Hypoxia-induced cleavage of caspase-3 and DFF45/ICAD in human failed cardiomyocytes

American Journal of Physiology - Heart and Circulatory Physiology

Volumn 283, Issue 3 52-3, 2002, Pages

  Todor, Anastassia ^a   Sharov, Victor G ^a   Tanhehco, Elaine J ^a   Silverman, Norman ^a   Bernabei, Alvise ^a   Sabbah, Hani N ^a,b  

^a HENRY FORD HEART AND VASCULAR INSTITUTE   (United States)

^b HENRY FORD HOSPITAL   (United States)

Author keywords

Apoptosis; Heart failure

Indexed keywords

CASPASE 3; CASPASE 3 INHIBITOR; DNA FRAGMENT;

ADULT; APOPTOSIS; ARTICLE; CLINICAL ARTICLE; CONTROLLED STUDY; FEMALE; HEART DILATATION; HEART FAILURE; HEART MUSCLE CELL; HEART TRANSPLANTATION; HEMODYNAMICS; HUMAN; HUMAN CELL; HYPOXIA; ISCHEMIC HEART DISEASE; MALE; PRIORITY JOURNAL; PROTEIN EXPRESSION; STRESS; WESTERN BLOTTING;

EID: 0036352616     PISSN: 03636135     EISSN: None     Source Type: Journal    
DOI: 10.1152/ajpheart.01003.2001     Document Type: Article

References (40)

1. Preservation of mitochondrial structure and function after Bid- or Bax-mediated cytochrome c release
2. Mitochondrial transmembrane ion distribution during anoxia
3. Protein and nucleic-acid blotting and immunobiochemical detection
4. Mitochondrial control of apoptosis: The role of cytochrome c
5. Cardiomyocyte remodeling during myocardial hibernation and atrial fibrillation: Prelude to apoptosis
6. A caspase-activated DNase that degrades DNA during apoptosis, and its inhibitor ICAD
7. Apoptosis, Bcl-2 and proliferation cell nuclear antigen in the failing human heart: Observations made after implantation of left ventricular assist device
8. Effects of ECE inhibition on cardiomyocyte apoptosis in dogs with heart failure
9. Role of inositol 1,4,5-triphosphate receptors in regulating apoptotic signaling and heart failure
10. Caspase-3 is required for DNA fragmentation and morphological changes associated with apoptosis
11. Cleavage of Bid caspase 8 mediates the mitochondrial damage in the Fas pathway of apoptosis
12. max and the transient outward current
13. Bid, a Bcl-2 interacting protein, mediates cytochrome c release from mitochondria in response to activation of cell surface death receptors
14. Caspase activation and mitochondrial cytochrome c release during hypoxia-mediated apoptosis of adult ventricular myocytes
15. Apoptosis in myocytes in end-stage heart failure
16. Apoptosis in the failing human heart
17. Myocyte loss in chronic heart failure
18. Is apoptosis a mechanism of cell death of cardiomyocytes in chronic chagasic myocarditis?
19. Remodeling of the cardiac interstitium in the progression of heart failure
20. Mitochondrial abnormalities in myocardium of dogs with chronic heart failure
21. Inhibition of apoptosis-associated DNA fragmentation activity in nonapoptotic cells: The role of DNA fragmentation factor-45 (DFF45/ICAD)
22. Cleavage of CAD inhibitor in CAD activation and DNA degradation during apoptosis
23. Cardiomyocyte apoptosis and progression of heart failure to transplantation
24. Apoptosis in human acute myocardial infarction
25. The role of apoptosis in dilated cardiomyopathy
26. Hypoxia and hypoxia/reoxygenation activate p65PAK, p38 mitogen-activated protein kinase (MAPK), and stress-activated protein kinase (SAPK) in cultured rat cardiac myocytes
27. Evidence of cardiocyte apoptosis in myocardium of dogs with chronic heart failure
28. Myocyte adaptation to chronic hypoxia and development of tolerance to subsequent acute severe hypoxia
29. Oncoprotein-mediated signaling cascade stimulates c-Jun activity by phosphorylation of serines 63 and 73
30. Increased p53 protein expression in human failing myocardium
31. Mitochondria as regulators of apoptosis: Doubt no more
32. Electrophoretic transfer of proteins from two dimensional gel to sheets and their detection. Two dimensional gel electrophoresis of proteins
33. Immunoautoradiographic detection of proteins after electrophoretic transfer from gels to diazo-paper: Analysis of adenovirus encoded proteins
34. Hypoxia induces apoptosis with enhanced expression of Fas antigen messenger RNA in cultured neonatal rat cardiomyocytes
35. Discordant regulation of apoptosis associated proteins in cardiomyocytes isolated from patients with ischemic versus idiopathic dilated cardiomyopathy
36. Early apoptosis in human myocardial infarcts
37. Ca-induced apoptosis through calcineurin dephosphorylation of Bad
38. Cardiac muscle cell hypertrophy and apoptosis induced by distinct members of the p38 mitogen-activated protein kinase family
39. Hypoxia-activated apoptosis of cardiac myocytes requires reoxygenation or a pH shift and is independent of p53
40. Essential contribution of caspase 3/CPP32 to apoptosis and its associated nuclear changes