Development of PLZF-expressing innate T cells

Current Opinion in Immunology

Volumn 23, Issue 2, 2011, Pages 220-227

  Alonzo, Eric S ^a   Sant'Angelo, Derek B ^a,b  

^a MEMORIAL SLOAN KETTERING CANCER CENTER   (United States)

^b Weill Cornell Graduate School of Biomedical Sciences   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

PROMYELOCYTIC LEUKEMIA ZINC FINGER; T LYMPHOCYTE RECEPTOR; TRANSCRIPTION FACTOR; UNCLASSIFIED DRUG;

B LYMPHOCYTE; CD4+ T LYMPHOCYTE; CD8+ T LYMPHOCYTE; CELL INTERACTION; CELL LINEAGE; CELL MATURATION; LYMPHOCYTE DIFFERENTIATION; LYMPHOCYTE FUNCTION; NATURAL KILLER T CELL; NONHUMAN; PHENOTYPE; PROTEIN DOMAIN; PROTEIN EXPRESSION; REVIEW; SIGNAL TRANSDUCTION; T LYMPHOCYTE; T LYMPHOCYTE ACTIVATION; THYMOCYTE; THYMUS; TRANSCRIPTION REGULATION; TRANSGENE;

ANIMALS; CELL DIFFERENTIATION; HUMANS; IMMUNITY, INNATE; KRUPPEL-LIKE TRANSCRIPTION FACTORS; RECEPTORS, ANTIGEN, T-CELL; SIGNAL TRANSDUCTION; T-LYMPHOCYTES;

EID: 79953076755     PISSN: 09527915     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.coi.2010.12.016     Document Type: Review

References (49)

