SCOPUS 정보 검색 플랫폼

Volumn 9, Issue 8, 2011, Pages 2925-2937

Soluble polymer supported divergent synthesis of tetracyclic benzene-fused pyrazino/diazepino indoles: An advanced synthetic approach to bioactive scaffolds

(4) Lin, Po Tsung a Salunke, Deepak B a Chen, Li Hsun a Sun, Chung Ming a

a NATIONAL CHIAO TUNG UNIVERSITY (Taiwan)

Author keywords

[No Author keywords available]

Indexed keywords

BIOACTIVE SCAFFOLD; DIVERGENT SYNTHESIS; HETEROCYCLIC MOLECULES; IMMUNOSORBANT ASSAY; IN-VITRO; KINASE RECEPTORS; POTENTIAL DRUG; RATE ACCELERATION; SOLUBLE POLYMERS; SYNTHETIC APPROACH; VASCULAR ENDOTHELIAL GROWTH FACTOR RECEPTOR;

BENZENE; ENZYMES; MICROWAVE IRRADIATION; SCAFFOLDS;

CONDENSATION REACTIONS;

AZEPINE DERIVATIVE; BENZENE; FUSED HETEROCYCLIC RINGS; INDOLE DERIVATIVE; MACROGOL DERIVATIVE; PROTEIN KINASE INHIBITOR; PYRAZINE DERIVATIVE; VASCULOTROPIN RECEPTOR 3;

ARTICLE; CHEMICAL STRUCTURE; CHEMISTRY; DRUG ANTAGONISM; SOLUBILITY; STRUCTURE ACTIVITY RELATION; SYNTHESIS;

AZEPINES; BENZENE; HETEROCYCLIC COMPOUNDS WITH 4 OR MORE RINGS; INDOLES; MODELS, MOLECULAR; MOLECULAR STRUCTURE; POLYETHYLENE GLYCOLS; PROTEIN KINASE INHIBITORS; PYRAZINES; SOLUBILITY; STRUCTURE-ACTIVITY RELATIONSHIP; VASCULAR ENDOTHELIAL GROWTH FACTOR RECEPTOR-3;

EID: 79953208292 PISSN: 14770520 EISSN: None Source Type: Journal
DOI: 10.1039/c0ob01126f Document Type: Article

Times cited : (24)

References (49)

1
- 35448950092
- A. A. Patchett R. P. Nargund Annu. Rep. Med. Chem. 2000 35 289 298
- (2000) Annu. Rep. Med. Chem. , vol.35 , pp. 289-298
- Patchett, A.A.¹ Nargund, R.P.²

2
- 45249123879
- A. H. Lipkus Q. Yuan K. A. Lucas S. A. Funk W. F. Bartelt III R. J. Schenck A. J. Trippe J. Org. Chem. 2008 73 4443 4451
- (2008) J. Org. Chem. , vol.73 , pp. 4443-4451
- Lipkus, A.H.¹ Yuan, Q.² Lucas, K.A.³ Funk, S.A.⁴ Bartelt Iii, W.F.⁵ Schenck, R.J.⁶ Trippe, A.J.⁷

3
- 64949112806
- C. Gil S. Brase J. Comb. Chem. 2009 11 175 197
- (2009) J. Comb. Chem. , vol.11 , pp. 175-197
- Gil, C.¹ Brase, S.²

4
- 68849110176
- F. R. de Sa Alves E. J. Barreiro C. A. M. Fraga Mini-Rev. Med. Chem. 2009 9 782 793
- (2009) Mini-Rev. Med. Chem. , vol.9 , pp. 782-793
- De Sa Alves, F.R.¹ Barreiro, E.J.² Fraga, C.A.M.³

5
- 0037366605
- D. A. Horton G. T. Bourne M. L. Smythe Chem. Rev. 2003 103 893 930
- (2003) Chem. Rev. , vol.103 , pp. 893-930
- Horton, D.A.¹ Bourne, G.T.² Smythe, M.L.³

6
- 67649337286
- N. R. Candeias L. C. Branco P. M. Gois C. A. M. Afonso A. F. Trindade Chem. Rev. 2009 109 2703 2802
- (2009) Chem. Rev. , vol.109 , pp. 2703-2802
- Candeias, N.R.¹ Branco, L.C.² Gois, P.M.³ Afonso, C.A.M.⁴ Trindade, A.F.⁵

