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Volumn 29, Issue 14, 2010, Pages 2329-2341

TCR-mediated ThPOK induction promotes development of mature (CD24-) γ δ thymocytes

Author keywords

T lymphocyte; T lymphocyte development; ThPOK transcription factor

Indexed keywords

ANTIBODY; CD24 ANTIGEN; CIS ACTING ELEMENT; LIGAND; T LYMPHOCYTE RECEPTOR; THPOK TRANSCRIPTION FACTOR; UNCLASSIFIED DRUG; ZINC FINGER PROTEIN;

EID: 77954886412     PISSN: 02614189     EISSN: 14602075     Source Type: Journal    
DOI: 10.1038/emboj.2010.113     Document Type: Article
Times cited : (42)

References (43)
  • 1
    • 45549106387 scopus 로고    scopus 로고
    • An autonomous CDR3delta is sufficient for recognition of the non-classical MHC class i molecules T10 and T22 by gammadelta T cells
    • Adams EJ, Strop P, Shin S, Chien YH, Garcia KC (2008) An autonomous CDR3delta is sufficient for recognition of the non-classical MHC class I molecules T10 and T22 by gammadelta T cells. Nat Immunol 9: 777-784
    • (2008) Nat Immunol , vol.9 , pp. 777-784
    • Adams, E.J.1    Strop, P.2    Shin, S.3    Chien, Y.H.4    Garcia, K.C.5
  • 3
    • 0031597422 scopus 로고    scopus 로고
    • The homogeneity of the TCRdelta repertoire expressed by the Thy-1dull gamma-delta Tcell population is due to cellular selection
    • Azuara V, Lembezat MP, Pereira P (1998) The homogeneity of the TCRdelta repertoire expressed by the Thy-1dull gamma-delta Tcell population is due to cellular selection. Eur J Immunol 28: 3456-3467
    • (1998) Eur J Immunol , vol.28 , pp. 3456-3467
    • Azuara, V.1    Lembezat, M.P.2    Pereira, P.3
  • 4
    • 0031052817 scopus 로고    scopus 로고
    • A novel subset of adult gamma delta thymocytes that secretes a distinct pattern of cytokines and expresses a very restricted Tcell receptor repertoire
    • Azuara V, Levraud JP, Lembezat MP, Pereira P (1997) A novel subset of adult gamma delta thymocytes that secretes a distinct pattern of cytokines and expresses a very restricted Tcell receptor repertoire. Eur J Immunol 27: 544-553
    • (1997) Eur J Immunol , vol.27 , pp. 544-553
    • Azuara, V.1    Levraud, J.P.2    Lembezat, M.P.3    Pereira, P.4
  • 6
    • 43549105168 scopus 로고    scopus 로고
    • The stream of precursors that colonizes the thymus proceeds selectively through the early T lineage precursor stage of Tcell development
    • Benz C, Martins VC, Radtke F, Bleul CC (2008) The stream of precursors that colonizes the thymus proceeds selectively through the early T lineage precursor stage of Tcell development. J Exp Med 205: 1187-1199
    • (2008) J Exp Med , vol.205 , pp. 1187-1199
    • Benz, C.1    Martins, V.C.2    Radtke, F.3    Bleul, C.C.4
  • 8
    • 0033181325 scopus 로고    scopus 로고
    • Signals transduced by CD3epsilon, but not by surface pre-TCR complexes, are able to induce maturation of an early thymic lymphoma in vitro
    • Carleton M, Ruetsch NR, Berger MA, Rhodes M, Kaptik S, Wiest DL (1999) Signals transduced by CD3epsilon, but not by surface pre-TCR complexes, are able to induce maturation of an early thymic lymphoma in vitro. J Immunol 163: 2576-2585
    • (1999) J Immunol , vol.163 , pp. 2576-2585
    • Carleton, M.1    Ruetsch, N.R.2    Berger, M.A.3    Rhodes, M.4    Kaptik, S.5    Wiest, D.L.6
  • 9
    • 0032493380 scopus 로고    scopus 로고
