-
1
-
-
0026721368
-
Contractile protein function in failing and nonfailing human myocardium
-
Hasenfuss G, Mulieri LA, Leavitt BJ, et al. Contractile protein function in failing and nonfailing human myocardium. Basic Res Cardiol. 1992;87(suppl 1): 107-116.
-
(1992)
Basic Res Cardiol
, vol.87
, Issue.SUPPL. 1
, pp. 107-116
-
-
Hasenfuss, G.1
Mulieri, L.A.2
Leavitt, B.J.3
-
2
-
-
0028322990
-
Influence of the force-frequency relationship on haemodynamics and left ventricular function in patients with non-failing hearts and in patients with dilated cardiomyopathy
-
Hasenfuss G, Holubarsch C, Hermann HP, Astheimer K, Pieske B, Just H. Influence of the force-frequency relationship on haemodynamics and left ventricular function in patients with non-failing hearts and in patients with dilated cardiomyopathy. Eur Heart J. 1994;15:164-170.
-
(1994)
Eur Heart J
, vol.15
, pp. 164-170
-
-
Hasenfuss, G.1
Holubarsch, C.2
Hermann, H.P.3
Astheimer, K.4
Pieske, B.5
Just, H.6
-
3
-
-
0029095444
-
Alterations in intracellular calcium handling associated with the inverse force-frequency relation in human dilated cardiomyopathy
-
Pieske B, Kretschmann B, Meyer M, et al. Alterations in intracellular calcium handling associated with the inverse force-frequency relation in human dilated cardiomyopathy. Circulation. 1995;92:1169-1178.
-
(1995)
Circulation
, vol.92
, pp. 1169-1178
-
-
Pieske, B.1
Kretschmann, B.2
Meyer, M.3
-
6
-
-
0035822690
-
Heart failure after myocardial infarction: altered excitation-contraction coupling
-
Gomez AM, Guatimosim S, Dilly KW, Vassort G, Lederer WJ. Heart failure after myocardial infarction: altered excitation-contraction coupling. Circulation. 2001;104:688-693.
-
(2001)
Circulation
, vol.104
, pp. 688-693
-
-
Gomez, A.M.1
Guatimosim, S.2
Dilly, K.W.3
Vassort, G.4
Lederer, W.J.5
-
7
-
-
3042763171
-
2+/calmodulin-dependent protein kinase II phosphorylation regulates the cardiac ryanodine receptor
-
2+/calmodulin-dependent protein kinase II phosphorylation regulates the cardiac ryanodine receptor. Circ Res. 2004;94:e61-e70.
-
(2004)
Circ Res
, vol.94
-
-
Wehrens, X.H.1
Lehnart, S.E.2
Reiken, S.R.3
Marks, A.R.4
-
8
-
-
0034640113
-
PKA phosphorylation dissociates FKBP12.6 from the calcium release channel (ryanodine receptor): defective regulation in failing hearts
-
Marx SO, Reiken S, Hisamatsu Y, et al. PKA phosphorylation dissociates FKBP12.6 from the calcium release channel (ryanodine receptor): defective regulation in failing hearts. Cell. 2000;101:365-376.
-
(2000)
Cell
, vol.101
, pp. 365-376
-
-
Marx, S.O.1
Reiken, S.2
Hisamatsu, Y.3
-
11
-
-
0022980843
-
Beta1-and beta2-adrenergic-receptor subpopulations in nonfailing and failing human ventricular myocardium: coupling of both receptor subtypes to muscle contraction and selective beta1-receptor down-regulation in heart failure
-
Bristow MR, Ginsburg R, Umans V, et al. Beta1-and beta2-adrenergic-receptor subpopulations in nonfailing and failing human ventricular myocardium: coupling of both receptor subtypes to muscle contraction and selective beta1-receptor down-regulation in heart failure. Circ Res. 1986;59:297-309.
-
(1986)
Circ Res
, vol.59
, pp. 297-309
-
-
Bristow, M.R.1
Ginsburg, R.2
Umans, V.3
-
12
-
-
0021194420
-
Plasma norepinephrine as a guide to prognosis in patients with chronic congestive heart failure
-
Cohn JN, Levine TB, Olivari MT, et al. Plasma norepinephrine as a guide to prognosis in patients with chronic congestive heart failure. N Engl J Med. 1984;311:819-823.
