-
1
-
-
33644942482
-
Genetic improvement of processes yielding microbial products
-
Adrio, J.L. and Demain, A.L. (2006) Genetic improvement of processes yielding microbial products. FEMS Microbiol Rev 30, 187-214.
-
(2006)
FEMS Microbiol Rev
, vol.30
, pp. 187-214
-
-
Adrio, J.L.1
Demain, A.L.2
-
2
-
-
0031855459
-
When blind is better: protein design by evolution
-
Arnold, F.H. (1998) When blind is better: protein design by evolution. Nat Biotechnol 16, 617-618.
-
(1998)
Nat Biotechnol
, vol.16
, pp. 617-618
-
-
Arnold, F.H.1
-
3
-
-
0035843136
-
Combinatorial and computational challenges for biocatalyst design
-
Arnold, F.H. (2001) Combinatorial and computational challenges for biocatalyst design. Nature 409, 253-257.
-
(2001)
Nature
, vol.409
, pp. 253-257
-
-
Arnold, F.H.1
-
4
-
-
0033582799
-
Mycoepoxydiene represents a novel class of fungal metabolites
-
Cai, P., McPhail, A.T., Krainer, E., Krainer, E., Katz, B., Pearce, C., Boros, C., Caceres, B. et al. (1999) Mycoepoxydiene represents a novel class of fungal metabolites. Tetrahedron Lett 40, 1479-1482.
-
(1999)
Tetrahedron Lett
, vol.40
, pp. 1479-1482
-
-
Cai, P.1
McPhail, A.T.2
Krainer, E.3
Krainer, E.4
Katz, B.5
Pearce, C.6
Boros, C.7
Caceres, B.8
-
5
-
-
0028359789
-
Two new cytotoxic cytochalasins from Xylaria obovata
-
Dagne, E., Gunatilaka, L., Asmellash, S., Abate, D., Kingston, D., Hofmann, G.A. and Johnson, R. (1994) Two new cytotoxic cytochalasins from Xylaria obovata. Tetrahedron 50, 5615-5620.
-
(1994)
Tetrahedron
, vol.50
, pp. 5615-5620
-
-
Dagne, E.1
Gunatilaka, L.2
Asmellash, S.3
Abate, D.4
Kingston, D.5
Hofmann, G.A.6
Johnson, R.7
-
6
-
-
3543063259
-
Genome shuffling improves degradation of the anthropogenic pesticide pentachlorophenol by Sphingobium chlorophenolicum ATCC 39723
-
Dai, M. and Copley, S.D. (2004) Genome shuffling improves degradation of the anthropogenic pesticide pentachlorophenol by Sphingobium chlorophenolicum ATCC 39723. Appl Environ Microbiol 70, 2391-2397.
-
(2004)
Appl Environ Microbiol
, vol.70
, pp. 2391-2397
-
-
Dai, M.1
Copley, S.D.2
-
7
-
-
34547654448
-
Mutation and a high-throughput screening method for improving the production of Epothilones of Sorangium
-
Gong, G.L., Sun, X., Liu, X.L., Hu, W., Cao, W., Liu, H., Liu, W. and Li, Y.Z. (2007) Mutation and a high-throughput screening method for improving the production of Epothilones of Sorangium. J Ind Microbiol Biotechnol 34, 1476-5535.
-
(2007)
J Ind Microbiol Biotechnol
, vol.34
, pp. 1476-5535
-
-
Gong, G.L.1
Sun, X.2
Liu, X.L.3
Hu, W.4
Cao, W.5
Liu, H.6
Liu, W.7
Li, Y.Z.8
-
8
-
-
0038461995
-
Drugs from the deep: marine natural products as drug candidates
-
Haefner, B. (2003) Drugs from the deep: marine natural products as drug candidates. Drug Discov Today 8, 536-544.
-
(2003)
Drug Discov Today
, vol.8
, pp. 536-544
-
-
Haefner, B.1
-
9
-
-
0030882605
-
Preparation of mitochondrial DNA from fungal protoplasts
-
Hamari, Z., Pfeiffer, I., Kevei, F. and Ferenczy, L. (1997) Preparation of mitochondrial DNA from fungal protoplasts. J Microbiol Methods 30, 165-166.
-
(1997)
J Microbiol Methods
, vol.30
, pp. 165-166
-
-
Hamari, Z.1
Pfeiffer, I.2
Kevei, F.3
Ferenczy, L.4
-
10
-
-
0030272727
-
Metabolic engineering of polyketide biosynthesis
-
Hershberger, C.L. (1996) Metabolic engineering of polyketide biosynthesis. Curr Opin Biotechnol 7, 560-562.
