-
1
-
-
0033523268
-
Cancer risks in BRCA2 mutation carriers
-
The Breast Cancer Linkage Consortium
-
The Breast Cancer Linkage Consortium Cancer risks in BRCA2 mutation carriers J Natl Cancer Inst 91 1999 1310 1316
-
(1999)
J Natl Cancer Inst
, vol.91
, pp. 1310-1316
-
-
-
2
-
-
0036644884
-
Evaluation of candidate genes MAP2K4, MADH4, ACVR1B, and BRCA2 in familial pancreatic cancer: Deleterious BRCA2 mutations in 17%
-
K.M. Murphy, K.A. Brune, and C. Griffin Evaluation of candidate genes MAP2K4, MADH4, ACVR1B, and BRCA2 in familial pancreatic cancer: deleterious BRCA2 mutations in 17% Cancer Res 62 2002 3789 3793 (Pubitemid 34728862)
-
(2002)
Cancer Research
, vol.62
, Issue.13
, pp. 3789-3793
-
-
Murphy, K.M.1
Brune, K.A.2
Griffin, C.3
Sollenberger, J.E.4
Petersen, G.M.5
Bansal, R.6
Hruban, R.H.7
Kern, S.E.8
-
4
-
-
0037420026
-
BRCA2 germline mutations in familial pancreatic carcinoma
-
S.A. Hahn, B. Greenhalf, and I. Ellis BRCA2 germline mutations in familial pancreatic carcinoma J Natl Cancer Inst 95 2003 214 221 (Pubitemid 36240634)
-
(2003)
Journal of the National Cancer Institute
, vol.95
, Issue.3
, pp. 214-221
-
-
Hahn, S.A.1
Greenhalf, B.2
Ellis, I.3
Sina-Frey, M.4
Rieder, H.5
Korte, B.6
Gerdes, B.7
Kress, R.8
Ziegler, A.9
Raeburn, J.A.10
Campra, D.11
Grutzmann, R.12
Rehder, H.13
Rothmund, M.14
Schmiegel, W.15
Neoptolemos, J.P.16
Bartsch, D.K.17
-
6
-
-
67650471685
-
Inhibition of poly(ADP-ribose) polymerase in tumors from BRCA mutation carriers
-
P.C. Fong, D.S. Boss, and T.A. Yap Inhibition of poly(ADP-ribose) polymerase in tumors from BRCA mutation carriers N Engl J Med 361 2009 123 134
-
(2009)
N Engl J Med
, vol.361
, pp. 123-134
-
-
Fong, P.C.1
Boss, D.S.2
Yap, T.A.3
-
7
-
-
77954032829
-
Poly(ADP)-ribose polymerase inhibition: Frequent durable responses in BRCA carrier ovarian cancer correlating with platinum-free interval
-
P.C. Fong, T.A. Yap, and D.S. Boss Poly(ADP)-ribose polymerase inhibition: frequent durable responses in BRCA carrier ovarian cancer correlating with platinum-free interval J Clin Oncol 28 2010 2512 2519
-
(2010)
J Clin Oncol
, vol.28
, pp. 2512-2519
-
-
Fong, P.C.1
Yap, T.A.2
Boss, D.S.3
-
8
-
-
79952126923
-
Therapeutic potential of poly(ADP-ribose) polymerase inhibitor AG014699 in human cancers with mutated or methylated BRCA1 or BRCA2
-
Y. Drew, E.A. Mulligan, and W.T. Vong Therapeutic potential of poly(ADP-ribose) polymerase inhibitor AG014699 in human cancers with mutated or methylated BRCA1 or BRCA2 J Natl Cancer Inst 2010 Dec 23 [Epub ahead of print]
-
(2010)
J Natl Cancer Inst
-
-
Drew, Y.1
Mulligan, E.A.2
Vong, W.T.3
-
9
-
-
17244375049
-
Specific killing of BRCA2-deficient tumours with inhibitors of poly(ADP-ribose) polymerase
-
DOI 10.1038/nature03443
-
