Interfering with the inhibitory mechanism of serpins: Crystal structure of a complex formed between cleaved plasminogen activator inhibitor type 1 and a reactive-centre loop peptide

Structure

Volumn 6, Issue 5, 1998, Pages 627-636

  Xue, Yafeng ^a,b   Björquist, Petter ^b   Inghardt, Tord ^b   Linschoten, Marcel ^b   Musil, Djordje ^b   Sjölin, Lennart ^a   Deinum, Johanna ^b  

^a UNIVERSITY OF GOTHENBURG   (Sweden)

^b ASTRAZENECA R AND D   (Sweden)

Author keywords

Complex; Crystal structure; Peptide; Plasminogen activator inhibitor type 1; Serpin

Indexed keywords

BINDING KINETICS; CONFORMATIONAL TRANSITION; CRYSTAL STRUCTURE; ENZYME BINDING; ENZYME INACTIVATION; ENZYME INHIBITOR; ENZYME SUBSTRATE; GLYCOSYLATION; IMMOBILIZED ENZYME; MOLECULAR WEIGHT; PLASMINOGEN; SERINE PROTEINASE; SERINE PROTEINASE INHIBITOR; SURFACE PLASMON RESONANCE TECHNIQUE;

STAPHYLOCOCCUS PHAGE 3A;

EID: 0032524769     PISSN: 09692126     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0969-2126(98)00064-1     Document Type: Article

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