Thermal killing of human colon cancer cells is associated with the loss of eukaryotic initiation factor 5A

Journal of Cellular Physiology

Volumn 219, Issue 2, 2009, Pages 485-493

  Gosslau, Alexander ^a   Jao, David Li En ^a   Butler, Renee ^a   Liu, Alice Y C ^a   Kuang, Yu Chen ^a  

^a RUTGERS UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BENZYLSULFONYL FLUORIDE; HYDROGEN PEROXIDE; INITIATION FACTOR 5A; EIF-5A; INITIATION FACTOR; PROTEINASE INHIBITOR; RNA BINDING PROTEIN;

ARTICLE; CANCER CELL; CANCER RESEARCH; CELL DEATH; CELL PROLIFERATION; CELL STRAIN CACO 2; CELL STRAIN HCT116; CELL STRAIN HT29; CELL SURVIVAL; COLON CANCER; GENE MUTATION; HEAT SHOCK; HEAT STRESS; NUCLEOTIDE SEQUENCE; OXIDATIVE STRESS; PRIORITY JOURNAL; PROTEIN DEPLETION; PROTEIN FUNCTION; PROTEIN STABILITY; SEQUENCE ANALYSIS; WESTERN BLOTTING; ANIMAL; CELL LINE; CYTOLOGY; DNA FRAGMENTATION; FIBROBLAST; GENETICS; HALF LIFE TIME; HEAT SHOCK RESPONSE; HUMAN; METABOLISM; MOLECULAR GENETICS; PATHOLOGY; PHYSIOLOGY; SEQUENCE ALIGNMENT;

EUKARYOTA;

ANIMALS; BASE SEQUENCE; CACO-2 CELLS; CELL DEATH; CELL LINE; CELL SURVIVAL; DNA FRAGMENTATION; FIBROBLASTS; HALF-LIFE; HEAT-SHOCK RESPONSE; HUMANS; MOLECULAR SEQUENCE DATA; OXIDATIVE STRESS; PEPTIDE INITIATION FACTORS; PROTEASE INHIBITORS; RNA-BINDING PROTEINS; SEQUENCE ALIGNMENT;

EID: 62149084863     PISSN: 00219541     EISSN: None     Source Type: Journal    
DOI: 10.1002/jcp.21696     Document Type: Article

References (48)