7
- 70349784870
- K. Kumar H. Waldmann Angew. Chem., Int. Ed. 2009 48 3224 3242
- (2009) Angew. Chem., Int. Ed. , vol.48 , pp. 3224-3242
- Kumar, K.¹ Waldmann, H.²

8
- 0141427680
- L. F. Tietze H. P. Bell S. Chandrasekhar Angew. Chem., Int. Ed. 2003 42 3996 4028
- (2003) Angew. Chem., Int. Ed. , vol.42 , pp. 3996-4028
- Tietze, L.F.¹ Bell, H.P.² Chandrasekhar, S.³

9
- 70350749437
- T. E. Nielsen M. Meldal Curr. Opin. Drug Discovery Dev. 2009 12 798 810
- (2009) Curr. Opin. Drug Discovery Dev. , vol.12 , pp. 798-810
- Nielsen, T.E.¹ Meldal, M.²

10
- 45149106841
- J. P. Kennedy L. Williams T. M. Bridges R. N. Daniels D. Weaver C. W. Lindsley J. Comb. Chem. 2008 10 345 354
- (2008) J. Comb. Chem. , vol.10 , pp. 345-354
- Kennedy, J.P.¹ Williams, L.² Bridges, T.M.³ Daniels, R.N.⁴ Weaver, D.⁵ Lindsley, C.W.⁶

11
- 0034193924
- R. N. Lawrence Drug Discovery Today 2000 5 172 175
- (2000) Drug Discovery Today , vol.5 , pp. 172-175
- Lawrence, R.N.¹

12
- 84890597202
- J. Zhu H. Bienayme) Wiley-VCH Verlag GmbH & Co. KGaA, Weinheim, Germany, Ed.
- Multicomponent reactions, (ed.:, J. Zhu, H. Bienayme,) Wiley-VCH Verlag GmbH & Co. KGaA, Weinheim, Germany. 2005, 468 pp
- (2005) Multicomponent Reactions

13
- 4243241249
- E. D. Cox J. M. Cook Chem. Rev. 1995 95 1797 1842
- (1995) Chem. Rev. , vol.95 , pp. 1797-1842
- Cox, E.D.¹ Cook, J.M.²

14
- 79953190018
- E. J. Glamkowski J. M. Fortunato J. Heterocycl. Chem. 1979 16 865 869
- (1979) J. Heterocycl. Chem. , vol.16 , pp. 865-869
- Glamkowski, E.J.¹ Fortunato, J.M.²

15
- 17844386805
- J. Yang X. Che Q. Dang Z. Wei S. Gao X. Bai Org. Lett. 2005 7 1541 1543
- (2005) Org. Lett. , vol.7 , pp. 1541-1543
- Yang, J.¹ Che, X.² Dang, Q.³ Wei, Z.⁴ Gao, S.⁵ Bai, X.⁶

16
- 20344383734
- B. Kundu D. Sawant P. Partani A. P. Kesarwani J. Org. Chem. 2005 70 4889 4892
- (2005) J. Org. Chem. , vol.70 , pp. 4889-4892
- Kundu, B.¹ Sawant, D.² Partani, P.³ Kesarwani, A.P.⁴

17
- 27744581943
- M. A. J. Duncton L. M. Smith II S. Burdzovic-Wizeman A. Burns H. Liu Y. Mao W. C. Wong A. S. Kiselyov J. Org. Chem. 2005 70 9629 9631
- (2005) J. Org. Chem. , vol.70 , pp. 9629-9631
- Duncton, M.A.J.¹ Smith, I.I.L.M.² Burdzovic-Wizeman, S.³ Burns, A.⁴ Liu, H.⁵ Mao, Y.⁶ Wong, W.C.⁷ Kiselyov, A.S.⁸

18
- 58649119073
- P. K. Agarwal D. Sawant S. Sharma B. Kundu Eur. J. Org. Chem. 2009 292 303
- (2009) Eur. J. Org. Chem. , pp. 292-303
- Agarwal, P.K.¹ Sawant, D.² Sharma, S.³ Kundu, B.⁴

19
- 70350686744
- B. Maiti, K. Chanda C. M. Sun Org. Lett. 2009 11 4826 4829
- (2009) Org. Lett. , vol.11 , pp. 4826-4829
- Maiti, B.¹ Chanda, K.² Sun, C.M.³

