-
1
-
-
0036074141
-
Lipopolysaccharides in liver injury: Molecular mechanisms of Kupffer cell activation
-
Su GL. Lipopolysaccharides in liver injury: molecular mechanisms of Kupffer cell activation. Am. J. Physiol. Gastrointest. Liver Physiol. 2002 283 : G256 65.
-
(2002)
Am. J. Physiol. Gastrointest. Liver Physiol.
, vol.283
-
-
Su, G.L.1
-
3
-
-
0034950477
-
Toll-like receptor 4 is involved in the mechanism of early alcohol-induced liver injury in mice
-
Uesugi T, Froh M, Arteel GE, Bradford BU, Thurman RG. Toll-like receptor 4 is involved in the mechanism of early alcohol-induced liver injury in mice. Hepatology 2001 34 : 101 8.
-
(2001)
Hepatology
, vol.34
, pp. 101-108
-
-
Uesugi, T.1
Froh, M.2
Arteel, G.E.3
Bradford, B.U.4
Thurman, R.G.5
-
4
-
-
0038185316
-
Toll-like receptor 4 mediates inflammatory signaling by bacterial lipopolysaccharide in human hepatic stellate cells
-
Paik YH, Schwabe RF, Bataller R, Russo MP, Jobin C, Brenner DA. Toll-like receptor 4 mediates inflammatory signaling by bacterial lipopolysaccharide in human hepatic stellate cells. Hepatology 2003 37 : 1043 55.
-
(2003)
Hepatology
, vol.37
, pp. 1043-1055
-
-
Paik, Y.H.1
Schwabe, R.F.2
Bataller, R.3
Russo, M.P.4
Jobin, C.5
Brenner, D.A.6
-
6
-
-
0034644472
-
TGFbeta signaling in growth control, cancer, and heritable disorders
-
Massague JB, Blain SW, Lo RS. TGFbeta signaling in growth control, cancer, and heritable disorders. Cell 2000 103 : 295 309.
-
(2000)
Cell
, vol.103
, pp. 295-309
-
-
Massague, J.B.1
Blain, S.W.2
Lo, R.S.3
-
7
-
-
0038682002
-
Mechanisms of TGF-beta signaling from cell membrane to the nucleus
-
Shi Y, Massague J. Mechanisms of TGF-beta signaling from cell membrane to the nucleus. Cell 2003 113 : 685 700.
-
(2003)
Cell
, vol.113
, pp. 685-700
-
-
Shi, Y.1
Massague, J.2
-
8
-
-
33646691720
-
Id1 is a critical mediator in TGF-beta-induced transdifferentiation of rat hepatic stellate cells
-
Wiercinska E, Wickert L, Denecke B et al. Id1 is a critical mediator in TGF-beta-induced transdifferentiation of rat hepatic stellate cells. Hepatology 2006 43 : 1032 41.
-
(2006)
Hepatology
, vol.43
, pp. 1032-1041
-
-
Wiercinska, E.1
Wickert, L.2
Denecke, B.3
-
9
-
-
34347235524
-
Reversible Smad-dependent signaling between tumor suppression and oncogenesis
-
Sekimoto G, Matsuzaki K, Yoshida K et al. Reversible Smad-dependent signaling between tumor suppression and oncogenesis. Cancer Res. 2007 67 : 5090 6.
-
(2007)
Cancer Res.
, vol.67
, pp. 5090-5096
-
-
Sekimoto, G.1
Matsuzaki, K.2
Yoshida, K.3
-
10
-
-
33744803766
-
Transforming growth factor-beta during carcinogenesis: The shift from epithelial to mesenchymal signaling
-
Matsuzaki K, Okazaki K. Transforming growth factor-beta during carcinogenesis: the shift from epithelial to mesenchymal signaling. J. Gastroenterol. 2006 41 : 295 303.
