SMRT recruitment by PPARγ is mediated by specific residues located in its carboxy-terminal interacting domain (DOI:10.1016/j.mce.2006.08.004);SMRT recruitment by PPARγ is mediated by specific residues located in its carboxy-terminal interacting domain

Molecular and Cellular Endocrinology

Volumn 259, Issue 1-2, 2006, Pages 43-49

  Sutanto, Maria M ^a   Symons, Melissa S ^a   Cohen, Ronald N ^a  

^a UNIVERSITY OF CHICAGO   (United States)

Author keywords

Adipogenesis; Corepressors; Peroxisome proliferator activated receptor; Silencing mediator of retinoid and thyroid hormone receptors; Transcriptional regulation

Indexed keywords

PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA; RECEPTOR; SILENCING MEDIATOR OF RETINOID AND THYROID RECEPTOR; UNCLASSIFIED DRUG; ISOPROTEIN; MUTANT PROTEIN; REPRESSOR PROTEIN; RETINOIC ACID RECEPTOR; RETINOIC ACID RECEPTOR ALPHA; RETINOID X RECEPTOR; SMRT PROTEIN, XENOPUS; XENOPUS PROTEIN;

ANIMAL CELL; ARTICLE; CARBOXY TERMINAL SEQUENCE; CONTROLLED STUDY; MUTATION; NONHUMAN; PRIORITY JOURNAL; PROTEIN DOMAIN; RAT; ANIMAL; CELL STRAIN 3T3; CERCOPITHECUS; CHEMICAL STRUCTURE; CHEMISTRY; DIMERIZATION; METABOLISM; MOUSE; PHYSIOLOGY; PROTEIN BINDING; PROTEIN TERTIARY STRUCTURE; TRANSACTIVATION;

3T3-L1 CELLS; ANIMALS; CERCOPITHECUS AETHIOPS; DIMERIZATION; MICE; MODELS, MOLECULAR; MUTANT PROTEINS; MUTATION; PPAR GAMMA; PROTEIN BINDING; PROTEIN ISOFORMS; PROTEIN STRUCTURE, TERTIARY; RECEPTORS, RETINOIC ACID; REPRESSOR PROTEINS; RETINOID X RECEPTORS; TRANS-ACTIVATION (GENETICS); XENOPUS PROTEINS;

EID: 33748792281     PISSN: 03037207     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.mce.2006.10.015     Document Type: Erratum

References (21)