-
(1984)
N Engl J Med
, vol.311
, pp. 819-823
-
-
Cohn, J.N.1
Levine, T.B.2
Olivari, M.T.3
-
13
-
-
0023130366
-
Deficient production of cyclic AMP: pharmacologic evidence of an important cause of contractile dysfunction in patients with end-stage heart failure
-
Feldman MD, Copelas L, Gwathmey JK, et al. Deficient production of cyclic AMP: pharmacologic evidence of an important cause of contractile dysfunction in patients with end-stage heart failure. Circulation. 1987;75:331-339.
-
(1987)
Circulation
, vol.75
, pp. 331-339
-
-
Feldman, M.D.1
Copelas, L.2
Gwathmey, J.K.3
-
14
-
-
0034623819
-
The beta2-adrenergic receptor delivers an antiapoptotic signal to cardiac myocytes through Gi-dependent coupling to phosphatidylinositol 3'-kinase
-
Chesley A, Lundberg MS, Asai T, et al. The beta2-adrenergic receptor delivers an antiapoptotic signal to cardiac myocytes through Gi-dependent coupling to phosphatidylinositol 3'-kinase. Circ Res. 2000;87:1172-1179.
-
(2000)
Circ Res
, vol.87
, pp. 1172-1179
-
-
Chesley, A.1
Lundberg, M.S.2
Asai, T.3
-
15
-
-
0035852634
-
Dual modulation of cell survival and cell death by beta2-adrenergic signaling in adult mouse cardiac myocytes
-
Zhu WZ, Zheng M, Koch WJ, Lefkowitz RJ, Kobilka BK, Xiao RP. Dual modulation of cell survival and cell death by beta2-adrenergic signaling in adult mouse cardiac myocytes. Proc Natl Acad Sci U S A. 2001;98: 1607-1612.
-
(2001)
Proc Natl Acad Sci U S A
, vol.98
, pp. 1607-1612
-
-
Zhu, W.Z.1
Zheng, M.2
Koch, W.J.3
Lefkowitz, R.J.4
Kobilka, B.K.5
Xiao, R.P.6
-
17
-
-
0023189660
-
Abnormal intracellular calcium handling in myocardium from patients with end-stage heart failure
-
Gwathmey JK, Copelas L, MacKinnon R, Schoen FJ, Feldman MD, Grossman W & Morgan JP. Abnormal intracellular calcium handling in myocardium from patients with end-stage heart failure. Circ Res. 1987;61:70-76.
-
(1987)
Circ Res
, vol.61
, pp. 70-76
-
-
Gwathmey, J.K.1
Copelas, L.2
MacKinnon, R.3
Schoen, F.J.4
Feldman, M.D.5
Grossman, W.6
Morgan, J.P.7
-
18
-
-
0026642036
-
Isolated ventricular myocytes from failing and non-failing human heart; the relation of age and clinical status of patients to isoproterenol response
-
Harding SE, Jones SM, O'Gara P, del Monte F, Vescovo G, Poole-Wilson PA. Isolated ventricular myocytes from failing and non-failing human heart; the relation of age and clinical status of patients to isoproterenol response. J Mol Cell Cardiol. 1992;24:549-564.
-
(1992)
J Mol Cell Cardiol
, vol.24
, pp. 549-564
-
-
Harding, S.E.1
Jones, S.M.2
O'Gara, P.3
del Monte, F.4
Vescovo, G.5
Poole-Wilson, P.A.6
-
19
-
-
0032190893
-
Contribution of abnormal sarcoplasmic reticulum ATPase activity to systolic and diastolic dysfunction in human heart failure
-
Schmidt U, Hajjar RJ, Helm PA, Kim CS, Doye AA, Gwathmey JK. Contribution of abnormal sarcoplasmic reticulum ATPase activity to systolic and diastolic dysfunction in human heart failure. J Mol Cell Cardiol. 1998;30:1929-1937.
