No association between TNFSF15 and IL23R with ulcerative colitis in Koreans

Journal of Human Genetics

Volumn 56, Issue 3, 2011, Pages 200-204

  Yang, Suk Kyun ^a   Jung, Yusun ^a   Hong, Myunghee ^a   Kim, Hyeri ^a   Ye, Byong Duk ^a   Lee, Inchul ^a   Song, Kyuyoung ^a  

^a University of Ulsan College of Medicine   (South Korea)

Author keywords

association; IL23R; Korean; TNFSF15; ulcerative colitis

Indexed keywords

INTERLEUKIN 23 RECEPTOR; VASCULAR ENDOTHELIAL GROWTH INHIBITOR;

ADULT; ALLELE; ARTICLE; CAUCASIAN; CHINESE; CONTROLLED STUDY; CROHN DISEASE; ETHNIC GROUP; FEMALE; GENETIC ASSOCIATION; GENETIC RISK; GENETIC SUSCEPTIBILITY; GENETIC VARIABILITY; GENOTYPE; HUMAN; KOREAN; MAJOR CLINICAL STUDY; MALE; SINGLE NUCLEOTIDE POLYMORPHISM; ULCERATIVE COLITIS;

ADULT; ALLELES; ASIAN CONTINENTAL ANCESTRY GROUP; COLITIS, ULCERATIVE; CROHN DISEASE; FEMALE; GENOTYPE; HUMANS; MALE; MIDDLE AGED; POLYMORPHISM, SINGLE NUCLEOTIDE; RECEPTORS, INTERLEUKIN; TUMOR NECROSIS FACTOR LIGAND SUPERFAMILY MEMBER 15; YOUNG ADULT;

EID: 79953206265     PISSN: 14345161     EISSN: None     Source Type: Journal    
DOI: 10.1038/jhg.2010.166     Document Type: Article

References (36)

