메뉴 건너뛰기




Volumn 48, Issue 1, 2011, Pages 7-13

MsbA ATP-binding cassette (ABC) transporter of E. coli: Structure and possible flippase mechanism

Author keywords

ATP hydrolysis; ATP binding cassette transporter; E. coli; Flip flop; MsbA; Structure

Indexed keywords

ABC TRANSPORTER; ADENOSINE TRIPHOSPHATE; BACTERIAL PROTEIN; CARRIER PROTEIN; MSBA PROTEIN, BACTERIA; PHOSPHOLIPID TRANSFER PROTEIN;

EID: 79952958606     PISSN: 03011208     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Review
Times cited : (9)

References (51)
  • 1
    • 0347479229 scopus 로고    scopus 로고
    • Molecular basis of bacterial outer membrane permeability revisited
    • Nikaido H (2003) Molecular basis of bacterial outer membrane permeability revisited. Microbiol Mol Biol Rev 67, 593-656
    • (2003) Microbiol Mol Biol Rev , vol.67 , pp. 593-656
    • Nikaido, H.1
  • 2
    • 33645836299 scopus 로고    scopus 로고
    • Lipid trafficking to the outer membrane of Gram-negative bacteria
    • Doerrier W T (2006) Lipid trafficking to the outer membrane of Gram-negative bacteria. Mol Microbiol 60, 542-552
    • (2006) Mol Microbiol , vol.60 , pp. 542-552
    • Doerrier, W.T.1
  • 3
    • 1642384019 scopus 로고    scopus 로고
    • Innate recognition of lipopolysaccharide by Toll-like receptor 4-MD-2
    • Miyake K (2004) Innate recognition of lipopolysaccharide by Toll-like receptor 4-MD-2. Trends Microbiol 12, 186-192
    • (2004) Trends Microbiol , vol.12 , pp. 186-192
    • Miyake, K.1
  • 4
    • 44949249999 scopus 로고    scopus 로고
    • Structure, function, and evolution of bacterial ATP-binding cassette systems
    • Davidson A L, Dassa E, Orelle C and amp; Chen J (2008) Structure, function, and evolution of bacterial ATP-binding cassette systems. Microbiol Mol Biol Rev 72, 317-364
    • (2008) Microbiol Mol Biol Rev , vol.72 , pp. 317-364
    • Davidson, A.L.1    Dassa, E.2    Orelle, C.3    Chen, J.4
  • 6
    • 70349785154 scopus 로고    scopus 로고
    • Alternating Access of the Putative Substrate-Binding Chamber in the ABC Transporter MsbA
    • Zou P & Mchaourab S H (2009) Alternating Access of the Putative Substrate-Binding Chamber in the ABC Transporter MsbA. J Mol Biol 393, 574-585
    • (2009) J Mol Biol , vol.393 , pp. 574-585
    • Zou, P.1    McHaourab, S.H.2
  • 7
    • 0242478028 scopus 로고    scopus 로고
    • Protein secretion by Gram-negative bacterial ABC exporters - a review
    • Binet R, Letoffe S, Ghigo J M, Delepelaire P & Wandersman C (1997) Protein secretion by Gram-negative bacterial ABC exporters - a review. Gene 192, 7-11
    • (1997) Gene , vol.192 , pp. 7-11
    • Binet, R.1    Letoffe, S.2    Ghigo, J.M.3    Delepelaire, P.4    Wandersman, C.5
  • 8
    • 0036789902 scopus 로고    scopus 로고
    • Mechanism of ABC transporters: A molecular dynamics simulation of a well characterized nucleotide-binding subunit
    • Jones P M & George A M, (2002) Mechanism of ABC transporters: A molecular dynamics simulation of a well characterized nucleotide-binding subunit. Proc Natl Acad Sci (USA) 99, 12639-12644
    • (2002) Proc Natl Acad Sci (USA) , vol.99 , pp. 12639-12644
    • Jones, P.M.1    George, A.M.2
  • 9
    • 0033534178 scopus 로고    scopus 로고
    • The purified and functionally reconstituted multidrug transporter LmrA of Lactococcus lactis mediates the transbilayer movement of specific fluorescent phospholipids