    • HD mice: A novel mouse mutant with a specific defect in the generation of CD4(+) Tcells
    • Davé VP, Allman D, Keefe R, Hardy RR, Kappes DJ (1998) HD mice: a novel mouse mutant with a specific defect in the generation of CD4(+) Tcells. Proc Natl Acad Sci USA 95: 8187-8192
    • (1998) Proc Natl Acad Sci USA , vol.95 , pp. 8187-8192
    • Davé, V.P.1    Allman, D.2    Keefe, R.3    Hardy, R.R.4    Kappes, D.J.5
  • 10
    • 77949879961 scopus 로고    scopus 로고
    • Spontaneous development of IL-17-producing gd T cells in the thymus occurs via a TGF-b1-dependent mechanism
    • Do J-S, Fink PJ, Li L, Spllski R, Robinson J, Leonard WL, Letterio JL, Min B (2010) Spontaneous development of IL-17-producing gd T cells in the thymus occurs via a TGF-b1-dependent mechanism. J Immunol 184: 1675-1679
    • (2010) J Immunol , vol.184 , pp. 1675-1679
    • Do, J.-S.1    Fink, P.J.2    Li, L.3    Spllski, R.4    Robinson, J.5    Leonard, W.L.6    Letterio, J.L.7    Min, B.8
  • 11
    • 0033006012 scopus 로고    scopus 로고
    • The regulation of CD4 and CD8 coreceptor gene expression during T cell development
    • Ellmeier W, Sawada M, Littman DR (1999) The regulation of CD4 and CD8 coreceptor gene expression during T cell development. Ann Rev Immunol 17: 523-554
    • (1999) Ann Rev Immunol , vol.17 , pp. 523-554
    • Ellmeier, W.1    Sawada, M.2    Littman, D.R.3
  • 12
    • 77952304517 scopus 로고    scopus 로고
    • Co-receptor choice by Va14i NKT cells is driven by Th-POK expression rather than avoidance of CD8-mediated negative selection
    • Engel I, Hammond K, Sullivan BA, He X, Taniuchi I, Kappes D, Kronenberg M (2010) Co-receptor choice by Va14i NKT cells is driven by Th-POK expression rather than avoidance of CD8-mediated negative selection. J Exp Med 207: 1015-1029
    • (2010) J Exp Med , vol.207 , pp. 1015-1029
    • Engel, I.1    Hammond, K.2    Sullivan, B.A.3    He, X.4    Taniuchi, I.5    Kappes, D.6    Kronenberg, M.7
  • 15
    • 19344369077 scopus 로고    scopus 로고
    • TCR signal strength influences alphabeta/gammadelta lineage fate
    • Hayes SM, Li L, Love PE (2005) TCR signal strength influences alphabeta/gammadelta lineage fate. Immunity 22: 583-593
    • (2005) Immunity , vol.22 , pp. 583-593
    • Hayes, S.M.1    Li, L.2    Love, P.E.3
  • 16
    • 0037306064 scopus 로고    scopus 로고
    • An architectural perspective on signaling by the pre-, alphabeta and gammadelta T cell receptors
    • Hayes SM, Shores EW, Love PE (2003) An architectural perspective on signaling by the pre-, alphabeta and gammadelta T cell receptors. Immunol Rev 191: 28-37
    • (2003) Immunol Rev , vol.191 , pp. 28-37
    • Hayes, S.M.1    Shores, E.W.2    Love, P.E.3
  • 17
    • 14544288635 scopus 로고    scopus 로고
    • The zinc finger transcription factor Th-POK regulates CD4 versus CD8 T-cell lineage commitment
    • He X, Dave VP, Zhang Y, Hua X, Nicolas E, Xu W, Roe BA, Kappes DJ (2005) The zinc finger transcription factor Th-POK regulates CD4 versus CD8 T-cell lineage commitment. Nature 433: 826-833
    • (2005) Nature , vol.433 , pp. 826-833
    • He, X.1    Dave, V.P.2    Zhang, Y.3    Hua, X.4    Nicolas, E.5    Xu, W.6    Roe, B.A.7    Kappes, D.J.8
  • 18
    • 33644640619 scopus 로고    scopus 로고
    • CD4/CD8 lineage commitment: Light at the end of the tunnel?