-
(1996)
Curr Opin Biotechnol
, vol.7
, pp. 560-562
-
-
Hershberger, C.L.1
-
11
-
-
0023948846
-
Use of protoplasts in the improvement of filamentous fungi I. Mutagenization of protoplasts of Oudemansiella mucida
-
Homolka, L. and Pilát, P. (1988) Use of protoplasts in the improvement of filamentous fungi I. Mutagenization of protoplasts of Oudemansiella mucida. Appl Microbiol Biotechnol 28, 166-169.
-
(1988)
Appl Microbiol Biotechnol
, vol.28
, pp. 166-169
-
-
Homolka, L.1
Pilát, P.2
-
12
-
-
0021844476
-
Production of 'hybrid' antibiotics by genetic engineering
-
Hopwood, D.A., Malpartida, F., Kieser, H.M., Ikeda, H., Duncan, J., Fujii, I., Rudd, B.A., Floss, H.G. et al. (1985) Production of 'hybrid' antibiotics by genetic engineering. Nature 314, 642-644.
-
(1985)
Nature
, vol.314
, pp. 642-644
-
-
Hopwood, D.A.1
Malpartida, F.2
Kieser, H.M.3
Ikeda, H.4
Duncan, J.5
Fujii, I.6
Rudd, B.A.7
Floss, H.G.8
-
13
-
-
0032082090
-
Combinatorial biosynthesis for new drug discovery
-
Hutchinson, C.R. (1998) Combinatorial biosynthesis for new drug discovery. Curr Opin Microbiol 1, 319-329.
-
(1998)
Curr Opin Microbiol
, vol.1
, pp. 319-329
-
-
Hutchinson, C.R.1
-
14
-
-
22144459351
-
Screening, mutagenesis and protoplast fusion of Aspergillus niger for the enhancement of extracellular glucose oxidase production
-
Khattab, A.A. and Bazaraa, W.A. (2005) Screening, mutagenesis and protoplast fusion of Aspergillus niger for the enhancement of extracellular glucose oxidase production. J Ind Microbiol Biotechnol 32, 289-294.
-
(2005)
J Ind Microbiol Biotechnol
, vol.32
, pp. 289-294
-
-
Khattab, A.A.1
Bazaraa, W.A.2
-
15
-
-
0346328227
-
Metabolic engineering for drug discovery and development
-
Khosla, C. and Keasling, J.D. (2003) Metabolic engineering for drug discovery and development. Nat Rev Drug Discov 2, 1019-1025.
-
(2003)
Nat Rev Drug Discov
, vol.2
, pp. 1019-1025
-
-
Khosla, C.1
Keasling, J.D.2
-
16
-
-
0031543435
-
Directed evolution of enzyme catalysts
-
Kuchner, O. and Arnold, F.H. (1997) Directed evolution of enzyme catalysts. Trends Biotechnol 15, 523-530.
-
(1997)
Trends Biotechnol
, vol.15
, pp. 523-530
-
-
Kuchner, O.1
Arnold, F.H.2
-
17
-
-
0033962763
-
A rapid technique for screening of lovastatin-producing strains of Aspergillus terreus by agar plug and Neurospora crassa bioassay
-
Kumar, M.S., Kumar, P.M., Sarnaik, H.M. and Sadhukhan, A.K. (2000) A rapid technique for screening of lovastatin-producing strains of Aspergillus terreus by agar plug and Neurospora crassa bioassay. J Microbiol Meth 40, 99-104.
-
(2000)
J Microbiol Meth
, vol.40
, pp. 99-104
-
-
Kumar, M.S.1
Kumar, P.M.2
Sarnaik, H.M.3
Sadhukhan, A.K.4
-
18
-
-
24944552436
-
Cytotoxic and antimicrobial metabolites from marine lignicolous fungi, Diaporthe sp
-
Lin, X., Huang, Y.J., Fang, M.J., Wang, J.F., Zheng, Z.H. and Su, W.J. (2005) Cytotoxic and antimicrobial metabolites from marine lignicolous fungi, Diaporthe sp. FEMS Microbiol Lett 251, 53-58.
-
(2005)
FEMS Microbiol Lett
, vol.251
, pp. 53-58
-
-
Lin, X.1
Huang, Y.J.2
Fang, M.J.3
Wang, J.F.4
Zheng, Z.H.5
Su, W.J.6
-
19
-
-
0021061819
-
Rapid colourimetric assay for cellular growth and survival: application to proliferation and cytotoxicity assays
-
Mosmann, T. (1983) Rapid colourimetric assay for cellular growth and survival: application to proliferation and cytotoxicity assays. J Immunol Methods 65, 55-63.
-
(1983)
J Immunol Methods
, vol.65
, pp. 55-63
-
-
Mosmann, T.1
-
20
-
-
0033775264
-
Molecular breeding: the natural approach to protein design
-
Ness, J.E., Del Cardayre, S.B., Minshull, J. and Stemmer, W.P. (2000) Molecular breeding: the natural approach to protein design. Adv Protein Chem 55, 261-292.
