Diminished post-rest potentiation of contractile force in human dilated cardiomyopathy: Functional evidence for alterations in intracellular Ca2+ handling

Journal of Clinical Investigation

Volumn 98, Issue 3, 1996, Pages 764-776

  Pieske, Burkert ^a   Sütterlin, Melanie ^a   Schmidt Schweda, Stephan ^a   Minami, Kitzatomo ^b   Meyer, Markus ^a   Olschewski, Manfred ^a   Holubarsch, Christian ^a   Just, Hanjörg ^a   Hasenfuss, Gerd ^a  

^a UNIVERSITY OF FREIBURG   (Germany)

^b RUHR UNIVERSITY BOCHUM   (Germany)

Author keywords

aequorin; calcium handling; excitation contraction coupling; myocardial function; sarcoplasmic reticulum

Indexed keywords

AEQUORIN; CALCIUM ION;

ADULT; ARTICLE; CALCIUM CELL LEVEL; CALCIUM CURRENT; CLINICAL ARTICLE; CONTROLLED STUDY; EXCITATION CONTRACTION COUPLING; FEMALE; HEART DILATATION; HEART FAILURE; HEART MUSCLE CONTRACTILITY; HUMAN; HUMAN TISSUE; MALE; MUSCLE TONE; MUSCLE TWITCH; POST TETANIC POTENTIATION; PRIORITY JOURNAL; SARCOPLASMIC RETICULUM;

EID: 0029862043     PISSN: 00219738     EISSN: None     Source Type: Journal    
DOI: 10.1172/JCI118849     Document Type: Article

References (68)