H.E. Bryant, N. Schultz, and H.D. Thomas Specific killing of BRCA2-deficient tumours with inhibitors of poly(ADP-ribose) polymerase Nature 434 2005 913 917 (Pubitemid 40559005)
-
(2005)
Nature
, vol.434
, Issue.7035
, pp. 913-917
-
-
Bryant, H.E.1
Schultz, N.2
Thomas, H.D.3
Parker, K.M.4
Flower, D.5
Lopez, E.6
Kyle, S.7
Meuth, M.8
Curtin, N.J.9
Helleday, T.10
-
10
-
-
79953181635
-
Inactivation of Brca2 promotes Trp53-associated but inhibits KrasG12D-dependent pancreatic cancer development in mice
-
M. Rowley, A. Ohashi, and G. Mondal Inactivation of Brca2 promotes Trp53-associated but inhibits KrasG12D-dependent pancreatic cancer development in mice Gastroenterology 140 2011 1303 1313
-
(2011)
Gastroenterology
, vol.140
, pp. 1303-1313
-
-
Rowley, M.1
Ohashi, A.2
Mondal, G.3
-
11
-
-
18844431062
-
Pancreatic cancer: Basic and clinical aspects
-
DOI 10.1053/j.gastro.2005.04.001, PII S0016508505006323
-
G. Schneider, J.T. Siveke, and F. Eckel Pancreatic cancer: basic and clinical aspects Gastroenterology 128 2005 1606 1625 (Pubitemid 40692555)
-
(2005)
Gastroenterology
, vol.128
, Issue.6
, pp. 1606-1625
-
-
Schneider, G.1
Siveke, J.T.2
Eckel, F.3
Schmid, R.M.4
-
12
-
-
0024292722
-
Most human carcinomas of the exocrine pancreas contain mutant c-K-ras genes
-
C. Almoguera, D. Shibata, and K. Forrester Most human carcinomas of the exocrine pancreas contain mutant c-K-ras genes Cell 53 1988 549 554
-
(1988)
Cell
, vol.53
, pp. 549-554
-
-
Almoguera, C.1
Shibata, D.2
Forrester, K.3
-
13
-
-
77955488036
-
LKB1 haploinsufficiency cooperates with Kras to promote pancreatic cancer through suppression of p21-dependent growth arrest
-
J.P. Morton, N.B. Jamieson, and S.A. Karim LKB1 haploinsufficiency cooperates with Kras to promote pancreatic cancer through suppression of p21-dependent growth arrest Gastroenterology 139 2010 586 597
-
(2010)
Gastroenterology
, vol.139
, pp. 586-597
-
-
Morton, J.P.1
Jamieson, N.B.2
Karim, S.A.3
-
14
-
-
77957353339
-
Hereditary pancreatic cancer
-
S. Grover, and S. Syngal Hereditary pancreatic cancer Gastroenterology 139 2010 1076 1080
-
(2010)
Gastroenterology
, vol.139
, pp. 1076-1080
-
-
Grover, S.1
Syngal, S.2
-
15
-
-
53049110158
-
Stabilization of beta-catenin induces pancreas tumor formation
-
P.W. Heiser, D.A. Cano, and L. Landsman Stabilization of beta-catenin induces pancreas tumor formation Gastroenterology 135 2008 1288 1300
-
(2008)
Gastroenterology
, vol.135
, pp. 1288-1300
-
-
Heiser, P.W.1
Cano, D.A.2
Landsman, L.3
-
16
-
-
7844247959
-
P53 mutation with frequent novel codons but not a mutator phenotype in BRCA1- and BRCA2-associated breast tumours
-
T. Crook, L.A. Brooks, and S. Crossland p53 mutation with frequent novel condons but not a mutator phenotype in BRCA1- and BRCA2-associated breast tumours Oncogene 17 1998 1681 1689 (Pubitemid 28482645)
-
(1998)
Oncogene
, vol.17
