Cytosolic zinc release and clearance in hippocampal neurons exposed to glutamate - The role of pH and sodium

Journal of Neurochemistry

Volumn 117, Issue 2, 2011, Pages 231-243

  Kiedrowski, Lech ^a  

^a UNIVERSITY OF ILLINOIS AT CHICAGO   (United States)

Author keywords

BCECF; FluoZin 3; Fura 2FF; Intracellular pH; Intracellular Zn2+ stores; TPEN

Indexed keywords

2,7 BIS(CARBOXYETHYL) 6 CARBOXYFLUORESCEIN; CALCIUM ION; GLUTAMIC ACID; GLYCINE; GRAMICIDIN; MEGLUMINE; PROTON; SODIUM; ZINC ION;

ACIDIFICATION; ANIMAL CELL; ANIMAL TISSUE; ARTICLE; CALCIUM CELL LEVEL; CELL PH; CHANNEL GATING; CONCENTRATION RESPONSE; CONTROLLED STUDY; CORRELATIONAL STUDY; CULTURE MEDIUM; CYTOSOL; EMBRYO; HIPPOCAMPUS; MOUSE; NERVE CELL CULTURE; NONHUMAN; PRIORITY JOURNAL; PROTON TRANSPORT; SODIUM CELL LEVEL; ZINC CLEARANCE; ZINC METABOLISM; ZINC RELEASE;

ANIMALS; CALCIUM; CELLS, CULTURED; CHELATING AGENTS; CYTOSOL; DOSE-RESPONSE RELATIONSHIP, DRUG; EDETIC ACID; EMBRYO, MAMMALIAN; ETHYLENEDIAMINES; EXCITATORY AMINO ACID AGONISTS; FURA-2; GLUTAMIC ACID; GLYCINE; HIPPOCAMPUS; HYDROGEN-ION CONCENTRATION; MICE; N-METHYLASPARTATE; NEURONS; POLYCYCLIC COMPOUNDS; SODIUM; STATISTICS, NONPARAMETRIC; ZINC;

EID: 79953719401     PISSN: 00223042     EISSN: 14714159     Source Type: Journal    
DOI: 10.1111/j.1471-4159.2011.07194.x     Document Type: Article

References (58)