-
(2000)
Adv Protein Chem
, vol.55
, pp. 261-292
-
-
Ness, J.E.1
Del Cardayre, S.B.2
Minshull, J.3
Stemmer, W.P.4
-
21
-
-
0030722164
-
Applications of DNA shuffling to pharmaceuticals and vaccines
-
Patten, P.A., Howard, R.J. and Stemmer, W.P. (1997) Applications of DNA shuffling to pharmaceuticals and vaccines. Curr Opin Biotechnol 8, 724-733.
-
(1997)
Curr Opin Biotechnol
, vol.8
, pp. 724-733
-
-
Patten, P.A.1
Howard, R.J.2
Stemmer, W.P.3
-
22
-
-
85058203988
-
Fungi without coats-protoplasts as tools for mycological research
-
Peberdy, J. (1989) Fungi without coats-protoplasts as tools for mycological research. Mycol Res 93, 1-20.
-
(1989)
Mycol Res
, vol.93
, pp. 1-20
-
-
Peberdy, J.1
-
23
-
-
36048955511
-
Cytotoxic mycoepoxydiene derivatives from an endophytic fungus Phomopsis sp. isolated from Hydnocarpus anthelminthicus
-
Prachya, S., Wiyakrutta, S., Sriubolmas, N., Ngamrojanavanich, N., Mahidol, C., Ruchirawat, S. and Kittakoop, P. (2007) Cytotoxic mycoepoxydiene derivatives from an endophytic fungus Phomopsis sp. isolated from Hydnocarpus anthelminthicus. Planta Med 73, 1418-1420.
-
(2007)
Planta Med
, vol.73
, pp. 1418-1420
-
-
Prachya, S.1
Wiyakrutta, S.2
Sriubolmas, N.3
Ngamrojanavanich, N.4
Mahidol, C.5
Ruchirawat, S.6
Kittakoop, P.7
-
24
-
-
0038544618
-
The enzymology of combinatorial biosynthesis
-
Reeves, C.D. (2003) The enzymology of combinatorial biosynthesis. Crit Rev Biotechnol 23, 95-147.
-
(2003)
Crit Rev Biotechnol
, vol.23
, pp. 95-147
-
-
Reeves, C.D.1
-
25
-
-
34848923305
-
Marine natural products of fungal origin
-
Saleem, M., Ali, M.S., Hussain, S., Jabbar, A., Ashraf, M. and Lee, Y.S. (2007) Marine natural products of fungal origin. Nat Prod Rep 24, 1142-1152.
-
(2007)
Nat Prod Rep
, vol.24
, pp. 1142-1152
-
-
Saleem, M.1
Ali, M.S.2
Hussain, S.3
Jabbar, A.4
Ashraf, M.5
Lee, Y.S.6
-
26
-
-
36949009858
-
Developments in directed evolution for improving enzyme functions
-
Sen, S., Venkata Dasu, V. and Mandal, B. (2007) Developments in directed evolution for improving enzyme functions. Appl Biochem Biotechnol 143, 212-223.
-
(2007)
Appl Biochem Biotechnol
, vol.143
, pp. 212-223
-
-
Sen, S.1
Venkata Dasu, V.2
Mandal, B.3
-
27
-
-
85164287251
-
-
Method for preparing deacetyl mycoepoxydiene from metabolite of Phomosis A-1-2-3 and its application in antitumour drugs and other bioactive precursor. China.
-
Shen, Y.M., Yang, L.S., Huang, Y.J., Zheng, Z.H., Song, S.Y. and Su, W.J. (2007) Method for preparing deacetyl mycoepoxydiene from metabolite of Phomosis A-1-2-3 and its application in antitumour drugs and other bioactive precursor. China.
-
(2007)
-
-
Shen, Y.M.1
Yang, L.S.2
Huang, Y.J.3
Zheng, Z.H.4
Song, S.Y.5
Su, W.J.6
-
28
-
-
0031442821
-
Creating novel enzymes by applied molecular evolution
-
Skandalis, A., Encell, L.P. and Loeb, L.A. (1997) Creating novel enzymes by applied molecular evolution. Chem Biol 4, 889-898.
-
(1997)
Chem Biol
, vol.4
, pp. 889-898
-
-
Skandalis, A.1
Encell, L.P.2
Loeb, L.A.3
-
29
-
-
0028050350
-
Rapid evolution of a protein in vitro by DNA shuffling
-
Stemmer, W.P. (1994) Rapid evolution of a protein in vitro by DNA shuffling. Nature 370, 389-391.
