NKT cells: The culprits of sepsis?

Journal of Surgical Research

Volumn 167, Issue 1, 2011, Pages 87-95

  Leung, Briana ^a   Harris, Hobart W ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

apolipoprotein E; cecal ligation and puncture; lipopolysaccharide; natural killer T cells; sepsis

Indexed keywords

APOLIPOPROTEIN E; GAMMA INTERFERON; HIGH DENSITY LIPOPROTEIN; INTERLEUKIN 1; INTERLEUKIN 12; LIPOPOLYSACCHARIDE; LOW DENSITY LIPOPROTEIN RECEPTOR; TUMOR NECROSIS FACTOR; VERY LOW DENSITY LIPOPROTEIN;

CELL ACTIVATION; CELL LINEAGE; CELL SELECTION; CYTOKINE PRODUCTION; CYTOKINE RELEASE; HUMAN; HYPERLIPIDEMIA; IMMUNE RESPONSE; IMMUNOCOMPETENT CELL; IMMUNOREGULATION; INFLAMMATION; NATURAL KILLER CELL; NONHUMAN; PRIORITY JOURNAL; REVIEW; SEPTIC SHOCK; SPHINGOMONAS;

ADAPTIVE IMMUNITY; APOLIPOPROTEINS E; HUMANS; IMMUNITY, INNATE; NATURAL KILLER T-CELLS; SEPSIS; SHOCK, SEPTIC;

EID: 79953044423     PISSN: 00224804     EISSN: 10958673     Source Type: Journal    
DOI: 10.1016/j.jss.2010.09.038     Document Type: Review

References (88)