20
- 77956522594
- Y. S. Hsiao G. S. Yellol L. H Chen C. M. Sun J. Comb. Chem. 2010 12 723 732
- (2010) J. Comb. Chem. , vol.12 , pp. 723-732
- Hsiao, Y.S.¹ Yellol, G.S.² Chen, L.H.³ Sun, C.M.⁴

21
- 77952350796
- J. J. Lai D. B. Salunke C. M. Sun. Org. Lett. 2010 12 2174 2177
- (2010) Org. Lett. , vol.12 , pp. 2174-2177
- Lai, J.J.¹ Salunke, D.B.² Sun, C.M.³

22
- 78649676888
- G. S. Yellol T. W. Chung C. M. Sun Chem. Commun. 2010 46 9170 9172
- (2010) Chem. Commun. , vol.46 , pp. 9170-9172
- Yellol, G.S.¹ Chung, T.W.² Sun, C.M.³

23
- 43549104075
- K. M. Brummond D. Chen Org. Lett. 2008 10 705 708
- (2008) Org. Lett. , vol.10 , pp. 705-708
- Brummond, K.M.¹ Chen, D.²

24
- 66149162966
- A. R. Kelly J. Wei S. Kesavan J. C. Marie N. Windmon D. W. Young L. A. Marcaurelle Org. Lett. 2009 11 2257 2260
- (2009) Org. Lett. , vol.11 , pp. 2257-2260
- Kelly, A.R.¹ Wei, J.² Kesavan, S.³ Marie, J.C.⁴ Windmon, N.⁵ Young, D.W.⁶ Marcaurelle, L.A.⁷

25
- 0036355865
- C. M. Sun Methods Mol. Biol. 2002 201 141 166
- (2002) Methods Mol. Biol. , vol.201 , pp. 141-166
- Sun, C.M.¹

26
- 11144325118
- C. O. Kappe Angew. Chem., Int. Ed. 2004 43 6250 6284
- (2004) Angew. Chem., Int. Ed. , vol.43 , pp. 6250-6284
- Kappe, C.O.¹

27
- 70349972692
- K. Fuchibe T. Kaneko K. Mori T. Akiyama Angew. Chem., Int. Ed. 2009 48 8070 8073
- (2009) Angew. Chem., Int. Ed. , vol.48 , pp. 8070-8073
- Fuchibe, K.¹ Kaneko, T.² Mori, K.³ Akiyama, T.⁴

28
- 71049154982
- S. Laliberte P. K. Dornan A. Chen Tetrahedron Lett. 2010 51 363 366
- (2010) Tetrahedron Lett. , vol.51 , pp. 363-366
- Laliberte, S.¹ Dornan, P.K.² Chen, A.³

29
- 0023269042
- R. H. Dodd C. Ouannes M. C. Potier L. P. de Carvalho J. Rossier P. Potier J. Med. Chem. 1987 30 1248 1254
- (1987) J. Med. Chem. , vol.30 , pp. 1248-1254
- Dodd, R.H.¹ Ouannes, C.² Potier, M.C.³ De Carvalho, L.P.⁴ Rossier, J.⁵ Potier, P.⁶

30
- 0021339847
- E. J. Glamkowski J. M. Fortunato H. H. Ong R. C. Allen J. C. Wilker H. M. Geyer III J. Med. Chem. 1984 27 81 83
- (1984) J. Med. Chem. , vol.27 , pp. 81-83
- Glamkowski, E.J.¹ Fortunato, J.M.² Ong, H.H.³ Allen, R.C.⁴ Wilker, J.C.⁵ Geyer Iii, H.M.⁶

31
- 71049126548
- F Lovering J. Bikker C. Humblet J. Med. Chem. 2009 52 6752 6756
- (2009) J. Med. Chem. , vol.52 , pp. 6752-6756
- Lovering, F.¹ Bikker, J.² Humblet, C.³

32
- 84862512896
- S. Itsuno) Wiley-Blackwell: USA, All the microwave-assisted polymer-supported reactions were performed in CEM Discover Microwave in closed vessel system
- D. B. Salunke, C. M. Sun, Chiral Synthesis on Polymer Support: A Combinatorial Approach. In Polymeric Chiral Catalyst Design and Chiral Polymer Synthesis, (Ed.:, S. Itsuno,) Wiley-Blackwell: USA, 2010, Chapter 6
- (2010) Chiral Synthesis on Polymer Support: A Combinatorial Approach. in Polymeric Chiral Catalyst Design and Chiral Polymer Synthesis
- Salunke, D.B.¹ Sun, C.M.²