-
(2006)
J. Gastroenterol.
, vol.41
, pp. 295-303
-
-
Matsuzaki, K.1
Okazaki, K.2
-
11
-
-
33645576366
-
Smad3 phosphoisoform-mediated signaling during sporadic human colorectal carcinogenesis
-
Matsuzaki K. Smad3 phosphoisoform-mediated signaling during sporadic human colorectal carcinogenesis. Histol. Histopathol. 2006 21 : 645 62.
-
(2006)
Histol. Histopathol.
, vol.21
, pp. 645-662
-
-
Matsuzaki, K.1
-
12
-
-
0031587828
-
The MAD-related protein Smad7 associates with the TGFbeta receptor and functions as an antagonist of TGFbeta signaling
-
Hayashi H, Abdollah S, Qiu Y et al. The MAD-related protein Smad7 associates with the TGFbeta receptor and functions as an antagonist of TGFbeta signaling. Cell 1997 89 : 1165 73.
-
(1997)
Cell
, vol.89
, pp. 1165-1173
-
-
Hayashi, H.1
Abdollah, S.2
Qiu, Y.3
-
13
-
-
0030611757
-
Identification of Smad7, a TGF beta-inducible antagonist of TGF-beta signalling
-
Nakao A, Afrakhte M, Morén A et al. Identification of Smad7, a TGF beta-inducible antagonist of TGF-beta signalling. Nature 1997 389 (6651 631 5.
-
(1997)
Nature
, vol.389
, Issue.6651
, pp. 631-635
-
-
Nakao, A.1
Afrakhte, M.2
Morén, A.3
-
14
-
-
0033955048
-
Genomic locus and promoter region of rat Smad7, an important antagonist of TGFbeta signaling [in Process Citation]
-
Stopa M, Benes V, Ansorge W, Gressner AM, Dooley S. Genomic locus and promoter region of rat Smad7, an important antagonist of TGFbeta signaling [In Process Citation]. Mamm. Genome 2000 11 : 169 76.
-
(2000)
Mamm. Genome
, vol.11
, pp. 169-176
-
-
Stopa, M.1
Benes, V.2
Ansorge, W.3
Gressner, A.M.4
Dooley, S.5
-
15
-
-
24944497786
-
Non-Smad TGF-beta signals
-
Moustakas A, Heldin CH. Non-Smad TGF-beta signals. J. Cell Sci. 2005 118 : 3573 84.
-
(2005)
J. Cell Sci.
, vol.118
, pp. 3573-3584
-
-
Moustakas, A.1
Heldin, C.H.2
-
16
-
-
0029997830
-
Transdifferentiation of hepatic stellate cells (Ito cells) to myofibroblasts: A key event in hepatic fibrogenesis
-
Gressner AM. Transdifferentiation of hepatic stellate cells (Ito cells) to myofibroblasts: a key event in hepatic fibrogenesis. Kidney Int. 1996 49 : S39 S45.
-
(1996)
Kidney Int.
, vol.49
-
-
Gressner, A.M.1
-
17
-
-
32044437966
-
Anti-TGF-beta strategies for the treatment of chronic liver disease
-
Breitkopf K, Haas S, Wiercinska E, Singer MV, Dooley S. Anti-TGF-beta strategies for the treatment of chronic liver disease. Alcohol. Clin. Exp. Res. 2005 29 (11 Suppl. 121S 31S.
-
(2005)
Alcohol. Clin. Exp. Res.
, vol.29
, Issue.11 SUPPL.
-
-
Breitkopf, K.1
Haas, S.2
Wiercinska, E.3
Singer, M.V.4
Dooley, S.5
-
18
-
-
0035552143
-
Prediction of progressive liver fibrosis in hepatitis C infection by serum and tissue levels of transforming growth factor-beta
-
Kanzler S, Baumann M, Schirmacher P et al. Prediction of progressive liver fibrosis in hepatitis C infection by serum and tissue levels of transforming growth factor-beta. J. Viral Hepat. 2001 8 : 430 7.