1. A. Balato, D. Unutmaz, and A.A. Gaspari Natural killer T cells: An unconventional T-cell subset with diverse effector and regulatory functions J Invest Dermatol 129 2009 1628
2. D.I. Godfrey, K.J. Hammond, and L.D. Poulton NKT cells: Facts, functions and fallacies Immunol Today 21 2000 573
3. D.I. Godfrey, H.R. MacDonald, and M. Kronenberg NKT cells: What's in a name? Nat Rev Immunol 4 2004 231
4. E.M. Beckman, S.A. Porcelli, and C.T. Morita Recognition of a lipid antigen by CD1-restricted α/β+ T cells Nature 372 1994 691
5. A.O. Speak, M. Salio, and D.C. Neville Implications for invariant natural killer T cell ligands due to the restricted presence of isoglobotrihexosylceramide in mammals Proc Natl Acad Sci USA 104 2007 5971
6. S. Porubsky, A.O. Speak, and B. Luckow Normal development and function of invariant natural killer T cells in mice with isoglobotrihexosylceramide (iGb3) deficiency Proc Natl Acad Sci USA 104 2007 5977
7. T. Natori, Y. Koezuka, and T. Higa Agelasphins, novel α-galactosylceramides from the marine sponge Agelas mauritianus Tetrahedron Lett 34 1993 5591
8. T. Natori, M. Morita, K. Akimoto, and Y. Koezuka Agelasphins, novel antitumor and immunostimulatory cerebrosides from the marine sponge Agelas mauritianus Tetrahedron 50 1994 2771
9. A. Jahng, I. Maricic, and C. Aguilera Prevention of autoimmunity by targeting a distinct, noninvariant CD1d-reactive T cell population reactive to sulfatide J Exp Med 199 2004 947
10. D.M. Zajonc, I. Maricic, and D. Wu Structural basis for CD1d presentation of a sulfatide derived from myelin and its implications for autoimmunity J Exp Med 202 2005 1517
11. R.C. Halder, C. Aguilera, and I. Maricic Type II NKT cell-mediated anergy induction in type I NKT cells prevents inflammatory liver disease J Clin Invest 117 2007 2302
12. A. Bendelac, P.B. Savage, and L. Teyton The biology of NKT cells Annu Rev Immunol 25 2007 297
13. T. Yoshimoto, and W.E. Paul CD4pos, NK1.1pos T cells promptly produce interleukin 4 in response to in vivo challenge with anti-CD3 J Exp Med 179 1994 1285
14. H. Arase, N. Arase, and Y. Kobayashi Cytotoxicity of fresh NK1.1+ T cell receptor α/β+ thymocytes against a CD4+8+ thymocyte population associated with intact Fas antigen expression on the target J Exp Med 180 1994 423
15. M.J. Smyth, K.Y. Thia, and S.E. Street Differential tumor surveillance by natural killer (NK) and NKT cells J Exp Med 191 2000 661
16. M. Skold, and S.M. Behar Role of CD1d-restricted NKT cells in microbial immunity Infect Immun 71 2003 5447
17. D.C. Angus, W.T. Linde-Zwirble, and J. Lidicker Epidemiology of severe sepsis in the United States: Analysis of incidence, outcome, and associated costs of care Crit Care Med 29 2001 1303
18. N.C. Riedemann, R.F. Guo, and P.A. Ward Novel strategies for the treatment of sepsis Nat Med 9 2003 517
19. M.J. Sweet, and D.A. Hume Endotoxin signal transduction in macrophages J Leukoc Biol 60 1996 8
20. J.C. Chow, D.W. Young, and D.T. Golenbock Toll-like receptor-4 mediates lipopolysaccharide-induced signal transduction J Biol Chem 274 1999 10689
21. S.M. Opal, P.J. Scannon, and J.L. Vincent Relationship between plasma levels of lipopolysaccharide (LPS) and LPS-binding protein in patients with severe sepsis and septic shock J Infect Dis 180 1999 1584
22. S.T. Qureshi, L. Lariviere, and G. Leveque Endotoxin-tolerant mice have mutations in Toll-like receptor 4 (Tlr4) J Exp Med 189 1999 615
23. R.B. Yang, M.R. Mark, and A. Gray Toll-like receptor-2 mediates lipopolysaccharide-induced cellular signaling Nature 395 1998 284
24. A.F. Suffredini, R.E. Fromm, and M.M. Parker The cardiovascular response of normal humans to the administration of endotoxin N Engl J Med 321 1989 280
25. A.M. Taveira da Silva, H.C. Kaulbach, and F.S. Chuidian Brief report: Shock and multiple-organ dysfunction after self-administration of Salmonella endotoxin N Engl J Med 328 1993 1457
26. A. Billiau γ-Interferon: The match that lights the fire? Immunol Today 9 1988 37
27. L. Ozmen, M. Pericin, and J. Hakimi Interleukin 12, interferon- γ, and tumor necrosis factor α are the key cytokines of the generalized Shwartzman reaction J Exp Med 180 1994 907
28. M. Wysocka, M. Kubin, and L.Q. Vieira Interleukin-12 is required for interferon- γ production and lethality in lipopolysaccharide-induced shock in mice Eur J Immunol 25 1995 672
29. T. Kawamura, K. Takeda, and S.K. Mendiratta Critical role of NK1+ T cells in IL-12-induced immune responses in vivo J Immunol 160 1998 16
30. M. Takahashi, K. Ogasawara, and K. Takeda LPS induces NK1.1+ α/β T cells with potent cytotoxicity in the liver of mice via production of IL-12 from Kupffer cells J Immunol 156 1996 2436