33
- 0028886751
- L. H. Zhang W. Meier E. Wats T. D. Costello P. Ma C. L. Ensinger J. M. Rodgers I. C. Jacobson P. Rajagopalan Tetrahedron Lett. 1995 36 8387 8390
- (1995) Tetrahedron Lett. , vol.36 , pp. 8387-8390
- Zhang, L.H.¹ Meier, W.² Wats, E.³ Costello, T.D.⁴ Ma, P.⁵ Ensinger, C.L.⁶ Rodgers, J.M.⁷ Jacobson, I.C.⁸ Rajagopalan, P.⁹

34
- 84980231074
- S. Raines S. Y. Chai F. P. Palopoli J. Heterocycl. Chem. 1976 13 711 716
- (1976) J. Heterocycl. Chem. , vol.13 , pp. 711-716
- Raines, S.¹ Chai, S.Y.² Palopoli, F.P.³

35
- 0041846797
- 2 using SHELXTL software package (Sheldrick, G. M. Acta Crystallogr.2008, A64, 112-122). Hydrogen atoms were included in the refinement as per the riding model. Crystallographic data for the structural analysis of 2a and 4k have been deposited with the Cambridge Crystallographic Data Centre, CCDC No.
- T. Hara K. Mori T. Mizugaki K. Ebitani K. Kaneda Tetrahedron Lett. 2003 44 6207 6210
- (2003) Tetrahedron Lett. , vol.44 , pp. 6207-6210
- Hara, T.¹ Mori, K.² Mizugaki, T.³ Ebitani, K.⁴ Kaneda, K.⁵

36
- 0003653449
- Oak Ridge National Laboratory, TN, USA
- M. N. Burnett, C. K. Johnson, ORTEP III, report ORNL-6895, Oak Ridge National Laboratory, TN, USA, 1996
- (1996) ORTEP III, Report ORNL-6895
- Burnett, M.N.¹ Johnson, C.K.²

37
- 36649014266
- C. Che J. Xiang G. X. Wang R. Fathi J. M. Quan Z. Yang J. Comb. Chem. 2007 9 982 989
- (2007) J. Comb. Chem. , vol.9 , pp. 982-989
- Che, C.¹ Xiang, J.² Wang, G.X.³ Fathi, R.⁴ Quan, J.M.⁵ Yang, Z.⁶

38
- 77956159549
- T. Yu J. R. Tagat A. D. Kerekes R. J. Doll Y. Zhang Y. Xiao S. Esposite D. B. Belanger P. J. Curran A. K. Mandal M. A. Siddiqui N. Y. Shih A. D. Basso M. Liu K. Gray S. Tevar J. Jones S. Lee L. Liang S. Ponery E. B. Smith A. Hruza J. Voigt L. Ramanathan W. Prosise M. Hu ACS Med. Chem. Lett. 2010 1 214 218
- (2010) ACS Med. Chem. Lett. , vol.1 , pp. 214-218
- Yu, T.¹ Tagat, J.R.² Kerekes, A.D.³ Doll, R.J.⁴ Zhang, Y.⁵ Xiao, Y.⁶ Esposite, S.⁷ Belanger, D.B.⁸ Curran, P.J.⁹ Mandal, A.K.¹⁰ Siddiqui, M.A.¹¹ Shih, N.Y.¹² Basso, A.D.¹³ Liu, M.¹⁴ Gray, K.¹⁵ Tevar, S.¹⁶ Jones, J.¹⁷ Lee, S.¹⁸ Liang, L.¹⁹ Ponery, S.²⁰ more..