    • Margolles A, Putman M, van Veen, H W & Konings, W N (1999) The purified and functionally reconstituted multidrug transporter LmrA of Lactococcus lactis mediates the transbilayer movement of specific fluorescent phospholipids. Biochemistry 38, 16298-16306
    • (1999) Biochemistry , vol.38 , pp. 16298-16306
    • Margolles, A.1    Putman, M.2    van Veen, H.W.3    Konings, W.N.4
  • 11
    • 0031943304 scopus 로고    scopus 로고
    • The Escherichia Coli ATP-binding Cassette (ABC) Proteins
    • Linton K J & Higgins C F (1998) The Escherichia coli ATP-binding cassette (ABC) proteins. Mol Microbiol 28, 5-13
    • (1998) Mol Microbiol , vol.28 , pp. 5-13
    • Linton, K.J.1    Higgins, C.F.2
  • 12
    • 70349312287 scopus 로고    scopus 로고
    • The ATP-binding cassette family: A structural perspective
    • Kos V & Ford R C (2009) The ATP-binding cassette family: A structural perspective. Cell Mol Life Sci 66, 3111-3126
    • (2009) Cell Mol Life Sci , vol.66 , pp. 3111-3126
    • Kos, V.1    Ford, R.C.2
  • 13
    • 33646557693 scopus 로고    scopus 로고
    • Nucleotide binding domain interactions during the mechanochemical reaction cycle of ATP-binding cassette transporters
    • Moody J E & Thomas P J (2005) Nucleotide binding domain interactions during the mechanochemical reaction cycle of ATP-binding cassette transporters. J Bioenerg Biomembr 37, 475-479.
    • (2005) J Bioenerg Biomembr , vol.37 , pp. 475-479
    • Moody, J.E.1    Thomas, P.J.2
  • 14
    • 3943062954 scopus 로고    scopus 로고
    • ATP-Binding cassette transporters in bacteria
    • Davidson A L & Chen J (2004) ATP-Binding cassette transporters in bacteria. Ann Rev Biochem 73, 241-268
    • (2004) Ann Rev Biochem , vol.73 , pp. 241-268
    • Davidson, A.L.1    Chen, J.2
  • 15
    • 0026053770 scopus 로고
    • Structural model of the nucleotide-binding conserved component of periplasmic permeases
    • Mimura C S, Holbrook S R & Ames G F (1991) Structural model of the nucleotide-binding conserved component of periplasmic permeases. Proc Natl Acad Sci (USA) 88, 84-88
    • (1991) Proc Natl Acad Sci (USA) , vol.88 , pp. 84-88
    • Mimura, C.S.1    Holbrook, S.R.2    Ames, G.F.3
  • 18
    • 0033511228 scopus 로고    scopus 로고
    • Nucleoside triphosphate-binding proteins: Different scaffolds to achieve phosphoryl transfer
    • Vetter I R & Wittinghofer A (1999) Nucleoside triphosphate-binding proteins: different scaffolds to achieve phosphoryl transfer. Q Rev Biophys 32, 1-56
    • (1999) Q Rev Biophys , vol.32 , pp. 1-56
    • Vetter, I.R.1    Wittinghofer, A.2
  • 19
    • 0001607723 scopus 로고
    • Distantly related sequences in the alpha- and beta-subunits of ATP synthase, myosin, kinases and other ATPrequiring enzymes and a common nucleotide binding fold
    • Walker J E, Saraste M, Runswick M J, & Gay N J (1982) Distantly related sequences in the alpha- and beta-subunits of ATP synthase, myosin, kinases and other ATPrequiring enzymes and a common nucleotide binding fold. EMBO J 1, 945-951
    • (1982) EMBO J , vol.1 , pp. 945-951
    • Walker, J.E.1    Saraste, M.2    Runswick, M.J.3    Gay, N.J.4
  • 20
    • 0037133735 scopus 로고    scopus 로고
    • Structure and association of ATP-binding cassette transporter nucleotide- binding domains
