Heat shock protein 104 inhibited the fibrillization of prion peptide 106-126 and disassembled prion peptide 106-126 fibrils in vitro

International Journal of Biochemistry and Cell Biology

Volumn 43, Issue 5, 2011, Pages 768-774

  Liu, Ying Hui ^a,b   Han, Yan Ling ^a,b   Song, Juan ^a,b   Wang, Ying ^a,b   Jing, Yuan Yuan ^a   Shi, Qi ^a   Tian, Chan ^a   Wang, Zhao Yun ^a   Li, Chao Ping ^b   Han, Jun ^a,c   Dong, Xiao Ping ^a  

^a CHINESE CENTER FOR DISEASE CONTROL AND PREVENTION   (China)

^b ANHUI UNIVERSITY OF SCIENCE AND TECHNOLOGY   (China)

^c NONE   (China)

Author keywords

Cytotoxicity; Fibril; Hsp104; Prion disease; PrP106 126

Indexed keywords

HEAT SHOCK PROTEIN 104; PRION PROTEIN; PRION PROTEIN 106-126; RECOMBINANT PROTEIN; UNCLASSIFIED DRUG;

ARTICLE; BETA SHEET; CELL VIABILITY; CIRCULAR DICHROISM; CONTROLLED STUDY; HUMAN; HUMAN CELL; INCUBATION TIME; NEUROTOXICITY; NITROBLUE TETRAZOLIUM TEST; PROTEIN AGGREGATION; PROTEIN ASSEMBLY; PROTEIN PROTEIN INTERACTION; PROTEIN SECONDARY STRUCTURE;

AMINO ACID SEQUENCE; CELL LINE, TUMOR; FUNGAL PROTEINS; HEAT-SHOCK PROTEINS; HUMANS; MOLECULAR SEQUENCE DATA; PEPTIDE FRAGMENTS; PRIONS; PROTEIN MULTIMERIZATION; PROTEIN STRUCTURE, SECONDARY; PROTEIN UNFOLDING;

EID: 79953214343     PISSN: 13572725     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.biocel.2011.01.022     Document Type: Article

References (30)

