Pyrrolinone-based peptidomimetics. "Let the Enzyme or Receptor be the Judge"

Accounts of Chemical Research

Volumn 44, Issue 3, 2011, Pages 180-193

  Smith III, Amos B ^a   Charnley, Adam K ^a   Hirschmann, Ralph ^a  

^a UNIVERSITY OF PENNSYLVANIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

HLA DR1 ANTIGEN; HUMAN IMMUNODEFICIENCY VIRUS PROTEINASE; HUMAN IMMUNODEFICIENCY VIRUS PROTEINASE INHIBITOR; MATRIX METALLOPROTEINASE; P16 PROTEASE, HUMAN IMMUNODEFICIENCY VIRUS 1; PEPTIDE; PEPTIDOMIMETIC AGENT; POLYPROLINE; PYRROLE DERIVATIVE; RENIN; SOMATOSTATIN;

ANIMAL; ARTICLE; BINDING SITE; CHEMICAL STRUCTURE; CHEMISTRY; CONFORMATION; DOG; DRUG ANTAGONISM; DRUG DESIGN; HUMAN; HYDROGEN BOND; METABOLISM; PROTEIN BINDING; PROTEIN SECONDARY STRUCTURE; STEREOISOMERISM; STRUCTURE ACTIVITY RELATION; SYNTHESIS; X RAY CRYSTALLOGRAPHY;

ANIMALS; BINDING SITES; CRYSTALLOGRAPHY, X-RAY; DOGS; DRUG DESIGN; HIV PROTEASE; HIV PROTEASE INHIBITORS; HLA-DR1 ANTIGEN; HUMANS; HYDROGEN BONDING; MATRIX METALLOPROTEINASES; MODELS, MOLECULAR; MOLECULAR CONFORMATION; PEPTIDES; PEPTIDOMIMETICS; PROTEIN BINDING; PROTEIN STRUCTURE, SECONDARY; PYRROLES; RENIN; SOMATOSTATIN; STEREOISOMERISM; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 79952858926     PISSN: 00014842     EISSN: 15204898     Source Type: Journal    
DOI: 10.1021/ar1001186     Document Type: Article

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