Synthesis and biological activity of novel retinamide and retinoate derivatives

Chemical and Pharmaceutical Bulletin

Volumn 52, Issue 5, 2004, Pages 501-506

  Um, Soo Jong ^a   Kwon, Youn Ja ^a   Han, Hye Sook ^a   Park, Si Ho ^a   Park, Myoung Soon ^a   Rho, Young Soy ^b   Sin, Hong Sig ^a  

^a Sejong University   (South Korea)

^b Chonbuk National University   (South Korea)

Author keywords

Cytotoxicity; Derivative; Retinamide; Retinoate; Retinoic acid receptor (RAR)

Indexed keywords

2 [3,7 DIMETHYL 9 (2,6,6 TRIMETHYL 1 CYCLOHEXENYL)NONA 2,4,6,8 TETRAENOYLAMINO] 5 HYDROXYPHENYLBUTANOATE; 4 (BUTYRYLAMINO)PHENYL 3,7 DIMETHYL 9 (2,6,6 TRIMETHYL 1 CYCLOHEXENYL) 2,4,6,8 NONATETRAENOATE; 4 [3,7 DIMETHYL 9 (2,6,6 TRIMETHYL 1 CYCLOHEXENYL)NONA 2,4,6,8 TETRAENOYLAMINO]PHENYLBUTANOATE; 4 AMINO 2 (BUTYRYLAMINO)PHENYL 3,7 DIMETHYL 9 (2,6,6 TRIMETHYL 1 CYCLOHEXENYL) 2,4,6,8 NONATETRAENOATE; 4 AMINO 2 (BUTYRYLOXY)PHENYL 3,7 DIMETHYL 9 (2,6,6 TRIMETHYL 1 CYCLOHEXENYL) 2,4,6,8 NONATETRAENOATE; 4 AMINO 3 (BUTYRYLOXY)PHENYL 3,7 DIMETHYL 9 (2,6,6 TRIMETHYL 1 CYCLOHEXENYL) 2,4,6,8 NONATETRAENOATE; 4 AMINOPHENYL 3,7 DIMETHYL 9 (2,6,6 TRIMETHYL 1 CYCLOHEXENYL) 2,4,6,8 NONATETRAENOATE; 5 [3,7 DIMETHYL 9 (2,6,6 TRIMETHYL 1 CYCLOHEXENYL)NONA 2,4,6,8 TETRAENOYLAMINO] 2 HYDROXYPHENYLBUTANOATE; [3,7 DIMETHYL 9 (2,6,6 TRIMETHYL 1 CYCLOHEXENYL)NONA 2,4,6,8 TETRAENOYLAMINO](3 BUTYLAMINO 4 HYDROXY)PHENYLAMIDE; [3,7 DIMETHYL 9 (2,6,6 TRIMETHYL 1 CYCLOHEXENYL)NONA 2,4,6,8 TETRAENOYLAMINO](4 HYDROXY)PHENYLAMIDE; AMIDE; AMINOPHENOL DERIVATIVE; ANTINEOPLASTIC AGENT; CARBOXYLIC ACID DERIVATIVE; LIGAND; RETINOIC ACID DERIVATIVE; RETINOIC ACID RECEPTOR; RETINOIC ACID RECEPTOR BETA; RETINOIC ACID RECEPTOR GAMMA; RETINOID DERIVATIVE; UNCLASSIFIED DRUG; DRUG DERIVATIVE; FENRETINIDE; RETINAMIDE; RETINOIC ACID;

ACYLATION; ANIMAL CELL; ARTICLE; CANCER CELL; CELL STRAIN COS1; CELL STRAIN HCT116; CONTROLLED STUDY; CYTOTOXICITY; DOSE RESPONSE; DRUG ACTIVITY; DRUG STRUCTURE; DRUG SYNTHESIS; HUMAN; HUMAN CELL; IC 50; NONHUMAN; STEREOCHEMISTRY; ANIMAL; CERCOPITHECUS; METABOLISM; SYNTHESIS;

ANIMALS; CERCOPITHECUS AETHIOPS; COS CELLS; FENRETINIDE; HCT116 CELLS; HUMANS; RECEPTORS, RETINOIC ACID; TRETINOIN;

EID: 7944234835     PISSN: 00092363     EISSN: 13475223     Source Type: Journal    
DOI: 10.1248/cpb.52.501     Document Type: Article

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