1. Aizenman E., Stout A. K., Hartnett K. A., Dineley K. E., McLaughlin B. and Reynolds I. J. (2000) Induction of neuronal apoptosis by thiol oxidation: putative role of intracellular zinc release. J. Neurochem. 75, 1878-1888.
2. Berg J. M. and Shi Y. (1996) The galvanization of biology: a growing appreciation for the roles of zinc. Science 271, 1081-1085. (Pubitemid 26075222)
3. Beyersmann D. and Haase H. (2001) Functions of zinc in signaling, proliferation and differentiation of mammalian cells. Biometals 14, 331-341. (Pubitemid 34066636)
4. 2+ with phospholipid membranes. Biophys. Chem. 90, 57-74.
5. Bush A. I. (2003) The metallobiology of Alzheimer's disease. Trends Neurosci. 26, 207-214.
6. Calderone A., Jover T., Mashiko T., Noh K. M., Tanaka H., Bennett M. V. and Zukin R. S. (2004) Late calcium EDTA rescues hippocampal CA1 neurons from global ischemia-induced death. J. Neurosci. 24, 9903-9913. (Pubitemid 39463571)
7. Chao Y. and Fu D. (2004) Kinetic study of the antiport mechanism of an Escherichia coli zinc transporter, ZitB. J. Biol. Chem. 279, 12043-12050. (Pubitemid 38445766)
8. Cheng C. and Reynolds I. J. (1998) Calcium-sensitive fluorescent dyes can report increases in intracellular free zinc concentration in cultured forebrain neurons. J. Neurochem. 71, 2401-2410. (Pubitemid 28531250)
9. Choi D. W., Yokoyama M. and Koh J. (1988) Zinc neurotoxicity in cortical cell culture. Neuroscience 24, 67-79. (Pubitemid 18044242)
10. 2+ exchanger. Neuroreport 9, 3091-3096.
11. Colvin R. A. (2002) pH dependence and compartmentalization of zinc transported across plasma membrane of rat cortical neurons. Am. J. Physiol. Cell Physiol. 282, C317-C329.
12. Cousins R. J., Liuzzi J. P. and Lichten L. A. (2006) Mammalian zinc transport, trafficking, and signals. J. Biol. Chem. 281, 24085-24089.
13. Devinney II M. J., Reynolds I. J. and Dineley K. E. (2005) Simultaneous detection of intracellular free calcium and zinc using fura-2FF and FluoZin-3. Cell Calcium 37, 225-232.
14. 2+ influx is critical for some forms of spreading depression in brain slices. J. Neurosci. 28, 8014-8024.
15. Dineley K. E., Malaiyandi L. M. and Reynolds I. J. (2002) A reevaluation of neuronal zinc measurements: artifacts associated with high intracellular dye concentration. Mol. Pharmacol. 62, 618-627.
16. 2+-dependent reactive oxygen species accumulation. J. Neurochem. 106, 2184-2193.
17. Dufner-Beattie J., Wang F., Kuo Y. M., Gitschier J., Eide D. and Andrews G. K. (2003) The acrodermatitis enteropathica gene ZIP4 encodes a tissue-specific, zinc-regulated zinc transporter in mice. J. Biol. Chem. 278, 33474-33481.
18. Eide D. J. (2006) Zinc transporters and the cellular trafficking of zinc. Biochim. Biophys. Acta 1763, 711-722.
19. Emmetsberger J., Mirrione M. M., Zhou C., Fernandez-Monreal M., Siddiq M. M., Ji K. and Tsirka S. E. (2010) Tissue plasminogen activator alters intracellular sequestration of zinc through interaction with the transporter ZIP4. J. Neurosci. 30, 6538-6547.
20. Gaither L. A. and Eide D. J. (2000) Functional expression of the human hZIP2 zinc transporter. J. Biol. Chem. 275, 5560-5564.
21. Gee K. R., Zhou Z. L., Ton-That D., Sensi S. L. and Weiss J. H. (2002) Measuring zinc in living cells. A new generation of sensitive and selective fluorescent probes. Cell Calcium 31, 245-251.
22. +. Mol. Microbiol. 45, 145-153.
23. 2+ channel. J. Biol. Chem. 281, 9361-9372.
24. Hartley Z. and Dubinsky J. M. (1993) Changes in intracellular pH associated with glutamate excitotoxicity. J. Neurosci. 13, 4690-4699. (Pubitemid 23326340)
25. Hladky S. B. and Haydon D. A. (1972) Ion transfer across lipid membranes in the presence of gramicidin A. I. Studies of the unit conductance channel. Biochim. Biophys. Acta 274, 294-312.
26. Hyrc K. L., Bownik J. M. and Goldberg M. P. (2000) Ionic selectivity of low-affinity ratiometric calcium indicators: mag- Fura-2, Fura-2FF and BTC. Cell Calcium 27, 75-86. (Pubitemid 30150796)
27. Irwin R. P., Lin S.-Z., Long R. T. and Paul S. M. (1994) N-methyl-D-aspartate induces a rapid, reversible, and calcium dependent intracellular acidosis in cultured fetal rat hippocampal neurons. J. Neurosci. 14, 1352-1357.
28. +. Mol. Pharmacol. 56, 619-632.
29. Koh J.-Y., Suh S. W., Gwag B. J., He Y. Y., Hsu C. Y. and Choi D. W. (1996) The role of zinc in selective neuronal death after transient global cerebral ischemia. Science 272, 1013-1016. (Pubitemid 26259319)