31. K. Ogasawara, K. Takeda, and W. Hashimoto Involvement of NK1+ T cells and their IFN- γ production in the generalized Shwartzman reaction J Immunol 160 1998 3522
32. F. Dieli, G. Sireci, and D. Russo Resistance of natural killer T cell-deficient mice to systemic Shwartzman reaction J Exp Med 192 2000 1645
33. H. Ito, N. Koide, and F. Hassan Lethal endotoxic shock using α-galactosylceramide sensitization as a new experimental model of septic shock Lab Invest 86 2006 254
34. N. Singh, S. Hong, and D.C. Scherer Cutting edge: Activation of NK T cells by CD1d and α-galactosylceramide directs conventional T cells to the acquisition of a Th2 phenotype J Immunol 163 1999 2373
35. G. Sireci, M.P. La Manna, and D. Di Liberto Prophylaxis of lipopolysaccharide-induced shock by α-galactosylceramide J Leukoc Biol 84 2008 550
36. G. Sireci, M.P. La Manna, and C. Di Sano Pivotal advance: α-Galactosylceramide induces protection against lipopolysaccharide-induced shock J Leukoc Biol 81 2007 607
37. K.O. Yu, and S.A. Porcelli The diverse functions of CD1d-restricted NKT cells and their potential for immunotherapy Immunol Lett 100 2005 42
38. N.A. Nagarajan, and M. Kronenberg Invariant NKT cells amplify the innate immune response to lipopolysaccharide J Immunol 178 2007 2706
39. K.A. Wichterman, A.E. Baue, and I.H. Chaudry Sepsis and septic shock-A review of laboratory models and a proposal J Surg Res 29 1980 189
40. W.J. Hubbard, M. Choudhry, and M.G. Schwacha Cecal ligation and puncture Shock 24 Suppl 1 2005 52
41. M. Lisbonne, S. Diem, and A. de Castro Keller Cutting edge: Invariant V α 14 NKT cells are required for allergen-induced airway inflammation and hyper-reactivity in an experimental asthma model J Immunol 171 2003 1637
42. M.W. Teng, S. Yue, and J. Sharkey CD1d activation and blockade: A new antitumor strategy J Immunol 182 2009 3366
43. D. Zeng, Y. Liu, and S. Sidobre Activation of natural killer T cells in NZB/W mice induces Th1-type immune responses exacerbating lupus J Clin Invest 112 2003 1211
44. R.J. Rhee, S. Carlton, and J.L. Lomas Inhibition of CD1d activation suppresses septic mortality: A role for NK-T cells in septic immune dysfunction J Surg Res 115 2003 74
45. E.R. Sherwood, C.Y. Lin, and W. Tao β2 Microglobulin knockout mice are resistant to lethal intra-abdominal sepsis Am J Respir Crit Care Med 167 2003 1641
46. C.K. Hu, F. Venet, and D.S. Heffernan The role of hepatic invariant NKT cells in systemic/local inflammation and mortality during polymicrobial septic shock J Immunol 182 2009 2467
47. J. Mattner, K.L. Debord, and N. Ismail Exogenous and endogenous glycolipid antigens activate NKT cells during microbial infections Nature 434 2005 525
48. M. Brigl, L. Bry, and S.C. Kent Mechanism of CD1d-restricted natural killer T cell activation during microbial infection Nat Immunol 4 2003 1230
49. M. Taniguchi, K. Seino, and T. Nakayama The NKT cell system: Bridging innate and acquired immunity Nat Immunol 4 2003 1164
50. A.O. Etogo, J. Nunez, and C.Y. Lin NK but not CD1-restricted NKT cells facilitate systemic inflammation during polymicrobial intra-abdominal sepsis J Immunol 180 2008 6334
51. C. Carnaud, D. Lee, and O. Donnars Cutting edge: Cross-talk between cells of the innate immune system: NKT cells rapidly activate NK cells J Immunol 163 1999 4647
52. S. Banerjee, and J.N. Bhaduri Serum protein-bound carbohydrates and lipids in cholera Proc Soc Exp Biol Med 101 1959 340
53. J.I. Gallin, D. Kaye, and W.M. O'Leary Serum lipids in infection N Engl J Med 281 1969 1081
54. J.S. Samra, L.K. Summers, and K.N. Frayn Sepsis and fat metabolism Br J Surg 83 1996 1186
55. R.J. Ulevitch, and A.R. Johnston The modification of biophysical and endotoxic properties of bacterial lipopolysaccharides by serum J Clin Invest 62 1978 1313
56. R.J. Ulevitch, A.R. Johnston, and D.B. Weinstein New function for high density lipoproteins. Their participation in intravascular reactions of bacterial lipopolysaccharides J Clin Invest 64 1979 1516
57. R.J. Ulevitch, A.R. Johnston, and D.B. Weinstein New function for high density lipoproteins. Isolation and characterization of a bacterial lipopolysaccharide-high density lipoprotein complex formed in rabbit plasma J Clin Invest 67 1981 827
58. E.B. Eichbaum, H.W. Harris, and J.P. Kane Chylomicrons can inhibit endotoxin activity in vitro J Surg Res 51 1991 413
59. H.W. Harris, E.B. Eichbaum, and J.P. Kane Detection of endotoxin in triglyceride-rich lipoproteins in vitro J Lab Clin Med 118 1991 186