1. Auwerx J. Nuclear receptors. I. PPAR gamma in the gastrointestinal tract: gain or pain?. Am. J. Physiol. Gastrointest. Liver Physiol. 282 (2002) G581-G585
2. Chen J.D., and Evans R.M. A transcriptional co-repressor that interacts with nuclear hormone receptors. Nature 377 (1995) 454-457
3. Cohen R.N. Nuclear receptor corepressors and PPARgamma. Nucl. Recept. Signal 4 (2006) e003
4. Cohen R.N., Brzostek S., Kim B., Chorev M., Wondisford F.E., and Hollenberg A.N. The specificity of interactions between nuclear hormone receptors and corepressors is mediated by distinct amino acid sequences within the interacting domains. Mol. Endocrinol. 15 (2001) 1049-1061
5. Cohen R.N., Putney A., Wondisford F.E., and Hollenberg A.N. The nuclear corepressors recognize distinct nuclear receptor complexes. Mol. Endocrinol. 14 (2000) 900-914
6. Goodson M.L., Jonas B.A., and Privalsky M.L. Alternative mRNA splicing of SMRT creates functional diversity by generating corepressor isoforms with different affinities for different nuclear receptors. J. Biol. Chem. 280 (2005) 7493-7503
7. Guan H.P., Ishizuka T., Chui P.C., Lehrke M., and Lazar M.A. Corepressors selectively control the transcriptional activity of PPARgamma in adipocytes. Gene Dev. 19 (2005) 453-461
8. Hauksdottir H., Farboud B., and Privalsky M.L. Retinoic acid receptors beta and gamma do not repress, but instead activate target gene transcription in both the absence and presence of hormone ligand. Mol. Endocrinol. 17 (2003) 373-385
9. Hevener A.L., He W., Barak Y., Le J., Bandyopadhyay G., Olson P., Wilkes J., Evans R.M., and Olefsky J. Muscle-specific Pparg deletion causes insulin resistance. Nat. Med. 9 (2003) 1491-1497
10. Horlein A.J., Naar A.M., Heinzel T., Torchia J., Gloss B., Kurokawa R., Ryan A., Kamei Y., Soderstrom M., Glass C.K., and Rosenfeld M.G. Ligand-independent repression by the thyroid hormone receptor mediated by a nuclear receptor co-repressor. Nature 377 (1995) 397-404
11. Hu X., and Lazar M.A. The CoRNR motif controls the recruitment of corepressors by nuclear hormone receptors. Nature 402 (1999) 93-96
12. Lehrke M., and Lazar M.A. The many faces of PPARgamma. Cell 123 (2005) 993-999
13. Mangelsdorf D.J., Thummel C., Beato M., Herrlich P., Schutz G., Umesono K., Blumberg B., Kastner P., Mark M., Chambon P., and Evans R.M. The nuclear receptor superfamily: the second decade. Cell 83 (1995) 835-839
14. Matsusue K., Haluzik M., Lambert G., Yim S.H., Gavrilova O., Ward J.M., Brewer Jr. B., Reitman M.L., and Gonzalez F.J. Liver-specific disruption of PPARgamma in leptin-deficient mice improves fatty liver but aggravates diabetic phenotypes. J. Clin. Invest. 111 (2003) 737-747
15. Nagy L., Kao H.Y., Love J.D., Li C., Banayo E., Gooch J.T., Krishna V., Chatterjee K., Evans R.M., and Schwabe J.W. Mechanism of corepressor binding and release from nuclear hormone receptors. Gene Dev. 13 (1999) 3209-3216
16. Norris A.W., Chen L., Fisher S.J., Szanto I., Ristow M., Jozsi A.C., Hirshman M.F., Rosen E.D., Goodyear L.J., Gonzalez F.J., et al. Muscle-specific PPARgamma-deficient mice develop increased adiposity and insulin resistance but respond to thiazolidinediones. J. Clin. Invest. 112 (2003) 608-618
17. Pascual G., Fong A.L., Ogawa S., Gamliel A., Li A.C., Perissi V., Rose D.W., Willson T.M., Rosenfeld M.G., and Glass C.K. A SUMOylation-dependent pathway mediates transrepression of inflammatory response genes by PPAR-gamma. Nature 437 (2005) 759-763
18. Perissi V., Staszewski L.M., McInerney E.M., Kurokawa R., Krones A., Rose D.W., Lambert M.H., Milburn M.V., Glass C.K., and Rosenfeld M.G. Molecular determinants of nuclear receptor-corepressor interaction. Gene Dev. 13 (1999) 3198-3208
19. Privalsky M.L. The role of corepressors in transcriptional regulation by nuclear hormone receptors. Annu. Rev. Physiol. 66 (2004) 315-360
20. Xu H.E., Stanley T.B., Montana V.G., Lambert M.H., Shearer B.G., Cobb J.E., McKee D.D., Galardi C.M., Plunket K.D., Nolte R.T., et al. Structural basis for antagonist-mediated recruitment of nuclear co-repressors by PPARalpha. Nature 415 (2002) 813-817
21. Yu C., Markan K., Temple K.A., Deplewski D., Brady M.J., and Cohen R.N. The nuclear receptor corepressors NCoR and SMRT decrease peroxisome proliferator-activated receptor gamma transcriptional activity and repress 3T3-L1 adipogenesis. J. Biol. Chem. 280 (2005) 13600-13605