, Issue.13
, pp. 1681-1689
-
-
Crook, T.1
Brooks, L.A.2
Crossland, S.3
Osin, P.4
Barker, K.T.5
Waller, J.6
Philp, E.7
Smith, P.D.8
Yulug, I.9
Peto, J.10
Parker, G.11
Allday, M.J.12
Crompton, M.R.13
Gusterson, B.A.14
-
17
-
-
0035734285
-
Synergistic tumor suppressor activity of BRCA2 and p53 in a conditional mouse model for breast cancer
-
DOI 10.1038/ng747
-
J. Jonkers, R. Meuwissen, and H. van der Gulden Synergistic tumor suppressor activity of BRCA2 and p53 in a conditional mouse model for breast cancer Nat Genet 29 2001 418 425 (Pubitemid 34326692)
-
(2001)
Nature Genetics
, vol.29
, Issue.4
, pp. 418-425
-
-
Jonkers, J.1
Meuwissen, R.2
Van Der Gulden, H.3
Peterse, H.4
Van Der Valk, M.5
Berns, A.6
-
18
-
-
78249247414
-
Germline Brca2 heterozygosity promotes Kras(G12D)-driven carcinogenesis in a murine model of familial pancreatic cancer
-
F. Skoulidis, L.D. Cassidy, and V. Pisupati Germline Brca2 heterozygosity promotes Kras(G12D)-driven carcinogenesis in a murine model of familial pancreatic cancer Cancer Cell 18 2010 499 509
-
(2010)
Cancer Cell
, vol.18
, pp. 499-509
-
-
Skoulidis, F.1
Cassidy, L.D.2
Pisupati, V.3
-
19
-
-
78751610848
-
Iniparib plus chemotherapy in metastatic triple-negative breast cancer
-
J. O'Shaughnessy, C. Osborne, and J.E. Pippen Iniparib plus chemotherapy in metastatic triple-negative breast cancer N Engl J Med 364 2011 205 214
-
(2011)
N Engl J Med
, vol.364
, pp. 205-214
-
-
O'Shaughnessy, J.1
Osborne, C.2
Pippen, J.E.3
-
20
-
-
67149143399
-
Inhibition of Hedgehog signaling enhances delivery of chemotherapy in a mouse model of pancreatic cancer
-
K.P. Olive, M.A. Jacobetz, and C.J. Davidson Inhibition of Hedgehog signaling enhances delivery of chemotherapy in a mouse model of pancreatic cancer Science 324 2009 1457 1461
-
(2009)
Science
, vol.324
, pp. 1457-1461
-
-
Olive, K.P.1
Jacobetz, M.A.2
Davidson, C.J.3
-
21
-
-
77953898050
-
Dasatinib inhibits the development of metastases in a mouse model of pancreatic ductal adenocarcinoma
-
J.P. Morton, S.A. Karim, and K. Graham Dasatinib inhibits the development of metastases in a mouse model of pancreatic ductal adenocarcinoma Gastroenterology 139 2010 292 303
-
(2010)
Gastroenterology
, vol.139
, pp. 292-303
-
-
Morton, J.P.1
Karim, S.A.2
Graham, K.3
-
22
-
-
43249121177
-
Stromal gene expression predicts clinical outcome in breast cancer
-
DOI 10.1038/nm1764, PII NM1764
-
G. Finak, N. Bertos, and F. Pepin Stromal gene expression predicts clinical outcome in breast cancer Nat Med 14 2008 518 527 (Pubitemid 351655218)
-
(2008)
Nature Medicine
, vol.14
, Issue.5
, pp. 518-527
-
-
Finak, G.1
Bertos, N.2
Pepin, F.3
Sadekova, S.4
Souleimanova, M.5
Zhao, H.6
Chen, H.7
Omeroglu, G.8
Meterissian, S.9
Omeroglu, A.10
Hallett, M.11
Park, M.12
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