메뉴 건너뛰기




Volumn 46, Issue 4, 2011, Pages 710-719

Unique gene expression patterns indicate microglial contribution to neural stem cell recovery following irradiation

Author keywords

Fluorescence activated cell sorting; Growth factors; Hippocampus; Microglia; Radiation injury; Stem cells; Subventricular zone

Indexed keywords

GROWTH FACTOR;

EID: 79953030496     PISSN: 10447431     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.mcn.2011.02.001     Document Type: Article
Times cited : (20)

References (65)
  • 1
    • 10344263377 scopus 로고    scopus 로고
    • Pathogenesis of irradiation-induced cognitive dysfunction
    • Abayomi O.K. Pathogenesis of irradiation-induced cognitive dysfunction. Acta Oncol. 1996, 35:659-663.
    • (1996) Acta Oncol. , vol.35 , pp. 659-663
    • Abayomi, O.K.1
  • 3
    • 1542268981 scopus 로고    scopus 로고
    • For the long run: maintaining germinal niches in the adult brain
    • Alvarez-Buylla A., Lim D.A. For the long run: maintaining germinal niches in the adult brain. Neuron 2004, 41:683-686.
    • (2004) Neuron , vol.41 , pp. 683-686
    • Alvarez-Buylla, A.1    Lim, D.A.2
  • 4
    • 3442876969 scopus 로고    scopus 로고
    • Normalization of real-time quantitative reverse transcription-PCR data: a model-based variance estimation approach to identify genes suited for normalization, applied to bladder and colon cancer data sets
    • Andersen C.L., Jensen J.L., Orntoft T.F. Normalization of real-time quantitative reverse transcription-PCR data: a model-based variance estimation approach to identify genes suited for normalization, applied to bladder and colon cancer data sets. Cancer Res. 2004, 64:5245-5250.
    • (2004) Cancer Res. , vol.64 , pp. 5245-5250
    • Andersen, C.L.1    Jensen, J.L.2    Orntoft, T.F.3
  • 7
    • 0035004457 scopus 로고    scopus 로고
    • Postnatal steroids and neurodevelopmental outcomes: a problem in the making
    • Barrington K.J. Postnatal steroids and neurodevelopmental outcomes: a problem in the making. Pediatrics 2001, 107:1425-1426.
    • (2001) Pediatrics , vol.107 , pp. 1425-1426
    • Barrington, K.J.1
  • 8
    • 26944461658 scopus 로고    scopus 로고
    • Sox2 expression defines a heterogeneous population of neurosphere-forming cells in the adult murine brain
    • Brazel C.Y., Limke T.L., Osborne J.K., Miura T., Cai J., Pevny L., Rao M.S. Sox2 expression defines a heterogeneous population of neurosphere-forming cells in the adult murine brain. Aging Cell 2005, 4:197-207.
    • (2005) Aging Cell , vol.4 , pp. 197-207
    • Brazel, C.Y.1    Limke, T.L.2    Osborne, J.K.3    Miura, T.4    Cai, J.5    Pevny, L.6    Rao, M.S.7
  • 9
    • 30044434850 scopus 로고    scopus 로고
    • Microglia activated by IL-4 or IFN-gamma differentially induce neurogenesis and oligodendrogenesis from adult stem/progenitor cells
    • Butovsky O., Ziv Y., Schwartz A., Landa G., Talpalar A.E., Pluchino S., Martino G., Schwartz M. Microglia activated by IL-4 or IFN-gamma differentially induce neurogenesis and oligodendrogenesis from adult stem/progenitor cells. Mol. Cell. Neurosci. 2006, 31:149-160.
    • (2006) Mol. Cell. Neurosci. , vol.31 , pp. 149-160
    • Butovsky, O.1    Ziv, Y.2    Schwartz, A.3    Landa, G.4    Talpalar, A.E.5    Pluchino, S.6    Martino, G.7    Schwartz, M.8
  • 10
    • 0037194887 scopus 로고    scopus 로고
    • LeX/ssea-1 is expressed by adult mouse CNS stem cells, identifying them as nonependymal
    • Capela A., Temple S. LeX/ssea-1 is expressed by adult mouse CNS stem cells, identifying them as nonependymal. Neuron 2002, 35:865-875.
    • (2002) Neuron , vol.35 , pp. 865-875
    • Capela, A.1    Temple, S.2
  • 11
    • 0021220717 scopus 로고
    • Age at treatment and long-term performance results in medulloblastoma
    • Chin H.W., Maruyama Y. Age at treatment and long-term performance results in medulloblastoma. Cancer 1984, 53:1952.