1. Xavier, R. J. & Podolsky, D. K. Unravelling the pathogenesis of inflammatory bowel disease. Nature448, 427-434 (2007). (Pubitemid 47123518)
2. Tysk, C., Lindberg, E., Jarnerot, G. & Floderus-Myrhed, B. Ulcerativecolitis and Crohn's disease in an unselected population of monozygotic and dizygotic twins. A study of heritability and the influence of smoking. Gut 29, 990-996 (1988).
3. Orholm, M., Munkholm, P., Langholz, E., Nielsen, O. H., Sørensen, T. I. & Binder, V. Familial occurrence of inflammatory bowel disease. N. Engl. J. Med. 324, 84-88 (1991).
4. Loftus, E. V. Jr Clinical epidemiology of inflammatory bowel disease: incidence, prevalence, and environmental influences. Gastroenterology126, 1504-1517 (2004).
5. Thia, K. T., Loftus, E. V. Jr, Sandborn, W. J. & Yang, S.-K. An update on the epidemiology of inflammatory bowel disease in Asia. Am. J. Gastroenterol. 103, 3167-3182 (2008)
6. Yang, S.-K., Loftus, E. V. Jr & Sandborn, W. J. Epidemiology of inflammatory bowel disease in Asia. Inflamm. Bowel Dis. 7, 260-270 (2001). (Pubitemid 32776521)
7. Hampe, J., Cuthbert, A., Croucher, P. J., Mirza, M. M., Mascheretti, S., Fisher, S. et al. Association between insertion mutation in NOD2 gene and Crohn's disease in German and British populations. Lancet. 357, 1925-1928 (2001) (Pubitemid 32568333)
8. Hugot, J.-P., Chamaillard, M., Zouali, H., Lesage, S., Cézard, J. P., Belaiche, J. et al. Association of NOD2 leucine-rich repeatvariantswith susceptibility to Crohn's disease. Nature411, 599-603 (2001). (Pubitemid 32531408)
9. Ogura, Y., Bonen, D. K., Inohara, N., Nicolae, D. L., Chen, F. F., Ramos, R. et al. A frameshift mutation in NOD2 associated with susceptibility to Crohn's disease. Nature 411, 603-606 (2001). (Pubitemid 32531409)
10. Yamazaki, K., McGovern, D., Ragoussis, J., Paolucci, M., Butler, H., Jewell, D. et al. Single nucleotide polymorphisms in TNFSF15 confer susceptibility to Crohn's disease. Hum. Mol. Genet. 14, 3499-3506 (2005). (Pubitemid 41672132)
11. Duerr, R. H., Taylor, K. D., Brant, S. R., Rioux, J. D., Silverberg, M. S., Daly, M. J. et al. A genome-wide association study identifies IL23R as an inflammatory bowel disease gene. Science314, 1461-1463 (2006). (Pubitemid 44871953)
12. Rioux, J. D., Xavier, R. J., Taylor, K. D., Silverberg, M. S., Goyette, P., Huett, A. et al. Genome-wide association study identifies new susceptibility loci for Crohn's disease and implicates autophage in disease pathogenesis. Nat Genet. 39, 596-604 (2007). (Pubitemid 46676115)
13. Hampe, J., Franke, A., Rosenstiel, P., Till, A., Teuber, M., Huse, K. et al. Agenome-wide association scan of nonsynonymous SNPs identifies a susceptibility variant for Crohn's disease in ATG16L1. Nat Genet. 39, 207-211 (2007). (Pubitemid 46184351)
14. Libioulle, C., Louis, E., Hansoul, S., Sandor, C., Farnir, F., Franchimont, D. et al. Novel Crohn's disease locus identified by genome-wide association maps to a gene desert on 5p13.1 and modulates expression of PTGER4. PLoS Genet. 3, e58 (2007).
15. Franke, A., Hampe, J., Rosenstiel, P., Becker, C., Wagner, F., Häsler, R. et al. Systemic association mapping identifies NELL1 asa novel IBDdiseasegene. PLoSOne. 2, e691 (2007).
16. The Wellcome Trust Case Control Consortium. Genome-wide association study of 14 000 cases of seven common diseases and 3000 shared controls. Nature 447, 661-678 (2007).
17. Parkes, M., Barrett, J. C., Prescott, N. J., Tremelling, M., Anderson, C. A., Fisher, S. A. et al. Sequence variants in the autophage gene IRGM and multiple other replicating loci contribute to Crohn's disease susceptibility. Nat Genet. 39, 830-832 (2007). (Pubitemid 47014496)
18. Fisher, S. A., Tremelling, M., Anderson, C. A., Gwilliam, R., Bumpstead, S., Prescott, N. J. et al. Genetic determinants of ulcerative colitis include the ECM1 locus and five loci implicated in Crohn's disease. Nat Genet. 40, 710-712 (2008). (Pubitemid 351748865)
