIZATION; CELL MEMBRANE PERMEABILITY; CELL MEMBRANE POTENTIAL; CELL PROTECTION; CONFOCAL MICROSCOPY; CONTROLLED STUDY; CYTOTOXICITY; LIVER CELL; MICROTITER PLATE ASSAY; MITOCHONDRION; MITOCHONDRION SWELLING; NONHUMAN; PRIORITY JOURNAL; RAT;

1-METHYL-4-PHENYLPYRIDINIUM; ANIMALS; APOPTOSIS; CALCIUM; CALIBRATION; CYCLOSPORINE; DRUG INTERACTIONS; ION CHANNELS; MALE; MEMBRANE POTENTIALS; MITOCHONDRIA; MITOCHONDRIAL MEMBRANE TRANSPORT PROTEINS; MITOCHONDRIAL SWELLING; PHENAZINES; PROTECTIVE AGENTS; RATS; RATS, SPRAGUE-DAWLEY; ROTENONE; TUMOR NECROSIS FACTOR-ALPHA; UNCOUPLING AGENTS;

EID: 0036088518     PISSN: 0026895X     EISSN: None     Source Type: Journal    
DOI: 10.1124/mol.62.1.22     Document Type: Article

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