    • (1984) Cancer , vol.53 , pp. 1952
    • Chin, H.W.1    Maruyama, Y.2
  • 13
    • 0028356814 scopus 로고
    • Neurobehavioral sequelae of cranial irradiation in adults: a review of radiation-induced encephalopathy
    • Crossen J.R., Garwood D., Glatstein E., Neuwelt E.A. Neurobehavioral sequelae of cranial irradiation in adults: a review of radiation-induced encephalopathy. J. Clin. Oncol. 1994, 12:627-642.
    • (1994) J. Clin. Oncol. , vol.12 , pp. 627-642
    • Crossen, J.R.1    Garwood, D.2    Glatstein, E.3    Neuwelt, E.A.4
  • 14
    • 0033040497 scopus 로고    scopus 로고
    • Subventricular zone astrocytes are neural stem cells in the adult mammalian brain
    • Doetsch F., Caille I., Lim D.A., Garcia-Verdugo J.M., Alvarez-Buylla A. Subventricular zone astrocytes are neural stem cells in the adult mammalian brain. Cell 1999, 97:703-716.
    • (1999) Cell , vol.97 , pp. 703-716
    • Doetsch, F.1    Caille, I.2    Lim, D.A.3    Garcia-Verdugo, J.M.4    Alvarez-Buylla, A.5
  • 16
    • 59349110661 scopus 로고    scopus 로고
    • Brain inflammation and adult neurogenesis: the dual role of microglia
    • Ekdahl C.T., Kokaia Z., Lindvall O. Brain inflammation and adult neurogenesis: the dual role of microglia. Neuroscience 2009, 158:1021-1029.
    • (2009) Neuroscience , vol.158 , pp. 1021-1029
    • Ekdahl, C.T.1    Kokaia, Z.2    Lindvall, O.3
  • 17
    • 0034305621 scopus 로고    scopus 로고
    • Glial fibrillary acidic protein: GFAP-thirty-one years (1969-2000)
    • Eng L.F., Ghirnikar R.S., Lee Y.L. Glial fibrillary acidic protein: GFAP-thirty-one years (1969-2000). Neurochem. Res. 2000, 25:1439-1451.
    • (2000) Neurochem. Res. , vol.25 , pp. 1439-1451
    • Eng, L.F.1    Ghirnikar, R.S.2    Lee, Y.L.3
  • 18
    • 33847217663 scopus 로고    scopus 로고
    • Cyclooxygenase-2 mediates the sensitizing effects of systemic IL-1-beta on excitotoxic brain lesions in newborn mice
    • Favrais G., Schwendimann L., Gressens P., Lelievre V. Cyclooxygenase-2 mediates the sensitizing effects of systemic IL-1-beta on excitotoxic brain lesions in newborn mice. Neurobiol. Dis. 2007, 25:496-505.
    • (2007) Neurobiol. Dis. , vol.25 , pp. 496-505
    • Favrais, G.1    Schwendimann, L.2    Gressens, P.3    Lelievre, V.4
  • 19
    • 0029002865 scopus 로고
    • Amoeboid microglial response following X-ray-induced apoptosis in the neonatal rat brain
    • Ferrer I., Olive M., Blanco R., Ballabriga J., Cinos C., Planas A.M. Amoeboid microglial response following X-ray-induced apoptosis in the neonatal rat brain. Neurosci. Lett. 1995, 193:109-112.
    • (1995) Neurosci. Lett. , vol.193 , pp. 109-112
    • Ferrer, I.1    Olive, M.2    Blanco, R.3    Ballabriga, J.4    Cinos, C.5    Planas, A.M.6
  • 20
    • 13244255516 scopus 로고    scopus 로고
    • Age-dependent sensitivity of the developing brain to irradiation is correlated with the number and vulnerability of progenitor cells
    • Fukuda A., Fukuda H., Swanpalmer J., Hertzman S., Lannering B., Marky I., Bjork-Eriksson T., Blomgren K. Age-dependent sensitivity of the developing brain to irradiation is correlated with the number and vulnerability of progenitor cells. J. Neurochem. 2005, 92:569-584.