-
(2001)
J. Viral Hepat.
, vol.8
, pp. 430-437
-
-
Kanzler, S.1
Baumann, M.2
Schirmacher, P.3
-
19
-
-
0038374866
-
Conditional tetracycline-regulated expression of TGF-beta1 in liver of transgenic mice leads to reversible intermediary fibrosis
-
Ueberham E, Loew R, Ueberham U, Schoenig K, Bujard H, Gebhardt R. Conditional tetracycline-regulated expression of TGF-beta1 in liver of transgenic mice leads to reversible intermediary fibrosis. Hepatology 2003 37 : 1067 78.
-
(2003)
Hepatology
, vol.37
, pp. 1067-1078
-
-
Ueberham, E.1
Loew, R.2
Ueberham, U.3
Schoenig, K.4
Bujard, H.5
Gebhardt, R.6
-
20
-
-
0033515099
-
Blockade of type beta transforming growth factor signaling prevents liver fibrosis and dysfunction in the rat
-
Qi Z, Atsuchi N, Ooshima A, Takeshita A, Ueno H. Blockade of type beta transforming growth factor signaling prevents liver fibrosis and dysfunction in the rat. Proc. Natl Acad. Sci. USA 1999 96 : 2345 9.
-
(1999)
Proc. Natl Acad. Sci. USA
, vol.96
, pp. 2345-2349
-
-
Qi, Z.1
Atsuchi, N.2
Ooshima, A.3
Takeshita, A.4
Ueno, H.5
-
21
-
-
0033984336
-
A soluble transforming growth factor beta receptor expressed in muscle prevents liver fibrogenesis and dysfunction in rats
-
Ueno H, Sakamoto T, Nakamura T et al. A soluble transforming growth factor beta receptor expressed in muscle prevents liver fibrogenesis and dysfunction in rats. Hum. Gene Ther. 2000 11 : 33 42.
-
(2000)
Hum. Gene Ther.
, vol.11
, pp. 33-42
-
-
Ueno, H.1
Sakamoto, T.2
Nakamura, T.3
-
22
-
-
0033607304
-
In vivo inhibition of rat stellate cell activation by soluble transforming growth factor beta type II receptor: A potential new therapy for hepatic fibrosis
-
George J, Roulot D, Koteliansky VE, Bissell DM. In vivo inhibition of rat stellate cell activation by soluble transforming growth factor beta type II receptor: a potential new therapy for hepatic fibrosis. Proc. Natl Acad. Sci. USA 1999 96 : 12719 24.
-
(1999)
Proc. Natl Acad. Sci. USA
, vol.96
, pp. 12719-12724
-
-
George, J.1
Roulot, D.2
Koteliansky, V.E.3
Bissell, D.M.4
-
23
-
-
0037716406
-
Smad7 prevents activation of hepatic stellate cells and liver fibrosis in rats
-
Dooley S, Hamzavi J, Breitkopf K et al. Smad7 prevents activation of hepatic stellate cells and liver fibrosis in rats. Gastroenterology 2003 125 : 178 91.
-
(2003)
Gastroenterology
, vol.125
, pp. 178-191
-
-
Dooley, S.1
Hamzavi, J.2
Breitkopf, K.3
-
24
-
-
0036136943
-
Mechanisms of TGF-beta-mediated apoptosis
-
Schuster N, Krieglstein K. Mechanisms of TGF-beta-mediated apoptosis. Cell Tissue Res. 2002 307 : 1 14.
-
(2002)
Cell Tissue Res.
, vol.307
, pp. 1-14
-
-
Schuster, N.1
Krieglstein, K.2
-
25
-
-
27744527762
-
Laminin-5 with transforming growth factor-beta1 induces epithelial to mesenchymal transition in hepatocellular carcinoma
-
Giannelli G, Bergamini C, Fransvea E, Sgarra C, Antonaci S. Laminin-5 with transforming growth factor-beta1 induces epithelial to mesenchymal transition in hepatocellular carcinoma. Gastroenterology 2005 129 : 1375 83.
