Monoacylated cellular prion protein modifies cell membranes, inhibits cell signaling, and reduces prion formation

Journal of Biological Chemistry

Volumn 286, Issue 11, 2011, Pages 8752-8758

  Bate, Clive ^a   Williams, Alun ^a,b  

^a ROYAL VETERINARY COLLEGE   (United Kingdom)

^b UNIVERSITY OF CAMBRIDGE   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

ACYL CHAIN; CELL LINES; CELL SIGNALING; CELLULAR PRION PROTEINS; CHEMICAL COMPOSITIONS; CHOLESTEROL CONTENT; CONTROL-CELL; DETERGENT-RESISTANT MEMBRANES; GLYCOSYLPHOSPHATIDYLINOSITOL ANCHORS; ISOFORMS; LIPID RAFT; MICROENVIRONMENTS; NEURONAL CELL; PAINTING TECHNIQUES; PHOSPHOLIPASE A; PRION DISEASE;

CELL CULTURE; CELL MEMBRANES; CHOLESTEROL; MEMBRANES; NEURODEGENERATIVE DISEASES; SIGNALING;

SCANDIUM;

CHOLESTEROL; CYTOSOLIC PHOSPHOLIPASE A2; GLYCOSYLPHOSPHATIDYLINOSITOL; PHOSPHATIDYLINOSITOL DIACYLGLYCEROL LYASE; PRION PROTEIN;

ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; BRAIN NERVE CELL; CELL LINE; CELL MEMBRANE; CELL STRAIN SCGT1; CELL STRAIN SCN2A; CELL STRAIN SMB; CONTROLLED STUDY; LIPID RAFT; MOUSE; NONHUMAN; PRION DISEASE; PRIORITY JOURNAL; PROTEIN FUNCTION; PROTEIN ISOLATION; PROTEIN MODIFICATION; SIGNAL TRANSDUCTION;

ACETYLATION; ANIMALS; CELL LINE; CELL MEMBRANE; CHOLESTEROL; GPI-LINKED PROTEINS; MICE; PHOSPHOLIPASES A2, CYTOSOLIC; PRION DISEASES; PRPC PROTEINS; PRPSC PROTEINS; SIGNAL TRANSDUCTION;

MUS;

EID: 79953164948     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M110.186833     Document Type: Article

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