-
(1998)
J Mol Cell Cardiol
, vol.30
, pp. 1929-1937
-
-
Schmidt, U.1
Hajjar, R.J.2
Helm, P.A.3
Kim, C.S.4
Doye, A.A.5
Gwathmey, J.K.6
-
20
-
-
0025325158
-
Role of intracellular calcium handling in force-interval relationships of human ventricular myocardium
-
Gwathmey JK, Slawsky MT, Hajjar RJ, Briggs GM, Morgan JP. Role of intracellular calcium handling in force-interval relationships of human ventricular myocardium. J Clin Invest. 1990;85;1599-1613.
-
(1990)
J Clin Invest
, vol.85
, pp. 1599-1613
-
-
Gwathmey, J.K.1
Slawsky, M.T.2
Hajjar, R.J.3
Briggs, G.M.4
Morgan, J.P.5
-
22
-
-
1842294625
-
Defective excitation-contraction coupling in experimental cardiac hypertrophy and heart failure
-
Gomez AM, Valdivia HH, Cheng H, et al. Defective excitation-contraction coupling in experimental cardiac hypertrophy and heart failure. Science. 1997;276:800-806.
-
(1997)
Science
, vol.276
, pp. 800-806
-
-
Gomez, A.M.1
Valdivia, H.H.2
Cheng, H.3
-
23
-
-
0032189260
-
Transgenic expression of replication-restricted enteroviral genomes in heart muscle induces defective excitation-contraction coupling and dilated cardiomyopathy
-
Wessely R, Klingel K, Santana LF, et al. Transgenic expression of replication-restricted enteroviral genomes in heart muscle induces defective excitation-contraction coupling and dilated cardiomyopathy. J Clin Invest. 1998;102:1444-1453.
-
(1998)
J Clin Invest
, vol.102
, pp. 1444-1453
-
-
Wessely, R.1
Klingel, K.2
Santana, L.F.3
-
24
-
-
0035941418
-
Dilated cardiomyopathy and sudden death resulting from constitutive activation of protein kinase α
-
Antos CL, Frey N, Marx SO, et al. Dilated cardiomyopathy and sudden death resulting from constitutive activation of protein kinase α. Circ Res. 2001;89:997-1004.
-
(2001)
Circ Res
, vol.89
, pp. 997-1004
-
-
Antos, C.L.1
Frey, N.2
Marx, S.O.3
-
26
-
-
0001078987
-
Alterations of calcium-regulatory proteins in heart failure
-
Hasenfuss G. Alterations of calcium-regulatory proteins in heart failure. Cardiovasc Res. 1998;37:279-289.
-
(1998)
Cardiovasc Res
, vol.37
, pp. 279-289
-
-
Hasenfuss, G.1
-
27
-
-
0027426069
-
Calcium sparks: elementary events underlying excitation-contraction coupling in heart muscle
-
Cheng H, Lederer WJ, Cannell MB. Calcium sparks: elementary events underlying excitation-contraction coupling in heart muscle. Science. 1993;262:740-744.
-
(1993)
Science
, vol.262
, pp. 740-744
-
-
Cheng, H.1
Lederer, W.J.2
Cannell, M.B.3
-
28
-
-
0026099413
-
Impairment of the myocardial ultrastructure and changes of the cytoskeleton in dilated cardiomyopathy
-
Schaper J, Froede R, Hein S, et al. Impairment of the myocardial ultrastructure and changes of the cytoskeleton in dilated cardiomyopathy. Circulation. 1991;83:504-514.
-
(1991)
Circulation
, vol.83
, pp. 504-514
-
-
Schaper, J.1
Froede, R.2
Hein, S.3
-
29
-
-
33645236491
-
Orphaned ryanodine receptors in the failing heart
-
Song LS, Sobie EA, McCulle S, Lederer WJ, Balke CW, Cheng H. Orphaned ryanodine receptors in the failing heart. Proc Natl Acad Sci U S A. 2006;103: 4305-4310.
-
(2006)
Proc Natl Acad Sci U S A
, vol.103
, pp. 4305-4310
-
-
Song, L.S.1
Sobie, E.A.2
McCulle, S.3
Lederer, W.J.4
Balke, C.W.5
Cheng, H.6
-
30
-
-
0035916903
-
Decreased sarcoplasmic reticulum calcium content is responsible for defective excitation-contraction coupling in canine heart failure
-
Hobai IA & O'Rourke B. Decreased sarcoplasmic reticulum calcium content is responsible for defective excitation-contraction coupling in canine heart failure. Circulation. 2001;103:1577-1584.