    • (2005) J. Neurochem. , vol.92 , pp. 569-584
    • Fukuda, A.1    Fukuda, H.2    Swanpalmer, J.3    Hertzman, S.4    Lannering, B.5    Marky, I.6    Bjork-Eriksson, T.7    Blomgren, K.8
  • 21
    • 0031425302 scopus 로고    scopus 로고
    • Microglial cytokine gene induction after irradiation is affected by morphologic differentiation
    • Hayakawa K., Borchardt P.E., Sakuma S., Ijichi A., Niibe H., Tofilon P.J. Microglial cytokine gene induction after irradiation is affected by morphologic differentiation. Radiat. Med. 1997, 15:405-410.
    • (1997) Radiat. Med. , vol.15 , pp. 405-410
    • Hayakawa, K.1    Borchardt, P.E.2    Sakuma, S.3    Ijichi, A.4    Niibe, H.5    Tofilon, P.J.6
  • 22
    • 65249116981 scopus 로고    scopus 로고
    • Differential recovery of neural stem cells in the subventricular zone and dentate gyrus after ionizing radiation
    • Hellström N.A., Björk-Eriksson T., Blomgren K., Kuhn H.G. Differential recovery of neural stem cells in the subventricular zone and dentate gyrus after ionizing radiation. Stem Cells 2009, 27:634-641.
    • (2009) Stem Cells , vol.27 , pp. 634-641
    • Hellström, N.A.1    Björk-Eriksson, T.2    Blomgren, K.3    Kuhn, H.G.4
  • 23
    • 37049011249 scopus 로고    scopus 로고
    • Rapid quantification of neurons and stem/progenitor cells in the adult mouse brain by flow cytometry
    • Hellström N.A., Zachrisson O., Kuhn H.G., Patrone C. Rapid quantification of neurons and stem/progenitor cells in the adult mouse brain by flow cytometry. Lett. Drug Des. Discovery 2007, 4:532-539.
    • (2007) Lett. Drug Des. Discovery , vol.4 , pp. 532-539
    • Hellström, N.A.1    Zachrisson, O.2    Kuhn, H.G.3    Patrone, C.4
  • 24
    • 0036336528 scopus 로고    scopus 로고
    • Neural stem cell lineages are regionally specified, but not committed, within distinct compartments of the developing brain
    • Hitoshi S., Tropepe V., Ekker M., van der Kooy D. Neural stem cell lineages are regionally specified, but not committed, within distinct compartments of the developing brain. Development 2002, 129:233-244.
    • (2002) Development , vol.129 , pp. 233-244
    • Hitoshi, S.1    Tropepe, V.2    Ekker, M.3    van der Kooy, D.4
  • 25
    • 50649085986 scopus 로고    scopus 로고
    • Hes genes and neurogenin regulate non-neural versus neural fate specification in the dorsal telencephalic midline
    • Imayoshi I., Shimogori T., Ohtsuka T., Kageyama R. Hes genes and neurogenin regulate non-neural versus neural fate specification in the dorsal telencephalic midline. Development 2008, 135:2531-2541.
    • (2008) Development , vol.135 , pp. 2531-2541
    • Imayoshi, I.1    Shimogori, T.2    Ohtsuka, T.3    Kageyama, R.4
  • 30
    • 0035093737 scopus 로고    scopus 로고
    • DNA double-strand breaks: signaling, repair and the cancer connection
    • Khanna K.K., Jackson S.P. DNA double-strand breaks: signaling, repair and the cancer connection. Nat. Genet. 2001, 27:247-254.
    • (2001) Nat. Genet. , vol.27 , pp. 247-254
    • Khanna, K.K.1    Jackson, S.P.2
  • 31
    • 5644269242 scopus 로고    scopus 로고
    • Sox-2 is expressed by neural progenitors and astroglia in the adult rat brain
    • Komitova M., Eriksson P.S. Sox-2 is expressed by neural progenitors and astroglia in the adult rat brain. Neurosci. Lett. 2004, 369:24-27.
    • (2004) Neurosci. Lett. , vol.369 , pp. 24-27
    • Komitova, M.1    Eriksson, P.S.2
  • 32
    • 0029863342 scopus 로고    scopus 로고
    • Neurogenesis in the dentate gyrus of the adult rat: age-related decrease of neuronal progenitor proliferation
    • Kuhn H.G., Dickinson-Anson H., Gage F.H. Neurogenesis in the dentate gyrus of the adult rat: age-related decrease of neuronal progenitor proliferation. J. Neurosci. 1996, 16:2027-2033.