60. H.W. Harris, C. Grunfeld, and K.R. Feingold Human very low density lipoproteins and chylomicrons can protect against endotoxin-induced death in mice J Clin Invest 86 1990 696
61. K.R. Feingold, J.L. Funk, and A.H. Moser Role for circulating lipoproteins in protection from endotoxin toxicity Infect Immun 63 1995 2041
62. T.E. Read, C. Grunfeld, and Z. Kumwenda Triglyceride-rich lipoproteins improve survival when given after endotoxin in rats Surgery 117 1995 62
63. T.E. Read, C. Grunfeld, and Z.L. Kumwenda Triglyceride-rich lipoproteins prevent septic death in rats J Exp Med 182 1995 267
64. A.T. Casas, A.P. Hubsch, and J.E. Doran Effects of reconstituted high-density lipoprotein in persistent gram-negative bacteremia Am Surg 62 1996 350
65. J.I. Cue, J.T. DiPiro, and L.J. Brunner Reconstituted high density lipoprotein inhibits physiologic and tumor necrosis factor α responses to lipopolysaccharide in rabbits Arch Surg 129 1994 193
66. A.P. Hubsch, F.S. Powell, and P.G. Lerch A reconstituted, apolipoprotein A-I containing lipoprotein reduces tumor necrosis factor release and attenuates shock in endotoxemic rabbits Circ Shock 40 1993 14
67. D. Pajkrt, J.E. Doran, and F. Koster Anti-inflammatory effects of reconstituted high-density lipoprotein during human endotoxemia J Exp Med 184 1996 1601
68. T.S. Parker, D.M. Levine, and J.C. Chang Reconstituted high-density lipoprotein neutralizes gram-negative bacterial lipopolysaccharides in human whole blood Infect Immun 63 1995 253
69. P.C. Rensen, M. Oosten, and E. Bilt Human recombinant apolipoprotein E redirects lipopolysaccharide from Kupffer cells to liver parenchymal cells in rats In vivo J Clin Invest 99 1997 2438
70. D.M. Levine, T.S. Parker, and T.M. Donnelly In vivo protection against endotoxin by plasma high density lipoprotein Proc Natl Acad Sci USA 90 1993 12040
71. H.W. Harris, D.C. Rockey, and D.M. Young Diet-induced protection against lipopolysaccharide includes increased hepatic NO production J Surg Res 82 1999 339
72. E. Liberopoulos, K. Siamopoulos, and M. Elisaf Apolipoprotein E and renal disease Am J Kidney Dis 43 2004 223
73. R.W. Mahley, and S.C. Rall Jr. Apolipoprotein E: Far more than a lipid transport protein Annu Rev Genomics Hum Genet 1 2000 507
74. R.J. Moore, R.M. Chamberlain, and F.R. Khuri Apolipoprotein E and the risk of breast cancer in African-American and non-Hispanic White women. A review Oncology 66 2004 79
75. P. Rensen, M. Van Oosten, and E. Van Amersfoort Apolipoprotein E is increased by bacterial LPS in vivo and protects against LPS-induced lethality Circulation 98 Suppl. 1998 I-305
76. N. de Bont, M.G. Netea, and P.N. Demacker Apolipoprotein E knock-out mice are highly susceptible to endotoxemia and Klebsiella pneumoniae infection J Lipid Res 40 1999 680
77. M. Van Oosten, P.C. Rensen, and E.S. Van Amersfoort Apolipoprotein E protects against bacterial lipopolysaccharide-induced lethality. A new therapeutic approach to treat gram-negative sepsis J Biol Chem 276 2001 8820
78. O.M. Kattan, F.B. Kasravi, and E.L. Elford Apolipoprotein E-mediated immune regulation in sepsis J Immunol 181 2008 1399
79. P. van den Elzen, S. Garg, and L. Leon Apolipoprotein-mediated pathways of lipid antigen presentation Nature 437 2005 906
80. R.L. Raffai, and K.H. Weisgraber Hypomorphic apolipoprotein E mice: A new model of conditional gene repair to examine apolipoprotein E-mediated metabolism J Biol Chem 277 2002 11064
81. H.W. Harris Apolipoprotein E: From Alzheimer's to sepsis Crit Care Med 33 2005 2696
82. E.W. Moretti, R.W. Morris, and M. Podgoreanu APOE polymorphism is associated with risk of severe sepsis in surgical patients Crit Care Med 33 2005 2521
83. J.R. Lynch, W. Tang, and H. Wang APOE genotype and an ApoE-mimetic peptide modify the systemic and central nervous system inflammatory response J Biol Chem 278 2003 48529
84. H. Wang, D.J. Christensen, and M.P. Vitek APOE genotype affects outcome in a murine model of sepsis: Implications for a new treatment strategy Anaesth Intensive Care 37 2009 38
85. K. Chuang, E.L. Elford, and J. Tseng An expanding role for apolipoprotein E in sepsis and inflammation Am J Surg 2010 (in press)
86. S. Fujii Exploiting dendritic cells and natural killer T cells in immunotherapy against malignancies Trends Immunol 29 2008 242
87. J. Dong, C.A. Peters-Libeu, and K.H. Weisgraber Interaction of the N-terminal domain of apolipoprotein E4 with heparin Biochemistry 40 2001 2826
88. J.L. Vincent, Q. Sun, and M.J. Dubois Clinical trials of immunomodulatory therapies in severe sepsis and septic shock Clin Infect Dis 34 2002 1084