-
(2001)
Circulation
, vol.103
, pp. 1577-1584
-
-
Hobai, I.A.1
O'Rourke, B.2
-
31
-
-
26244467287
-
Phosphodiesterase 4D deficiency in the ryanodine-receptor complex promotes heart failure and arrhythmias
-
Lehnart SE, Wehrens XH, Reiken S, et al. Phosphodiesterase 4D deficiency in the ryanodine-receptor complex promotes heart failure and arrhythmias. Cell. 2005;123:25-35.
-
(2005)
Cell
, vol.123
, pp. 25-35
-
-
Lehnart, S.E.1
Wehrens, X.H.2
Reiken, S.3
-
33
-
-
0037414827
-
Protein kinase A phosphorylation of the cardiac calcium release channel (ryanodine receptor) in normal and failing hearts. Role of phosphatases and response to isoproterenol
-
Reiken S, Gaburjakova M, Guatimosim S, et al. Protein kinase A phosphorylation of the cardiac calcium release channel (ryanodine receptor) in normal and failing hearts. Role of phosphatases and response to isoproterenol. J Biol Chem. 2003;278:444-453.
-
(2003)
J Biol Chem
, vol.278
, pp. 444-453
-
-
Reiken, S.1
Gaburjakova, M.2
Guatimosim, S.3
-
34
-
-
0037708928
-
FKBP12.6 deficiency and defective calcium release channel (ryanodine receptor) function linked to exercise-induced sudden cardiac death
-
Wehrens XH, Lehnart SE, Huang F. FKBP12.6 deficiency and defective calcium release channel (ryanodine receptor) function linked to exercise-induced sudden cardiac death. Cell. 2003;113:829-840.
-
(2003)
Cell
, vol.113
, pp. 829-840
-
-
Wehrens, X.H.1
Lehnart, S.E.2
Huang, F.3
-
36
-
-
66449097490
-
2+/calmodulin-dependent kinase II in the transition from pressure overload-induced cardiac hypertrophy to heart failure in mice
-
2+/calmodulin-dependent kinase II in the transition from pressure overload-induced cardiac hypertrophy to heart failure in mice. J Clin Invest. 2009;119:1230-1240.
-
(2009)
J Clin Invest
, vol.119
, pp. 1230-1240
-
-
Ling, H.1
Zhang, T.2
Pereira, L.3
-
37
-
-
31444432542
-
Ryanodine receptor/calcium release channel PKA phosphorylation: a critical mediator of heart failure progression
-
Wehrens XH, Lehnart SE, Reiken S, Vest JA, Wronska A, Marks AR. Ryanodine receptor/calcium release channel PKA phosphorylation: a critical mediator of heart failure progression. Proc Natl Acad Sci U S A. 2006;103: 511-518.
-
(2006)
Proc Natl Acad Sci U S A
, vol.103
, pp. 511-518
-
-
Wehrens, X.H.1
Lehnart, S.E.2
Reiken, S.3
Vest, J.A.4
Wronska, A.5
Marks, A.R.6
-
38
-
-
77953418093
-
Role of CaMKIIδ phosphorylation of the cardiac ryanodine receptor in the force frequency relationship and heart failure
-
Kushnir A, Shan J, Betzenhauser MJ, Reiken S, Marks AR. Role of CaMKII( phosphorylation of the cardiac ryanodine receptor in the force frequency relationship and heart failure. Proc Natl Acad Sci U S A. 2010;107: 10274-10279.
-
(2010)
Proc Natl Acad Sci U S A
, vol.107
, pp. 10274-10279
-
-
Kushnir, A.1
Shan, J.2
Betzenhauser, M.J.3
Reiken, S.4
Marks, A.R.5
-
39
-
-
0036450344
-
2+ flux pathways in cardiomyocytes from rabbits with infarct-induced left-ventricular dysfunction
-
2+ flux pathways in cardiomyocytes from rabbits with infarct-induced left-ventricular dysfunction. Pflugers Arch. 2002;444:360-371.
