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Volumn 140, Issue 4, 2011, Pages 1143-1146

Timing Is everything: Brca2 and p53 mutations in pancreatic cancer

Author keywords

[No Author keywords available]

Indexed keywords

BRCA2 PROTEIN; DNA; GEMCITABINE; NICOTINAMIDE ADENINE DINUCLEOTIDE ADENOSINE DIPHOSPHATE RIBOSYLTRANSFERASE INHIBITOR; PROTEIN P53;

EID: 79953213660     PISSN: 00165085     EISSN: None     Source Type: Journal    
DOI: 10.1053/j.gastro.2011.02.026     Document Type: Editorial
Times cited : (5)

References (22)
  • 1
    • 0033523268 scopus 로고    scopus 로고
    • Cancer risks in BRCA2 mutation carriers
    • The Breast Cancer Linkage Consortium
    • The Breast Cancer Linkage Consortium Cancer risks in BRCA2 mutation carriers J Natl Cancer Inst 91 1999 1310 1316
    • (1999) J Natl Cancer Inst , vol.91 , pp. 1310-1316
  • 6
    • 67650471685 scopus 로고    scopus 로고
    • Inhibition of poly(ADP-ribose) polymerase in tumors from BRCA mutation carriers
    • P.C. Fong, D.S. Boss, and T.A. Yap Inhibition of poly(ADP-ribose) polymerase in tumors from BRCA mutation carriers N Engl J Med 361 2009 123 134
    • (2009) N Engl J Med , vol.361 , pp. 123-134
    • Fong, P.C.1    Boss, D.S.2    Yap, T.A.3
  • 7
    • 77954032829 scopus 로고    scopus 로고
    • Poly(ADP)-ribose polymerase inhibition: Frequent durable responses in BRCA carrier ovarian cancer correlating with platinum-free interval
    • P.C. Fong, T.A. Yap, and D.S. Boss Poly(ADP)-ribose polymerase inhibition: frequent durable responses in BRCA carrier ovarian cancer correlating with platinum-free interval J Clin Oncol 28 2010 2512 2519
    • (2010) J Clin Oncol , vol.28 , pp. 2512-2519
    • Fong, P.C.1    Yap, T.A.2    Boss, D.S.3
  • 8
    • 79952126923 scopus 로고    scopus 로고
    • Therapeutic potential of poly(ADP-ribose) polymerase inhibitor AG014699 in human cancers with mutated or methylated BRCA1 or BRCA2
    • Y. Drew, E.A. Mulligan, and W.T. Vong Therapeutic potential of poly(ADP-ribose) polymerase inhibitor AG014699 in human cancers with mutated or methylated BRCA1 or BRCA2 J Natl Cancer Inst 2010 Dec 23 [Epub ahead of print]
    • (2010) J Natl Cancer Inst
    • Drew, Y.1    Mulligan, E.A.2    Vong, W.T.3
  • 10
    • 79953181635 scopus 로고    scopus 로고
    • Inactivation of Brca2 promotes Trp53-associated but inhibits KrasG12D-dependent pancreatic cancer development in mice
    • M. Rowley, A. Ohashi, and G. Mondal Inactivation of Brca2 promotes Trp53-associated but inhibits KrasG12D-dependent pancreatic cancer development in mice Gastroenterology 140 2011 1303 1313
    • (2011) Gastroenterology , vol.140 , pp. 1303-1313
    • Rowley, M.1    Ohashi, A.2    Mondal, G.3
  • 11
    • 18844431062 scopus 로고    scopus 로고
    • Pancreatic cancer: Basic and clinical aspects
    • DOI 10.1053/j.gastro.2005.04.001, PII S0016508505006323
    • G. Schneider, J.T. Siveke, and F. Eckel Pancreatic cancer: basic and clinical aspects Gastroenterology 128 2005 1606 1625 (Pubitemid 40692555)
    • (2005) Gastroenterology , vol.128 , Issue.6 , pp. 1606-1625
    • Schneider, G.1    Siveke, J.T.2    Eckel, F.3    Schmid, R.M.4
  • 12
    • 0024292722 scopus 로고
    • Most human carcinomas of the exocrine pancreas contain mutant c-K-ras genes
    • C. Almoguera, D. Shibata, and K. Forrester Most human carcinomas of the exocrine pancreas contain mutant c-K-ras genes Cell 53 1988 549 554
    • (1988) Cell , vol.53 , pp. 549-554
    • Almoguera, C.1    Shibata, D.2    Forrester, K.3