1. Beere HM, Green DR. 2001. Stress management - Heat shock protein-70 and the regulation of apoptosis. Trends Cell Biol 11:6-10.
2. Berg K, Hansen MB, Nielsen SE. 1990. A new sensitive bioassay for precise quantification of interferon activity as measured via the mitochondrial dehydrogenase function in cells (MTT-method). Apmis 98:156-162.
3. Bergeron RJ, Weimar WR, Müller R, Zimmerman CO, McCosar BH, Yao H, Smith RE. 1998. Effect of polyamine analogues on hypusine content in JURKAT T-cells. J Med Chem 41:3901-3908.
4. Bergs JW, Franken NA, Haveman J, Geijsen ED, Crezee J, van Bree C. 2007. Hyperthermia, cisplatin and radiation trimodality treatment: A promising cancer treatment? A review from preclinical studies to clinical application. Int J Hyperthermia 23:329-341.
5. Chatterjee I, Gross SR, Kinzy TG, Chen KY. 2006. Rapid depletion of mutant eukaryotic initiation factor 5A at restrictive temperature reveals connections to actin cytoskeleton and cell cycle progression. Mol Genet Genomics 275:264-276.
6. Chen KY, Liu AY. 1997. Biochemistry and function of hypusine formation on eukaryotic initiation factor 5A. Biol Signals 6:105-109.
7. Chen ZP, Yan YP, Ding QJ, Knapp S, Potenza JA, Schugar HJ, Chen KY. 1996. Effects of inhibitors of deoxyhypusine synthase on the differentiation of mouse neuroblastoma and erythroleukemia cells. Cancer Lett 105:233-239.
8. Davidson JF, Schiestl RH. 2001. Mitochondrial respiratory electron carriers are involved in oxidative stress during heat stress in Saccharomyces cerevisiae. Mol Cell Biol 21:8483-8489.
9. Davidson JF, Whyte B, Bissinger PH, Schiestl RH. 1996. Oxidative stress is involved in heat-induced cell death in Saccharomyces cerevisiae. Proc Natl Acad Sci USA 93:5116-5121.
10. DeMeester SL, Buchman TG, Cobb JP. 2001. The heat shock paradox: Does NF-kappaB determine cell fate? FASEB J 15:270-274.
11. Dikomey E, Franzke J. 1992. Effect of heat on induction and repair of DNA strand breaks in X irradiated CHO cells. Int J Radiat Biol 61:221-233.
12. Duncan RF, Hershey JW. 1986. Changes in eIF-4D hypusine modification or abundance are not correlated with translational repression in HeLa cells. J Biol Chem 261:12903-12906.
13. Duncan RF, Hershey JW. 1989. Protein synthesis and protein phosphorylation during heat stress, recovery, and adaptation. J Cell Biol 109:1467-1481.
14. Fuller DJ, Gerner EW. 1982. Polyamines: A dual role in the modulation of cellular sensitivity to heat. Radiat Res 92:439-444.
15. Gerner EW, Holmes DK, Stickney DG, Noterman JA, Fuller DJ. 1980. Enhancement of hyperthermia-induced cytotoxicity by polyamines. Cancer Res 40:432-438.
16. Hildebrandt B, Wust P, Ahlers O, Dieing A, Sreenivasa G, Kerner T, Felix R, Riess H. 2002. The cellular and molecular basis of hyperthermia. Crit Rev Oncol Hematol 43:33-56.
17. Jakus J, Wolff EC, Park MH, Folk JE. 1993. Features of the spermidine-binding site of deoxyhypusine synthase as derived from inhibition studies. Effective inhibition by bis- and mono-guanylated diamines and polyamines. J Biol Chem 268:13151-13159.
18. Jao DL, Chen KY. 2002. Subcellular localization of the hypusine-containing eukaryotic initiation factor 5A by immunofluorescent staining and green fluorescent protein tagging. J Cell Biochem 86:590-600.
19. Jao DL, Chen KY. 2006. Tandem affinity purification revealed the hypusine-dependent binding of eukaryotic initiation factor 5A to the translating 80S ribosomal complex. J Cell Biochem 97:583-598.
20. Jenkins ZA, Haag PG, Johansson HE. 2001. Human eIF5A2 on chromosome 3q25-q27 is a phylogenetically conserved vertebrate variant of eukaryotic translation initiation factor 5A with tissue-specific expression. Genomics 71:101-109.
21. Kaltschmidt B, Heinrich M, Kaltschmidt C. 2002. Stimulus-dependent activation of NF-kappaB specifies apoptosis or neuroprotection in cerebellar granule cells. Neuromol Med 2:299-309.
22. Larkindale J, Knight MR. 2002. Protection against heat stress-induced oxidative damage in Arabidopsis involves calcium, abscisic acid, ethylene, and salicylic acid. Plant Physiol 128:682-695. (Pubitemid 34190882)
23. Li GC, Werb Z. 1982. Correlation between synthesis of heat shock proteins and development of thermotolerance in Chinese hamster fibroblasts. Proc Natl Acad Sci USA 79:3218-3222.
24. Li GC, Mivechi NF, Weitzel G. 1995. Heat shock proteins, thermotolerance, and their relevance to clinical hyperthermia. Int J Hyperthermia 11:459-488.
25. Mariano TM, Siekierka J. 1986. Inhibition of HeLa cell protein synthesis under heat shock conditions in the absence of initiation factor eIF-2 alpha phosphorylation. Biochem Biophys Res Commun 138:519-525.