    • (1996) J. Neurosci. , vol.16 , pp. 2027-2033
    • Kuhn, H.G.1    Dickinson-Anson, H.2    Gage, F.H.3
  • 34
    • 38049090832 scopus 로고    scopus 로고
    • Cross-talk between the epidermal growth factor-like repeats/fibronectin 6-8 repeats domains of Tenascin-R and microglia modulates neural stem/progenitor cell proliferation and differentiation
    • Liao H., Huang W., Niu R., Sun L., Zhang L. Cross-talk between the epidermal growth factor-like repeats/fibronectin 6-8 repeats domains of Tenascin-R and microglia modulates neural stem/progenitor cell proliferation and differentiation. J. Neurosci. Res. 2008, 86:27-34.
    • (2008) J. Neurosci. Res. , vol.86 , pp. 27-34
    • Liao, H.1    Huang, W.2    Niu, R.3    Sun, L.4    Zhang, L.5
  • 35
    • 0027343619 scopus 로고
    • The origin and nature of ramified and amoeboid microglia: a historical review and current concepts
    • Ling E.A., Wong W.C. The origin and nature of ramified and amoeboid microglia: a historical review and current concepts. Glia 1993, 7:9-18.
    • (1993) Glia , vol.7 , pp. 9-18
    • Ling, E.A.1    Wong, W.C.2
  • 36
    • 0035710746 scopus 로고    scopus 로고
    • Analysis of relative gene expression data using real-time quantitative PCR and the 2(-Delta Delta C(T)) Method
    • Livak K.J., Schmittgen T.D. Analysis of relative gene expression data using real-time quantitative PCR and the 2(-Delta Delta C(T)) Method. Methods 2001, 25:402-408.
    • (2001) Methods , vol.25 , pp. 402-408
    • Livak, K.J.1    Schmittgen, T.D.2
  • 37
    • 77955368742 scopus 로고    scopus 로고
    • Quiescent and active hippocampal neural stem cells with distinct morphologies respond selectively to physiological and pathological stimuli and aging
    • Lugert S., Basak O., Knuckles P., Haussler U., Fabel K., Gotz M., Haas C.A., Kempermann G., Taylor V., Giachino C. Quiescent and active hippocampal neural stem cells with distinct morphologies respond selectively to physiological and pathological stimuli and aging. Cell Stem Cell 2010, 6:445-456.
    • (2010) Cell Stem Cell , vol.6 , pp. 445-456
    • Lugert, S.1    Basak, O.2    Knuckles, P.3    Haussler, U.4    Fabel, K.5    Gotz, M.6    Haas, C.A.7    Kempermann, G.8    Taylor, V.9    Giachino, C.10
  • 38
    • 25844458514 scopus 로고    scopus 로고
    • Glial influences on neural stem cell development: cellular niches for adult neurogenesis
    • Ma D.K., Ming G.L., Song H. Glial influences on neural stem cell development: cellular niches for adult neurogenesis. Curr. Opin. Neurobiol. 2005, 15:514-520.
    • (2005) Curr. Opin. Neurobiol. , vol.15 , pp. 514-520
    • Ma, D.K.1    Ming, G.L.2    Song, H.3
  • 39
    • 0038182466 scopus 로고    scopus 로고
    • Arrested neuronal proliferation and impaired hippocampal function following fractionated brain irradiation in the adult rat
    • Madsen T.M., Kristjansen P.E., Bolwig T.G., Wortwein G. Arrested neuronal proliferation and impaired hippocampal function following fractionated brain irradiation in the adult rat. Neuroscience 2003, 119:635-642.
    • (2003) Neuroscience , vol.119 , pp. 635-642
    • Madsen, T.M.1    Kristjansen, P.E.2    Bolwig, T.G.3    Wortwein, G.4
  • 41
    • 0036735783 scopus 로고    scopus 로고
    • Irradiation induces neural precursor-cell dysfunction
    • Monje M.L., Mizumatsu S., Fike J.R., Palmer T.D. Irradiation induces neural precursor-cell dysfunction. Nat. Med. 2002, 8:955-962.
    • (2002) Nat. Med. , vol.8 , pp. 955-962
    • Monje, M.L.1    Mizumatsu, S.2    Fike, J.R.3    Palmer, T.D.4
  • 42
    • 0345189366 scopus 로고    scopus 로고
    • Inflammatory blockade restores adult hippocampal neurogenesis
    • Monje M.L., Toda H., Palmer T.D. Inflammatory blockade restores adult hippocampal neurogenesis. Science 2003.