  • 13
    • 77955488036 scopus 로고    scopus 로고
    • LKB1 haploinsufficiency cooperates with Kras to promote pancreatic cancer through suppression of p21-dependent growth arrest
    • J.P. Morton, N.B. Jamieson, and S.A. Karim LKB1 haploinsufficiency cooperates with Kras to promote pancreatic cancer through suppression of p21-dependent growth arrest Gastroenterology 139 2010 586 597
    • (2010) Gastroenterology , vol.139 , pp. 586-597
    • Morton, J.P.1    Jamieson, N.B.2    Karim, S.A.3
  • 14
    • 77957353339 scopus 로고    scopus 로고
    • Hereditary pancreatic cancer
    • S. Grover, and S. Syngal Hereditary pancreatic cancer Gastroenterology 139 2010 1076 1080
    • (2010) Gastroenterology , vol.139 , pp. 1076-1080
    • Grover, S.1    Syngal, S.2
  • 15
    • 53049110158 scopus 로고    scopus 로고
    • Stabilization of beta-catenin induces pancreas tumor formation
    • P.W. Heiser, D.A. Cano, and L. Landsman Stabilization of beta-catenin induces pancreas tumor formation Gastroenterology 135 2008 1288 1300
    • (2008) Gastroenterology , vol.135 , pp. 1288-1300
    • Heiser, P.W.1    Cano, D.A.2    Landsman, L.3
  • 17
    • 0035734285 scopus 로고    scopus 로고
    • Synergistic tumor suppressor activity of BRCA2 and p53 in a conditional mouse model for breast cancer
    • DOI 10.1038/ng747
    • J. Jonkers, R. Meuwissen, and H. van der Gulden Synergistic tumor suppressor activity of BRCA2 and p53 in a conditional mouse model for breast cancer Nat Genet 29 2001 418 425 (Pubitemid 34326692)
    • (2001) Nature Genetics , vol.29 , Issue.4 , pp. 418-425
    • Jonkers, J.1    Meuwissen, R.2    Van Der Gulden, H.3    Peterse, H.4    Van Der Valk, M.5    Berns, A.6
  • 18
    • 78249247414 scopus 로고    scopus 로고
    • Germline Brca2 heterozygosity promotes Kras(G12D)-driven carcinogenesis in a murine model of familial pancreatic cancer
    • F. Skoulidis, L.D. Cassidy, and V. Pisupati Germline Brca2 heterozygosity promotes Kras(G12D)-driven carcinogenesis in a murine model of familial pancreatic cancer Cancer Cell 18 2010 499 509
    • (2010) Cancer Cell , vol.18 , pp. 499-509
    • Skoulidis, F.1    Cassidy, L.D.2    Pisupati, V.3
  • 19
    • 78751610848 scopus 로고    scopus 로고
    • Iniparib plus chemotherapy in metastatic triple-negative breast cancer
    • J. O'Shaughnessy, C. Osborne, and J.E. Pippen Iniparib plus chemotherapy in metastatic triple-negative breast cancer N Engl J Med 364 2011 205 214
    • (2011) N Engl J Med , vol.364 , pp. 205-214
    • O'Shaughnessy, J.1    Osborne, C.2    Pippen, J.E.3
  • 20
    • 67149143399 scopus 로고    scopus 로고
    • Inhibition of Hedgehog signaling enhances delivery of chemotherapy in a mouse model of pancreatic cancer
    • K.P. Olive, M.A. Jacobetz, and C.J. Davidson Inhibition of Hedgehog signaling enhances delivery of chemotherapy in a mouse model of pancreatic cancer Science 324 2009 1457 1461
    • (2009) Science , vol.324 , pp. 1457-1461
    • Olive, K.P.1    Jacobetz, M.A.2    Davidson, C.J.3
  • 21
    • 77953898050 scopus 로고    scopus 로고
    • Dasatinib inhibits the development of metastases in a mouse model of pancreatic ductal adenocarcinoma
    • J.P. Morton, S.A. Karim, and K. Graham Dasatinib inhibits the development of metastases in a mouse model of pancreatic ductal adenocarcinoma Gastroenterology 139 2010 292 303
    • (2010) Gastroenterology , vol.139 , pp. 292-303
    • Morton, J.P.1    Karim, S.A.2    Graham, K.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.