-
(2002)
Pflugers Arch
, vol.444
, pp. 360-371
-
-
Neary, P.1
Duncan, A.M.2
Cobbe, S.M.3
Smith, G.L.4
-
40
-
-
0033199681
-
Tetracaine can inhibit contractions initiated by a voltage-sensitive release mechanism in guinea-pig ventricular myocytes
-
Mason CA, Ferrier GR. Tetracaine can inhibit contractions initiated by a voltage-sensitive release mechanism in guinea-pig ventricular myocytes. J Physiol. 1999;519(pt 3):851-865.
-
(1999)
J Physiol
, vol.519
, Issue.PART 3
, pp. 851-865
-
-
Mason, C.A.1
Ferrier, G.R.2
-
41
-
-
22144480949
-
Enhancing calstabin binding to ryanodine receptors improves cardiac and skeletal muscle function in heart failure
-
Wehrens XH, Lehnart SE, Reiken S, et al. Enhancing calstabin binding to ryanodine receptors improves cardiac and skeletal muscle function in heart failure. Proc Natl Acad Sci U S A. 2005;102: 9607-9612.
-
(2005)
Proc Natl Acad Sci U S A
, vol.102
, pp. 9607-9612
-
-
Wehrens, X.H.1
Lehnart, S.E.2
Reiken, S.3
-
42
-
-
0037469180
-
FKBP12.6-mediated stabilization of calcium-release channel (ryanodine receptor) as a novel therapeutic strategy against heart failure
-
Yano M, Kobayashi S, Kohno M, et al. FKBP12.6-mediated stabilization of calcium-release channel (ryanodine receptor) as a novel therapeutic strategy against heart failure. Circulation. 2003;107:477-484.
-
(2003)
Circulation
, vol.107
, pp. 477-484
-
-
Yano, M.1
Kobayashi, S.2
Kohno, M.3
-
43
-
-
61949338001
-
Hypernitrosylated ryanodine receptor calcium release channels are leaky in dystrophic muscle
-
Bellinger AM, Reiken S, Carlson C, et al. Hypernitrosylated ryanodine receptor calcium release channels are leaky in dystrophic muscle. Nat Med. 2009;15:325-330.
-
(2009)
Nat Med
, vol.15
, pp. 325-330
-
-
Bellinger, A.M.1
Reiken, S.2
Carlson, C.3
-
44
-
-
45749100010
-
2+ release channel/ryanodine receptor 2 causes seizures and sudden cardiac death in mice
-
2+ release channel/ryanodine receptor 2 causes seizures and sudden cardiac death in mice. J Clin Invest. 2008;118:2230-2245.
-
(2008)
J Clin Invest
, vol.118
, pp. 2230-2245
-
-
Lehnart, S.E.1
Mongillo, M.2
Bellinger, A.3
-
45
-
-
0037133555
-
Propranolol prevents the development of heart failure by restoring FKBP12.6-mediated stabilization of ryanodine receptor
-
Doi M, Yano M, Kobayashi S, et al. Propranolol prevents the development of heart failure by restoring FKBP12.6-mediated stabilization of ryanodine receptor. Circulation. 2002;105:1374-1379.
-
(2002)
Circulation
, vol.105
, pp. 1374-1379
-
-
Doi, M.1
Yano, M.2
Kobayashi, S.3
-
46
-
-
0038662725
-
Beta-blockers restore calcium release channel function and improve cardiac muscle performance in human heart failure
-
Reiken S, Wehrens XH, Vest JA, et al. Beta-blockers restore calcium release channel function and improve cardiac muscle performance in human heart failure. Circulation. 2003;107:2459-2466.
-
(2003)
Circulation
, vol.107
, pp. 2459-2466
-
-
Reiken, S.1
Wehrens, X.H.2
Vest, J.A.3
-
47
-
-
10744228679
-
Valsartan restores sarcoplasmic reticulum function with no appreciable effect on resting cardiac function in pacing-induced heart failure
-
Okuda S, Yano M, Doi M, et al. Valsartan restores sarcoplasmic reticulum function with no appreciable effect on resting cardiac function in pacing-induced heart failure. Circulation. 2004;109:911-919.
-
(2004)
Circulation
, vol.109
, pp. 911-919
-
-
Okuda, S.1
Yano, M.2
Doi, M.3
|