19. Franke, A., Balschun, T., Karlsen, T. H., Sventoraityte, J., Nikolaus, S., Mayr, G. et al. Sequence variants in IL10, ARPC2 and multiple other loci contribute to ulcerative colitis susceptibility. Nat Genet. 40, 1319-1323 (2008).
20. Asano, K., Matsushita, T., Umeno, J., Hosono, N., Takahashi, A., Kawaguchi, T. et al. A genome-wide association study identifies three new susceptibility loci for ulcerative colitis in the Japanese population. Nat Genet. 41, 1325-1329 (2009).
21. Silverberg, M. S., Cho, J. H., Rioux, J. D., McGovern, D. P., Wu, J., Annese, V. et al. Ulcerative colitis-risk loci on chromosomes 1p36 and 12q15 found by genome-wide association study. Nat Genet. 41, 216-220 (2009).
22. Barrett, J. C., Hansoul, S., Nicolae, D. L., Cho, J. H., Duerr, R. H., Rioux, J.D.et al. Genome-wide association defines morethan 30 distinct susceptibility loci for Crohn's disease. Nat Genet. 40, 955-962 (2008).
23. Anderson, C. A., Massey, D. C., Barrett, J. C., Prescott, N. J., Tremelling, M., Fisher, S. A. et al. Investigation of Crohn's disease risk loci in ulcerative colitis further defines their molecular relationship. Gastroenterology136, 523-529 (2009).
24. Franke, A., Balschun, T., Karlsen, T. H., Hedderich, J., May, S., Lu, T. et al. Replication of signals from recent studies of Crohn's disease identifies previously unknown disease loci for ulcerative colitis. Nat Genet. 40, 713-715 (2008). (Pubitemid 351748866)
25. Wang, K., Baldassano, R., Zhang, H., Qu, H. Q., Imielinski, M., Kugathasan, S. et al. Comparative genetic analysis of inflammatory bowel disease and type 1 diabetes implicates multiple loci with opposite effects. Hum. Mol. Genet. 19, 2059-2067 (2010).
26. Haritunians, T., Taylor, K., Targan, S. R., Dubinsky, M., Ippoliti, A., Kwon, S. et al. Genetic predictors of medically refractory ulcerative colitis. Inflamm. Bowel Dis. 16, 1830-1840 (2010).
27. Yang, S.-K., Lim, J., Chang, H. S., Lee, I., Li, Y., Liu, J. et al. Association of TNFSF15 with Crohn's disease in Koreans. Am. J. Gastroenterol. 103, 1437-1442 (2008). (Pubitemid 351813898)
28. Kakuta, Y., Kinouchi, Y., Negoro, K., Takahashi, S. & Shminosegawa, T. Association study of TNFSF15 polymorphisms in Japanese patients with inflammatory bowel disease. Gut55, 1527-1528 (2006). (Pubitemid 44476808)
29. Picornell, Y., Mei, L., Taylor, K., Yang, H., Targan, S. R. & Rotter, J. I. TNFSF15 is an ethnic-specific IBD gene. Inflamm. Bowel Dis. 13, 1333-1338 (2007). (Pubitemid 350206842)
30. Cho, J. H. & Weaver, C. T. The genetics of inflammatory bowel disease. Gastroenterology 133, 1327-1339 (2007) (Pubitemid 47494470)
31. Yang, S.-K., Park, M., Lim, J., Park, S. H., Ye, B. D., Lee, I. et al. Contributionof IL23R but not ATG16L1 to Crohn's disease susceptibility in Koreans. Inflamm. Bowel Dis. 15, 1385-1390 (2009).
32. Lennard-Jones, J. E. Classification of inflammatory bowel disease. Scand. J. Gastro-enterol. Suppl. 170, 2-6 (1989). (Pubitemid 20015811)
33. Park, S. H., Kim, Y. M., Yang, S.-K., Kim, S. H., Byeon, J. S., Myung, S. J. et al. Clinical features and natural history of ulcerative colitis in Korea. Inflamm. Bowel Dis. 13, 278-283 (2007). (Pubitemid 46465908)
34. Silverberg, M. S., Satsangi, J., Ahmad, T., Arnott, I. D., Bernstein, C. N., Brant, S. R. et al. Toward an integrated clinical, molecular and serological classification of inflammatory bowel disease: Report of a Working Party of the 2005 Montreal World Congress of Gastroenterology. Can. J. Gastroenterol. 19(Suppl A), 5-36 (2005).
35. Purcell, S., Neale, B., Todd-Brown, K., Thomas, L., Ferreira, M. A., Bender, D. et al. PLINK: atool setforwhole-genomeassociation and population-based linkageanalyses. Am. J. Hum. Genet. 81, 559-575 (2007).
36. Nakagome, S., Takeyama, Y., Mano, S., Sakisaka, S., Matsui, T., Kawamura, S. et al. Population-specific susceptibility to Crohn's disease and ulcerative colitis; dominant and recessive relative risks in the Japanese population. Ann. Hum. Genet. 74, 126-136 (2010).