    • Kerr I D (2002) Structure and association of ATP-binding cassette transporter nucleotide- binding domains. Biochim Biophys Acta 1561, 47-64
    • (2002) Biochim Biophys Acta , vol.1561 , pp. 47-64
    • Kerr, I.D.1
  • 21
    • 0026584599 scopus 로고
    • Structure of the recA protein - ADP complex
    • Story R M & Steitz T A (1992) Structure of the recA protein - ADP complex. Nature 355, 374-376
    • (1992) Nature , vol.355 , pp. 374-376
    • Story, R.M.1    Steitz, T.A.2
  • 23
    • 0017363137 scopus 로고
    • Energy-coupling of the transport system of Escherichia coli Dependent on Maltose - Binding Protein
    • Ferenci T, Boos W, Schwartz M & Szmelcman S (1977) Energy-coupling of the transport system of Escherichia coli Dependent on Maltose - Binding Protein. Eur J Biochem 75, 187-193
    • (1977) Eur J Biochem , vol.75 , pp. 187-193
    • Ferenci, T.1    Boos, W.2    Schwartz, M.3    Szmelcman, S.4
  • 24
    • 33846521753 scopus 로고    scopus 로고
    • The Walker B motif of the second nucleotide- binding domain (NBD2) of the CFTR plays a key role in ATPase activity by the NBD1- NBD2 heterodimer
    • Stratford F L L, Ramjeesingh M, Cheung J A, Huan L J & Bear C E (2007) The Walker B motif of the second nucleotide- binding domain (NBD2) of the CFTR plays a key role in ATPase activity by the NBD1- NBD2 heterodimer. Biochem J 401, 581-586
    • (2007) Biochem J , vol.401 , pp. 581-586
    • Stratford, F.L.L.1    Ramjeesingh, M.2    Cheung, J.A.3    Huan, L.J.4    Bear, C.E.5
  • 25
    • 33750038243 scopus 로고    scopus 로고
    • Characterization of the LSGGQ and H motifs from the Escherichia coli lipid A transporter MsbA
    • Buchaklian A H & Klug G S (2006) Characterization of the LSGGQ and H motifs from the Escherichia coli lipid A transporter MsbA. Biochemistry 45, 12539-12546
    • (2006) Biochemistry , vol.45 , pp. 12539-12546
    • Buchaklian, A.H.1    Klug, G.S.2
  • 27
    • 16844381206 scopus 로고    scopus 로고
    • Characterization of the walker motif of MsbA using site-directed spin labeling electron paramagnetic resonance spectroscopy
    • Buchaklian A H & Klug C S (2005) Characterization of the walker motif of MsbA using site-directed spin labeling electron paramagnetic resonance spectroscopy. Biochemistry 44, 5503-5509
    • (2005) Biochemistry , vol.44 , pp. 5503-5509
    • Buchaklian, A.H.1    Klug, C.S.2
  • 28
    • 27744566698 scopus 로고    scopus 로고
    • MsbA is not required for phospholipids transport in Neisseria meningitides
    • Tefsen B, Bos, M P, Beckers F, Tommassen J & de Cock H (2005) MsbA is not required for phospholipids transport in Neisseria meningitides. J Biol Chem 280, 35961-35966
    • (2005) J Biol Chem , vol.280 , pp. 35961-35966
    • Tefsen, B.1    Bos, M.P.2    Beckers, F.3    Tommassen, J.4    de Cock, H.5
  • 30
    • 64249159261 scopus 로고    scopus 로고
    • The ABC transporter MsbA interacts with lipid A and amphipathic drugs at different sites
    • Siarheyeva A & Sharom, F J (2009) The ABC transporter MsbA interacts with lipid A and amphipathic drugs at different sites. Biochem J 419, 317-328
    • (2009) Biochem J , vol.419 , pp. 317-328
    • Siarheyeva, A.1    Sharom, F.J.2
  • 31
    • 79952918686 scopus 로고    scopus 로고
    • The E. coli BtuCDp-glycoprotein exhibits reduced affinity for substrate during structure: Framework for ABC transporter architecture anda catalytic transition state