-
(2005)
Gastroenterology
, vol.129
, pp. 1375-1383
-
-
Giannelli, G.1
Bergamini, C.2
Fransvea, E.3
Sgarra, C.4
Antonaci, S.5
-
26
-
-
33745107179
-
A crucial function of PDGF in TGF-beta-mediated cancer progression of hepatocytes
-
Gotzmann J, Fischer AN, Zojer M et al. A crucial function of PDGF in TGF-beta-mediated cancer progression of hepatocytes. Oncogene 2006 25 : 3170 85.
-
(2006)
Oncogene
, vol.25
, pp. 3170-3185
-
-
Gotzmann, J.1
Fischer, A.N.2
Zojer, M.3
-
27
-
-
0027164326
-
Growth inhibition by transforming growth factor-beta (TGF-beta) type I is restored in TGF-beta-resistant hepatoma cells after expression of TGF-beta receptor type II cDNA
-
Inagaki M, Moustakas A, Lin HY, Lodish HF, Carr BI. Growth inhibition by transforming growth factor-beta (TGF-beta) type I is restored in TGF-beta-resistant hepatoma cells after expression of TGF-beta receptor type II cDNA. Proc. Natl Acad. Sci. USA 1993 90 : 5359 63.
-
(1993)
Proc. Natl Acad. Sci. USA
, vol.90
, pp. 5359-5363
-
-
Inagaki, M.1
Moustakas, A.2
Lin, H.Y.3
Lodish, H.F.4
Carr, B.I.5
-
28
-
-
0034837309
-
Greater expression of transforming growth factor alpha and proliferating cell nuclear antigen staining in mouse hepatoblastomas than hepatocellular carcinomas induced by a diethylnitrosamine-sodium phenobarbital regimen
-
Sakairi T, Kobayashi K, Goto K et al. Greater expression of transforming growth factor alpha and proliferating cell nuclear antigen staining in mouse hepatoblastomas than hepatocellular carcinomas induced by a diethylnitrosamine- sodium phenobarbital regimen. Toxicol. Pathol. 2001 29 : 479 82.
-
(2001)
Toxicol. Pathol.
, vol.29
, pp. 479-482
-
-
Sakairi, T.1
Kobayashi, K.2
Goto, K.3
-
29
-
-
1642379154
-
The role of epithelial-to-mesenchymal transition in renal fibrosis
-
Zeisberg M, Kalluri R. The role of epithelial-to-mesenchymal transition in renal fibrosis. J. Mol. Med. 2004 82 : 175 81.
-
(2004)
J. Mol. Med.
, vol.82
, pp. 175-181
-
-
Zeisberg, M.1
Kalluri, R.2
-
30
-
-
0038717407
-
BMP-7 counteracts TGF-beta1-induced epithelial-to-mesenchymal transition and reverses chronic renal injury
-
Zeisberg M, Hanai J, Sugimoto H et al. BMP-7 counteracts TGF-beta1-induced epithelial-to-mesenchymal transition and reverses chronic renal injury. Nat. Med. 2003 9 : 964 8.
-
(2003)
Nat. Med.
, vol.9
, pp. 964-968
-
-
Zeisberg, M.1
Hanai, J.2
Sugimoto, H.3
-
31
-
-
0029763768
-
Interleukin-1 induction of type-1 plasminogen activator inhibitor (PAI-1) gene expression in the mouse hepatocyte line, AML 12
-
Seki T, Gelehrter T. Interleukin-1 induction of type-1 plasminogen activator inhibitor (PAI-1) gene expression in the mouse hepatocyte line, AML 12. J. Cell. Physiol. 1996 168 : 648 56.
