A second-generation synthesis of polypyrrolinone nonpeptidomimetics: Prelude to the synthesis of polypyrrolinones on solid support

Organic Letters

Volumn 2, Issue 14, 2000, Pages 2037-2040

  Smith III, Amos B ^a   Liu, Hu ^a   Hirschmann, Ralph ^a  

^a UNIVERSITY OF PENNSYLVANIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

2 PYRROLIDONE DERIVATIVE; ASPARTIC PROTEINASE; DIMETHYL SULFOXIDE; PROTEINASE INHIBITOR;

ARTICLE; CHEMISTRY; DRUG ANTAGONISM; ENZYMOLOGY; HUMAN IMMUNODEFICIENCY VIRUS 1; OXIDATION REDUCTION REACTION; SYNTHESIS;

ASPARTIC ENDOPEPTIDASES; DIMETHYL SULFOXIDE; HIV PROTEASE INHIBITORS; HIV-1; OXIDATION-REDUCTION; PYRROLIDINONES;

EID: 0034644007     PISSN: 15237060     EISSN: None     Source Type: Journal    
DOI: 10.1021/ol0059293     Document Type: Article

References (28)

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15. 4b
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17. To access the bispyrrolinone aldehyde [e.g., 3 (n = 2)]. 4 N HCl and heating are required.
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