1. Bhandoola A., von Boehmer H., Petrie H.T., Zuniga-Pflucker J.C. Commitment and developmental potential of extrathymic and intrathymic T cell precursors: plenty to choose from. Immunity 2007, 26:678-689.
2. Das R., Sant'Angelo D.B., Nichols K.E. Transcriptional control of invariant NKT cell development. Immunol Rev 2010, 238:195-215.
3. Kelly K.F., Daniel J.M. POZ for effect-POZ-ZF transcription factors in cancer and development. Trends Cell Biol 2006, 16:578-587.
4. Maeda T., Merghoub T., Hobbs R.M., Dong L., Maeda M., Zakrzewski J., van den Brink M.R., Zelent A., Shigematsu H., Akashi K., et al. Regulation of B versus T lymphoid lineage fate decision by the proto-oncogene LRF. Science 2007, 316:860-866.
5. He X., Dave V.P., Zhang Y., Hua X., Nicolas E., Xu W., Roe B.A., Kappes D.J. The zinc finger transcription factor Th-POK regulates CD4 versus CD8 T-cell lineage commitment. Nature 2005, 433:826-833.
6. Duy C., Yu J.J., Nahar R., Swaminathan S., Kweon S.M., Polo J.M., Valls E., Klemm L., Shojaee S., Cerchietti L., et al. BCL6 is critical for the development of a diverse primary B cell repertoire. J Exp Med 2010, 207:1209-1221.
7. Nurieva R.I., Chung Y., Martinez G.J., Yang X.O., Tanaka S., Matskevitch T.D., Wang Y.H., Dong C. Bcl6 mediates the development of T follicular helper cells. Science 2009, 325:1001-1005.
8. Sakaguchi S., Hombauer M., Bilic I., Naoe Y., Schebesta A., Taniuchi I., Ellmeier W. The zinc-finger protein MAZR is part of the transcription factor network that controls the CD4 versus CD8 lineage fate of double-positive thymocytes. Nat Immunol 2010, 11:442-448.
9. Dent A.L., Shaffer A.L., Yu X., Allman D., Staudt L.M. Control of inflammation, cytokine expression, and germinal center formation by BCL-6. Science 1997, 276:589-592.
10. Fukuda T., Yoshida T., Okada S., Hatano M., Miki T., Ishibashi K., Okabe S., Koseki H., Hirosawa S., Taniguchi M., et al. Disruption of the Bcl6 gene results in an impaired germinal center formation. J Exp Med 1997, 186:439-448.
11. Kovalovsky D., Uche O.U., Eladad S., Hobbs R.M., Yi W., Alonzo E., Chua K., Eidson M., Kim H.J., Im J.S., et al. The BTB-zinc finger transcriptional regulator PLZF controls the development of invariant natural killer T cell effector functions. Nat Immunol 2008, 9:1055-1064.
12. Savage A.K., Constantinides M.G., Han J., Picard D., Martin E., Li B., Lantz O., Bendelac A. The transcription factor PLZF directs the effector program of the NKT cell lineage. Immunity 2008, 29:391-403.
13. Bendelac A., Savage P.B., Teyton L. The biology of NKT cells. Annu Rev Immunol 2007, 25:297-336.
14. Raberger J., Schebesta A., Sakaguchi S., Boucheron N., Blomberg K.E., Berglof A., Kolbe T., Smith C.I., Rulicke T., Ellmeier W. The transcriptional regulator PLZF induces the development of CD44 high memory phenotype T cells. Proc Natl Acad Sci U S A 2008, 105:17919-17924.
15. Kovalovsky D., Alonzo E.S., Uche O.U., Eidson M., Nichols K.E., Sant'Angelo D.B. PLZF induces the spontaneous acquisition of memory/effector functions in T cells independently of NKT cell-related signals. J Immunol 2010, 184:6746-6755.
16. Kreslavsky T., Savage A.K., Hobbs R., Gounari F., Bronson R., Pereira P., Pandolfi P.P., Bendelac A., von Boehmer H. TCR-inducible PLZF transcription factor required for innate phenotype of a subset of gammadelta T cells with restricted TCR diversity. Proc Natl Acad Sci U S A 2009, 106:12453-12458.
17. Felices M., Yin C.C., Kosaka Y., Kang J., Berg L.J. Tec kinase Itk in gammadeltaT cells is pivotal for controlling IgE production in vivo. Proc Natl Acad Sci U S A 2009, 106:8308-8313.
18. Alonzo E.S., Gottschalk R.A., Das J., Egawa T., Hobbs R.M., Pandolfi P.P., Pereira P., Nichols K.E., Koretzky G.A., Jordan M.S., et al. Development of promyelocytic zinc finger and ThPOK-expressing innate gamma delta T cells is controlled by strength of TCR signaling and Id3. J Immunol 2010, 184:1268-1279.
19. Verykokakis M., Boos M.D., Bendelac A., Adams E.J., Pereira P., Kee B.L. Inhibitor of DNA binding 3 limits development of murine slam-associated adaptor protein-dependent 'innate' gammadelta T cells. PLoS One 2010, 5:e9303.
20. Broussard C., Fleischacker C., Horai R., Chetana M., Venegas A.M., Sharp L.L., Hedrick S.M., Fowlkes B.J., Schwartzberg P.L. Altered development of CD8+ T cell lineages in mice deficient for the Tec kinases Itk and Rlk. Immunity 2006, 25:93-104.
21. Weinreich M.A., Odumade O.A., Jameson S.C., Hogquist K.A. T cells expressing the transcription factor PLZF regulate the development of memory-like CD8+ T cells. Nat Immunol 2010, 11:709-716.
22. Verykokakis M., Boos M.D., Bendelac A., Kee B.L. SAP protein-dependent natural killer T-like cells regulate the development of CD8(+) T cells with innate lymphocyte characteristics. Immunity 2010, 33:203-215.
23. Weinreich M.A., Takada K., Skon C., Reiner S.L., Jameson S.C., Hogquist K.A. KLF2 transcription-factor deficiency in T cells results in unrestrained cytokine production and upregulation of bystander chemokine receptors. Immunity 2009, 31:122-130.
24. Qi Q., Xia M., Hu J., Hicks E., Iyer A., Xiong N., August A. Enhanced development of CD4+ gammadelta T cells in the absence of Itk results in elevated IgE production. Blood 2009, 114:564-571.