    • (2003) Science
    • Monje, M.L.1    Toda, H.2    Palmer, T.D.3
  • 43
    • 37349127393 scopus 로고    scopus 로고
    • Impaired human hippocampal neurogenesis after treatment for central nervous system malignancies
    • Monje M.L., Vogel H., Masek M., Ligon K.L., Fisher P.G., Palmer T.D. Impaired human hippocampal neurogenesis after treatment for central nervous system malignancies. Ann. Neurol. 2007, 62:515-520.
    • (2007) Ann. Neurol. , vol.62 , pp. 515-520
    • Monje, M.L.1    Vogel, H.2    Masek, M.3    Ligon, K.L.4    Fisher, P.G.5    Palmer, T.D.6
  • 44
    • 33847643776 scopus 로고    scopus 로고
    • Quantification of mRNA using real-time RT-PCR
    • Nolan T., Hands R.E., Bustin S.A. Quantification of mRNA using real-time RT-PCR. Nat. Protoc. 2006, 1:1559-1582.
    • (2006) Nat. Protoc. , vol.1 , pp. 1559-1582
    • Nolan, T.1    Hands, R.E.2    Bustin, S.A.3
  • 45
    • 0033216122 scopus 로고    scopus 로고
    • Fibroblast growth factor-2 activates a latent neurogenic program in neural stem cells from diverse regions of the adult CNS
    • Palmer T.D., Markakis E.A., Willhoite A.R., Safar F., Gage F.H. Fibroblast growth factor-2 activates a latent neurogenic program in neural stem cells from diverse regions of the adult CNS. J. Neurosci. 1999, 19:8487-8497.
    • (1999) J. Neurosci. , vol.19 , pp. 8487-8497
    • Palmer, T.D.1    Markakis, E.A.2    Willhoite, A.R.3    Safar, F.4    Gage, F.H.5
  • 46
    • 0034597430 scopus 로고    scopus 로고
    • Vascular niche for adult hippocampal neurogenesis
    • Palmer T.D., Willhoite A.R., Gage F.H. Vascular niche for adult hippocampal neurogenesis. J. Comp. Neurol. 2000, 425:479-494.
    • (2000) J. Comp. Neurol. , vol.425 , pp. 479-494
    • Palmer, T.D.1    Willhoite, A.R.2    Gage, F.H.3
  • 47
    • 53149138204 scopus 로고    scopus 로고
    • Mechanisms of platelet-derived growth factor-mediated neuroprotection-implications in HIV dementia
    • Peng F., Dhillon N.K., Yao H., Zhu X., Williams R., Buch S. Mechanisms of platelet-derived growth factor-mediated neuroprotection-implications in HIV dementia. Eur. J. Neurosci. 2008, 28:1255-1264.
    • (2008) Eur. J. Neurosci. , vol.28 , pp. 1255-1264
    • Peng, F.1    Dhillon, N.K.2    Yao, H.3    Zhu, X.4    Williams, R.5    Buch, S.6
  • 48
    • 3042799716 scopus 로고    scopus 로고
    • Radiation-induced impairment of hippocampal neurogenesis is associated with cognitive deficits in young mice
    • Rola R., Raber J., Rizk A., Otsuka S., VandenBerg S.R., Morhardt D.R., Fike J.R. Radiation-induced impairment of hippocampal neurogenesis is associated with cognitive deficits in young mice. Exp. Neurol. 2004, 188:316-330.
    • (2004) Exp. Neurol. , vol.188 , pp. 316-330
    • Rola, R.1    Raber, J.2    Rizk, A.3    Otsuka, S.4    VandenBerg, S.R.5    Morhardt, D.R.6    Fike, J.R.7
  • 49
    • 0037968010 scopus 로고    scopus 로고
    • Basic helix-loop-helix factors in cortical development
    • Ross S.E., Greenberg M.E., Stiles C.D. Basic helix-loop-helix factors in cortical development. Neuron 2003, 39:13-25.
    • (2003) Neuron , vol.39 , pp. 13-25
    • Ross, S.E.1    Greenberg, M.E.2    Stiles, C.D.3
  • 50
    • 0036522968 scopus 로고    scopus 로고
    • Adult rodent neurogenic regions: the ventricular subependyma contains neural stem cells, but the dentate gyrus contains restricted progenitors
    • Seaberg R.M., van der Kooy D. Adult rodent neurogenic regions: the ventricular subependyma contains neural stem cells, but the dentate gyrus contains restricted progenitors. J. Neurosci. 2002, 22:1784-1793.