26. Nishimura K, Murozumi K, Shirahata A, Park MH, Kashiwagi K, Igarashi K. 2005. Independent roles of eIF5A and polyamines in cell proliferation. Biochem J 385:779-785.
27. Nollen EA, Morimoto RI. 2002. Chaperoning signaling pathways: Molecular chaperones as stress-sensing 'heat shock' proteins. J Cell Sci 115:2809-2816.
28. Panniers R, Henshaw EC. 1984. Mechanism of inhibition of polypeptide chain initiation in heat-shocked Ehrlich ascites tumour cells. Eur J Biochem 140:209-214.
29. Park MH. 2006. The post-translational synthesis of a polyamine-derived amino acid, hypusine, in the eukaryotic translation initiation factor 5A (eIF5A). J Biochem 139:161-169.
30. Park MH, Lee YB, Joe YA. 1997. Hypusine is essential for eukaryotic cell proliferation. Biol Signals 6:115-123.
31. Park MH, Wolff EC, Lee YB, Folk JE. 1994. Antiproliferative effects of inhibitors of deoxyhypusine synthase. Inhibition of growth of Chinese hamster ovary cells by guanyl diamines. J Biol Chem 269:27827-27832.
32. Parsell DA, Lindquist S. 1993. The function of heat-shock proteins in stress tolerance: Degradation and reactivation of damaged proteins. Annu Rev Genet 27:437-496.
33. Roti Roti JL, Kampinga HH, Malyapa RS, Wright WD, vander Waal RP, Xu M, 1998. Nuclear matrix as a target for hyperthermic killing of cancer cells. Cell Stress Chaperones 3:245-255.
34. Sakaguchi Y, Stephens LC, Makino M, Kaneko T, Strebel FR, Danhauser LL, Jenkins GN, Bull JM. 1995. Apoptosis in tumors and normal tissues induced by whole body hyperthermia in rats. Cancer Res 55:5459-5464.
35. Samali A, Holmberg CI, Sistonen L, Orrenius S. 1999. Thermotolerance and cell death are distinct cellular responses to stress: Dependence on heat shock proteins. FEBS Lett 461:306-310.
36. Sasaki K, Abid MR, Miyazaki M. 1996. Deoxyhypusine synthase gene is essential for cell viability in the yeast Saccharomyces cerevisiae. FEBS Lett 384:151-154.
37. Schnier J, Schwelberger HG, Smit-McBride Z, Kang HA, Hershey JW. 1991. Translation initiation factor 5A and its hypusine modification are essential for cell viability in the yeast Saccharomyces cerevisiae. Mol Cell Biol 11:3105-3114.
38. Stein U, Rau B, Wust P, Walther W, Schlag PM. 1999. Hyperthermia for treatment of rectal cancer: Evaluation for induction of multidrug resistance gene (mdr1) expression. Int J Cancer 80:5-12.
39. Takeuchi K, Nakamura K, Fujimoto M, Kaino S, Kondoh S, Okita K. 2002. Heat stress-induced loss of eukaryotic initiation factor 5A (eIF-5A) in a human pancreatic cancer cell line, MIA PaCa-2, analyzed by two-dimensional gel electrophoresis. Electrophoresis 23:662-669.
40. Taylor CA, Sun Z, Cliché DO, Ming H, Eshaque B, Jin S, Hopkins MT, Thai B, Thompson JE. 2007. Eukaryotic translation initiation factor 5Ainduces apoptosis in colon cancer cells and associates with the nucleus in response to tumour necrosis factor a signaling. Exp Cell Res 313:437-449.
41. Torrelio BM, Paz MA, Gallop PM. 1987. The formation and stability of the hypusine containing protein in Chinese hamster ovary cells. Biochem Biophys Res Commun 145:1335-1341.
42. Vacca RA, de Pinto MC, Valenti D, Passarella S, Marra E, De Gara L. 2004. Production of reactive oxygen species, alteration of cytosolic ascorbate peroxidase, and impairment of mitochondrial metabolism are early events in heat shock-induced programmed cell death in tobacco Bright-Yellow 2 cells. Plant Physiol 134:1100-1112.
43. van der Zee J. 2002. Heating the patient: A promising approach? Ann Oncol 13:1173-1184.
44. Woessmann W, Meng YH, Mivechi NF. 1999. An essential role for mitogen-activated protein kinases, ERKs, in preventing heat-induced cell death. J Cell Biochem 74:648-662.
45. Wust P, Hildebrandt B, Sreenivasa G, Rau B, Gellermann J, Riess H, Felix R, Schlag PM. 2002. Hyperthermia in combined treatment of cancer. Lancet Oncol 3:487-497.
46. Xu A, Chen KY. 2001. Hypusine is required for a sequence-specific interaction of eukaryotic initiation factor 5A with postsystematic evolution of ligands by exponential enrichment RNA. J Biol Chem 276:2555-2561.
47. Xu A, Jao DL, Chen KY. 2004. Identification of mRNA that binds to eukaryotic initiation factor 5A by affinity co-purification and differential display. Biochem J 384:585-590.
48. Zanelli CF, Maragno AL, Gregio AP, Komili S, Pandolfi JR, Mestriner CA, Lustri WR, Valentini SR. 2006. eIF5A binds to translational machinery components and affects translation in yeast. Biochem Biophys Res Commun 348:1358-1366. (Pubitemid 44291350)