Long-term exposure of INS-1 rat insulinoma cells to linoleic acid and glucose in vitro affects cell viability and function through mitochondrial-mediated pathways

Endocrine

Volumn 39, Issue 2, 2011, Pages 128-138

  Tuo, Ya ^a,b   Wang, Dengfeng ^b,c   Li, Shengbin ^a   Chen, Chen ^b,d  

^a MEDICAL SCHOOL OF XI AN JIAOTONG UNIVERSITY   (China)

^b UNIVERSITY OF QUEENSLAND   (Australia)

^c SICHUAN UNIVERSITY   (China)

^d XI'AN JIAOTONG UNIVERSITY   (China)

Author keywords

Apoptosis; INS 1 cells; Linoleic acid; Mitochondrial; Cell dysfunction

Indexed keywords

CYTOCHROME C; GLUCOSE; LINOLEIC ACID; PROTEIN BAX; PROTEIN BCL 2;

ANIMAL CELL; ANIMAL CELL CULTURE; APOPTOSIS; ARTICLE; CELL FUNCTION; CELL VIABILITY; CONTROLLED STUDY; CULTURE MEDIUM; GENE EXPRESSION; IN VITRO STUDY; INSULIN RELEASE; INSULINOMA; LONG TERM EXPOSURE; MITOCHONDRIAL MEMBRANE POTENTIAL; NON INSULIN DEPENDENT DIABETES MELLITUS; NONHUMAN; PRIORITY JOURNAL; PROTEIN SECRETION; RAT;

EID: 79953654777     PISSN: 1355008X     EISSN: 15590100     Source Type: Journal    
DOI: 10.1007/s12020-010-9432-3     Document Type: Article

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