30. Lee J. Y., Cole T. B., Palmiter R. D. and Koh J. Y. (2000) Accumulation of zinc in degenerating hippocampal neurons of ZnT3-null mice after seizures: evidence against synaptic vesicle origin. J. Neurosci. 20, RC79.
31. Lee J. M., Zipfel G. J., Park K. H., He Y. Y., Hsu C. Y. and Choi D. W. (2002) Zinc translocation accelerates infarction after mild transient focal ischemia. Neuroscience 115, 871-878. (Pubitemid 35336029)
32. Li N. C., Gawron O. and Bascuas G. (1954) Stability of zinc complexes with glutathione and oxidized glutathione. J. Am. Chem. Soc. 76, 225-229.
33. Li B., Chen N., Luo T., Otsu Y., Murphy T. H. and Raymond L. A. (2002) Differential regulation of synaptic and extra-synaptic NMDA receptors. Nat. Neurosci. 5, 833-834.
34. 2+ extrusion in protection against neuronal excitotoxicity. FASEB J. 3, 2519-2526.
35. 2+ accumulation contributes to synaptic failure, mitochondrial depolarization, and cell death in an acute slice oxygen-glucose deprivation model of ischemia. J. Neurosci. 29, 1105-1114.
36. Ohana E., Segal D., Palty R., Ton-That D., Moran A., Sensi S. L., Weiss J. H., Hershfinkel M. and Sekler I. (2004) A sodium zinc exchange mechanism is mediating extrusion of zinc in mammalian cells. J. Biol. Chem. 279, 4278-4284.
37. 2+ transporter. J. Biol. Chem. 284, 17677-17686.
38. Palmiter R. D. (2004) Protection against zinc toxicity by metallothionein and zinc transporter 1. Proc. Natl Acad. Sci. USA 101, 4918-4923.
39. Palmiter R. D. and Findley S. D. (1995) Cloning and functional characterization of a mammalian zinc transporter that confers resistance to zinc. EMBO J. 14, 639-649.
40. Palmiter R. D. and Huang L. (2004) Efflux and compartmentalization of zinc by members of the SLC30 family of solute carriers. Pflugers Arch. 447, 744-751. (Pubitemid 38241460)
41. Qian J., Xu K., Yoo J., Chen T., Andrews G. K. and Noebels J. (2011) Knockout of Zn transporters Zip-1 and Zip-3 attenuates seizure-induced CA1 neurodegeneration. J. Neurosci. 31, 97-104.
42. 2+ efflux in cultured cortical neurons. J. Neurochem. 107, 1304-1313.
43. + exchanger. J. Biol. Chem. 266, 2739-2745.
44. Rosenmund C. and Westbrook G. L. (1993) Calcium-induced actin depolymerization reduces NMDA channel activity. Neuron 10, 805-814. (Pubitemid 23152037)
45. 3-exchange. J. Physiol. 475, 59-67.
46. Sensi S. L., Canzoniero L. M., Yu S. P., Ying H. S., Koh J. Y., Kerchner G. A. and Choi D. W. (1997) Measurement of intracellular free zinc in living cortical neurons: routes of entry. J. Neurosci. 17, 9554-9564. (Pubitemid 28006399)
47. 2+ pools. Proc. Natl. Acad. Sci. U S A 100, 6157-6162.
48. Sensi S. L., Paoletti P., Bush A. I. and Sekler I. (2009) Zinc in the physiology and pathology of the CNS. Nat. Rev. Neurosci. 10, 780-791.
49. + and inhibition of glycolysis. J. Neurosci. 20, 3139-3146.
50. Smith M. L., von Hanwehr R. and Siesjo B. K. (1986) Changes in extra-and intracellular pH in the brain during and following ischemia in hyperglycemic and in moderately hypoglycemic rats. J. Cereb. Blood Flow Metab. 6, 574-583.
51. 2+-rich vesicles with Zinquin: mechanism of action in lipid environments. Biophys. J. 80, 1538-1546.
52. Taki M., Wolford J. L. and O'Halloran T. V. (2004) Emission ratiometric imaging of intracellular zinc: design of a benzoxazole fluorescent sensor and its application in two-photon microscopy. J. Am. Chem. Soc. 126, 712-713.
53. Thompson R. J., Jackson M. F., Olah M. E., Rungta R. L., Hines D. J., Beazely M. A., MacDonald J. F. and MacVicar B. A. (2008) Activation of pannexin-1 hemichannels augments aberrant bursting in the hippocampus. Science 322, 1555-1559.
54. + exchange is the major mechanism of pH regulation in cultured sympathetic neurons: measurements in single cell bodies and neurites using a fluorescent pH indicator. Neuroscience 22, 1093-1102.
55. Tonder N., Johansen F. F., Frederickson C. J., Zimmer J. and Diemer N. H. (1990) Possible role of zinc in the selective degeneration of dentate hilar neurons after cerebral ischemia in the adult rat. Neurosci. Lett. 109, 247-252.
56. 2+ homeostasis in neuronal dendrites is a downstream consequence of metabolic compromise during extended NMDA exposures. J. Neurosci. 28, 5029-5039.
57. 2+-ATPase in NMDA-induced intracellular acidification. Am. J. Physiol. 277, C717-C727.
58. Yokoyama M., Koh J. and Choi D. W. (1986) Brief exposure to zinc is toxic to cortical neurons. Neurosci. Lett. 71, 351-355.