25. Xu D., Holko M., Sadler A.J., Scott B., Higashiyama S., Berkofsky-Fessler W., McConnell M.J., Pandolfi P.P., Licht J.D., Williams B.R. Promyelocytic leukemia zinc finger protein regulates interferon-mediated innate immunity. Immunity 2009, 30:802-816.
26. Li H., Dai M., Zhuang Y: A T cell intrinsic role of Id3 in a mouse model for primary Sjogren's syndrome. Immunity 2004, 21:551-560.
27. Hayes S.M., Li L., Love P.E. TCR signal strength influences alphabeta/gammadelta lineage fate. Immunity 2005, 22:583-593.
28. Haks M.C., Lefebvre J.M., Lauritsen J.P., Carleton M., Rhodes M., Miyazaki T., Kappes D.J., Wiest D.L. Attenuation of gammadeltaTCR signaling efficiently diverts thymocytes to the alphabeta lineage. Immunity 2005, 22:595-606.
29. Ueda-Hayakawa I., Mahlios J., Zhuang Y. Id3 restricts the developmental potential of gamma delta lineage during thymopoiesis. J Immunol 2009, 182:5306-5316.
30. Lauritsen J.P., Wong G.W., Lee S.Y., Lefebvre J.M., Ciofani M., Rhodes M., Kappes D.J., Zuniga-Pflucker J.C., Wiest D.L. Marked induction of the helix-loop-helix protein Id3 promotes the gammadelta T cell fate and renders their functional maturation Notch independent. Immunity 2009, 31:565-575.
31. Jordan M.S., Smith J.E., Burns J.C., Austin J.E., Nichols K.E., Aschenbrenner A.C., Koretzky G.A. Complementation in trans of altered thymocyte development in mice expressing mutant forms of the adaptor molecule SLP76. Immunity 2008, 28:359-369.
32. Bendelac A. Positive selection of mouse NK1+ T cells by CD1-expressing cortical thymocytes. J Exp Med 1995, 182:2091-2096.
33. Jordan M.A., Fletcher J.M., Pellicci D., Baxter A.G. Slamf1, the NKT cell control gene Nkt1. J Immunol 2007, 178:1618-1627.
34. Griewank K., Borowski C., Rietdijk S., Wang N., Julien A., Wei D.G., Mamchak A.A., Terhorst C., Bendelac A. Homotypic interactions mediated by Slamf1 and Slamf6 receptors control NKT cell lineage development. Immunity 2007, 27:751-762.
35. Nichols K.E., Hom J., Gong S.Y., Ganguly A., Ma C.S., Cannons J.L., Tangye S.G., Schwartzberg P.L., Koretzky G.A., Stein P.L. Regulation of NKT cell development by SAP, the protein defective in XLP. Nat Med 2005, 11:340-345.
36. Chung B., Aoukaty A., Dutz J., Terhorst C., Tan R. Signaling lymphocytic activation molecule-associated protein controls NKT cell functions. J Immunol 2005, 174:3153-3157.
37. Gadue P., Morton N., Stein P.L. The Src family tyrosine kinase Fyn regulates natural killer T cell development. J Exp Med 1999, 190:1189-1196.
38. Chan B., Lanyi A., Song H.K., Griesbach J., Simarro-Grande M., Poy F., Howie D., Sumegi J., Terhorst C., Eck M.J. SAP couples Fyn to SLAM immune receptors. Nat Cell Biol 2003, 5:155-160.
39. Latour S., Roncagalli R., Chen R., Bakinowski M., Shi X., Schwartzberg P.L., Davidson D., Veillette A. Binding of SAP SH2 domain to FynT SH3 domain reveals a novel mechanism of receptor signalling in immune regulation. Nat Cell Biol 2003, 5:149-154.
40. Engel I., Hammond K., Sullivan B.A., He X., Taniuchi I., Kappes D., Kronenberg M. Co-receptor choice by V alpha14i NKT cells is driven by Th-POK expression rather than avoidance of CD8-mediated negative selection. J Exp Med 2010, 207:1015-1029.
41. Park K., He X., Lee H.O., Hua X., Li Y., Wiest D., Kappes D.J. TCR-mediated ThPOK induction promotes development of mature (CD24-) gammadelta thymocytes. EMBO J 2010, 29:2329-2341.
42. Wang L., Carr T., Xiong Y., Wildt K.F., Zhu J., Feigenbaum L., Bendelac A., Bosselut R. The sequential activity of Gata3 and Thpok is required for the differentiation of CD1d-restricted CD4+ NKT cells. Eur J Immunol 2010, 40:2385-2390.
43. Wei D.G., Lee H., Park S.H., Beaudoin L., Teyton L., Lehuen A., Bendelac A. Expansion and long-range differentiation of the NKT cell lineage in mice expressing CD1d exclusively on cortical thymocytes. J Exp Med 2005, 202:239-248.
44. Schumann J., Pittoni P., Tonti E., Macdonald H.R., Dellabona P., Casorati G. Targeted expression of human CD1d in transgenic mice reveals independent roles for thymocytes and thymic APCs in positive and negative selection of Valpha14i NKT cells. J Immunol 2005, 175:7303-7310.
45. Anderson G., Partington K.M., Jenkinson E.J. Differential effects of peptide diversity and stromal cell type in positive and negative selection in the thymus. J Immunol 1998, 161:6599-6603.
46. Li W., Kim M.G., Gourley T.S., McCarthy B.P., Sant'Angelo D.B., Chang C.H. An alternate pathway for CD4 T cell development: thymocyte-expressed MHC class II selects a distinct T cell population. Immunity 2005, 23:375-386.
47. Choi E.Y., Jung K.C., Park H.J., Chung D.H., Song J.S., Yang S.D., Simpson E., Park S.H. Thymocyte-thymocyte interaction for efficient positive selection and maturation of CD4 T cells. Immunity 2005, 23:387-396.
48. Lee Y.J., Jeon Y.K., Kang B.H., Chung D.H., Park C.G., Shin H.Y., Jung K.C., Park S.H. Generation of PLZF+ CD4+ T cells via MHC class II-dependent thymocyte-thymocyte interaction is a physiological process in humans. J Exp Med 2010, 207:237-246.
49. Li L., Leid M., Rothenberg E.V. An early T cell lineage commitment checkpoint dependent on the transcription factor Bcl11b. Science 2010, 329:89-93.