    • He X, Kappes DJ (2006) CD4/CD8 lineage commitment: light at the end of the tunnel? Curr Opin Immunol 18: 135-142
    • (2006) Curr Opin Immunol , vol.18 , pp. 135-142
    • He, X.1    Kappes, D.J.2
  • 19
    • 40249095991 scopus 로고    scopus 로고
    • CD4-CD8 lineage commitment is regulated by a silencer element at the ThPOK transcription-factor locus
    • He X, Park K, Wang H, Zhang Y, Hua X, Li Y, Kappes DJ (2008) CD4-CD8 lineage commitment is regulated by a silencer element at the ThPOK transcription-factor locus. Immunity 28: 346-358
    • (2008) Immunity , vol.28 , pp. 346-358
    • He, X.1    Park, K.2    Wang, H.3    Zhang, Y.4    Hua, X.5    Li, Y.6    Kappes, D.J.7
  • 20
    • 0025212263 scopus 로고
    • T-cell receptor gamma delta and gamma transgenic mice suggest a role of a gamma gene silencer in the generation of alpha beta T cells
    • Ishida I, Verbeek S, Bonneville M, Itohara S, Berns A, Tonegawa S (1990) T-cell receptor gamma delta and gamma transgenic mice suggest a role of a gamma gene silencer in the generation of alpha beta T cells. Proc Natl Acad Sci USA 87: 3067-3071
    • (1990) Proc Natl Acad Sci USA , vol.87 , pp. 3067-3071
    • Ishida, I.1    Verbeek, S.2    Bonneville, M.3    Itohara, S.4    Berns, A.5    Tonegawa, S.6
  • 22
    • 0033527615 scopus 로고    scopus 로고
    • Regulation of lineage commitment distinct from positive selection
    • Keefe R, Dave V, Allman D, Wiest D, Kappes DJ (1999) Regulation of lineage commitment distinct from positive selection. Science 286: 1149-1153
    • (1999) Science , vol.286 , pp. 1149-1153
    • Keefe, R.1    Dave, V.2    Allman, D.3    Wiest, D.4    Kappes, D.J.5
  • 23
    • 0027266856 scopus 로고
    • Emigration of selected subsets of gd+ Tcells from the adult murine thymus
    • Kelly KA, Pearse M, Lefrancois L, Scollay R (1993) Emigration of selected subsets of gd+ Tcells from the adult murine thymus. Int Immunol 5: 331-335
    • (1993) Int Immunol , vol.5 , pp. 331-335
    • Kelly, K.A.1    Pearse, M.2    Lefrancois, L.3    Scollay, R.4
  • 24
    • 0025331311 scopus 로고
    • Analysis of recent thymic emigrants with subset-and maturity-related markers
    • Kelly KA, Scollay R (1990) Analysis of recent thymic emigrants with subset-and maturity-related markers. Int Immunol 2: 419-425
    • (1990) Int Immunol , vol.2 , pp. 419-425
    • Kelly, K.A.1    Scollay, R.2
  • 25
    • 43549085301 scopus 로고    scopus 로고
    • T cell receptor-instructed alphabeta versus gammadelta lineage commitment revealed by single-cell analysis
    • Kreslavsky T, Garbe AI, Krueger A, von Boehmer H (2008) T cell receptor-instructed alphabeta versus gammadelta lineage commitment revealed by single-cell analysis. J Exp Med 205: 1173-1186
    • (2008) J Exp Med , vol.205 , pp. 1173-1186
    • Kreslavsky, T.1    Garbe, A.I.2    Krueger, A.3    Von Boehmer, H.4
  • 27
    • 33847625852 scopus 로고    scopus 로고
    • On the road: Progress in finding the unique pathway of invariant NKT cell differentiation