    • Locher K P, Lee A T & Rus D G (2002) The E. coli BtuCDp-glycoprotein exhibits reduced affinity for substrate during structure: framework for ABC transporter architecture anda catalytic transition state. Biochemistry, 37, 5010-5019
    • (2002) Biochemistry , vol.37 , pp. 5010-5019
    • Locher, K.P.1    Lee, A.T.2    Rus, D.G.3
  • 32
  • 33
    • 37649004412 scopus 로고    scopus 로고
    • Flexibility in the ABC transporter MsbA: Alternating access with a twist
    • Ward A, Reyes C L, Yu J, Roth C B & Chang G (2007) Flexibility in the ABC transporter MsbA: alternating access with a twist. Proc Natl Acad Sci (USA) 104, 19005-19010
    • (2007) Proc Natl Acad Sci (USA) , vol.104 , pp. 19005-19010
    • Ward, A.1    Reyes, C.L.2    Yu, J.3    Roth, C.B.4    Chang, G.5
  • 35
    • 33847628162 scopus 로고    scopus 로고
    • Phospholipid Flippases
    • Daleke D L (2007) Phospholipid Flippases. J Biol Chem 282, 821-825
    • (2007) J Biol Chem , vol.282 , pp. 821-825
    • Daleke, D.L.1
  • 36
    • 0015514472 scopus 로고
    • The fluid mosaic model of the structure of cell membranes
    • Singer S J & Nicolson G L (1972) The fluid mosaic model of the structure of cell membranes. Science 175, 720-731
    • (1972) Science , vol.175 , pp. 720-731
    • Singer, S.J.1    Nicolson, G.L.2
  • 37
    • 0142218366 scopus 로고    scopus 로고
    • Regulation of transbilayer plasma membrane phospholipid asymmetry
    • Daleke D L (2003) Regulation of transbilayer plasma membrane phospholipid asymmetry. J Lipid Res 44, 233-242
    • (2003) J Lipid Res , vol.44 , pp. 233-242
    • Daleke, D.L.1
  • 38
    • 14644393694 scopus 로고    scopus 로고
    • Lipid traffic: Floppy drives and a superhighway
    • Holthuis J C & Levine T P (2005) Lipid traffic: floppy drives and a superhighway. Nat Rev Mol Cell Biol 6, 209-220
    • (2005) Nat Rev Mol Cell Biol , vol.6 , pp. 209-220
    • Holthuis, J.C.1    Levine, T.P.2
  • 39
    • 0037184103 scopus 로고    scopus 로고
    • ATPase activity of the MsbA lipid flippase of Escherichia coli
    • Doerrler W T & Raetz C R (2002) ATPase activity of the MsbA lipid flippase of Escherichia coli. J Biol Chem 277, 36697-36705
    • (2002) J Biol Chem , vol.277 , pp. 36697-36705
    • Doerrler, W.T.1    Raetz, C.R.2
  • 40
    • 45149113880 scopus 로고    scopus 로고
    • Functional characterization of Escherichia coli MsbA: Interaction with nucleotides and substrates
    • Eckford P D & Sharom F J (2008) Functional characterization of Escherichia coli MsbA: interaction with nucleotides and substrates. J Biol Chem 283, 12840-12850
    • (2008) J Biol Chem , vol.283 , pp. 12840-12850
    • Eckford, P.D.1    Sharom, F.J.2
  • 41
    • 77954470126 scopus 로고    scopus 로고
    • The reconstituted Escherichia coli MsbA protein displays lipid flippase activity
    • Eckford W D P & Sharom J F (2010) The reconstituted Escherichia coli MsbA protein displays lipid flippase activity. Biochem J 429, 195-203
    • (2010) Biochem J , vol.429 , pp. 195-203
    • Eckford, W.D.P.1    Sharom, J.F.2
  • 42
    • 0014029736 scopus 로고
    • Simple Allosteric model for membrane pumps
    • Jardetzky O (1966) Simple Allosteric model for membrane pumps. Nature 211, 969-970
    • (1966) Nature , vol.211 , pp. 969-970
    • Jardetzky, O.1