1. Koch-Weser, J., and J.R. Blinks. 1963. The influence of the interval between beats on myocardial contractility. Pharmacol. Rev. 15:601-652.
2. Allen, D.G., B.R. Jewell, and E.H. Wood. 1976. Studies of the contractility of mammalian myocardium at low rates of stimulation. J Physiol. (Lond.) 254:1-18.
3. Bers, D.M. 1985. Calcium influx and sarcoplasmic reticulum calcium release in cardiac muscle activation during post-rest recovery. Am. J. Physiol. 248: H366-H381.
4. Anderson, T.W., C. Hirsch, and F. Kavaler. 1977. Mechanism of activation of contraction in frog ventricular muscle. Circ. Res. 41:472-480.
5. Kort, A.A., and E.G. Lakatta. 1988. Spontaneous sarcoplasmic reticulum calcium release in rat and rabbit cardiac muscle: relation to transient and rested-state twitch tension. Circ. Res. 63:969-979.
6. Fabiato, A. 1985. Simulated calcium current can both cause calcium loading and trigger calcium release from the sarcoplasmic reticulum of a skinned cardiac Purkinje fiber. J. Gen. Physiol. 85:291-320.
7. Gwathmey, J.K., L. Copelas, R. MacKinnon, F.J. Schoen, M.D. Feldman, W. Grossman, and J.P. Morgan. 1987. Abnormal intracellular calcium handling in myocardium from patients with end-stage heart failure. Circ. Res. 61:70-76.
8. Morgan, J.P., R.E. Erny, P.D. Allen, W. Grossman, and J.K. Gwathmey. 1990. Abnormal intracellular calcium handling, a major cause of systolic and diastolic dysfunction in ventricular myocardium from patients with heart failure. Circulation. 81(Suppl.III):21-32.
9. Hasenfuss, G., L.A. Mulieri, J.B. Leavitt, P.D. Allen, J.R. Haeberle, and N.R. Alpert. 1992. Alteration of contractile function and excitation-contraction coupling in dilated cardiomyopathy. Circ. Res. 70:1225-1232.
10. Beuckelmann, D.J., M. Näbauer, and E. Erdmann. 1992. Intracellular calcium handling in isolated ventricular myocytes from patients with terminal heart failure. Circulation. 85:1046-1055.
11. Mulieri, L.A., G. Hasenfuss, J.B. Leavitt, P.D. Allen, and N.R. Alpert. 1992. Altered myocardial force-frequency relation in human heart failure. Circulation. 85:1743-1750.
12. Pieske, B., G. Hasenfuss, Ch. Holubarsch, R. Schwinger, M. Böhm, and H. Just. 1992. Alterations of the force-frequency-relationship in the failing human heart depend on the underlying cardiac disease. Basic Res. Cardiol. 87(1): 213-221.
13. Pieske, B., B. Kretschmann, B. Kretschmann, M. Meyer, Ch. Holubarsch, J. Weirich, H. Posival, K. Minami, H. Just, and G. Hasenfuss. 1995. Alterations in intracellular calcium handling associated with the inverse force-frequency relation in human diluted cardiomyopathy. Circulation. 92:1169-1178.
14. Gwathmey, J.K., M.T. Slawsky, R.J. Hajjar, G.M. Briggs, and J.P. Morgan. 1990. Role of intracellular calcium handling in force-interval relationships of human ventricular myocardium. J. Clin. Invest. 85:1599-1613.
15. 2+-ATPase in failing and nonfailing human myocardium. Circ. Res. 75:434-442.
16. 2+ uptake by cardiac sarcoplasmic reticulum from patients with idiopathic dilated cardiomyopathy. Circ. Res. 65:1141-1144.
17. 2+ transporting ATPase, phospholamban, and calsequestrin levels in nonfailing and failing human myocardium. Circulation. 90:653-657.
18. 2+ ATPase gene expression in the human ventricle during end-stage heart failure. J. Clin. Invest. 85:305-309.
19. 2+-ATPase gene. Circ. Res. 71:1357-1365.
20. Meyer, M., W. Schillinger, B. Pieske, Holubarsch, C. Heilmann, H. Posival, G. Kuwajima, K. Mikoshiba, H. Just, and G. Hasenfuss. 1995. Alterations of sarcoplasmic reticulum proteins in failing human dilated cardiomyopathy. Circulation. 92:778-784.
21. Limas, C.J., M.T. Olivari, I.F. Goldenberg, T.B. Levine, D.G. Benditt, and A. Simon. 1987. Calcium uptake by cardiac sarcoplasmic reticulum in human dilated cardiomyopathy. Cardiovasc. Res. 21:601-605.
22. 2+-exchanger in end-stage human heart failure. Circ. Res. 75:443-453.
23. 2+ exchange activity in patients with end-stage heart failure. Cardiovasc. Res. 31:48-54.
24. Mulieri, L.A., G. Hasenfuss, F. Ittleman, E.M. Blanchard, and N.R. Alpert. 1992. Protection of human left ventricular myocardium from cutting injury with 2,3-butanedion monoxime. Circ. Res. 65:1441-1444.
25. Kihara, Y., and J. Morgan. 1989. A comparative study of three methods for intracellular loading of the calcium indicator aequorin in ferret papillary muscles. Biochem. Biophys. Res. Com. 162:402-407.
26. i and force in ferret cardiac muscle after chemical loading of aequorin. Am. J. Physiol. 265:C1703-C1710.
27. Harding, S.E., S.M. Jones, P. O'Gara, G. Vescovo, and P.A. Poole-Wilson. 1990. Reduced β-agonist sensitivity in single atrial cells from failing human hearts. Am. J. Physiol. 259:H1009-H1014.
28. 2+ sensitivity. J.A. Lee and D.G. Allen, editors. Oxford University Press, Oxford, UK. 242-282.
29. Na-Ca in cardiac myocytes. Science (Wash. DC). 248:376-378.
30. 2+ loading in cardiac muscle preparations based on rapid cooling contractures. Am. J. Physiol. 256:C109-C120.
31. 2+ uptake in resting single myocytes of the rat heart: Comparison with guinea-pig. J. Mol. Cell. Cardiol. 22:1221-1229.