    • Kronenberg M, Engel I (2007) On the road: progress in finding the unique pathway of invariant NKT cell differentiation. Curr Opin Immunol 19: 186-193
    • (2007) Curr Opin Immunol , vol.19 , pp. 186-193
    • Kronenberg, M.1    Engel, I.2
  • 28
    • 33645088926 scopus 로고    scopus 로고
    • Recent insights into the signals that control alphabeta/gamma-delta- lineage fate
    • Lauritsen JP, Haks MC, Lefebvre JM, Kappes DJ, Wiest DL (2006) Recent insights into the signals that control alphabeta/gamma-delta-lineage fate. Immunol Rev 209: 176-190
    • (2006) Immunol Rev , vol.209 , pp. 176-190
    • Lauritsen, J.P.1    Haks, M.C.2    Lefebvre, J.M.3    Kappes, D.J.4    Wiest, D.L.5
  • 29
  • 30
    • 0034771897 scopus 로고    scopus 로고
    • Tissue-specific segregation of TCRgamma delta+ NKTcells according to phenotype TCR repertoire and activation status: Parallels with TCR alphabeta+NKT cells
    • Lees RK, Ferrero I, MacDonald HR (2001) Tissue-specific segregation of TCRgamma delta+ NKTcells according to phenotype TCR repertoire and activation status: parallels with TCR alphabeta+NKT cells. Eur J Immunol 31: 2901-2909
    • (2001) Eur J Immunol , vol.31 , pp. 2901-2909
    • Lees, R.K.1    Ferrero, I.2    MacDonald, H.R.3
  • 31
    • 68649126866 scopus 로고    scopus 로고
    • Interleukin-17-producing gammadelta T cells selectively expand in response to pathogen products and environmental signals
    • Martin B, Hirota K, Cua DJ, Stockinger B, Veldhoen M (2009) Interleukin-17-producing gammadelta T cells selectively expand in response to pathogen products and environmental signals. Immunity 31: 321-330
    • (2009) Immunity , vol.31 , pp. 321-330
    • Martin, B.1    Hirota, K.2    Cua, D.J.3    Stockinger, B.4    Veldhoen, M.5
  • 32
    • 0029988961 scopus 로고    scopus 로고
    • MHC class II-specific T cells can develop in the CD8 lineage when CD4 is absent
    • Matechak EO, Killeen N, Hedrick SM, Fowlkes BJ (1996) MHC class II-specific T cells can develop in the CD8 lineage when CD4 is absent. Immunity 4: 337-347
    • (1996) Immunity , vol.4 , pp. 337-347
    • Matechak, E.O.1    Killeen, N.2    Hedrick, S.M.3    Fowlkes, B.J.4
  • 33
    • 0032766646 scopus 로고    scopus 로고
    • Impaired immune responses and B-cell proliferation in mice lacking the Id3 gene
    • Pan L, Sato S, Frederick JP, Sun XH, Zhuang Y (1999) Impaired immune responses and B-cell proliferation in mice lacking the Id3 gene. Mol Cell Biol 19: 5969-5980
    • (1999) Mol Cell Biol , vol.19 , pp. 5969-5980
    • Pan, L.1    Sato, S.2    Frederick, J.P.3    Sun, X.H.4    Zhuang, Y.5
  • 34
    • 0026507498 scopus 로고
    • Blockade of transgenic gamma delta T cell development in beta 2-microglobulin deficient mice
    • Pereira P, Zijlstra M, McMaster J, Loring JM, Jaenisch R, Tonegawa S (1992) Blockade of transgenic gamma delta T cell development in beta 2-microglobulin deficient mice. EMBO J 11: 25-31
    • (1992) EMBO J , vol.11 , pp. 25-31