-
(1994)
Nature
, vol.370
, pp. 389-391
-
-
Stemmer, W.P.1
-
30
-
-
0042190058
-
Total synthesis of (+/-)-mycoepoxydiene, a novel fungal metabolite having an oxygen-bridged cyclooctadiene skeleton
-
Takao, K., Watanabe, G., Yasui, H. and Tadano, K. (2002) Total synthesis of (+/-)-mycoepoxydiene, a novel fungal metabolite having an oxygen-bridged cyclooctadiene skeleton. Org Lett 4, 2941-2943.
-
(2002)
Org Lett
, vol.4
, pp. 2941-2943
-
-
Takao, K.1
Watanabe, G.2
Yasui, H.3
Tadano, K.4
-
31
-
-
10044263386
-
Asymmetric total syntheses of (+)-mycoepoxydiene and related natural product (-)-1893A: application of one-pot ring-opening/cross/ring-closing metathesis to construct their 9-oxabicyclo[4.2.1]nona-2,4-diene skeleton
-
Takao, K., Yasui, H., Yamamoto, S., Sasaki, D., Kawasaki, S., Watanabe, G. and Tadano, K. (2004) Asymmetric total syntheses of (+)-mycoepoxydiene and related natural product (-)-1893A: application of one-pot ring-opening/cross/ring-closing metathesis to construct their 9-oxabicyclo[4.2.1]nona-2, 4-diene skeleton. J Org Chem 69, 8789-8795.
-
(2004)
J Org Chem
, vol.69
, pp. 8789-8795
-
-
Takao, K.1
Yasui, H.2
Yamamoto, S.3
Sasaki, D.4
Kawasaki, S.5
Watanabe, G.6
Tadano, K.7
-
32
-
-
0033928844
-
Directed evolution: the 'rational' basis for 'irrational' design
-
Tobin, M.B., Gustafsson, C. and Huisman, G.W. (2000) Directed evolution: the 'rational' basis for 'irrational' design. Curr Opin Struct Biol 10, 421-427.
-
(2000)
Curr Opin Struct Biol
, vol.10
, pp. 421-427
-
-
Tobin, M.B.1
Gustafsson, C.2
Huisman, G.W.3
-
33
-
-
0033829893
-
A sensitive standardised micro-gel well diffusion assay for the determination of antimicrobial activity
-
du Toit, E.A. and Rautenbach, M. (2000) A sensitive standardised micro-gel well diffusion assay for the determination of antimicrobial activity. J Microbiol Methods 42, 159-165.
-
(2000)
J Microbiol Methods
, vol.42
, pp. 159-165
-
-
du Toit, E.A.1
Rautenbach, M.2
-
34
-
-
48949117165
-
High-throughput enzymology and combinatorial mutagenesis for mining cytochrome P450 functions
-
Urban, P., Truan, G. and Pompon, D. (2008) High-throughput enzymology and combinatorial mutagenesis for mining cytochrome P450 functions. Expert Opin Drug Metab Toxicol 4, 733-747.
-
(2008)
Expert Opin Drug Metab Toxicol
, vol.4
, pp. 733-747
-
-
Urban, P.1
Truan, G.2
Pompon, D.3
-
35
-
-
24044550315
-
A high-throughput method for screening of rapamycin-producing strains of Streptomyces hygroscopicus by cultivation in 96-well microtiter plates
-
Xu, Z.N., Shen, W.H., Chen, X.Y., Lin, J.P. and Cen, P.L. (2005) A high-throughput method for screening of rapamycin-producing strains of Streptomyces hygroscopicus by cultivation in 96-well microtiter plates. Biotechnol Lett 27, 1135-1140.
-
(2005)
Biotechnol Lett
, vol.27
, pp. 1135-1140
-
-
Xu, Z.N.1
Shen, W.H.2
Chen, X.Y.3
Lin, J.P.4
Cen, P.L.5
-
36
-
-
67649314113
-
Cytotoxic cytochalasin metabolites of endophytic Endothia gyrosa
-
Xu, S., Ge, H.M., Song, Y.C., Shen, Y., Ding, H. and Tan, R.X. (2009) Cytotoxic cytochalasin metabolites of endophytic Endothia gyrosa. Chem Biodivers 6, 739-745.
-
(2009)
Chem Biodivers
, vol.6
, pp. 739-745
-
-
Xu, S.1
Ge, H.M.2
Song, Y.C.3
Shen, Y.4
Ding, H.5
Tan, R.X.6
-
37
-
-
85164280677
-
Genome shuffling leads to rapid phenotypic improvement in bacteria
-
Zhang, Y.X., Perry, K., Vinci, V.A., Powell, K., Stemmer, W.P. and del Cardayré, S.B. (2002) Genome shuffling leads to rapid phenotypic improvement in bacteria. Nature 8, 891-898.
-
(2002)
Nature
, vol.8
, pp. 891-898
-
-
Zhang, Y.X.1
Perry, K.2
Vinci, V.A.3
Powell, K.4
Stemmer, W.P.5
del Cardayré, S.B.6
|