The hydrophobic dipeptide Leu-Ile inhibits immobility induced by repeated forced swimming via the induction of BDNF

Behavioural Brain Research

Volumn 220, Issue 2, 2011, Pages 271-280

  Furukawa Hibi, Yoko ^a   Nitta, Atsumi ^b   Ikeda, Takeshi ^c   Morishita, Koji ^c   Liu, Wenting ^a   Ibi, Daisuke ^a   Alkam, Tursun ^d,e   Nabeshima, Toshitaka ^d,e   Yamada, Kiyofumi ^a  

^a NAGOYA UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

^b UNIVERSITY OF TOYAMA   (Japan)

^c KYOWA HAKKO BIO CO   (Japan)

^d MEIJO UNIVERSITY   (Japan)

^e The Academic Frontier Project for Private Universities   (Japan)

Author keywords

Brain derived neurotrophic factor; BrdU; Forced swim test; Leucyl isoleucine; Mammalian target of rapamycin; Reverse transcription polymerase chain reaction; Tyrosine kinase receptor B

Indexed keywords

ANTIDEPRESSANT AGENT; BRAIN DERIVED NEUROTROPHIC FACTOR; BROXURIDINE; DIPEPTIDE; LEUCYLISOLEUCINE DIPEPTIDE; MAMMALIAN TARGET OF RAPAMYCIN; MESSENGER RNA; PROTEIN KINASE B; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CELL COUNT; CELL PROLIFERATION; CONTROLLED STUDY; DENTATE GYRUS; DRUG DOSE COMPARISON; DRUG EFFICACY; DRUG MECHANISM; ENZYME ACTIVATION; FORCED SWIMMING TEST; HIPPOCAMPUS; IMMOBILIZATION; MALE; MOUSE; NONHUMAN; PRIORITY JOURNAL; REPEATED DRUG DOSE; SIGNAL TRANSDUCTION;

ANALYSIS OF VARIANCE; ANIMALS; ANIMALS, NEWBORN; ANTIDEPRESSIVE AGENTS; BRAIN-DERIVED NEUROTROPHIC FACTOR; BROMODEOXYURIDINE; CELL PROLIFERATION; DIPEPTIDES; DOSE-RESPONSE RELATIONSHIP, DRUG; FREEZING REACTION, CATALEPTIC; GENE EXPRESSION REGULATION; HIPPOCAMPUS; MALE; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; ONCOGENE PROTEIN V-AKT; RNA, MESSENGER; SIGNAL TRANSDUCTION; SWIMMING; TIME FACTORS; TOR SERINE-THREONINE KINASES;

EID: 79953287961     PISSN: 01664328     EISSN: 18727549     Source Type: Journal    
DOI: 10.1016/j.bbr.2011.02.003     Document Type: Article

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