    • Pereira, P.1    Zijlstra, M.2    McMaster, J.3    Loring, J.M.4    Jaenisch, R.5    Tonegawa, S.6
  • 35
    • 2942516896 scopus 로고    scopus 로고
    • Heterogeneity among DN1 prothymocytes reveals multiple progenitors with different capacities to generate T cell and non-T cell lineages
    • Porritt HE, Rumfelt LL, Tabrizifard S, Schmitt TM, Zúñiga- Pflücker JC, Petrie HT (2004) Heterogeneity among DN1 prothymocytes reveals multiple progenitors with different capacities to generate T cell and non-T cell lineages. Immunity 20: 735-745
    • (2004) Immunity , vol.20 , pp. 735-745
    • Porritt, H.E.1    Rumfelt, L.L.2    Tabrizifard, S.3    Schmitt, T.M.4    Zúñiga-Pflücker, J.C.5    Petrie, H.T.6
  • 37
    • 70449730937 scopus 로고    scopus 로고
    • ThPOK derepression is required for robust CD8 T cell responses to viral infection
    • Setoguchi R, Taniuchi I, Bevan MJ (2009) ThPOK derepression is required for robust CD8 T cell responses to viral infection. J Immunol 183: 4467-4474
    • (2009) J Immunol , vol.183 , pp. 4467-4474
    • Setoguchi, R.1    Taniuchi, I.2    Bevan, M.J.3
  • 38
    • 58749116295 scopus 로고    scopus 로고
    • Identification of CD25+ gamma delta T cells as fetal thymus-derived naturally occurring IL-17 producers
    • Shibata K, Yamada H, Nakamura R, Sun X, Itsumi M, Yoshikai Y (2008) Identification of CD25+ gamma delta T cells as fetal thymus-derived naturally occurring IL-17 producers. J Immunol 181: 5940-5947
    • (2008) J Immunol , vol.181 , pp. 5940-5947
    • Shibata, K.1    Yamada, H.2    Nakamura, R.3    Sun, X.4    Itsumi, M.5    Yoshikai, Y.6
  • 40
    • 0032472869 scopus 로고    scopus 로고
    • Lifespan of g/d T cells
    • Tough DF, Sprent J (1998) Lifespan of g/d T cells. J Exp Med 187: 357-365
    • (1998) J Exp Med , vol.187 , pp. 357-365
    • Tough, D.F.1    Sprent, J.2
  • 41
    • 66949160434 scopus 로고    scopus 로고
    • Id3 restricts the developmental potential of gamma delta lineage during thymo-poiesis
    • Ueda-Hayakawa I, Mahlios J, Zhuang Y (2009) Id3 restricts the developmental potential of gamma delta lineage during thymo-poiesis. J Immunol 182: 5306-5316
    • (2009) J Immunol , vol.182 , pp. 5306-5316
    • Ueda-Hayakawa, I.1    Mahlios, J.2    Zhuang, Y.3
  • 42
    • 33744977004 scopus 로고    scopus 로고
    • Interplay between RORgt, Egr3, and e proteins controls proliferation in response to Pre-TCR signals
    • Xi H, Schwartz R, Engel I, Murre C, Kersh GJ (2006) Interplay between RORgt, Egr3, and E proteins controls proliferation in response to Pre-TCR signals. Immunity 24: 813-826
    • (2006) Immunity , vol.24 , pp. 813-826
    • Xi, H.1    Schwartz, R.2    Engel, I.3    Murre, C.4    Kersh, G.J.5
  • 43
    • 0027245020 scopus 로고
    • Development of gdT cells in the adult murine thymus
    • Zorbas M, Scollay R (1993) Development of gdT cells in the adult murine thymus. Eur J Immunol 23: 1655-1660
    • (1993) Eur J Immunol , vol.23 , pp. 1655-1660
    • Zorbas, M.1    Scollay, R.2


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