A novel single-chain-Fv antibody against connective tissue growth factor attenuates bleomycin-induced pulmonary fibrosis in mice

Respirology

Volumn 16, Issue 3, 2011, Pages 500-507

  Wang, Xihua ^a   Wu, Guoqiu ^b   Gou, Lixia ^b   Liu, Zhaozhao ^b   Wang, Xiyong ^b   Fan, Xiaobo ^c   Wu, Linyuan ^b   Liu, Naifeng ^b  

^a Respiratory Department   (China)

^b SOUTHEAST UNIVERSITY   (China)

^c CHINA PHARMACEUTICAL UNIVERSITY   (China)

Author keywords

Bleomycin; Connective tissue growth factor; Pulmonary fibrosis; Single chain variable fragment antibody

Indexed keywords

ALPHA SMOOTH MUSCLE ACTIN; BLEOMYCIN; CONNECTIVE TISSUE GROWTH FACTOR; CONNECTIVE TISSUE GROWTH FACTOR ANTIBODY; HYDROXYPROLINE; SINGLE CHAIN FRAGMENT VARIABLE ANTIBODY;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CELL TRANSDIFFERENTIATION; CONTROLLED STUDY; DISEASE SEVERITY; DRUG EFFECT; DRUG EFFICACY; EMBRYO; HISTOPATHOLOGY; HUMAN; HUMAN CELL; LEUKOCYTE COUNT; LEUKOCYTE DIFFERENTIAL COUNT; LUNG ALVEOLITIS; LUNG FIBROBLAST; LUNG FIBROSIS; LUNG LAVAGE; LUNG PARENCHYMA; MALE; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; TREATMENT OUTCOME; WESTERN BLOTTING;

ACTINS; ANIMALS; BLEOMYCIN; BRONCHOALVEOLAR LAVAGE FLUID; CONNECTIVE TISSUE GROWTH FACTOR; HYDROXYPROLINE; LEUKOCYTE COUNT; MALE; MICE; PULMONARY FIBROSIS; SEVERITY OF ILLNESS INDEX; SINGLE-CHAIN ANTIBODIES;

EID: 79953269645     PISSN: 13237799     EISSN: 14401843     Source Type: Journal    
DOI: 10.1111/j.1440-1843.2011.01938.x     Document Type: Article

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