    • (2002) J. Neurosci. , vol.22 , pp. 1784-1793
    • Seaberg, R.M.1    van der Kooy, D.2
  • 51
    • 0024245022 scopus 로고
    • Inhibition of pluripotential embryonic stem cell differentiation by purified polypeptides
    • Smith A.G., Heath J.K., Donaldson D.D., Wong G.G., Moreau J., Stahl M., Rogers D. Inhibition of pluripotential embryonic stem cell differentiation by purified polypeptides. Nature 1988, 336:688-690.
    • (1988) Nature , vol.336 , pp. 688-690
    • Smith, A.G.1    Heath, J.K.2    Donaldson, D.D.3    Wong, G.G.4    Moreau, J.5    Stahl, M.6    Rogers, D.7
  • 52
    • 42549086336 scopus 로고    scopus 로고
    • Multiway real-time PCR gene expression profiling in yeast Saccharomyces cerevisiae reveals altered transcriptional response of ADH-genes to glucose stimuli
    • Stahlberg A., Elbing K., Andrade-Garda J.M., Sjogreen B., Forootan A., Kubista M. Multiway real-time PCR gene expression profiling in yeast Saccharomyces cerevisiae reveals altered transcriptional response of ADH-genes to glucose stimuli. BMC Genomics 2008, 9:170.
    • (2008) BMC Genomics , vol.9 , pp. 170
    • Stahlberg, A.1    Elbing, K.2    Andrade-Garda, J.M.3    Sjogreen, B.4    Forootan, A.5    Kubista, M.6
  • 53
    • 33750550909 scopus 로고    scopus 로고
    • Type-2 cells as link between glial and neuronal lineage in adult hippocampal neurogenesis
    • Steiner B., Klempin F., Wang L., Kott M., Kettenmann H., Kempermann G. Type-2 cells as link between glial and neuronal lineage in adult hippocampal neurogenesis. Glia 2006, 54:805-814.
    • (2006) Glia , vol.54 , pp. 805-814
    • Steiner, B.1    Klempin, F.2    Wang, L.3    Kott, M.4    Kettenmann, H.5    Kempermann, G.6
  • 55
    • 0034718139 scopus 로고    scopus 로고
    • X-irradiation causes a prolonged reduction in cell proliferation in the dentate gyrus of adult rats
    • Tada E., Parent J.M., Lowenstein D.H., Fike J.R. X-irradiation causes a prolonged reduction in cell proliferation in the dentate gyrus of adult rats. Neuroscience 2000, 99:33-41.
    • (2000) Neuroscience , vol.99 , pp. 33-41
    • Tada, E.1    Parent, J.M.2    Lowenstein, D.H.3    Fike, J.R.4
  • 58
    • 1642445643 scopus 로고    scopus 로고
    • Distinct neural stem cells proliferate in response to EGF and FGF in the developing mouse telencephalon
    • Tropepe V., Sibilia M., Ciruna B.G., Rossant J., Wagner E.F., van der Kooy D. Distinct neural stem cells proliferate in response to EGF and FGF in the developing mouse telencephalon. Dev. Biol. 1999, 208:166-188.
    • (1999) Dev. Biol. , vol.208 , pp. 166-188
    • Tropepe, V.1    Sibilia, M.2    Ciruna, B.G.3    Rossant, J.4    Wagner, E.F.5    van der Kooy, D.6
  • 60
    • 0037129827 scopus 로고    scopus 로고
    • Accurate normalization of real-time quantitative RT-PCR data by geometric averaging of multiple internal control genes
    • RESEARCH0034
    • Vandesompele J., De Preter K., Pattyn F., Poppe B., Van Roy N., De Paepe A., Speleman F. Accurate normalization of real-time quantitative RT-PCR data by geometric averaging of multiple internal control genes. Genome Biol. 2002, 3. RESEARCH0034.
    • (2002) Genome Biol. , vol.3
    • Vandesompele, J.1    De Preter, K.2    Pattyn, F.3    Poppe, B.4    Van Roy, N.5    De Paepe, A.6    Speleman, F.7
  • 64
    • 33748358798 scopus 로고    scopus 로고
    • Synergy between immune cells and adult neural stem/progenitor cells promotes functional recovery from spinal cord injury
    • Ziv Y., Avidan H., Pluchino S., Martino G., Schwartz M. Synergy between immune cells and adult neural stem/progenitor cells promotes functional recovery from spinal cord injury. Proc. Natl Acad. Sci. USA 2006, 103:13174-13179.
    • (2006) Proc. Natl Acad. Sci. USA , vol.103 , pp. 13174-13179
    • Ziv, Y.1    Avidan, H.2    Pluchino, S.3    Martino, G.4    Schwartz, M.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.