Mycoepoxydiene represents a novel class of fungal metabolites

Tetrahedron Letters

Volumn 40, Issue 8, 1999, Pages 1479-1482

  Cai, Ping ^a   McPhail, Andrew T ^c   Krainer, Eduardo ^b   Katz, Barry ^a   Pearce, Cedric ^a   Boros, Christie ^a   Caceres, Bernardo ^a   Smith, David ^b   Houck, D R ^a  

^a MYCOsearch   (United States)

^b OSI PHARMACEUTICALS INC   (United States)

^c DUKE UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

LACTONE DERIVATIVE; MYCOEPOXYDIENE; UNCLASSIFIED DRUG;

ARTICLE; EXTRACTION; FERMENTATION; FUNGUS CULTURE; NUCLEAR MAGNETIC RESONANCE; STEREOCHEMISTRY; X RAY DIFFRACTION;

EID: 0033582799     PISSN: 00404039     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0040-4039(98)02700-2     Document Type: Article

References (7)

1. Cai, P.; Smith, D.; Katz, B.; Pearce, C.; Venables, D.; Houck, D. J, Nat. Prod., 1998, 61, 290-293.
2. Cai, P.; Smith, D.; Cunningham, B.; Brown-Shimer, S.; Katz, B.; Pearce, C.; Venables, D.; Houck, D. J. Nat. Prod., 1998, 61, 791-795.
3. Cai, P.; Smith, D.; Cunningham, B.; Brown-Shimer, S.; Katz, B.; Pearce, C.; Venables, D.; Houck, D. J. Nat. Prod., in press.
4. 1,2. Production was accomplished on Nunc plates (20 x 20 cm) holding 500 ml of a medium containing 1.8% agar, 0.5% yeast nitrogen base (Sigma), and 1% dextrin (type 1, Sigma) in deionized water. The culture was spread over the entire surface using a glass rod, and then incubated at 22° C for 11 days at which time the culture was well grown over the entire agar surface.
5. w = 0.061) over 1305 reflections with 1 > 3.0σ (I). Crystallographic calculations were performed by use of the Enraf-Nonius Structure Determination Package (SDP 3.0). Tables of atomic positional and thermal parameters, bond lengths and angles have been deposited at the Cambridge Crystallographic Data Centre, 12 Union Road, Cambridge CB2 IEZ, U.K.
6. Liu, J-S and Liang, L. Phytochemislry, 1995, 38, 241-5
7. Spencer, G. F. and Flippen-Anderson, J. L. Phytochemistry, 1981, 20, 2757-2759.