1. A.P. Ben-Zvi, J. Chatellier, A.R. Fersht, and P. Goloubinoff Minimal and optimal mechanisms for GroE-mediated protein folding Proc Natl Acad Sci USA 95 1998 15275 15280 (Pubitemid 29018689)
2. A.L. Bergström, H. Cordes, N. Zsurger, P.M. Heegaard, H. Laursen, and J. Chabry Amidation and structure relaxation abolish the neurotoxicity of the prion peptide PrP106-126 in vivo and in vitro J Biol Chem 280 2005 23114 23121 (Pubitemid 40853222)
3. B. Caughey, and P.T. Lansbury Protofibrils, pores, fibrils, and neurodegeneration: reparating the responsible protein aggregates from the innocent bystanders Annu Rev Neurosci 26 2003 267 298 (Pubitemid 37064935)
4. J. Chatellier, F. Hill, P.A. Lund, and A.R. Fersht In vivo activities of GroEL minichaperones Proc Natl Acad Sci USA 95 1998 9861 9866 (Pubitemid 28415260)
5. I.H. Cheng, K. Scearce-Levie, J. Legleiter, J.J. Palop, H. Gerstein, and N. Bien-Ly Enhancing the fibrillization and deposition of the amyloid-b peptide reduces its negative impact on behavior and synaptic activity-dependent proteins J Biol Chem 282 2007 23818 23828
6. Y.O. Chernoff, S.L. Lindquist, B. Ono, S.G. Inge-Vechtomov, and S.W. Liebman Role of the chaperone protein Hsp104 in propagation of the yeast prion-like factor [P SI+] Science 268 1995 880 884
7. J. Ciesielski-Treska, N.J. Grant, G. Ulrich, M. Corrotte, Y. Bailly, and A.M. Haeberle Fibrillar prion peptide (106-126) and scrapie prion protein hamper phagocytosis in microglia Glia 46 2004 101 115 (Pubitemid 38596177)
8. F. Dandoy-Dron, A. Bogdanova, V. Beringue, Y. Bailly, M.G. Tovey, and H. Laude Infection by ME7 prion is not modified in transgenic mice expressing the yeast chaperone Hsp104 in neurons Neurosci Lett 405 2006 181 185 (Pubitemid 44209305)
9. S.M. Doyle, and S. Wickner Hsp104 and ClpB: protein disaggregating machines Trends Biochem Sci 34 2009 40 48
10. S.M. Doyle, J. Shorter, M. Zolkiewski, J.R. Hoskins, S. Lindquist, and S. Wickner Asymmetric deceleration of ClpB or Hsp104 ATPase activity unleashes protein-remodeling activity Nat Struct Mol Biol 14 2007 114 122
11. S.M. Doyle, J.R. Hoskins, and S. Wickner Collaboration between the ClpB AAA+ remodeling protein and the DnaK chaperone system Proc Natl Acad Sci USA 104 2007 11138 11144 (Pubitemid 47175107)
12. J.R. Glover, and S. Lindquist Hsp104, Hsp70, and Hsp40: a novel chaperone system that rescues previously aggregated proteins Cell 94 1998 73 82 (Pubitemid 28347471)
13. J. Gong, A. Jellali, V. Forster, J. Mutterer, E. Dubus, and W.D. Altrock The toxicity of the PrP106-126 prion peptide on cultured photoreceptors correlates with the prion protein distribution in the mammalian and human retina Am J Pathol 170 2007 1314 1324 (Pubitemid 47339338)
14. M. Grabenauer, C. Wu, P. Soto, J.E. Shea, and M.T. Bowers Oligomers of the prion protein fragment 106-126 are likely assembled from β-hairpins in solution, and methionine oxidation inhibits assembly without altering the peptide's monomeric conformation J Am Chem Soc 132 2010 532 539
15. R.S. Hegde, J.A. Mastrianni, M.R. Scott, K.A. DeFea, P. Tremblay, and M. Torchia Transmembrane form of the prion protein in neurodegenerative disease Science 279 1998 827 834 (Pubitemid 28106269)
16. C. Hetz, M. Russelakis-Carneiro, S. Wälchli, S. Carboni, E. Vial-Knecht, and K. Maundrell The disulfide isomerase Grp58 is a protective factor against prion neurotoxicity J Neurosci 25 2005 2793 2802 (Pubitemid 40389237)
17. Y. Inoue Life cycle of yeast prions: propagation mediated by amyloid fibrils Protein Pept Lett 16 2009 271 276
18. T. Jin, Y. Gu, G. Zanusso, M. Sy, A. Kumar, and M. Cohen N. Singh The chaperone protein BiP binds to a mutant prion protein and mediates its degradation by the proteasome J Biol Chem 275 2000 38699 38704 (Pubitemid 32009203)
19. C. Lo Bianco, J. Shorter, E. Régulier, H. Lashuel, T. Iwatsubo, and S. Lindquist Hsp104 antagonizes α-synuclein aggregation and reduces dopaminergic degeneration in a rat model of Parkinson disease J Clin Invest 118 2008 3087 3097
20. X. Lu, P.L. Wintrode, and W.K. Surewicz Beta-sheet core of human prion protein amyloid fibrils as determined by hydrogen/deuterium exchange Proc Natl Acad Sci USA 104 2007 1510 1515 (Pubitemid 46214621)
21. H. Moriyama, H.K. Edskes, and R.B. Wickner [URE3] prion propagation in Saccharomyces cerevisiae: requirement for chaperone Hsp104 and curing by overexpressed chaperone Ydj1p Mol Cell Biol 20 2000 8916 8922 (Pubitemid 32245922)
22. P.J. Muchowski Protein Misfolding, Amyloid Formation, and Neurodegeneration Neuron 35 2002 9 12
23. Prusiner S. Proins B. Proc Natl Acad Sci USA 1998; 95:13363-13383.
24. J. Shorter Hsp104: a weapon to combat diverse neurodegenerative disorders Neurosignals 16 2008 63 74 (Pubitemid 350308322)
25. J. Shorter, and S. Lindquist Hsp104 catalyzes formation and elimination of self-replicating Sup35 prion conformers Science 304 2004 1793 1797 (Pubitemid 38787894)
26. J. Shorter, and S. Lindquist Destruction or potentiation of different prions catalyzed by similar Hsp104 remodeling activities Mol Cell 23 2006 425 438 (Pubitemid 44128844)
27. M. Stefani Structural polymorphism of amyloid oligomers and fibrils underlies different fibrillization pathways: immunogenicity and cytotoxicity Curr Protein Pept Sci 11 2010 343 354
28. J. Tatzelt, S.B. Prusiner, and W.J. Welch Chemical chaperones interfere with the formation of scrapie prion protein EMBO J 15 1996 6363 6373 (Pubitemid 26413769)
29. P. Walsh, J. Yau, K. Simonetti, and S. Sharpe Morphology and secondary structure of stable beta-oligomers formed by amyloid peptide PrP(106-126) Biochemistry 48 2009 5779 5781
30. R. Zahn, A.M. Buckle, S. Perrett, C.M. Johnson, F.J. Corrales, and R. Golbik Chaperone activity and structure of monomeric polypeptide binding domains of GroEL Proc Natl Acad Sci USA 93 1996 15024 15029 (Pubitemid 27009545)