32. Banijamali, H.S., W.D. Gao, B.R. MacIntosh, and H.E.D.J. ter Keurs. 1991. Force-interval relations of twitches and cold contractures in rat cardiac trabeculae. Effect of ryanodine. Circ. Res. 69:937-948.
33. 2+ transport revealed by rapidly cooling rabbit ventricular muscle. J. Gen. Physiol. 88:437-473.
34. 2+ content in rabbit ventricular myocytes. Am. J. Physiol. 257:H1369-H1377.
35. Wankerl, M., M. Böhm, I. Morano, J.C. Rüegg, M. Eichhorn, and E. Erdmann. 1990. Calcium sensitivity and myosin light chain pattern of atrial and ventricular skinned cardiac fibres from patients with various kinds of cardiac disease. J. Mol. Cell. Cardiol. 22:1425-1438.
36. 2+] in intact human myocardium. Circulation. 82: 1266-1278.
37. Schwinger, R.H.G., M. Böhm, A. Koch, U. Schmidt, I. Morano, H.J. Eissner, P. Überfuhr, B. Reichart, and E. Erdmann. 1994. The failing human heart is unable to use the Frank-Starling mechanism. Circ. Res. 74:959-969.
38. 2+ concentration. J. Physiol. 192:479-192.
39. Ezzaher, A., N. Bouanani, and B. Crozatier. 1992. Force-frequency relations and response to ryanodine in failing rabbit hearts. Am. J. Physiol. 263: H1710-1715.
40. 2+-ATPase activity of cardiac sarcoplasmic reticulum from dilated cardiomyopathy patients compared with patients with nonfailing hearts. Circulation. 92:3220-3228.
41. Brillantes, A.M., P. Allen, T. Takahashi, S. Izumo, and A.R. Marks. 1992. Differences in cardiac calcium release channels (ryanodine receptor) expression in myocardium from patients with end-stage heart failure caused by ischemic versus dilated cardiomyopathy. Circ. Res. 71:18-26.
42. Holmberg, S.R.M., and A.J. Williams. 1992. The calcium-release channel from cardiac sarcoplasmic reticulum: function in the failing and acutely ischemic heart. Basic Res. Cardiol. 87(1):255-268.
43. 2+ release activity of the sarcoplasmic reticulum in dilated cardiomyopathy. Circulation. 85:518-525.
44. 2+ accumulation in nonfailing and failing human myocardium. Circulation. 92:2504-2510.
45. Bers, D.M., R.A. Bassani, J.W.M. Bassani, S. Baudet, and L.V. Hryshko. 1993. Paradoxical twitch potentiation after rest in cardiac muscle: increased fractional release of SR calcium. J. Mol. Cell. Cardiol. 25:1047-1057.
46. 2+ current in cardiac cells. Am. J. Physiol. 268:H916-H920.
47. 2+ content in cardiac myocytes. Am. J. Physiol. 268:C1313-C1329.
48. 2+ content of cardiac SR assessed by caffeine and rapid cooling contractures. Am. J. Physiol. 253:C408-415.
49. Malecot, C.O., and B.G. Katzung. 1987. Use-dependence of ryanodine effects on postrest contraction in ferret cardiac muscle. Circ. Res. 60:560-567.
50. Bose, D., L.V. Hryshko, B.W. King, and T. Chau. 1988. Control of interval-force relation in canine ventricular myocardium studied with ryanodine. Br. J. Pharmacol. 95:811-820.
51. 2+ after ryanodine in rat ventricular myocytes. Am. J. Physiol. 265:H604-H615.
52. 2+ release channel. Am. J. Physiol. 253:C364-C368.
53. 2+ pump: ryanodine and voltage sensitivity. Circ. Res. 65:334-342.
54. 2+ exchange and consequences for relaxation in isolated cardiac myocytes from guinea pigs. Am. J. Physiol. 267:H477-H487.
55. 2+ exchanger in mammalian cardiac myocytes. J. Physiol. 488.3:623-631.
56. 2+ content. Am. J. Physiol. 250:H654-661.
57. Wolska, B.M., and B. Lewartowski. 1991. Calcium in the in situ mitochondria of rested and stimulated myocardium. J. Mol. Cell. Cardiol. 23:217-226.
58. 2+ concentration in cardiac muscle from rabbits. Am. J. Physiol. 253:C398-C407.
59. Hansford, R.G., and E.G. Lakatta. 1987. Ryanodine releases calcium from sarcoplasmic reticulum in calcium-tolerant rat cardiac myocytes. J. Physiol. (Lond.). 390:453-467.
60. Maisel, A.S., C. Philips, M.C. Michel, M.G. Ziegler, and S.M. Carter. 1989. Regulation of cardiac β-adrenergic receptors by captopril: implications for congestive heart failure. Circulation. 80:669-675.
61. 2+ handling and β-adrenergic responsiveness of myocardium from rats with postinfarct failure. Circ. Res. 71:797-807.
62. Wohlfahrt, B., and T.M. Noble. 1982. The cardiac excitation-contraction cycle. Pharmacol. Ther. 16:1-43.
63. Piot, C., S. Lemaire, B. Albat, J. Seguin, J. Nargeot, and S. Richard. 1996. High frequency-induced upregulation of human cardiac calcium currents. Circulation. 93:120-128.
64. Phillips, P.J., J.K. Gwathmey, M.D. Feldman, F.J. Schoen, W. Grossman, and J.P. Morgan. 1990. Post-extrasystolic potentiation and the force-frequency relationship: Differential augmentation of myocardial contractility in working myocardium from patients with end-stage heart failure. J. Mol. Cell. Cardiol. 22:99-110.
65. 2+ selective microelectrodes. Circ. Res. 58:769-782.
66. Beuckelmann, D.J., M. Näbauer, and E. Erdmann. 1991. Characteristics of calcium-currents in isolated human ventricular myocytes from patients with terminal heart failure. J. Mol. Cell. Cardiol. 23:929-937.
67. Nanasi, P.P., A. Varro, and D.A. Lathrop. 1992. Ionic currents in ventricular myocytes isolated from the heart of a patient with idiopathic cardiomyopathy. Cardioscience. 67:115-118.
68. Paradise, N.F., J.L. Schmitter, and J.M. Surmitis. 1981. Criteria for adequate oxygenation of isometric kitten papillary muscle. Am. J. Physiol. 241: H348-H353.