  • 45
    • 0037133616 scopus 로고    scopus 로고
    • Vanadate trapping of nucleotide at the ATP binding sites of human multidrug resistance p-glycoprotein exposes different residues to the drug binding site
    • Loo T W & Clarke D M (2002) Vanadate trapping of nucleotide at the ATP binding sites of human multidrug resistance p-glycoprotein exposes different residues to the drug binding site. Proc Natl Acad Sci (USA) 99, 3511-3516
    • (2002) Proc Natl Acad Sci (USA) , vol.99 , pp. 3511-3516
    • Loo, T.W.1    Clarke, D.M.2
  • 46
    • 77954613193 scopus 로고    scopus 로고
    • Asymmetric Switching in a Homodimeric ABC Transporter: A Simulation Study
    • doi:10.1371/journal.pcbi.1000762
    • Aittoniemi J, de Wet H, Ashcroft F M & Sansom M S P (2010) Asymmetric Switching in a Homodimeric ABC Transporter: A Simulation Study. PLoS Comput Biol 6(4). e1000762. doi:10.1371/journal.pcbi.1000762
    • (2010) PLoS Comput Biol , vol.6 , Issue.4
    • Aittoniemi, J.1    de Wet, H.2    Ashcroft, F.M.3    Sansom, M.S.P.4
  • 47
    • 77957280700 scopus 로고    scopus 로고
    • Helical crystallization of two example membrane proteins MsbA and the Ca(2+)-ATPase
    • Glaves J P, Fisher L, Ward A & Young H S (2010) Helical crystallization of two example membrane proteins MsbA and the Ca(2+)-ATPase. Methods Enzymol 483, 143-59.
    • (2010) Methods Enzymol , vol.483 , pp. 143-159
    • Glaves, J.P.1    Fisher, L.2    Ward, A.3    Young, H.S.4
  • 48
    • 77958007499 scopus 로고    scopus 로고
    • Dissection of the conformational cycle of the multidrug/lipidA ABC exporter MsbA
    • Doshi R, Woebking B & Van Veen H W (2010) Dissection of the conformational cycle of the multidrug/lipidA ABC exporter MsbA. Proteins 78, 2867-72.
    • (2010) Proteins , vol.78 , pp. 2867-2872
    • Doshi, R.1    Woebking, B.2    van Veen, H.W.3
  • 49
    • 77649168733 scopus 로고    scopus 로고
    • Deleting two C-terminal alphahelices is effective to crystallize the bacterial ABC transporter Escherichia coli MsbA complexed with AMPPNP
    • Terakado K, Kodan A, Nakano H, Kimura Y, Ueda K, Nakatsu T &Kato H (2010) Deleting two C-terminal alphahelices is effective to crystallize the bacterial ABC transporter Escherichia coli MsbA complexed with AMPPNP. Acta Crystallogr D Biol Crystallogr 66, 319-329.
    • (2010) Acta Crystallogr D Biol Crystallogr , vol.66 , pp. 319-329
    • Terakado, K.1    Kodan, A.2    Nakano, H.3    Kimura, Y.4    Ueda, K.5    Nakatsu, T.6    Kato, H.7
  • 50
    • 70349785109 scopus 로고    scopus 로고
    • Conformational Cycle of the ABC Transporter MsbA in Liposomes: Detailed Analysis Using Double Electron-Electron Resonance Spectroscopy
    • Zou P, Bortolus M & Mchaourab S H (2009) Conformational Cycle of the ABC Transporter MsbA in Liposomes: Detailed Analysis Using Double Electron-Electron Resonance Spectroscopy. J Mol Biol 393, 586-597
    • (2009) J Mol Biol , vol.393 , pp. 586-597
    • Zou, P.1    Bortolus, M.2    McHaourab, S.H.3
  • 51
    • 33748644877 scopus 로고    scopus 로고
    • Structure of a bacterial multidrug ABC transporter
    • Dawson R J & Locher K P (2006) Structure of a bacterial multidrug ABC transporter. Nature 443, 180-185
    • (2006) Nature , vol.443 , pp. 180-185
    • Dawson, R.J.1    Locher, K.P.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.