-
(1996)
J. Cell. Physiol.
, vol.168
, pp. 648-656
-
-
Seki, T.1
Gelehrter, T.2
-
32
-
-
0026055366
-
Connective tissue growth factor: A cysteine-rich mitogen secreted by human vascular endothelial cells is related to the SRC-induced immediate early gene product CEF-10
-
Bradham DM, Igarashi A, Potter RL, Grotendorst GR. Connective tissue growth factor: a cysteine-rich mitogen secreted by human vascular endothelial cells is related to the SRC-induced immediate early gene product CEF-10. J. Cell Biol. 1991 114 : 1285 94.
-
(1991)
J. Cell Biol.
, vol.114
, pp. 1285-1294
-
-
Bradham, D.M.1
Igarashi, A.2
Potter, R.L.3
Grotendorst, G.R.4
-
33
-
-
1642452822
-
Insights into the molecular mechanism of chronic fibrosis: The role of connective tissue growth factor in scleroderma
-
Leask A, Denton CP, Abraham DJ. Insights into the molecular mechanism of chronic fibrosis: the role of connective tissue growth factor in scleroderma. J. Invest. Dermatol. 2004 122 : 1 6.
-
(2004)
J. Invest. Dermatol.
, vol.122
, pp. 1-6
-
-
Leask, A.1
Denton, C.P.2
Abraham, D.J.3
-
34
-
-
0031225015
-
Connective tissue growth factor: A mediator of TGF-beta action on fibroblasts
-
Grotendorst GR. Connective tissue growth factor: a mediator of TGF-beta action on fibroblasts. Cytokine Growth Factor Rev. 1997 8 : 171 9.
-
(1997)
Cytokine Growth Factor Rev.
, vol.8
, pp. 171-179
-
-
Grotendorst, G.R.1
-
35
-
-
0036281460
-
Effects and regulation of connective tissue growth factor on hepatic stellate cells
-
Paradis V, Dargere D, Bonvoust F, Vidaud M, Segarini P, Bedossa P. Effects and regulation of connective tissue growth factor on hepatic stellate cells. Lab. Invest. 2002 82 : 767 74.
-
(2002)
Lab. Invest.
, vol.82
, pp. 767-774
-
-
Paradis, V.1
Dargere, D.2
Bonvoust, F.3
Vidaud, M.4
Segarini, P.5
Bedossa, P.6
-
36
-
-
34548145815
-
Fibroblasts derive from hepatocytes in liver fibrosis via epithelial to mesenchymal transition
-
Zeisberg M, Yang C, Martino M et al. Fibroblasts derive from hepatocytes in liver fibrosis via epithelial to mesenchymal transition. J. Biol. Chem. 2007 282 : 23337 47.
-
(2007)
J. Biol. Chem.
, vol.282
, pp. 23337-23347
-
-
Zeisberg, M.1
Yang, C.2
Martino, M.3
-
37
-
-
34547599359
-
Transforming growth factor-beta1 induces an epithelial-to-mesenchymal transition state in mouse hepatocytes in vitro
-
89. 101.
-
Kaimori A, Potter J, Kaimori JY, Wang C, Mezey E, Koteish A. Transforming growth factor-beta1 induces an epithelial-to-mesenchymal transition state in mouse hepatocytes in vitro. J. Biol. Chem. 2007 282 : 22 89 101.
-
(2007)
J. Biol. Chem.
, vol.282
, pp. 22
-
-
Kaimori, A.1
Potter, J.2
Kaimori, J.Y.3
Wang, C.4
Mezey, E.5
Koteish, A.6
-
38
-
-
84895655497
-
Hepatocyte specific Smad7 expression attenuates TGF-βmediated fibrogenesis and protects against liver damage
-
Dooley S, Hamzavi J, Ciuclan L et al. Hepatocyte specific Smad7 expression attenuates TGF-βmediated fibrogenesis and protects against liver damage. Gastroenterology 2007 (in revision).
-
(2007)
Gastroenterology. (In Revision).
-
-
Dooley, S.1
Hamzavi, J.2
Ciuclan, L.3
|