39
- 41849136167
- V. Gracias Z. Ji I. Akritopoulou-Zanze C. Abad-Zapatero J. R. Huth D. Song P. J. Hajduk E. F. Johnson K. B. Glaser P. A. Marcotte L. Pease N. B. Soni K. D. Stewart S. K. Davidsen M. R. Michaelides S. W. Djuric Bioorg. Med. Chem. Lett. 2008 18 2691 2695
- (2008) Bioorg. Med. Chem. Lett. , vol.18 , pp. 2691-2695
- Gracias, V.¹ Ji, Z.² Akritopoulou-Zanze, I.³ Abad-Zapatero, C.⁴ Huth, J.R.⁵ Song, D.⁶ Hajduk, P.J.⁷ Johnson, E.F.⁸ Glaser, K.B.⁹ Marcotte, P.A.¹⁰ Pease, L.¹¹ Soni, N.B.¹² Stewart, K.D.¹³ Davidsen, S.K.¹⁴ Michaelides, M.R.¹⁵ Djuric, S.W.¹⁶

40
- 33746012247
- M. G. Achen S. A. Stacker Int. J. Cancer 2006 119 1755 1760
- (2006) Int. J. Cancer , vol.119 , pp. 1755-1760
- Achen, M.G.¹ Stacker, S.A.²

41
- 34047156551
- Y. Cao Q. Liu Adv. Cancer Res. 2007 97 203 224
- (2007) Adv. Cancer Res. , vol.97 , pp. 203-224
- Cao, Y.¹ Liu, Q.²

42
- 70549104050
- J. P. Sleeman W. Thiele Int. J. Cancer 2009 125 2747 2756
- (2009) Int. J. Cancer , vol.125 , pp. 2747-2756
- Sleeman, J.P.¹ Thiele, W.²

43
- 67649881870
- S. Hirakawa Cancer Sci. 2009 100 983 989
- (2009) Cancer Sci. , vol.100 , pp. 983-989
- Hirakawa, S.¹

44
- 33644822574
- J. L. Su P. C. Yang J. Y. Shih C. Y. Yang L. H. Wei C. Y. Hsieh C. H. Chou Y. M. Jeng M. Y. Wang K. J. Chang M. C. Hung M. L. Kuo Cancer Cell 2006 9 209 223
- (2006) Cancer Cell , vol.9 , pp. 209-223
- Su, J.L.¹ Yang, P.C.² Shih, J.Y.³ Yang, C.Y.⁴ Wei, L.H.⁵ Hsieh, C.Y.⁶ Chou, C.H.⁷ Jeng, Y.M.⁸ Wang, M.Y.⁹ Chang, K.J.¹⁰ Hung, M.C.¹¹ Kuo, M.L.¹²

45
- 35349001619
- S. Maekawa A. Iwasaki T. Shirakusa S. Enatsu T. Kawakami M. Kuroki M. Kuroki Anticancer Res. 2007 27 3735 3741
- (2007) Anticancer Res. , vol.27 , pp. 3735-3741
- Maekawa, S.¹ Iwasaki, A.² Shirakusa, T.³ Enatsu, S.⁴ Kawakami, T.⁵ Kuroki, M.⁶ Kuroki, M.⁷

46
- 11144241266
- F. Chen K. Takenaka E. Ogawa K. Yanagihara Y. Otake H. Wada F. Tanaka Clin. Cancer Res. 2004 10 8548 8553
- (2004) Clin. Cancer Res. , vol.10 , pp. 8548-8553
- Chen, F.¹ Takenaka, K.² Ogawa, E.³ Yanagihara, K.⁴ Otake, Y.⁵ Wada, H.⁶ Tanaka, F.⁷

47
- 1142299737
- X. E. Liu X. D. Sun J. M. Wu World J. Gastroenterol 2004 10 352 355
- (2004) World J. Gastroenterol , vol.10 , pp. 352-355
- Liu, X.E.¹ Sun, X.D.² Wu, J.M.³

48
- 28144454205
- X. M. Yu C. Y. Lo W. F. Chan K. Y. Lam P Leung J. M. Luk Clin. Cancer Res. 2005 11 8063 8069
- (2005) Clin. Cancer Res. , vol.11 , pp. 8063-8069
- Yu, X.M.¹ Lo, C.Y.² Chan, W.F.³ Lam, K.Y.⁴ Leung, P.⁵ Luk, J.M.⁶

49
- 57349130481
- V. Cohen-Kaplan I. Naroditsky A. Zetser N. Ilan I. Vlodavsky I. Doweck Int. J. Cancer 2008 123 2566 2573
- (2008) Int. J. Cancer , vol.123 , pp. 2566-2573
- Cohen-Kaplan, V.¹ Naroditsky, I.² Zetser, A.³ Ilan, N.⁴ Vlodavsky, I.⁵ Doweck, I.⁶

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